Abstract:
:Adult-onset Still's disease (AOSD) is a systemic inflammatory disease in which a variety of thrombotic events may occur. However, to our knowledge, portal vein thrombosis (PVT), a potential cause of gastrointestinal bleeding, has not been described in the English literature. A previously well 47-year-old man diagnosed with AOSD showed a transient increase in serum transaminase level. A careful observation led to a prompt discovery of a re-increase in serum transaminase level and PVT that involved an entire left portal vein plus parts of supramesenteric vein. PVT resolved completely in 6 months, and the patient remained well for at least 1 year receiving anticoagulants plus an immunosuppressant that selectively inhibits guanosine monophosphate synthesis in the purine metabolism pathway. Thrombotic events, if not lethal, deteriorate the quality of life in AOSD patients. This report illustrates the spectrum of AOSD and underlines the need to include PVT in differential diagnosis if serum liver enzyme levels fluctuate.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Morita H,Nishiwaki H,Nagayama Y,Yoshimura Adoi
10.1007/s00296-009-0894-7subject
Has Abstractpub_date
2009-10-01 00:00:00pages
1515-8issue
12eissn
0172-8172issn
1437-160Xjournal_volume
29pub_type
杂志文章,评审abstract::To determine the possible diagnostic and prognostic value of cartilage biomarkers in early-stage progressive and nonprogressive knee osteoarthritis (OA) in a population-based cohort of middle-aged subjects with chronic knee pain. Design tibiofemoral (TF) and patellofemoral (PF) radiographs were graded in 128 subjects ...
journal_title:Rheumatology international
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journal_title:Rheumatology international
pub_type: 杂志文章,多中心研究
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journal_title:Rheumatology international
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00290246
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journal_title:Rheumatology international
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journal_title:Rheumatology international
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journal_title:Rheumatology international
pub_type: 杂志文章,评审
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journal_title:Rheumatology international
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0540-9
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journal_title:Rheumatology international
pub_type: 杂志文章,评审
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journal_title:Rheumatology international
pub_type: 信件
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-007-0333-6
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-0920-9
更新日期:2009-11-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-006-0270-9
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journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-019-04414-5
更新日期:2019-12-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0565-0
更新日期:2008-08-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-012-2500-7
更新日期:2013-05-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-011-2162-x
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journal_title:Rheumatology international
pub_type: 杂志文章,评审
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journal_title:Rheumatology international
pub_type: 杂志文章
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-005-0057-4
更新日期:2006-03-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-013-2835-8
更新日期:2013-12-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-003-0358-4
更新日期:2004-07-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-014-3016-0
更新日期:2014-12-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-014-3079-y
更新日期:2015-01-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-006-0269-2
更新日期:2007-02-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-020-04679-1
更新日期:2021-02-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s002960100108
更新日期:2001-07-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-016-3541-0
更新日期:2017-01-01 00:00:00