Abstract：
:The current clinical and laboratory parameters of Takayasu arteritis (TA) are insufficient for proper assessment of disease activity. The aims of this study were to investigate the markers of endothelial injury and repair, including circulating endothelial cell (CEC), circulating endothelial progenitor cell (CEPC) and vascular endothelial growth factor (VEGF), and evaluate their associations with disease activity in patients with TA. Thirty-two patients with TA and 30 healthy age- and sex-matched controls were included in this study. Disease activity was assessed in TA patients using various tools, including Kerr's criteria, the Indian Takayasu's Arteritis Scoring (ITAS2010) and physician's global assessment (PGA). CECs and CEPCs were measured by flow cytometry, and VEGF was measured using an enzyme-linked immunosorbent assay. The CEC level was found to be higher in TA patients than in the healthy controls (HC) (p < 0.001). There was no significant difference in CEC level between the active and inactive patients, but its level was slightly correlated with C-reactive protein (CRP) level. CEPC and VEGF levels in TA patients with active disease were higher than those in the inactive patients and HC. CEPC and VEGF levels were positively correlated with ITAS-CRP and PGA scores. This study shows increased level of CEC in patients with TA. It also suggests that the CEPC and VEGF levels may be correlated with disease activity.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Dogan S,Piskin O,Solmaz D,Akar S,Gulcu A,Yuksel F,Cakır V,Sari I,Akkoc N,Onen Fdoi
10.1007/s00296-013-2937-3subject
Has Abstractpub_date
2014-08-01 00:00:00pages
1129-38issue
8eissn
0172-8172issn
1437-160Xjournal_volume
34pub_type
杂志文章abstract：:The expressions of some terminal glycotopes of synovial immunoglobulins G, A, and M were analysed in relation to rheumatoid arthritis (RA) progression defined according to early and advanced radiological changes in patients' hands. The relative amounts of terminal monosaccharides were determined by lectin-immunoblotti...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-1139-5
更新日期：2010-08-01 00:00:00
abstract：:We present a 10-year-old girl who had been diagnosed with juvenile idiopathic arthritis 5 years before and who experienced a flare of arthritis affecting one knee while she was off medication for almost 3 years. Seronegative Lyme arthritis had to be diagnosed based on the detection of Borrelia burgdorferi DNA in synov...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-007-0333-6
更新日期：2007-09-01 00:00:00
abstract：:Our study was aimed to clarify an association between gastrointestinal (GI) amyloid-positive area and various kinds of factors including renal function in reactive amyloidosis associated with rheumatoid arthritis (RA). Twenty-five patients with an established diagnosis of reactive AA amyloidosis participated in the st...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1719-4
更新日期：2012-04-01 00:00:00
abstract：:Plasma fibronectin (FN) was measured in 17 patients with essential mixed cryoglobulinaemia (EMC) and in 17 normal subjects by single radial immunodiffusion (RID) and enzyme-linked immunosorbent assay (ELISA). In 9 patients the presence of FN in the cryoprecipitates was also assessed by immunoblotting. In the EMC group...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00541379
更新日期：1987-01-01 00:00:00
abstract：:To describe the characteristics of patients receiving belimumab, overall patterns of systemic lupus erythematosus (SLE) care, clinical outcomes, and changes in glucocorticoid dose following 6 months of therapy with belimumab, and healthcare resource utilization in belimumab users in Canadian clinical practice settings...
journal_title：Rheumatology international
pub_type： 杂志文章,多中心研究
doi：10.1007/s00296-017-3682-9
更新日期：2017-06-01 00:00:00
abstract：:In a study of 199 patients with rheumatoid arthritis, 68% were found to have tried 'alternative treatments'. Some treatments (acupuncture and faith healing) gave subjective benefit in nearly half those who tried them and were considered to be better than others (such as copper bracelets). No adverse reactions were rep...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00541593
更新日期：1983-01-01 00:00:00
abstract：:Behçet's disease (BD) commonly presents with articular manifestations and thrombotic vasculopathy. Arthritis of BD characteristically demonstrates a recurrent and nondestructive course. The pathobiological basis of the thrombotic vasculopathy and protective factors against cartilage destruction in arthritis of BD have...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-003-0324-1
更新日期：2004-03-01 00:00:00
abstract：:There is still debate on whether inflammatory pseudotumor should be considered benign or malignant. This lesion has only been reported twice in bone, apart from cases complicating foreign body reaction to joint replacement arthroplasty. We report here a third case, localized at the sacrum. A 31-year-old man had inflam...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-003-0365-5
更新日期：2004-05-01 00:00:00
abstract：:Patients with rheumatoid arthritis (RA) showed significantly (P < 0.01) increased numbers of granulocytes in their peripheral blood compared with normal donors and patients with osteoarthritis, and this finding correlated with interleukin-6 and C-reactive protein levels and active joint score. Then, 17 patients with R...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00290518
更新日期：1996-01-01 00:00:00
abstract：:Nailfold videocapillaroscopy was performed in 21 controls (C) and 21 patients (P) with systemic lupus erythematosus (SLE) classified according to the American College of Rheumatology, with, at least, 1 year of diagnosed disease and having low activity (MEX-SLEDAI) and sequel (SLICC) indexes at the time of the examinat...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-005-0033-z
更新日期：2006-05-01 00:00:00
abstract：:Osteomyelitis variolosa is an osteoarticular complication of small pox infection. We are presenting a case of osteomyelitis variolosa, who presented to us with fracture of ankle on the involved side with other orthopedic sequelae of small pox infection, which he contracted during his childhood period. We have discusse...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-2194-2
更新日期：2012-11-01 00:00:00
abstract：:Life expectancy in autoimmune rheumatic diseases (ARDs) remains lower compared to the general population, due to various comoborbidities. Cardiovascular disease (CVD) represents the main contributor to premature mortality. Conventional and biologic disease-modifying antirheumatic drugs (DMARDs) have considerably impro...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-018-4004-6
更新日期：2018-06-01 00:00:00
abstract：:Various surgical procedures including percutaneous and open release and arthroscopic procedures have been described to treat recalcitrant tennis elbow. We present the outcome of Boyd-McLeod surgical procedure for tennis elbow resistant to non-operative treatment in twenty-seven patients (twenty-nine limbs). Boyd McLeo...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1450-1
更新日期：2011-08-01 00:00:00
abstract：:The fibromyalgia syndrome (FMS) is a chronic, widespread pain disorder of unknown etiology. It has been suggest that familial component, environmental factors, endocrine and neurotransmitter alterations, and psychological factors may contribute to the development of FMS. The role of melatonin in FMS is unclear. Some s...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-2315-y
更新日期：2013-06-01 00:00:00
abstract：:The assessment of skin fibrosis is vital for the diagnosis and monitoring of treatment in the systemic sclerosis (SSc)-a severe autoimmune disease. The elastography is a technique of skin fibrosis assessment through the evaluation of skin strain. We compared the efficacy of the shear wave elastography (SWE) and common...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-020-04539-y
更新日期：2020-05-01 00:00:00
abstract：:Several studies of rheumatoid arthritis (RA) incidence and prevalence indicate that occurrence of the disease varies significantly among different populations. We aimed to estimate the prevalence and incidence of RA in South Korea. We used Korean National Health Insurance (NHI) claims data to estimate the prevalence o...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-012-2590-2
更新日期：2013-06-01 00:00:00
abstract：:The mechanisms of male idiopathic osteoporosis are little known. We evaluated bone mineral loss by dual-energy X-ray absorptiometry and determined its cortical or trabecular nature in a cohort of men with idiopathic osteoporosis with fractures. Thirty-nine men (mean age 60 ± 13 years), with negative investigations for...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-2076-7
更新日期：2012-10-01 00:00:00
abstract：:Several studies have shown a negative association between smoking and primary Sjögren's syndrome (pSS), and smoking may interfere with the immune response. The purpose of this study was to investigate if smoking affects disease activity and disease phenotype in pSS. In this cross-sectional study, consecutive pSS patie...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-019-04335-3
更新日期：2019-09-01 00:00:00
abstract：:In recent years, scientific efforts on the topic "gout" have focused on pathogenetic aspects. This has opened new strategies of anti-inflammatory therapy and has improved urate-lowering therapy. So far, a scientometric analysis of the topic "gout" has not been generated despite an increased need for it in times of mod...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-013-2805-1
更新日期：2013-11-01 00:00:00
abstract：:Juvenile idiopathic arthritis (JIA) is the most common diagnosis in children and adolescents with rheumatic disorders. In many children and adolescents, JIA is successfully treated with non-steroidal anti-inflammatory drugs (NSAID) and physiotherapy. However, in a significant number of cases the disease is resistant t...
journal_title：Rheumatology international
pub_type： 杂志文章,实务指引
doi：10.1007/s00296-004-0537-y
更新日期：2005-04-01 00:00:00
abstract：:The capillaroscopic pattern in paraneoplastic Raynaud's phenomenon (RP) has not been investigated systematically and is not well-defined. Here, we present three case reports of patients with paraneoplastic rheumatic conditions, manifested with severe secondary RP with emphasis upon capillaroscopic findings. The first ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1715-8
更新日期：2013-06-01 00:00:00
abstract：:Pure red cell aplasia (PRCA) is a disease with important relationships to autoimmune mechanisms. Although some autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus, have been associated with PRCA, until this point no studies have described the association between PRCA and primary antiphos...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1387-4
更新日期：2012-05-01 00:00:00
abstract：:Chronic inflammation starting early in life and continuing into adulthood may predispose children with Juvenile Idiopathic Arthritis (JIA) to cardiovascular (CV) complications. To compare non-invasive CV risk markers- left ventricular mass index (LVMi), brachial artery flow mediated dilatation (FMD) and carotid artery...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-020-04689-z
更新日期：2021-02-01 00:00:00
abstract：:The objective of this study is to investigate the relationship between clinical features of ankylosing spondylitis (AS) and HLA-B27 status or its subtypes. Clinical data and blood samples were collected with patients' informed consent. Luminex liquid array combining polymerase chain reaction-sequence specific oligonuc...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-008-0743-0
更新日期：2009-02-01 00:00:00
abstract：:The aim of the study is to study the relationship between androgen levels and bone mineral density (BMD) in elderly Arab males. Forty-five elderly Arab males underwent Dual X-ray absorptiometry for measurement of BMD. The outcomes were defined as per WHO description. Assays for testosterone (T), gonadotropins (LH and ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-0970-z
更新日期：2010-01-01 00:00:00
abstract：:HLA-DR antigens were determined in 111 patients with classic or definite rheumatoid arthritis. HLA-DR4 was significantly (P corr. less than 10(-6] increased in patients with rheumatoid arthritis (54%) compared with controls (23.2%). HLA-DR 5 was decreased in rheumatoid arthritis (12.6% vs 26.4% of controls); however, ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00541190
更新日期：1983-01-01 00:00:00
abstract：:Rheumatology has its roots in ancient Greece. Hippocrates and other prominent Greek (Hellenes) physicians in ancient times, Hellenistic, Roman, and Byzantine period were acute observers of disease course and of patients and were able to define many disorders. They wrote books on various aspects of medicine and these w...
journal_title：Rheumatology international
pub_type： 历史文章,杂志文章,评审
doi：10.1007/s00296-019-04261-4
更新日期：2019-06-01 00:00:00
abstract：OBJECTIVE:Recent studies revealed trisomy 7 as a chromosomal abnormality in non-neoplastic disorders such as rheumatoid arthritis (RA). In the present study, we investigated the presence of trisomy 7 in the synovial fluid cells of patients with RA using fluorescence in situ hybridisation (FISH) analysis. METHODS:Synov...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-004-0477-6
更新日期：2005-10-01 00:00:00
abstract：:This study aims to elucidate plasma oxidant/antioxidant status in patients with rheumatoid arthritis (RA). Fasting blood samples were obtained from 24 patients with RA and 20 control subjects. Antioxidant potential (AOP) value, nonenzymatic superoxide radical scavenger activity (NSSA), and malondialdehyde (MDA) levels...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s002960050097
更新日期：1999-01-01 00:00:00
abstract：:The risk of herpes zoster among patients with juvenile idiopathic arthritis (JIA) exposed to biologics has not been evaluated. We determined incidence rates of herpes zoster among children with JIA in correlation with medication at time of occurrence and total drug exposure. The German biologics register database was ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-014-3197-6
更新日期：2015-03-01 00:00:00
