Abstract:
:We report our experience and hypothesis on the diagnosis and treatment of patients with vasculitis who are simultaneously diagnosed with serum-positive cytomegalovirus (CMV) immunoglobulin (Ig)M antibodies and negative CMV DNA polymerase chain reaction (PCR). It remains unknown how to treat this kind of "phantom" CMV infection. In a patient diagnosed with Henoch-Schönlein vasculitis, CMV IgM titers were increased while angiitis and renal function deteriorated. Empiric treatment of phantom CMV infection with ganciclovir in this CMV IgM-positive and PCR-negative patient resulted in complete vasculitis remission, serum CMV antibody seroconversion, and renal function improvement. These results imply something more than coincidence.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Katsanos KH,Kostoula A,Katopodis KP,Siamopoulos KCdoi
10.1007/s00296-004-0522-5subject
Has Abstractpub_date
2005-10-01 00:00:00pages
631-2issue
8eissn
0172-8172issn
1437-160Xjournal_volume
25pub_type
杂志文章abstract:BACKGROUND:Axillary lymph nodes (ALNs) are often seen on chest computed tomography (CT) in rheumatoid arthritis (RA) patients. Early reports described lymphadenopathy as one of the systemic manifestations rather than regional lymphadenopathy secondary to drainage from the affected joints. Subsequently, the importance o...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-018-3992-6
更新日期:2018-06-01 00:00:00
abstract::E-selectin and intercellular adhesion molecule (ICAM)-1 are crucial to the inflammatory response in chronic inflammatory arthritis. Soluble (s) levels of these molecules in sera and synovial fluid (SF) correlate with some clinical parameters and synovial tissue expression of the same molecules in rheumatoid arthritis....
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-002-0212-0
更新日期:2002-09-01 00:00:00
abstract::Balneotherapeutic applications to treat rheumatic diseases have a long-term tradition and are based on established scientific principles, and the majority of rheumatic diseases most frequently include balneotherapy. However, as other therapeutic strategies, balneological interventions require scientific proof of their...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-005-0019-x
更新日期:2006-04-01 00:00:00
abstract::Activation of opioid receptors on peripheral sensory nerve terminals by opioid peptides that are produced and released from immune cells can result in inhibition of inflammatory pain. This study tests the hypothesis that postoperative pain is attenuated endogenously through a local sympathetic neurotransmitter-activat...
journal_title:Rheumatology international
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00296-010-1489-z
更新日期:2011-10-01 00:00:00
abstract::We investigated the overall frequency of anti-phospholipid syndrome (APS) occurrence in Korean patients with consecutively detected anti-phospholipid antibodies with an interval of 12 weeks (persistent aPLs). We retrospectively reviewed the results of blood tests of aPLs in 14,889 patients in whom aPL tests were perfo...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-019-04318-4
更新日期:2019-08-01 00:00:00
abstract::We investigated the effect of chrysotherapy on the Fc and complement receptor binding activity of peripheral blood (PB) monocytes and peritoneal (PE) macrophages isolated from normal rats and rats with adjuvant induced arthritis. The adjuvant induced severe disease in Dark Agouti (DA) rats and less marked disease in J...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00270454
更新日期:1988-01-01 00:00:00
abstract::Ankylosing spondylitis (AS) is a chronic inflammatory disease primarily involving the spine and sacroiliac joint and rarely the kidneys. This study aimed to define the clinical and histological features and biology of renal disease in AS. We reviewed the medical records of 681 patients diagnosed with AS from November ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-012-2624-9
更新日期:2013-07-01 00:00:00
abstract::To investigate whether anti-inflammatory effects of HMG-CoA reductase inhibitor simvastatin (SMV) in rheumatoid arthritis (RA) is mediated by Toll-like receptor-2 (TLR-2) signal via inhibiting activation of RhoA, a small Rho GTPase that plays an important role in inflammatory responses. Peripheral blood monocytes from...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1510-6
更新日期:2011-11-01 00:00:00
abstract::Addison's disease is an autoimmune process. However, Addison's disease associated with connective tissue diseases (CTD) is only occasionally reported. Here, we report six cases of Addison's disease secondary to a variety of CTD, which include systemic lupus erythematosus, Takayasu arteritis, systemic sclerosis, ankylo...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0749-7
更新日期:2009-04-01 00:00:00
abstract::Celiac disease (CD) is an autoimmune systemic disease characterized by not only gastrointestinal but also extraintestinal manifestations. The aim of our study was to do a serological screening for CD, by IgA endomysial antibodies (EmA), in patients with unexplained articular manifestations. Two hundred and eleven pati...
journal_title:Rheumatology international
pub_type: 杂志文章,多中心研究
doi:10.1007/s00296-013-2906-x
更新日期:2014-05-01 00:00:00
abstract::The goal of this study was to investigate the persistence with biological drugs in patients treated in rheumatology practices in Germany. This study included patients diagnosed with rheumatoid arthritis (RA), psoriatic arthritis (PA), or ankylosing spondylitis (AS) who received a first prescription of biological drugs...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-018-4194-y
更新日期:2019-03-01 00:00:00
abstract::The objective of this study was to report 11 cases of propylthiouracil (PTU)-induced autoimmune syndromes. We describe the clinical presentation, course, and outcome of 11 patients and compare clinical features between PTU-induced lupus and PTU-induced vasculitis. Of our 11 patients, 7 patients had vasculitis and 4 pa...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1675-z
更新日期:2012-03-01 00:00:00
abstract::Antibodies to citrullinated proteins have been described in patients with rheumatoid arthritis (RA) and these appear to be the most specific markers of the disease. Our objective was to determine the frequency of antibodies to cyclic citrullinated peptides (CCPs) in patients with RA and the association of anti-CCP ant...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0570-3
更新日期:2008-08-01 00:00:00
abstract::Using commercially available antigens, enzyme-linked immunosorbent assays (ELISAs) were set up to demonstrate antibodies of IgG class against Sm and SS-A. Anti-Sm antibodies were demonstrated in 40% of patients with systemic lupus erythematosus (SLE), in 12% of patients with SJögren's syndrome, in 6% of patients with ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00332564
更新日期:1991-01-01 00:00:00
abstract::Arachnoid ossificans is a rare type of chronic arachnoiditis characterised by the presence of calcification or ossification of the dura and arachnoid. There are a few reports of these findings in relation to various disease entities, but only one case has been reported in relation to ankylosing spondylitis. We describ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-011-2293-0
更新日期:2013-06-01 00:00:00
abstract::We have investigated the role of the Th17-related cytokines interleukin-17A (IL-17A), IL-21, and IL-23 in spondyloarthritis (SpA) by examining their association with disease activity and magnetic resonance imaging (MRI) findings in patients with SpA (n = 80). Furthermore, to investigate the cellular origins of the cyt...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1655-3
更新日期:2012-02-01 00:00:00
abstract::Protein synthesis in all cells is readily interrupted by environmental stresses such as hyperthermia. However, stressed cells also have mechanisms which, even under conditions where normal protein synthesis is completely inhibited, allow them to synthesise a group of highly conserved proteins--the so-called heat shock...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/BF00541323
更新日期:1990-01-01 00:00:00
abstract::Diffuse idiopathic skeletal hyperostosis (DISH) is difficult to distinguish from various forms of inflammatory arthritis, including psoriatic arthritis (PsA), rheumatoid arthritis, and ankylosing spondylitis. A 67-year-old Japanese male had been treated for psoriasis vulgaris for 13 years. Numbness of his right arm an...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1368-7
更新日期:2012-05-01 00:00:00
abstract::Fifty-five patients with systemic lupus erythematosus (SLE) were examined for antineutrophil cytoplasmic antibodies (ANCA) by indirect immunofluorescence (IIF). Enzyme-linked immunosorbent assay (ELISA) for ANCA against myeloperoxidase (MPO), lactoferrin (LF), proteinase 3 (PR3), elastase (HLE), and bactericidal/perme...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s002960100108
更新日期:2001-07-01 00:00:00
abstract::Objective of the study is to investigate how compliance during the first year of methotrexate (MTX) treatment in rheumatoid arthritis (RA) is influenced by the patients' perception of the necessity for and concern about MTX, the patients' functional disability, and the dose of MTX. A total of 126 RA patients completed...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-1160-8
更新日期:2010-09-01 00:00:00
abstract::Cyclooxygenase-2 (COX-2) is a key regulatory enzyme in the synthesis of prostanoids associated with trauma and inflammation. Upregulation of COX-2 in human lupus T cells resists anergy and apotosis. We investigated the COX-2 gene for functional variants that may influence susceptibility, clinical outcomes and severity...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-006-0162-z
更新日期:2006-11-01 00:00:00
abstract::A 41-year-old woman with SAPHO syndrome presented with numbness of her left arm followed by a generalized seizure. Computed tomography and magnetic resonance imaging of the brain revealed a small ring enhancing lesion in the right parietal lobe with adjacent meningeal thickening and enhancement. Surgical removal and h...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1464-8
更新日期:2012-06-01 00:00:00
abstract::Sarcoidosis is a chronic granulomatous inflammation. The clinical spectrum in childhood is heterogeneous. Angiotensin converting enzyme activity is used as a marker for disease activity. Human chitotriosidase is produced in macrophages. In this study, serum chitotriosidase levels were significantly higher in active sa...
journal_title:Rheumatology international
pub_type: 信件
doi:10.1007/s00296-007-0318-5
更新日期:2007-10-01 00:00:00
abstract::Numerous studies have focused on the significance of modern marker proteins in the synovial fluid of the knee joint and in the serum both, for osteoarthritis (OA) and rheumatoid arthritis (RA). The relationship between the serum concentrations and the concentrations in the synovial fluid is still unclear. Synovial flu...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-005-0006-2
更新日期:2006-03-01 00:00:00
abstract::Familial Mediterranean fever is characterized by self-limited attacks of serositis and arthritis. However, substantial number of patients suffer from chronic complications of this disease, primarily involving musculoskeletal system. Treatment for these complications is challenging due to limited evidence. Interleukin-...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-019-04490-7
更新日期:2020-01-01 00:00:00
abstract::The aim of the study was the thermovisual comparison of mean temperature of hand surface changes after local cryotherapy with vapors of nitrogen (-160°C) and cold air (-30°C). Forty-seven patients with rheumatoid arthritis (39 women and 8 men; average age 56.2 ± 10.5 years) were included in the study. They had the app...
journal_title:Rheumatology international
pub_type: 临床试验,杂志文章
doi:10.1007/s00296-011-2078-5
更新日期:2012-10-01 00:00:00
abstract::Wells' syndrome is a multifaceted dermatosis with a wide morphological spectrum, ranging from characteristic cellulitis-like erythema and papula to an unusual presentation of vesicles and pustules. The most important elements for diagnosis are erythemal plaques and histological picture of eosinophilic infiltration of ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-011-1809-y
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVES:To evaluate the prevalence and annual incidence of clinically-manifest vertebral fractures among patients with ankylosing spondylitis (AS). METHOD:Coordinated by the Ankylosing Spondylitis International Federation, a self-administered general questionnaire which included some questions on gender, age, age a...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-004-0556-8
更新日期:2006-01-01 00:00:00
abstract::The objective of the study was to investigate the possibility whether the in vitro treatment with vitamin D3 can restore the impaired expression of protein kinase C (PKC) isoenzymes and IL-2 production in the lymphocytes of patients with systemic lupus erythematosus (SLE). Purified T lymphocytes from 14 patients with ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-013-2751-y
更新日期:2014-05-01 00:00:00
abstract::Microscopic polyangiitis is a small-vessel necrotizing vasculitis associated with anti-neutrophil cytoplasmic antibodies and presents itself with glomerulonephritis and hemorrhagic pulmonary capillaritis. Peripheral nervous system involvement is common in anti-neutrophil cytoplasmic antibodies-associated vasculitis, b...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-016-3424-4
更新日期:2016-07-01 00:00:00