The effects of exercise on cardiovascular disease risk factors and cardiovascular physiology in rheumatoid arthritis.

Abstract:

:Cardiovascular disease (CVD) morbidity and mortality is highly prevalent in patients with rheumatoid arthritis (RA) with debilitating effects for the individual as well as significant healthcare impact. Current evidence demonstrates that engaging in aerobic and resistance exercise (i.e. structured physical activity) can significantly improve patient-reported and clinical index-assessed outcomes in RA. In addition to this, engagement in exercise programmes improves, in a dose-dependent manner, the risk of developing CVD as well as CVD symptoms and outcomes. The present narrative review uses evidence from systematic reviews and meta-analyses as well as controlled trials, to synthesize the current state-of-the-art on the potential effects of aerobic and resistance exercise on CVD risk factors as well as on cardiac and vascular function and structure in people with RA. Where there is a lack of evidence in RA to explain potential mechanisms, relevant studies from the general population are also discussed and linked to RA.

journal_name

Rheumatol Int

authors

Metsios GS,Moe RH,van der Esch M,van Zanten JJCSV,Fenton SAM,Koutedakis Y,Vitalis P,Kennedy N,Brodin N,Bostrom C,Swinnen TW,Tzika K,Niedermann K,Nikiphorou E,Fragoulis GE,Vlieland TPVM,Van den Ende CHM,Kitas GD,IMPACT

doi

10.1007/s00296-019-04483-6

subject

Has Abstract

pub_date

2020-03-01 00:00:00

pages

347-357

issue

3

eissn

0172-8172

issn

1437-160X

pii

10.1007/s00296-019-04483-6

journal_volume

40

pub_type

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