Levels of soluble receptors for tumor necrosis factor type I and type II in paired synovial fluids of arthritis patients.

Abstract:

:The objective of this study was to determine whether levels of soluble receptors for tumor necrosis factor type I and type II (sTNF-RI and sTNF-RII) as measured in paired synovial fluids (SF) of arthritis patients are associated with clinical or laboratory parameters of local inflammation. sTNF-RI and -RII were measured by ELISA. We found that sTNF-RI and -RII did not correlate with activity of local inflammation. sTNF-RI levels correlated with sTNF-RII concentrations. We concluded that sTNF-RI and -II did not represent markers for local disease activity in arthritis patients.

journal_name

Rheumatol Int

authors

Miltenburg AM,Aderka D,van Laar JM,Wallach D,Breedveld FC

doi

10.1007/BF00290299

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

117-9

issue

3

eissn

0172-8172

issn

1437-160X

journal_volume

13

pub_type

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