Abstract:
:Cardiovascular disease (CVD) morbidity and mortality is highly prevalent in patients with rheumatoid arthritis (RA) with debilitating effects for the individual as well as significant healthcare impact. Current evidence demonstrates that engaging in aerobic and resistance exercise (i.e. structured physical activity) can significantly improve patient-reported and clinical index-assessed outcomes in RA. In addition to this, engagement in exercise programmes improves, in a dose-dependent manner, the risk of developing CVD as well as CVD symptoms and outcomes. The present narrative review uses evidence from systematic reviews and meta-analyses as well as controlled trials, to synthesize the current state-of-the-art on the potential effects of aerobic and resistance exercise on CVD risk factors as well as on cardiac and vascular function and structure in people with RA. Where there is a lack of evidence in RA to explain potential mechanisms, relevant studies from the general population are also discussed and linked to RA.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Metsios GS,Moe RH,van der Esch M,van Zanten JJCSV,Fenton SAM,Koutedakis Y,Vitalis P,Kennedy N,Brodin N,Bostrom C,Swinnen TW,Tzika K,Niedermann K,Nikiphorou E,Fragoulis GE,Vlieland TPVM,Van den Ende CHM,Kitas GD,IMPACTdoi
10.1007/s00296-019-04483-6subject
Has Abstractpub_date
2020-03-01 00:00:00pages
347-357issue
3eissn
0172-8172issn
1437-160Xpii
10.1007/s00296-019-04483-6journal_volume
40pub_type
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