当前位置： SCI文献检索 > RHEUMATOLOGY INTERNATIONAL期刊下所有文献 > HLA-DR antigens and disease patterns of rheumatoid arthritis.

HLA-DR antigens and disease patterns of rheumatoid arthritis.

Abstract：

:HLA-DR antigens were determined in 111 patients with classic or definite rheumatoid arthritis. HLA-DR4 was significantly (P corr. less than 10(-6] increased in patients with rheumatoid arthritis (54%) compared with controls (23.2%). HLA-DR 5 was decreased in rheumatoid arthritis (12.6% vs 26.4% of controls); however, the corrected P value was not significant. There were no significant differences with regard to various clinical, radiological and serological parameters between HLA-DR 4 positive and negative patients. However, a milder course of rheumatoid arthritis was observed in DR 7 positive patients: Patients with this antigen were associated significantly with seronegativity and low titers of IgM-rheumatoid factor. Despite a similar disease duration patients with DR 7 had a significantly lower number of joints with inflammatory arthritis (synovitic swelling with limitation of movement) and developed less frequently severe radiological changes as joint ankylosis than DR 7 negative patients. In addition to the well known association between rheumatoid arthritis and HLA-DR 4, our data indicate that HLA-DR 7 may have a protective effect on the course of rheumatoid arthritis.

journal_name

Rheumatol Int

journal_title

Rheumatology international

authors

Scherak O,Smolen JS,Mayr WR

doi

10.1007/BF00541190

subject

Has Abstract

pub_date

1983-01-01 00:00:00

pages

113-6

issue

3

eissn

0172-8172

issn

1437-160X

journal_volume

3

pub_type

杂志文章

相关文献

RHEUMATOLOGY INTERNATIONAL文献大全
  • Pattern of bone mineral density in idiopathic male osteoporosis.

    abstract：:The mechanisms of male idiopathic osteoporosis are little known. We evaluated bone mineral loss by dual-energy X-ray absorptiometry and determined its cortical or trabecular nature in a cohort of men with idiopathic osteoporosis with fractures. Thirty-nine men (mean age 60 ± 13 years), with negative investigations for...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-011-2076-7

    authors： Laroche M

    更新日期：2012-10-01 00:00:00

  • Successful treatment of nephrotic syndrome due to FMF amyloidosis with azathioprine: report of three Turkish cases.

    abstract：:Secondary amyloidosis is a well-known complication of certain familial Mediterranean fever (FMF). We presented three Turkish patients with FMF and biopsy proven amyloidosis. These patients were treated with colchicine 1.5 mg/day. They have experienced five to six peritonitis attacks with fever within 1 year. On admiss...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-006-0188-2

    authors： Sayarlioglu H,Erkoc R,Sayarlioglu M,Dogan E,Soyoral Y

    更新日期：2006-12-01 00:00:00

  • Cost per response for abatacept versus adalimumab in rheumatoid arthritis by ACPA subgroups in Germany, Italy, Spain, US and Canada.

    abstract：:Rheumatoid arthritis (RA) is a chronic inflammatory disorder leading to disability and reduced quality of life. Effective treatment with biologic DMARDs poses a significant economic burden. The Abatacept versus Adalimumab Comparison in Biologic-Naïve RA Subjects with Background Methotrexate (AMPLE) trial was a head-to...

    journal_title：Rheumatology international

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1007/s00296-017-3739-9

    authors： Weijers L,Baerwald C,Mennini FS,Rodríguez-Heredia JM,Bergman MJ,Choquette D,Herrmann KH,Attinà G,Nappi C,Merino SJ,Patel C,Mtibaa M,Foo J

    更新日期：2017-07-01 00:00:00

  • Anti-annexin II antibody is associated with thrombosis and/or pregnancy morbidity in antiphospholipid syndrome and systemic lupus erythematosus with thrombosis.

    abstract：:This study investigated the prevalence of antibody against annexin II (A2) in patients with antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE). It also explored the role of this antibody in thrombosis. Purified recombinant A2 was used in ELISA to measure the levels of IgG anti-A2 antibody in 101 AP...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-010-1379-4

    authors： Ao W,Zheng H,Chen XW,Shen Y,Yang CD

    更新日期：2011-07-01 00:00:00

  • Dilemma in management of hemorrhagic myositis in dermatomyositis.

    abstract：:Dermatomyositis (DM) is a rare inflammatory disorder affecting the muscle and skin. DM patients can present with spontaneous muscle hemorrhage, a potentially fatal complication. The best practice for management of hemorrhagic myositis in these patients remains unclear. Here we discuss the case of a patient who present...

    journal_title：Rheumatology international

    pub_type： 杂志文章,评审

    doi：10.1007/s00296-019-04501-7

    authors： Chandler JM,Kim YJ,Bauer JL,Wapnir IL

    更新日期：2020-02-01 00:00:00

  • Damage of cultured chondrocytes by hydrogen peroxide derived from polymorphonuclear leukocytes: a possible mechanism of cartilage degradation.

    abstract：:To study the mechanisms of chondrocyte damage, chondrocyte cytotoxicity as shown by chromium-51 release induced by polymorphonuclear leukocytes (PMNLs) was examined. PMNLs significantly enhanced chondrocyte cytotoxicity in the presence of phorbol dibutyrate. This chondrocyte damage was abolished by the addition of cat...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/BF00274933

    authors： Saura R,Matsubara T,Hirohata K,Itoh H

    更新日期：1992-01-01 00:00:00

  • Anti-cyclic citrullinated peptide antibodies as a discriminating marker between rheumatoid arthritis and chronic hepatitis C-related polyarthropathy.

    abstract：:Articular involvement is a frequent extrahepatic manifestation of hepatitis C virus (HCV) infection. The distinction between HCV-related polyarthropathy and true RA may be very difficult, especially with recent onset RA before articular damage and erosions develop. The objective of the study is to assess the diagnosti...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-009-1225-8

    authors： Ezzat WM,Raslan HM,Aly AA,Emara NA,El Menyawi MM,Edrees A

    更新日期：2011-01-01 00:00:00

  • P wave dispersion in patients with rheumatoid arthritis: its relation with clinical and echocardiographic parameters.

    abstract：:P wave dispersion (PWD) is a sign for the prediction of atrial fibrillation (AF). The aim of this study was to assess P wave dispersion and its relation with clinical and echocardiographic parameters in patients with rheumatoid arthritis (RA). Thirty RA patients (mean age 49 +/- 10 years) and 27 healthy controls (mean...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-007-0307-8

    authors： Guler H,Seyfeli E,Sahin G,Duru M,Akgul F,Saglam H,Yalcin F

    更新日期：2007-07-01 00:00:00

  • Comparison of an administrative algorithm for SLE disease severity to clinical SLE Disease Activity Index scores.

    abstract：:Systemic lupus erythematosus (SLE) severity, reflecting both disease intensity and duration, is heterogeneous making it challenging to study in administrative databases where severity may confound or mediate associations with outcomes. Garris et al. developed an administrative claims-based algorithm employing claims o...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-019-04477-4

    authors： Speyer CB,Li D,Guan H,Yoshida K,Stevens E,Jorge AM,Everett BM,Feldman CH,Costenbader KH

    更新日期：2020-02-01 00:00:00

  • Male gender results in more severe lupus nephritis.

    abstract：:Gender may produce different characteristics in the manifestation of systemic lupus erythematosus (SLE). The present study investigated the influence of gender on clinical, laboratory, autoantibodies and histopathological classes of lupus nephritis (LN). As much as 81 patients diagnosed with SLE (ACR criteria) and act...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-009-1151-9

    authors： de Carvalho JF,do Nascimento AP,Testagrossa LA,Barros RT,Bonfá E

    更新日期：2010-08-01 00:00:00

  • Brucellosis as a rare cause of olecranon bursitis: case-based review.

    abstract：:A 51-year-old man shepherd presented with mild pain and swelling of the right posterior aspect of his right elbow. In ultrasonography, the affected bursal space had swelling and effusion. Moreover, the aspiration of the affected bursa revealed an inflammatory profile. Brucella melitensis was detected in aspirated flui...

    journal_title：Rheumatology international

    pub_type： 杂志文章,评审

    doi：10.1007/s00296-019-04414-5

    authors： Esmaeilnejad-Ganji SM,Roushan MRH,Ebrahimpour S,Babazadeh A

    更新日期：2019-12-01 00:00:00

  • Parenchymal neuro-Behçet disease with erectile dysfunction and micturition disturbances: case report and literature review.

    abstract：:Parenchymal neuro-Behçet disease (NBD) is a serious clinic condition with a sub-acute or chronic disease course that results in incapability through pyramidal tract involvement. Though well-known consequences can deter a patient's life, both urinary symptoms and sexual dysfunction are underestimated complications of N...

    journal_title：Rheumatology international

    pub_type： 杂志文章,评审

    doi：10.1007/s00296-017-3858-3

    authors： Taylan A,Birlik M

    更新日期：2018-01-01 00:00:00

  • OPG inhibits gene expression of RANK and CAII in mouse osteoclast-like cell.

    abstract：:This study was designed to determine the effects of the osteoprotegerin (OPG) on the mRNA expression of carbonic anhydrase II (CAII) and the receptor activator of NF-κB (RANK) in mouse osteoclast-like cells. Marrow cells were harvested from femora and tibiae of mouse and cultured in 6-well chamber slides. After 1 day ...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-011-2338-4

    authors： Chen J,He JQ,Zhen SY,Huang LQ

    更新日期：2012-12-01 00:00:00

  • Liver enzyme abnormalities in systemic lupus erythematosus: a focus on toxic hepatitis.

    abstract：:Although subclinical liver disease is common in systemic lupus erythematosus (SLE), strikingly high levels of liver enzymes are rare. Our aim was to determine the cause of high levels of liver enzymes in lupus patients, particularly in patients diagnosed with toxic hepatitis. We performed a retrospective chart review ...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-009-1237-4

    authors： Her M,Lee Y,Jung E,Kim T,Kim D

    更新日期：2011-01-01 00:00:00

  • Human papillomavirus and chlamydia trachomatis infections in rheumatoid arthritis under anti-TNF therapy: an observational study.

    abstract：:The objective of this study was to evaluate human papillomavirus (HPV) and Chlamydia trachomatis (CT) infections in RA patients pre- and post-TNF blocker. Fifty female RA patients (ACR criteria), who were eligible to anti-TNF therapy [n = 50 at baseline (BL) and n = 45 after 6 months of treatment (6 M)], and 50 age-ma...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-014-3157-1

    authors： Waisberg MG,Ribeiro AC,Candido WM,Medeiros PB,Matsuzaki CN,Beldi MC,Tacla M,Caiaffa-Filho HH,Bonfa E,Silva CA

    更新日期：2015-03-01 00:00:00

  • Quantification of regulatory T cells in peripheral blood of patients with systemic lupus erythematosus.

    abstract：:Regulatory T cells (Tregs) are supposed to stop immune responses in the course of immune activation. However, chronic activation of immune system in systemic lupus erythematosus (SLE) and many other autoreactive disorders are evidence of malfunction of this system. Therefore, it is plausible to quantify presence of th...

    journal_title：Rheumatology international

    pub_type： 杂志文章,随机对照试验

    doi：10.1007/s00296-010-1427-0

    authors： Habibagahi M,Habibagahi Z,Jaberipour M,Aghdashi A

    更新日期：2011-09-01 00:00:00

  • A confusing case: pulmonary lesions including cavities, isolated left heart endocarditis and inferior vena cava thrombosis in a patient with perforated diverticulitis.

    abstract：:There are numerous causes of pulmonary cavitary lesions as infection (bacterial, parasitic and invasive fungal), Wegener granulomatosis (WG) and other vasculitis, sarcoidosis, malignancy, septic thromboembolism, airways disease (cystic bronchiectasis and bullae), pneumatoceles and traumatic parenchymal laceration. Her...

    journal_title：Rheumatology international

    pub_type： 信件

    doi：10.1007/s00296-012-2424-2

    authors： Işik M,Çinar E,Cemal Kizilarslanoğlu M,Özbek E,Etgül S,Kiraz S

    更新日期：2013-08-01 00:00:00

  • Health-related quality of life (Nottingham Health Profile) in knee osteoarthritis: correlation with clinical variables and self-reported disability.

    abstract：:The aims of this study were to assess the health-related quality of life (HRQoL) in patients with knee osteoarthritis (OA) using the Nottingham Health Profile (NHP) and to determine its relationships with conventional clinical measures and self-reported disability. One hundred and forty patients with knee OA (104 fema...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-009-1195-x

    authors： Yildiz N,Topuz O,Gungen GO,Deniz S,Alkan H,Ardic F

    更新日期：2010-11-01 00:00:00

  • Microscopic polyangiitis histologically confirmed by biopsy from nasal cavity and paranasal sinuses: a case report.

    abstract：:Microscopic polyangiitis (MPA) is a systemic necrotizing vasculitis affecting small vessels without necrotizing granulomatous inflammation and is commonly associated with necrotizing glomerulonephritis. Diagnosis is based on typical clinical features, the presence of antimyeloperoxidase-antineutrophil cytoplasmic anti...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-006-0127-2

    authors： Kokan N,Hosomi Y,Inamoto S,Ohnishi K,Tanimoto H,Nibu K

    更新日期：2006-08-01 00:00:00

  • The comparison of ultrasonographic and scintigraphic findings of early arthritis in revealing rheumatoid arthritis according to criteria of American College of Rheumatology.

    abstract：:We aimed to investigate the diagnostic significance of high frequency ultrasonography (USG), comparing the findings in USG, bone scintigraphy and clinical stuation. Fifty-one patients who had early symptoms of inflammatory arthritis, but not fulfilling the ACR diagnostic criteria for rheumatoid arthritis (RA) were inc...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-008-0765-7

    authors： Ozgul A,Yasar E,Arslan N,Balaban B,Taskaynatan MA,Tezel K,Baklaci K,Ozgüven MA,Kalyon TA

    更新日期：2009-05-01 00:00:00

  • Microscopic polyangiitis complicated with bilateral brachial plexopathy: a case report and review of the literature.

    abstract：:Microscopic polyangiitis is a small-vessel necrotizing vasculitis associated with anti-neutrophil cytoplasmic antibodies and presents itself with glomerulonephritis and hemorrhagic pulmonary capillaritis. Peripheral nervous system involvement is common in anti-neutrophil cytoplasmic antibodies-associated vasculitis, b...

    journal_title：Rheumatology international

    pub_type： 杂志文章,评审

    doi：10.1007/s00296-016-3424-4

    authors： Naseri Alavi SA,Meshkini M,Pourlak T,Khabbazi A

    更新日期：2016-07-01 00:00:00

  • Prevalence of dermatophytosis in patients with rheumatoid arthritis.

    abstract：OBJECTIVE:The prevalence of dermatophytic infections in rheumatoid arthritis is unknown. This study investigated the prevalence of dermatophytosis in patients with rheumatoid arthritis and the relationship between sulfasalazine, low-dose methotrexate and steroid therapy. METHODS:We examined 53 consecutive patients wit...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-002-0238-3

    authors： Bicer A,Tursen U,Cimen OB,Kaya TI,Ozisik S,Ikizoglu G,Erdogan C

    更新日期：2003-01-01 00:00:00

  • DNA synthesis in CD4- and CD8-positive cells in synovial fluid of patients with reactive and rheumatoid arthritis.

    abstract：:The occurrence of MHC class I antigens and microbial antigens derived from the triggering infection of the diseased joints in reactive arthritis (ReA) seems to set the stage for local immune activation. In this report activated lymphocytes are demonstrated by using an avidin-biotin-peroxidase complex (ABC) method comb...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/BF00270983

    authors： Nordström DC

    更新日期：1989-01-01 00:00:00

  • Determinants of health-related quality of life impairment in Egyptian children and adolescents with juvenile idiopathic arthritis: Sharkia Governorate.

    abstract：:The aim of this study was to identify the possible determinants of impaired health-related quality of life (HRQOL) in Egyptian children and adolescents with juvenile idiopathic arthritis (JIA). Fifty-eight consecutive patients of JIA aged from 8 to 18 years underwent assessment of socio-economic and demographic charac...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-014-2950-1

    authors： Abdul-Sattar AB,Elewa EA,El-Shahawy Eel-D,Waly EH

    更新日期：2014-08-01 00:00:00

  • Mitochondrial DNA haplogroups modulate the radiographic progression of Spanish patients with osteoarthritis.

    abstract：:Not all patients with osteoarthritis (OA) show the same disease progression, as some of them remain relatively stable over time, while others progress to severe structural deterioration of the joint. In this sense, the main goal of both genetic and protein biomarkers in OA is to predict not only the risk of OA at an e...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-014-3104-1

    authors： Soto-Hermida A,Fernández-Moreno M,Pértega-Díaz S,Oreiro N,Fernández-López C,Blanco FJ,Rego-Pérez I

    更新日期：2015-02-01 00:00:00

  • Validation of an adapted arabic version of fibromyalgia syndrome impact questionnaire.

    abstract：:Fibromyalgia (FM) is the most common chronic pain syndrome encountered in medical practice, affecting females more than males, and the estimated prevalence of FM in Egypt is 1.3 %. The aim was to translate and adapt the Fibromyalgia Impact Questionnaire (FIQ) into Arabic and assess reliability and validity. The Arabic...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-013-2779-z

    authors： El-Naby MA,Hefny MA,Fahim AE,Awadalla MA

    更新日期：2013-10-01 00:00:00

  • Meningitis in mixed connective tissue disease complicated by herpes virus infection: case report.

    abstract：:The authors report a rare case of a female patient diagnosed with mixed connective tissue disease (MCTD). After a few years in remission, the patient acquired herpes zoster infection followed by a disease flare. Disease activity was accompanied by the development of meningitis. To determine whether the meningitis was ...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-004-0440-6

    authors： Bodolay E,Diószeghy P,Demeter J,Bányai A,Csipö I,Szegedi G,Szekanecz Z

    更新日期：2004-11-01 00:00:00

  • Atrioventricular conduction time in rheumatoid arthritis.

    abstract：:The atrioventricular conduction time (P-R interval) was determined in 189 women and 90 men with rheumatoid arthritis (RA). Only three women and one man were found to have pathological prolongation of the P-R interval. However, a significant prolongation of the P-R interval, within normal range, was seen in women with ...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/BF00541337

    authors： Jurik AG,Møller P

    更新日期：1985-01-01 00:00:00

  • Effect of anti-TNF treatment on sleep problems in ankylosing spondylitis.

    abstract：:Sleep disturbances and problems are increased in ankylosing spondylitis (AS). But much is not known in a quantitative way about sleep problems and effect of treatments on AS. This study is aimed first, to investigate sleep disturbances in AS and secondly, to evaluate the effects of anti-TNF treatment on SD in AS. One ...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/s00296-011-1907-x

    authors： Karadağ O,Nakas D,Kalyoncu U,Akdoğan A,Kiraz S,Ertenli I

    更新日期：2012-07-01 00:00:00

  • Enzyme-linked immunosorbent assays for antibodies to poly(A), poly dAT and histones: possibly useful tools for the evaluation of prognosis and disease activity in systemic lupus erythematosus.

    abstract：:In a prospective study 222 sera from 56 patients with systemic lupus erythematosus (SLE) were tested for antibodies to poly(A), poly dAT and histones using enzyme-linked immunosorbent assay (ELISA). Patients with active disease had significantly more often antibodies to poly(A), poly dAT and histones than patients wit...

    journal_title：Rheumatology international

    pub_type： 杂志文章

    doi：10.1007/BF00541200

    authors： Helve T,Gripenberg M,Kurki P,Teppo AM,Wegelius O

    更新日期：1984-01-01 00:00:00