Abstract：
:The induction of experimental arthritis in rhesus monkeys was studied by intradermal immunization of bovine type II collagen and antigens derived from Mycobacterium tuberculosis, Streptococcus pyogenes, and Eubacterium aerofaciens. The tested bacterial antigens proved to be not arthrogenic. Bovine type II collagen induced clinical arthritis in 50% of the rhesus monkeys. Type II collagen induced arthritis in rhesus monkeys proved to be a potential model to study clinical, serological, histological, genetic, and immunologic features associated with human RA.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Bakker NP,van Erck MG,Zurcher C,Faaber P,Lemmens A,Hazenberg M,Bontrop RE,Jonker Mdoi
10.1007/BF02274777subject
Has Abstractpub_date
1990-01-01 00:00:00pages
21-9issue
1eissn
0172-8172issn
1437-160Xjournal_volume
10pub_type
杂志文章abstract：AIM:The aim of this study was to assess the efficacy of long-term azathioprine and steroids for treatment of severe nephritis in children with Henoch-Schönlein purpura (HSP). METHODS:Analysis of case records of children with HSP followed up for a mean duration of 4.7 years (range 6 months-6.5 years) was performed. All...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-002-0208-9
更新日期：2002-08-01 00:00:00
abstract：:To determine the "hand anatomic index" (HAI--a quantitative measure of hand deformity) in systemic sclerosis (scleroderma) and to compare it with the other measures of hand deformity and functional impairment. The HAI (measure of open hand span minus closed hand span/lateral height of hand) was determined in 30 patien...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-005-0058-3
更新日期：2006-03-01 00:00:00
abstract：:Resveratrol (trans-3,4'-trihydroxystilbene), a natural phytoalexin, possesses anti-inflammatory, anti-proliferative, and immunomodulatory properties and has the potential for treating inflammatory disorders. The present study was designed to investigate the effects of resveratrol on TNF-α-induced inflammatory cytokine...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-012-2657-0
更新日期：2013-07-01 00:00:00
abstract：:Crystalglobulinemia is an extremely rare pathology that is associated in most cases with plasma cell dyscrasia, mainly multiple myeloma. In most cases, it may be the manifestation of incipient gammopathy or it manifests shortly after diagnosis. We report a patient with ischemic lesions of thrombotic origin in lower li...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-020-04620-6
更新日期：2020-08-01 00:00:00
abstract：:The purpose of this study was to investigate specifically the correlation of hand functions determined by Duruoz hand index (DHI) with radiological findings and disease activity in rheumatoid arthritis (RA) patients. Forty-eight RA patients were evaluated with DHI questionnaire, disease activity score (DAS) 28 and mod...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-007-0461-z
更新日期：2008-03-01 00:00:00
abstract：:The aim of this study was to investigate the percentage of regulatory T cells and the correlation with clinical activity in Behçet's disease. Forty Behçet's disease (BD) patients, 18 males and 22 females, were included in the study. The patients were diagnosed according to the published BD criteria. Twenty age- and se...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-013-2835-8
更新日期：2013-12-01 00:00:00
abstract：OBJECTIVE:Neprilysin (neutral endopeptidase, 3:4:24:11, CD10) (NEP) is a Zn metallopeptidase linked to controlling inflammation through the degradation of neuropeptides involved in neurogenic inflammation of chronic rheumatic diseases. The aim of our study was to evaluate circulating activity and cellular expression of...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-004-0447-z
更新日期：2005-06-01 00:00:00
abstract：:The atrioventricular conduction time (P-R interval) was determined in 189 women and 90 men with rheumatoid arthritis (RA). Only three women and one man were found to have pathological prolongation of the P-R interval. However, a significant prolongation of the P-R interval, within normal range, was seen in women with ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00541337
更新日期：1985-01-01 00:00:00
abstract：OBJECTIVE:The prevalence of dermatophytic infections in rheumatoid arthritis is unknown. This study investigated the prevalence of dermatophytosis in patients with rheumatoid arthritis and the relationship between sulfasalazine, low-dose methotrexate and steroid therapy. METHODS:We examined 53 consecutive patients wit...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-002-0238-3
更新日期：2003-01-01 00:00:00
abstract：:Previous studies have demonstrated an increased risk of breast cancer among patients with systemic sclerosis (scleroderma). To describe the clinical characteristics of 21 patients with both systemic sclerosis and breast cancer, and compare their risk factors to female scleroderma patients without breast cancer, in a p...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-008-0540-9
更新日期：2008-07-01 00:00:00
abstract：:Monogenic autoinflammatory syndromes are a rare group of disorders characterized by periodic episodes of systemic inflammation of endogenous origin. Sometimes, these diseases may present with features akin to vasculitis. We conducted a literature review on such vasculitic manifestations in described monogenic autoinfl...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-017-3839-6
更新日期：2018-01-01 00:00:00
abstract：:The clinical use of pulsed electromagnetic fields (PEMF) in osteoarticular pathology is widely extended, although the mechanisms involved are unknown. The aim of this study was to evaluate the action of a new protocol of treatment with PEMF on liquid medium cultures of fibroblast-like cells derivates of mononuclear pe...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1488-0
更新日期：2011-10-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to investigate the relationships among bone mineral densities (BMD) in the calcaneus and leg activity of daily living (L-ADL) in rheumatoid arthritis (RA) patients. METHODS:We measured and compared calcaneus BMD using single X-ray absorptiometry and lumbar spine and femoral neck BM...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-003-0421-1
更新日期：2005-04-01 00:00:00
abstract：:Systemic sclerosis (SSc) is a chronic autoimmune connective tissue disease. Of the numerous organ manifestations, involvement of the upper and lower gastrointestinal tract (GIT) appears to be the most frequent with regard to the clinical symptoms. However, as the frequency and clinical relevance of GI involvement in p...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-1988-6
更新日期：2012-08-01 00:00:00
abstract：:Familial Mediterranean fever (FMF) is a self-limited disease characterized by fever and polyserositis attacks. Arthritis caused by synovitis is either in acute monoarthritis or chronic mono-oligoarthritis form, usually affecting the lower extremities. Another potential but rare form of involvement is spondyloarthropat...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-008-0616-6
更新日期：2008-11-01 00:00:00
abstract：:To investigate the effects of TNF-alpha -308, -238 promoter polymorphisms on TNF-alpha transcription in B27 positive Chinese patients with ankylosing spondylitis (AS). The possible relationship between polymorphisms, MHC antigens, and quantitative TNF-alpha mRNA expression were evaluated. Single nucleotide polymorphis...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-008-0671-z
更新日期：2008-12-01 00:00:00
abstract：:This study was performed to identify the role of cholinergic stimulation on changes of intracellular calcium concentrations as intracellular messenger of neuroimmune interaction. Incubation of PBMC with acetylcholine (ACh) leads to Ca(2+) oscillations in healthy controls. PBMC from rheumatoid arthritis (RA) patients e...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-008-0723-4
更新日期：2009-03-01 00:00:00
abstract：:Articular involvement is a frequent extrahepatic manifestation of hepatitis C virus (HCV) infection. The distinction between HCV-related polyarthropathy and true RA may be very difficult, especially with recent onset RA before articular damage and erosions develop. The objective of the study is to assess the diagnosti...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-1225-8
更新日期：2011-01-01 00:00:00
abstract：:We have investigated the role of the Th17-related cytokines interleukin-17A (IL-17A), IL-21, and IL-23 in spondyloarthritis (SpA) by examining their association with disease activity and magnetic resonance imaging (MRI) findings in patients with SpA (n = 80). Furthermore, to investigate the cellular origins of the cyt...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1655-3
更新日期：2012-02-01 00:00:00
abstract：:Uveitis in juvenile idiopathic arthritis (JIA) is frequently associated with the development of complications and visual loss. Topical corticosteroids are the first-choice therapy, and immunosuppression is commonly used. However, treatment has not been standardized. Representatives from the German Ophthalmological Soc...
journal_title：Rheumatology international
pub_type： 杂志文章,实务指引,评审
doi：10.1007/s00296-011-2126-1
更新日期：2012-05-01 00:00:00
abstract：:Acute leukemia is uncommonly seen with rheumatoid arthritis during or following treatment with low-dose methotrexate, a safe and effective treatment for the arthritic condition. We describe here a 68-year-old woman with rheumatoid arthritis who developed acute erythroleukemia during low-dose methotrexate therapy (tota...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-004-0502-9
更新日期：2005-05-01 00:00:00
abstract：:Individual differences in adjustment during a disease's course determine psychological response and outcome. This study aimed to investigate prospectively whether coping with health stressors and self-sacrificing defense style could predict psychological adjustment and health-related quality of life (HRQoL) in patient...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-014-3134-8
更新日期：2015-04-01 00:00:00
abstract：:The aim of this study was to compare clinical symptoms, perceived health status, health resource use and psychosocial features in fibromyalgia (FM) patients at different health care levels. A total of 315 participants were recruited from primary care (PC) (n=101) and rheumatology settings (RS) (n=214). Subjects comple...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-008-0818-y
更新日期：2009-08-01 00:00:00
abstract：:Vasculitides associated with anti-neutrophil cytoplasmic antibodies are heterogeneous, systemic, low prevalence and high morbidity and mortality entities. They include granulomatosis with polyangiitis, microscopic polyangiitis and eosinophilic granulomatosis with polyangiitis. In Latin America, there are few descripti...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-020-04631-3
更新日期：2020-08-01 00:00:00
abstract：:Activated T lymphocytes (Ia+ T-cells) in peripheral blood are associated with immune stimulation. We found the percentages of these cells significantly increased in 95% of rheumatoid arthritis (RA) patients. Our studies showed no relation between the percentages of these cells in peripheral blood and concurrent erythr...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00272435
更新日期：1988-01-01 00:00:00
abstract：:Rheumatoid arthritis (RA) is a chronic systemic disorder characterized by the development through angiogenesis, which is dependent on endothelial cell activation, migration and proliferation and CCL21 plays an important role in this pathology. Currently, CCL21 gene polymorphism studies on rheumatoid arthritis are scar...
journal_title：Rheumatology international
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00296-017-3784-4
更新日期：2017-10-01 00:00:00
abstract：:To determine the forms and characteristics of rheumatic diseases whose initial presentation mimics septic arthritis. Retrospective study of 398 patients hospitalized between 1979 and 2005 for arthritis diagnosed and treated as septic. In 10 cases, initial presentation of a rheumatic disease was highly suggestive of se...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-012-2364-x
更新日期：2013-08-01 00:00:00
abstract：:An imbalance in pro- and anti-inflammatory cytokines is suggested to contribute to tissue damage in rheumatoid arthritis (RA). This study was aimed at investigating profiles of cytokines in circulation and cytokines produced by mitogen-stimulated peripheral blood mononuclear cells (PBMC) in RA patients and healthy con...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-017-3774-6
更新日期：2017-10-01 00:00:00
abstract：:Women in reproductive age with rheumatic diseases (RD) are especially vulnerable for depression and anxiety which negatively impacts the pregnancy, birth, and RD. The purpose of this study is to describe the frequency of anxiety and depression symptoms employing the Hospital Anxiety and Depression Scale (HADS) in wome...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-020-04591-8
更新日期：2020-09-01 00:00:00
abstract：:An immunoglobulin-independent deposition of the complement (C) components C4 and C3 occurs on rat kidney medullary structures, when sera of patients with various inflammatory diseases are studied by indirect immunofluorescence. The diagnostic value of this new test (C4-C3-IFT) for polymyalgia rheumatica (PMR) is stres...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00271838
更新日期：1988-01-01 00:00:00
