Abstract:
:The purpose of this study was to compare quality of life health identifiers in patients with and without osteoarthritis (OA) while controlling for the potentially confounding variables of gender, age, race, education, and income. Data were obtained for comparison from the Behavioral Risk Factor Surveillance System (BRFSS) database. Patients with and without OA were analyzed for differences in exercise and activity level, report of physical and mental health, and joint-related symptoms. Over 37,000 individuals were included in the analysis, 6,172 of the participants reported a diagnosis of OA. Participants with a report of OA were more likely to identify problems in all categories except report of mental health. When the potentially confounding variables were controlled, individuals with OA were more likely to report mental health problems. These findings suggest that individuals with OA are more likely to report lower levels of quality of life even while controlling confounding variables.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Cook C,Pietrobon R,Hegedus Edoi
10.1007/s00296-006-0269-2subject
Has Abstractpub_date
2007-02-01 00:00:00pages
315-21issue
4eissn
0172-8172issn
1437-160Xjournal_volume
27pub_type
杂志文章abstract::The mechanisms of male idiopathic osteoporosis are little known. We evaluated bone mineral loss by dual-energy X-ray absorptiometry and determined its cortical or trabecular nature in a cohort of men with idiopathic osteoporosis with fractures. Thirty-nine men (mean age 60 ± 13 years), with negative investigations for...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-011-2076-7
更新日期:2012-10-01 00:00:00
abstract::Systemic lupus erythematosus (SLE) affects women of childbearing age. To optimize fetal and maternal outcomes, effective reproductive health counseling is crucial. To analyze the effectiveness of reproductive health counseling in women with SLE and identify gaps in patient educational needs. Cross-sectional study incl...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-020-04671-9
更新日期:2021-02-01 00:00:00
abstract::This study examines whether or not MBD4 polymorphism is a marker for rheumatoid arthritis (RA) susceptibility or severity for Chinese patients in Taiwan. This study included 193 patients with RA, while 190 unrelated healthy individuals living in Central Taiwan served as controls. The relationship between MBD4 polymorp...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1545-8
更新日期:2012-01-01 00:00:00
abstract::The occurrence of MHC class I antigens and microbial antigens derived from the triggering infection of the diseased joints in reactive arthritis (ReA) seems to set the stage for local immune activation. In this report activated lymphocytes are demonstrated by using an avidin-biotin-peroxidase complex (ABC) method comb...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00270983
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVE:Neprilysin (neutral endopeptidase, 3:4:24:11, CD10) (NEP) is a Zn metallopeptidase linked to controlling inflammation through the degradation of neuropeptides involved in neurogenic inflammation of chronic rheumatic diseases. The aim of our study was to evaluate circulating activity and cellular expression of...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-004-0447-z
更新日期:2005-06-01 00:00:00
abstract::Systemic sclerosis (SSc) is a disease characterized by inflammation, vascular abnormalities and fibrosis. The role of Rho/Rho-kinase pathway was demonstrated in the pathogenesis of fibrosis, inflammation and vascular abnormalities. This study was aimed to investigate the relation between SSc and Rho/Rho-kinase gene po...
journal_title:Rheumatology international
pub_type: 杂志文章,多中心研究
doi:10.1007/s00296-015-3400-4
更新日期:2016-03-01 00:00:00
abstract::Osteoarthritis (OA) has a strong genetic component, and experimental evidence suggests the involvement of the Wnt pathway in its pathogenesis. Hence, we explored the association of common single nucleotide polymorphisms (SNPs) related to the Wnt pathway with hip and knee OA. Seventy-eight SNPs were analyzed in 606 pat...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-013-2821-1
更新日期:2013-11-01 00:00:00
abstract::It is known that patients with rheumatoid arthritis (RA) have an increased risk for non-Hodgkin's lymphomas in comparison with the general population. Although increased risk of lymphoma is attributed to the disease activity, the drugs used in the therapy of RA may also cause increased risk of malignancy. Herein, we r...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-1184-0
更新日期:2011-04-01 00:00:00
abstract::We evaluated the frequency of secondary amyloidosis, associated clinical features, and outcomes in ankylosing spondylitis (AS) patients diagnosed in the last decade. The medical records of AS patients diagnosed at single academic medical center were reviewed for clinical evidence of amyloidosis. During routine follow-...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-012-2646-3
更新日期:2013-07-01 00:00:00
abstract::To evaluate the correlation between measurements of antinuclear antibodies serum levels by enzyme immunoassay (ANA-EIA), and the degree of systemic lupus erythematosus disease activity. To retest the performance of the test compared to measurement of antinuclear antibodies by immunofluorescence (ANA-IIF). Eighty-five ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-007-0324-7
更新日期:2007-08-01 00:00:00
abstract::The neutrophilic granule protein proteinase 3 (PR3) is the preferred target antigen of anti-neutrophil cytoplasmic antibodies (ANCA) found in the serum of patients with Wegener's granulomatosis, a systemic small-vessel vasculitis. Due to the lack of data concerning the murine homologue of human PR3, we assessed the ne...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1672-2
更新日期:2011-08-01 00:00:00
abstract::The aim of this study was to compare clinical symptoms, perceived health status, health resource use and psychosocial features in fibromyalgia (FM) patients at different health care levels. A total of 315 participants were recruited from primary care (PC) (n=101) and rheumatology settings (RS) (n=214). Subjects comple...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0818-y
更新日期:2009-08-01 00:00:00
abstract::The exact elucidation of skeletal and cartilagineous involvement in neonatal-onset multisystem inflammatory disease (NOMID) is still poorly known, and there are few data providing the long-term response to treatment with the available interleukin-1 inhibitors. We present here a 13-year-old boy with NOMID treated with ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1787-5
更新日期:2011-12-01 00:00:00
abstract::Fibrodysplasia ossificans progressiva (FOP) is a rare but extremely disabling genetic disease of the skeletal system. This disease is characterized by progression of heterotopic ossification within skeletal muscles, ligaments and tendons. Most patients with FOP are misdiagnosed early in life before the appearance of h...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1426-1
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:Although not validated fully, recommendations are present for diagnosis, screening and treatment modalities of patients with familial Mediterranean fever (FMF). OBJECTIVE:To review the current practices of clinicians regarding FMF and reveal their adherence to consensus guidelines. METHODS:Fifteen key poin...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-020-04776-1
更新日期:2021-01-16 00:00:00
abstract::Although several effects of electromagnetic fields (EMFs) on articular cartilage have been reported in recent studies, the use of EMFs to treat osteoarthritis remains a matter of debate. In an in vitro study, human chondrocytes harvested from osteoarthritic knee joints were released from their surrounding matrix and t...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0565-0
更新日期:2008-08-01 00:00:00
abstract::This study was designed to investigate the association of oral ulceration and oral health factors, together with psycho-social well-being in Behçet's disease (BD), and to clarify the importance of psycho-social support of patients in the overall management of BD. The study comprised of a cohort of 146 BD patients (mea...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-018-4117-y
更新日期:2018-10-01 00:00:00
abstract::Agalactosyl IgG [Gal(0)] was first discovered in patients with rheumatoid arthritis (RA). However, the proportion of this glycoform is also raised in tuberculosis and leprosy. This has helped reinforce the suggestion that RA may be triggered by a mycobacterium-like slow bacterial infection. On the other hand, arthriti...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00262090
更新日期:1995-01-01 00:00:00
abstract::Cardiovascular disease (CVD) morbidity and mortality is highly prevalent in patients with rheumatoid arthritis (RA) with debilitating effects for the individual as well as significant healthcare impact. Current evidence demonstrates that engaging in aerobic and resistance exercise (i.e. structured physical activity) c...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-019-04483-6
更新日期:2020-03-01 00:00:00
abstract::Nitric oxide (NO) is a free radical that plays important roles in many physiological and pathological processes. Evidence suggests that NO participates in the pathogenesis of inflammatory reactions in many autoimmune and inflammatory diseases such as rheumatoid arthritis (RA). The purpose of this study was to evaluate...
journal_title:Rheumatology international
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s002960100105
更新日期:2001-05-01 00:00:00
abstract::Autophagosomes are formed during autophagy, which is activated by hypoxia and starvation. Autophagy is important for mast cell degranulation. We hypothesized that autophagy is a key feature in the pathogenesis of systemic sclerosis (SSc). We examined SSc clinical features and mast cell density across the presence and ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-013-2827-8
更新日期:2014-03-01 00:00:00
abstract::The objectives of this study are to describe appropriateness and drug treatment of comorbidities in fibromyalgia (FM). Cross-sectional study of a group of patients. Number of drugs, indication, duration and appropriateness of prescriptions were evaluated. Patients were classified as: group 1, (FM/FM) previous FM diagn...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-016-3568-2
更新日期:2016-12-01 00:00:00
abstract::To define the relationship between serum anti-cyclic citrullinated peptide antibodies (anti-CCP) and disease activity, and to construct a new disease activity index by using anti-CCP in rheumatoid arthritis (RA). One hundred and five RA patients were included. Disease activity based on DAS28-ESR and serum anti-CCP was...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-011-2282-3
更新日期:2012-12-01 00:00:00
abstract::The aim of the study is to investigate the levels of serum interleukin-35 (IL-35) before and after treatment and its relationship with clinical parameters as well as the frequency of different subsets of CD4+ T cells in patients with systemic sclerosis (SSc) to explore the role of IL-35 in the pathogenesis of SSc. The...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-018-4071-8
更新日期:2018-08-01 00:00:00
abstract::Spondyloarthropathy refers to any joint disease of the vertebral column, but the term is mainly used for a specific group of disorders called seronegative spondyloarthropathies (SpAs). The axial skeletal involvement, peripheral and extra-articular manifestations and an association with the major histocompatibility com...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-019-04346-0
更新日期:2019-09-01 00:00:00
abstract::Autoimmune diseases (AID) are caused by the loss of immunological tolerance against self-antigens. The deoxyribonuclease I (DNASE1) gene seems to participate in the genetic susceptibility of some AID. In fact, two mutations were reported among systemic lupus erythematosus (SLE) patients from Japan and Spain (the 172 A...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-0917-4
更新日期:2009-11-01 00:00:00
abstract::Systematic reviews and meta-analyses of randomized trials have long been important synthesis tools for guiding evidence-based medicine. More recently, network meta-analyses, an extension of traditional meta-analyses enabling the comparison of multiple interventions, use new statistical methods to incorporate clinical ...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-014-2994-2
更新日期:2014-11-01 00:00:00
abstract::Antibodies to citrullinated proteins have been described in patients with rheumatoid arthritis (RA) and these appear to be the most specific markers of the disease. Our objective was to determine the frequency of antibodies to cyclic citrullinated peptides (CCPs) in patients with RA and the association of anti-CCP ant...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0570-3
更新日期:2008-08-01 00:00:00
abstract::We report a 53-year-old Turkish female presented with progressive weakness and mild dyspnea. Laboratory results demonstrated severe hypokalemia with hyperchloremic metabolic acidosis. The urinary anion gap was positive in the presence of acidemia, thus she was diagnosed with hypokalemic paralysis from a severe distal ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-011-2322-z
更新日期:2013-07-01 00:00:00
abstract::To establish whether a cadaver model can serve as an effective surrogate for the detection of tendon damage characteristic of rheumatoid arthritis (RA). In addition, we evaluated intraobserver and interobserver agreement in the grading of RA-like tendon tears shown by US, as well as the concordance between the US find...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-016-3460-0
更新日期:2016-06-01 00:00:00