Abstract:
:The mechanisms of male idiopathic osteoporosis are little known. We evaluated bone mineral loss by dual-energy X-ray absorptiometry and determined its cortical or trabecular nature in a cohort of men with idiopathic osteoporosis with fractures. Thirty-nine men (mean age 60 ± 13 years), with negative investigations for the cause of osteoporosis, were studied. All had fragility fractures: vertebral 51%, peripheral 25%, and both types 24%. Bone density was measured at the lumbar spine (L2-L4), total hip and whole body. The limb/axial skeleton (spine + hips) and hip/L2-L4 BMD ratios were calculated. Serum 25-hydroxy-vitamin D, PTH, bone alkaline phosphatase and CTX were measured. Bone mineral loss predominated at the lumbar spine (mean L2-L4 T-score -3 ± 0.93, mean total hip T-score -1.87 ± 0.75). Limb/axial skeleton and total hip/L2-L4 BMD were strongly correlated, but not hip and spine BMD. The ratio values were widely scattered, indicating markedly heterogeneous bone loss. Vitamin D, PTH, bone alkaline phosphatase and CTX levels did not differ between predominantly trabecular and cortical osteoporosis. Bone mineral density measurement in male idiopathic osteoporosis with fractures demonstrated that bone loss predominated in the spine and that it was very heterogeneous, principally affecting cortical or trabecular bone depending on the patient.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Laroche Mdoi
10.1007/s00296-011-2076-7subject
Has Abstractpub_date
2012-10-01 00:00:00pages
3093-6issue
10eissn
0172-8172issn
1437-160Xjournal_volume
32pub_type
杂志文章abstract::A recent genome-wide association study revealed that there is an association between serum uric acid (SUA) levels and rs2544390, a common variant in low-density lipoprotein-related protein 2 (LRP2/Megalin) gene. Two other variants of LRP2, rs2229268 and rs3755166, are also found to have associations with dyslipidemia ...
journal_title:Rheumatology international
pub_type: 杂志文章,多中心研究
doi:10.1007/s00296-013-2924-8
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abstract::Citrulline antibody, nowadays, is a new item which has been the center of attention due to its much more specificity to diagnose RA. The aim of the present study was to evaluate the efficacy and accuracy of anti-citrulline antibody test in RA diagnosis among hospitalized patients in Iran. Through a case-control study,...
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journal_title:Rheumatology international
pub_type: 杂志文章
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journal_title:Rheumatology international
pub_type: 杂志文章,meta分析,评审
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journal_title:Rheumatology international
pub_type: 杂志文章
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更新日期:2010-04-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章,评审
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-019-04375-9
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pub_type: 杂志文章
doi:10.1007/s00296-013-2786-0
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journal_title:Rheumatology international
pub_type: 杂志文章
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0743-0
更新日期:2009-02-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
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journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-007-0381-y
更新日期:2007-11-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0758-6
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pub_type: 杂志文章,随机对照试验
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journal_title:Rheumatology international
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Rheumatology international
pub_type: 杂志文章
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更新日期:2018-03-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-018-4104-3
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1532-0
更新日期:2011-12-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-011-2139-9
更新日期:2013-01-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
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更新日期:1988-01-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-020-04762-7
更新日期:2021-01-02 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章,多中心研究
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更新日期:2016-03-01 00:00:00
abstract::The aim of this study was to evaluate whether the serum concentration of interleukin-6 (IL-6) reflects disease activity in ankylosing spondylitis (AS). A group of 271 AS patients were enrolled in the study, 261 of whom completed the entire protocol (201 males, 60 females, median age of 53 years). Serum IL-6 was measur...
journal_title:Rheumatology international
pub_type: 临床试验,杂志文章
doi:10.1007/s002960050066
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