Abstract:
:Citrulline antibody, nowadays, is a new item which has been the center of attention due to its much more specificity to diagnose RA. The aim of the present study was to evaluate the efficacy and accuracy of anti-citrulline antibody test in RA diagnosis among hospitalized patients in Iran. Through a case-control study, we tried to calculate the accuracy of anti-cyclic citrullinated peptide antibody (anti-CCP) test used in the diagnosis of RA enrolling 200 participants divided into two groups of the patients with RA, on the one hand, and other diseases, on the other. Anti-CCP was measured by ELISA technique through which titers more than 15 were defined as high titer. Of all the studied population, 81 (81 %) were in active phase of RA, which had anti-CCP >15 U/ml, while only 25 controls (25 %) experienced these levels. The average anti-CCP was 144 U/ml in cases and 16.05 U/ml in controls with a P value <0.001, which confirmed significant difference between the two. Considering different comments on this matter besides our findings in the present research, we offer a combination of anti-citrulline antibody test rather than anti-CCP and RF to get the best results in RA diagnosis, discrimination and prognosis because of 97 % specificity.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Abolghasemi S,Gitipour A,Morteza Adoi
10.1007/s00296-012-2469-2subject
Has Abstractpub_date
2013-04-01 00:00:00pages
1027-30issue
4eissn
0172-8172issn
1437-160Xjournal_volume
33pub_type
杂志文章abstract::Isoform 4 of the human peptidylarginine deiminase (hPAD4) enzyme may be responsible for the citrullination of antigens in rheumatoid arthritis (RA) and has been shown to be itself the target of disease-specific autoantibodies. Here, we have tested whether the level of serum anti-hPAD4 antibodies in RA patients is stab...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1765-y
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:Axillary lymph nodes (ALNs) are often seen on chest computed tomography (CT) in rheumatoid arthritis (RA) patients. Early reports described lymphadenopathy as one of the systemic manifestations rather than regional lymphadenopathy secondary to drainage from the affected joints. Subsequently, the importance o...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-018-3992-6
更新日期:2018-06-01 00:00:00
abstract::Macrophagic myofascitis (MMF) is an unusual inflammatory myopathy characterized by muscle infiltration by macrophages and lymphocytes. Here, we describe a case of MMF which is associated with rheumatoid arthritis. A 53-year-old Japanese rheumatoid arthritis (RA) patient presented with focal tenderness of lower extremi...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-1015-3
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abstract::The diagnosis of Kawasaki disease (KD), a common pediatric vasculitis, is based solely on clinical criteria. There is a need for a robust laboratory marker that can help differentiate KD from other acute, febrile, childhood illnesses and also to predict cardiac involvement. We conducted a cross-sectional study of 25 c...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-016-3430-6
更新日期:2016-04-01 00:00:00
abstract::The objective of this study was to compare rheumatoid arthritis (RA) disease activity and patient-reported outcomes (PROs) in a national sample of patients with RA with/without Sjögren's syndrome (SS). Adults with RA from a large observational US registry (Corrona RA) with known SS status between 22 April 2010 and 31 ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-020-04602-8
更新日期:2020-08-01 00:00:00
abstract::Patients with rheumatoid arthritis (RA) have bone loss to various degrees at different skeletal sites. The subregional bone mineral density (BMD) of the hand and the correlation of BMD to other regional bone losses, parameters of inflammation or bone resorption was evaluated in 421 patients with RA and controls. RA pa...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0638-0
更新日期:2008-11-01 00:00:00
abstract::Schistosomiasis or bilharzia is a parasitic disease found in tropical countries. Most infections are subclinical but may progress to chronic form characterized most frequently by the presence of liver involvement and portal hypertension. We report a patient that presented chronic polyarthritis with positive rheumatoid...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1562-7
更新日期:2013-05-01 00:00:00
abstract::IgM, IgG and IgA class antibodies against Yersinia, Salmonella, Campylobacter and Borrelia were determined by enzyme-linked immunosorbent assay (ELISA) in a group of 340 unselected patients with a recent inflammatory joint disease. The control group consisted of 340 and 100 healthy blood donors using Borrelia-ELISA an...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF02274884
更新日期:1991-01-01 00:00:00
abstract::In a randomized multicenter, double-blind, double-dummy, parallel group study a comparison of the efficacy and safety of 1 microg alfacalcidol to 880 IU vitamin D plus calcium carbonate (1 g calcium) once daily per os was performed on 148 postmenopausal osteoporotic Caucasian patients with normal vitamin D serum level...
journal_title:Rheumatology international
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2006-03-01 00:00:00
abstract::There are no standardized bedside assessments for subtyping patients with osteoarthritis (OA) based on pain mechanisms. Thus, we developed a bedside sensory testing kit (BSTK) to classify OA patients based on sensory profiles potentially indicative of pain mechanism. After usability and informal reliability testing (n...
journal_title:Rheumatology international
pub_type: 杂志文章
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更新日期:2015-06-01 00:00:00
abstract::Familial Mediterranean fever (FMF) is an autosomal recessive, inherited autoinflammatory disease characterized by recurrent, self-limited attacks of fever and inflammation of serosal surfaces. There is an explosion of the data regarding inflammatory markers in FMF and clinical effects of chronic inflammation on the di...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-011-2281-4
更新日期:2012-12-01 00:00:00
abstract::The aims of this study were to assess the health-related quality of life (HRQoL) in patients with knee osteoarthritis (OA) using the Nottingham Health Profile (NHP) and to determine its relationships with conventional clinical measures and self-reported disability. One hundred and forty patients with knee OA (104 fema...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-1195-x
更新日期:2010-11-01 00:00:00
abstract::The case of an apparent healthy woman who developed recurrent preeclampsia with antiphospholipid antibodies and evolved towards systemic lupus erythematosus during her last pregnancy is presented. The diagnostic dilemma between lupus renal flare and toxemia is discussed. The potential role of immunological alterations...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-002-0210-2
更新日期:2002-07-01 00:00:00
abstract::We have recently reported on two cases of scleroderma patients with ANCA-associated vasculitis for the first time in Korea. In order to explore the nature of this disease combination, we pooled together all the previously known cases and statistically analyzed them. Out of the 50 selected cases, survival analysis was ...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-005-0011-5
更新日期:2006-03-01 00:00:00
abstract::Osteoporosis has become an increasingly recognized complication among patients with chronic liver disease (CLD). The aim of the present study was to assess the prevalence and risk factors of osteoporosis in patients with CLD (primary biliary cirrhosis and chronic viral hepatitis B or C patients) in comparison with a g...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-1071-8
更新日期:2010-05-01 00:00:00
abstract::The aim of our study was to compare the significance of risk factors for osteoporosis according to gender and menopausal state in patients with rheumatoid arthritis (RA). Bone mineral density (dual X-ray absorptiometry), cumulative glucocorticoid dose, age, disease duration, body mass index (BMI) and parameters of dis...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0576-x
更新日期:2008-09-01 00:00:00
abstract::Autoimmune diseases (AID) are caused by the loss of immunological tolerance against self-antigens. The deoxyribonuclease I (DNASE1) gene seems to participate in the genetic susceptibility of some AID. In fact, two mutations were reported among systemic lupus erythematosus (SLE) patients from Japan and Spain (the 172 A...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-0917-4
更新日期:2009-11-01 00:00:00
abstract::The aim of this systematic review was to evaluate the evidence from randomised controlled trials (RCTs) evaluating the effectiveness of interactive digital interventions (IDIs) for physical activity (PA) and health related quality of life (HRQoL) in people with Inflammatory Arthritis [rheumatoid arthritis (RA), juveni...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-018-4010-8
更新日期:2018-09-01 00:00:00
abstract::Patients with rheumatoid arthritis (RA) are at increased risk of low bone density and fractures. This study identifies predictors of initiation of dual energy X-ray absorptiometry (DXA) testing in RA. We identified RA patients from the CORRONA registry with >or=1 year follow-up without reported DXA at study entry. The...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0804-4
更新日期:2009-06-01 00:00:00
abstract::Chronic inflammation starting early in life and continuing into adulthood may predispose children with Juvenile Idiopathic Arthritis (JIA) to cardiovascular (CV) complications. To compare non-invasive CV risk markers- left ventricular mass index (LVMi), brachial artery flow mediated dilatation (FMD) and carotid artery...
journal_title:Rheumatology international
pub_type: 杂志文章
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更新日期:2021-02-01 00:00:00
abstract::We assess the usefulness of 99mTc-pertechnetate hand perfusion scintigraphy in patients with Raynaud's phenomenon (RP). The study population consisted of 18 patients with primary RP, 25 patients with secondary RP within systemic sclerosis (SSc), and ten healthy individuals. Gamma camera dynamic first-pass study during...
journal_title:Rheumatology international
pub_type: 杂志文章
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更新日期:2016-12-01 00:00:00
abstract::It is known that patients with rheumatoid arthritis (RA) have an increased risk for non-Hodgkin's lymphomas in comparison with the general population. Although increased risk of lymphoma is attributed to the disease activity, the drugs used in the therapy of RA may also cause increased risk of malignancy. Herein, we r...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-1184-0
更新日期:2011-04-01 00:00:00
abstract::To evaluate the correlation between measurements of antinuclear antibodies serum levels by enzyme immunoassay (ANA-EIA), and the degree of systemic lupus erythematosus disease activity. To retest the performance of the test compared to measurement of antinuclear antibodies by immunofluorescence (ANA-IIF). Eighty-five ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-007-0324-7
更新日期:2007-08-01 00:00:00
abstract:KEY MESSAGES:No difference between both hands was observed for clinical and radiographical presentations in EHOA patients. A bilateral and symmetrical relationship was found between hand joints. HIGHLIGHTS:EHOA have symmetrical distribution and specific association in structural lesions. This study aims to analyse the...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-020-04784-1
更新日期:2021-01-27 00:00:00
abstract::The objective of this study is to investigate the clinical markers of life-threatening Pneumocystis pneumonia (PCP) in patients with collagen vascular diseases (CVD). The patients who contracted Pneumocystis jeroveccii were retrospectively selected from our medical charts and conditions related to the patients' death ...
journal_title:Rheumatology international
pub_type: 杂志文章
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abstract::The objective of the study was to assess the ESSDAI index characteristics in the SJÖGRENSER cohort (Spanish Rheumatology Association's registry of patients with Primary Sjögren Syndrome [PSS]). SJÖGRENSER is a prospective multicentric study on a cohort of Spanish patients with PSS who meet the 2002 American-European c...
journal_title:Rheumatology international
pub_type: 杂志文章
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更新日期:2019-06-01 00:00:00
abstract::The objective of this study was to determine whether levels of soluble receptors for tumor necrosis factor type I and type II (sTNF-RI and sTNF-RII) as measured in paired synovial fluids (SF) of arthritis patients are associated with clinical or laboratory parameters of local inflammation. sTNF-RI and -RII were measur...
journal_title:Rheumatology international
pub_type: 杂志文章
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更新日期:1993-01-01 00:00:00
abstract::Uveitis may represent an opportunity to diagnose spondyloarthropathies (SpA) earlier and influence treatment decisions. We describe the percentage of acute anterior uveitis (AAU) in a diverse group of SpA patients seen at one academic setting and compare demographic and clinical characteristics according to the presen...
journal_title:Rheumatology international
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更新日期:2019-09-01 00:00:00
abstract::Several studies of rheumatoid arthritis (RA) incidence and prevalence indicate that occurrence of the disease varies significantly among different populations. We aimed to estimate the prevalence and incidence of RA in South Korea. We used Korean National Health Insurance (NHI) claims data to estimate the prevalence o...
journal_title:Rheumatology international
pub_type: 杂志文章
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更新日期:2013-06-01 00:00:00
abstract::In recent years, scientific efforts on the topic "gout" have focused on pathogenetic aspects. This has opened new strategies of anti-inflammatory therapy and has improved urate-lowering therapy. So far, a scientometric analysis of the topic "gout" has not been generated despite an increased need for it in times of mod...
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