Investigation of the association between Rho/Rho-kinase gene polymorphisms and systemic sclerosis.

abstract：:Fibromyalgia is a multi-factorial illness primarily characterised by widespread chronic pain and fatigue, with several symptoms and associated conditions. Due to a lack of clinical awareness and an absence of objective diagnostic measures, fibromyalgia patients often engage with online health information. The aim is t...

journal_title：Rheumatology international

authors： Basavakumar D,Flegg M,Eccles J,Ghezzi P

更新日期：2019-04-01 00:00:00

abstract：:The purpose of the present study was to evaluate the toxicity and tolerability of methotrexate (MTX)/gold (G; group 1) combination therapy as compared to other MTX combinations [MTX with hydroxychloroquine (HCQ; group 2), MTX with sulphasalazine (SASP; group 3) and MTX with minocycline (MNC; group 4)]. The hospital re...

journal_title：Rheumatology international

authors： Elkayam O,Yaron M,Zhukovsky G,Segal R,Caspi D

更新日期：1997-01-01 00:00:00

abstract：:Systemic immune defects might reflect severely dysregulated control of chronic inflammation related to disease progression. Th17/Treg cell imbalance has been demonstrated to be involved in rheumatoid arthritis (RA) pathogenesis. Despite controversial results, a growing anti-inflammatory role in this process has been r...

journal_title：Rheumatology international

authors： Kosmaczewska A,Swierkot J,Ciszak L,Szteblich A,Chrobak A,Karabon L,Partyka A,Szechinski J,Wiland P,Frydecka I

更新日期：2014-02-01 00:00:00

abstract：:Giant cell arteritis (GCA) is the most common systemic vasculitis affecting people over 50 years. This disease is a diagnostic challenge with a range of clinical symptoms and findings due to different affected vessels. Because of this, the initial diagnosis can be tricky, and some of the patients present at first time...

journal_title：Rheumatology international

authors： Husein-Elahmed H,Callejas-Rubio JL,Rios-Fernández R,Ortego-Centeno N

更新日期：2012-03-01 00:00:00

abstract：UNLABELLED:The objective of this study is to provide a critical overview of available instruments to assess impairments in patients with rheumatic disorders, and to recommend reliable and valid instruments for use in allied health care and rehabilitation medicine. A computer-aided literature search (1982-2004) in sever...

journal_title：Rheumatology international

authors： Swinkels RA,Bouter LM,Oostendorp RA,van den Ende CH

更新日期：2005-09-01 00:00:00

abstract：:Dermatomyositis (DM) is a rare inflammatory disorder affecting the muscle and skin. DM patients can present with spontaneous muscle hemorrhage, a potentially fatal complication. The best practice for management of hemorrhagic myositis in these patients remains unclear. Here we discuss the case of a patient who present...

journal_title：Rheumatology international

authors： Chandler JM,Kim YJ,Bauer JL,Wapnir IL

更新日期：2020-02-01 00:00:00

abstract：:To evaluate serum levels of IL6 in patients with Kawasaki disease and compare it with CRP, and to assess the role of these biomarkers in predicting coronary changes and resistance to the first-line therapy of this disease in a subset of Indian population. A single centre prospective observational study was conducted a...

journal_title：Rheumatology international

authors： Nandi A,Pal P,Basu S

更新日期：2019-10-01 00:00:00

abstract：:The aim of our study was to evaluate effectiveness of ultrasound treatment applied with exercise therapy in patients with ankylosing spondylitis. Fifty-two patients, who were diagnosed according to modified New York criteria, were aged 25-60, and have spine pain, were randomly assigned to two groups. Ultrasound (US) a...

journal_title：Rheumatology international

authors： Şilte Karamanlioğlu D,Aktas I,Ozkan FU,Kaysin M,Girgin N

更新日期：2016-05-01 00:00:00

abstract：:The objective of this study was to determine whether levels of soluble receptors for tumor necrosis factor type I and type II (sTNF-RI and sTNF-RII) as measured in paired synovial fluids (SF) of arthritis patients are associated with clinical or laboratory parameters of local inflammation. sTNF-RI and -RII were measur...

journal_title：Rheumatology international

authors： Miltenburg AM,Aderka D,van Laar JM,Wallach D,Breedveld FC

更新日期：1993-01-01 00:00:00

abstract：:Neurocognitive dysfunction and brain injury on magnetic resonance imaging (MRI) are common in patients with systemic lupus erythematosus (SLE) and are associated with increased morbidity and mortality. However, brain MRI is expensive, is restricted by payers, and requires high expertise. Neurocognitive assessment is a...

journal_title：Rheumatology international

authors： Roldan PC,Jung RE,Sibbitt WL,Qualls CR,Flores RA,Roldan CA

更新日期：2018-08-01 00:00:00

abstract：:Behçet's disease (BD) is a multi-system inflammatory disorder, in which cytokine balance is polarized to Th1. In this study, the cell surface molecule expression, Th1/Th2, inflammatory cytokine levels in blood, and synovial fluid of CD3(+) T lymphocytes in BD were investigated. The study group consisted of 10 BD, 10 a...

journal_title：Rheumatology international

authors： Aktas Cetin E,Cosan F,Kucuksezer UC,Bilgic S,Cagatay Y,Gul A,Deniz G

更新日期：2013-03-01 00:00:00

abstract：:The expressions of some terminal glycotopes of synovial immunoglobulins G, A, and M were analysed in relation to rheumatoid arthritis (RA) progression defined according to early and advanced radiological changes in patients' hands. The relative amounts of terminal monosaccharides were determined by lectin-immunoblotti...

journal_title：Rheumatology international

authors： Kratz EM,Borysewicz K,Katnik-Prastowska I

更新日期：2010-08-01 00:00:00

abstract：:Resveratrol (trans-3,4'-trihydroxystilbene), a natural phytoalexin, possesses anti-inflammatory, anti-proliferative, and immunomodulatory properties and has the potential for treating inflammatory disorders. The present study was designed to investigate the effects of resveratrol on TNF-α-induced inflammatory cytokine...

journal_title：Rheumatology international

authors： Tian J,Chen JW,Gao JS,Li L,Xie X

更新日期：2013-07-01 00:00:00

abstract：:The objective of this study was to compare rheumatoid arthritis (RA) disease activity and patient-reported outcomes (PROs) in a national sample of patients with RA with/without Sjögren's syndrome (SS). Adults with RA from a large observational US registry (Corrona RA) with known SS status between 22 April 2010 and 31 ...

journal_title：Rheumatology international

authors： Harrold LR,Shan Y,Rebello S,Kramer N,Connolly SE,Alemao E,Kelly S,Kremer JM,Rosenstein ED

更新日期：2020-08-01 00:00:00

abstract：:The aim of the study was the thermovisual comparison of mean temperature of hand surface changes after local cryotherapy with vapors of nitrogen (-160°C) and cold air (-30°C). Forty-seven patients with rheumatoid arthritis (39 women and 8 men; average age 56.2 ± 10.5 years) were included in the study. They had the app...

journal_title：Rheumatology international

authors： Korman P,Straburzyńska-Lupa A,Romanowski W,Trafarski A

更新日期：2012-10-01 00:00:00

abstract：:Sleep disturbances and problems are increased in ankylosing spondylitis (AS). But much is not known in a quantitative way about sleep problems and effect of treatments on AS. This study is aimed first, to investigate sleep disturbances in AS and secondly, to evaluate the effects of anti-TNF treatment on SD in AS. One ...

journal_title：Rheumatology international

authors： Karadağ O,Nakas D,Kalyoncu U,Akdoğan A,Kiraz S,Ertenli I

更新日期：2012-07-01 00:00:00

abstract：:Osteoporosis has become an increasingly recognized complication among patients with chronic liver disease (CLD). The aim of the present study was to assess the prevalence and risk factors of osteoporosis in patients with CLD (primary biliary cirrhosis and chronic viral hepatitis B or C patients) in comparison with a g...

journal_title：Rheumatology international

authors： Wariaghli G,Mounach A,Achemlal L,Benbaghdadi I,Aouragh A,Bezza A,El Maghraoui A

更新日期：2010-05-01 00:00:00

abstract：:A recent genome-wide association study revealed that there is an association between serum uric acid (SUA) levels and rs2544390, a common variant in low-density lipoprotein-related protein 2 (LRP2/Megalin) gene. Two other variants of LRP2, rs2229268 and rs3755166, are also found to have associations with dyslipidemia ...

journal_title：Rheumatology international

authors： Nakayama A,Matsuo H,Shimizu T,Takada Y,Nakamura T,Shimizu S,Chiba T,Sakiyama M,Naito M,Morita E,Ichida K,Shinomiya N

更新日期：2014-04-01 00:00:00

abstract：:Seronegative spondylarthropathies are disorders with the same predisposing antigen, namely HLA B27, a class I molecule of the HLA system. The mechanisms of the different diseases are unknown, and there is no proof of immune system participation. We have investigated patients with spondylarthropathies in order to searc...

journal_title：Rheumatology international

authors： Toussirot E,Lafforgue P,Boucraut J,Despieds P,Schiano A,Bernard D,Acquaviva PC

更新日期：1994-01-01 00:00:00

abstract：:The thiol status of patients with rheumatoid arthritis is significantly different from that of controls. Plasma thiol levels are lower, albumin thiol reactivity is altered and intracellular thiol levels measured after hemoglobin precipitation are increased. These variations correlate with other indices of disease seve...

journal_title：Rheumatology international

authors： Banford JC,Brown DH,Hazelton RA,McNeil CJ,Smith WE,Sturrock RD

更新日期：1982-01-01 00:00:00

abstract：OBJECTIVE:Recent studies revealed trisomy 7 as a chromosomal abnormality in non-neoplastic disorders such as rheumatoid arthritis (RA). In the present study, we investigated the presence of trisomy 7 in the synovial fluid cells of patients with RA using fluorescence in situ hybridisation (FISH) analysis. METHODS:Synov...

journal_title：Rheumatology international

authors： Tascioglu F,Durak B,Oner C,Artan S

更新日期：2005-10-01 00:00:00

abstract：:The aim of this study was to investigate the prevalence, predictors and radiological findings of primary Sjögren's syndrome (pSS)-associated lung involvement. This retrospective cohort study included 123 patients with demographic, clinical, laboratory and radiological data who were diagnosed with pSS. Lung involvement...

journal_title：Rheumatology international

authors： Yazisiz V,Arslan G,Ozbudak IH,Turker S,Erbasan F,Avci AB,Ozbudak O,Terzioglu E

更新日期：2010-08-01 00:00:00

abstract：:Anemia is common with connective tissue disorders, but pancytopenia is rare. We report a 22-year-old female who presented with menorrhagia, seizures, anemia, leukocytosis, thrombocytopenia, pericardial effusion, positive ANA, and evidence of vasculitis on CT head scan and was diagnosed with systemic lupus erythematosu...

journal_title：Rheumatology international

authors： Singh NP,Prakash A,Garg D,Makhija A,Pathania A,Prakash N,Kubba S,Agarwal SK

更新日期：2004-01-01 00:00:00

abstract：:We report a case of visceral leishmaniasis in a patient from northern Norway with psoriatic arthritis treated with a combination of etanercept and methotrexate. The patient resided extensively in southern Spain, a zone endemic for leishmania. ...

journal_title：Rheumatology international

authors： Besada E,Njålla RJ,Nossent JC

更新日期：2013-10-01 00:00:00

abstract：:Life expectancy in autoimmune rheumatic diseases (ARDs) remains lower compared to the general population, due to various comoborbidities. Cardiovascular disease (CVD) represents the main contributor to premature mortality. Conventional and biologic disease-modifying antirheumatic drugs (DMARDs) have considerably impro...

journal_title：Rheumatology international

authors： Mavrogeni SI,Sfikakis PP,Dimitroulas T,Koutsogeorgopoulou L,Katsifis G,Markousis-Mavrogenis G,Kolovou G,Kitas GD

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:The prevalence of dermatophytic infections in rheumatoid arthritis is unknown. This study investigated the prevalence of dermatophytosis in patients with rheumatoid arthritis and the relationship between sulfasalazine, low-dose methotrexate and steroid therapy. METHODS:We examined 53 consecutive patients wit...

journal_title：Rheumatology international

authors： Bicer A,Tursen U,Cimen OB,Kaya TI,Ozisik S,Ikizoglu G,Erdogan C

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:The aim was to evaluate the efficacy and safety of multiple infusions with achimeric, anti-tumor necrosis factor (TNF)alpha monoclonal antibody (infliximab) in patients with psoriatic arthritis (PsA) and psoriasis vulgaris. METHODS:Over 22 weeks, nine patients with both active psoriasis and PsA received five...

journal_title：Rheumatology international

authors： Cauza E,Spak M,Cauza K,Hanusch-Enserer U,Dunky A,Wagner E

更新日期：2002-11-01 00:00:00

abstract：:Several molecular epidemiological studies have been conducted in recent years to evaluate a possible association between the interferon regulatory factor 5 (IRF5) rs2004640 polymorphism and rheumatoid arthritis risk in diverse populations. However, the results remain conflicting rather than conclusive. Our aim was to ...

journal_title：Rheumatology international

authors： Jia X,Hu M,Lin Q,Ren H

更新日期：2013-11-01 00:00:00

abstract：:This prospective study aimed to determine the patient acceptable symptom state (PASS) cut-off for the patient reported outcome measure shoulder pain and disability index (SPADI), and evaluate predictors of PASS achievement following standard shoulder care. Patients with shoulder pain, referred for shoulder ultrasound ...

journal_title：Rheumatology international

authors： Tran G,Dube B,Kingsbury SR,Tennant A,Conaghan PG,Hensor EMA

更新日期：2020-04-01 00:00:00

abstract：:We describe a typical case of a patient with remitting seronegative symmetrical synovitis and pitting edema (RS(3)PE) syndrome. He underwent a successful clinical course monitored by serologic variables and radiographic methods. Serum levels of interleukin-6 (IL-6), vascular endothelial growth factor (VEGF), matrix me...

journal_title：Rheumatology international

authors： Kawashiri SY,Nakano M,Kawakami A,Eguchi K

更新日期：2010-11-01 00:00:00