Changes in synovial fluid biochemical markers following arthroscopic surgery in patients with knee osteoarthritis.

Abstract:

:Although arthroscopic surgery (AS) for knee osteoarthritis has been widely employed, scientific evidence is lacking. The purpose of this study was to investigate temporal changes in synovial fluid levels of biochemical markers associated with cartilage metabolism following AS. Twenty-five knees of 24 patients with medial knee osteoarthritis (mean age 70.5 years) were included in this study. Synovial fluids were sampled immediately before surgery and 2, 4, 8, and 12 weeks after AS. Levels of the biochemical markers chondroitin 6-sulfate (C6S), chondroitin 4-sulfate (C4S), and keratan sulfate (KS) were measured and correlations among the biochemical markers were analyzed before and after surgery. C6S, C4S, and total CS levels were the same before and after surgery; however, the KS level decreased significantly at 2 weeks after AS. A strong, positive correlation was detected between C6S and KS levels at 12 weeks, differing from the weaker correlation seen before surgery. Seven of the patients required total or unicompartmental knee arthroplasties in the 2 years following AS. In this study, the significant reduction in KS levels and the strong correlation between C6S and KS levels were shown, which indicates suppressed cartilage turnover after AS. Exploring predictive factors indicating favorable or unfavorable outcomes from AS will be important future studies.

journal_name

Rheumatol Int

authors

Nakajima A,Nakagawa K,Aoki Y,Sonobe M,Shibata Y,Yamazaki M,Murakami M

doi

10.1007/s00296-012-2374-8

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

209-14

issue

1

eissn

0172-8172

issn

1437-160X

journal_volume

33

pub_type

杂志文章
  • Systemic lupus erythematosus associated with Wells' syndrome.

    abstract::Wells' syndrome is a multifaceted dermatosis with a wide morphological spectrum, ranging from characteristic cellulitis-like erythema and papula to an unusual presentation of vesicles and pustules. The most important elements for diagnosis are erythemal plaques and histological picture of eosinophilic infiltration of ...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-011-1809-y

    authors: Yin G,Xie Q

    更新日期:2012-04-01 00:00:00

  • Comparison of phenotype expression by mononuclear phagocytes within subcutaneous gouty tophi and rheumatoid nodules.

    abstract::The mononuclear phagocyte infiltrate which occupies the gout tophus has been compared with that of the subcutaneous rheumatoid nodule. In the gout tophus, macrophage migration appears to be at a relatively low level and effectively terminates once these cells have been recruited into the corona. In the nodule the evid...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/BF00541376

    authors: Palmer DG,Hogg N,Denholm I,Allen CA,Highton J,Hessian PA

    更新日期:1987-01-01 00:00:00

  • Enzyme-linked immunosorbent assays for antibodies to poly(A), poly dAT and histones: possibly useful tools for the evaluation of prognosis and disease activity in systemic lupus erythematosus.

    abstract::In a prospective study 222 sera from 56 patients with systemic lupus erythematosus (SLE) were tested for antibodies to poly(A), poly dAT and histones using enzyme-linked immunosorbent assay (ELISA). Patients with active disease had significantly more often antibodies to poly(A), poly dAT and histones than patients wit...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/BF00541200

    authors: Helve T,Gripenberg M,Kurki P,Teppo AM,Wegelius O

    更新日期:1984-01-01 00:00:00

  • Reversible depletion of synovial lining cells after intra-articular treatment with liposome-encapsulated dichloromethylene diphosphonate.

    abstract::We studied the depletion and repopulation of synovial lining cells in mice. A single intra-articular injection of liposomes encapsulating the drug dichloromethylene diphosphonate (CL2MDP) in the mouse knee joint caused selective elimination of synovial lining cells. Depletion of cells occurred within a few days as evi...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/BF00290330

    authors: van Lent PL,van den Bersselaar L,van den Hoek AE,van de Ende M,Dijkstra CD,van Rooijen N,van de Putte LB,van den Berg WB

    更新日期:1993-01-01 00:00:00

  • The PADI4 gene does not contribute to genetic susceptibility to rheumatoid arthritis in Chinese Han population.

    abstract::The Peptidyl arginine deiminase, type IV (PADI4) gene has been suggested to have an association with rheumatoid arthritis (RA) in several populations. But its role in Chinese RA is not clarified. We investigated five single-nucleotide polymorphisms (SNPs) of PADI4 as PADI4-89 (rs11203366), PADI4-90 (rs11203367), PADI4...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-010-1519-x

    authors: Chen R,Wei Y,Cai Q,Duan S,Ren D,Shen J,He D,Fang M,Lv K,Cheng N,Sun S

    更新日期:2011-12-01 00:00:00

  • Familial Takayasu's arteritis in female siblings.

    abstract::Takayasu's arteritis (TA) is a rare chronic vasculitis of the aorta and its main branches. Infectious agents or autoimmunity are thought to influence the pathophysiology. Ethnic preponderance in East Asia and usually affects young Asian women suggesting a possible role of genetic factor in the etiology. We present a r...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-009-1234-7

    authors: Heo JH,Kim M

    更新日期:2011-06-01 00:00:00

  • The effects of an oral preparation containing hyaluronic acid (Oralvisc®) on obese knee osteoarthritis patients determined by pain, function, bradykinin, leptin, inflammatory cytokines, and heavy water analyses.

    abstract::The purpose of this study was to determine the effects of an oral preparation containing hyaluronic acid on osteoarthritic knee joint pain and function as well as changes in inflammatory cytokines, bradykinin, and leptin. We also used heavy water to determine the turnover rates of glycosaminoglycans in synovial fluid....

    journal_title:Rheumatology international

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00296-014-3047-6

    authors: Nelson FR,Zvirbulis RA,Zonca B,Li KW,Turner SM,Pasierb M,Wilton P,Martinez-Puig D,Wu W

    更新日期:2015-01-01 00:00:00

  • Arthritic presentation of childhood malignancy: beware of normal blood counts.

    abstract::Some children with malignancy (e.g. acute lymphoblastic leukemia) who initially present with musculoskeletal complaints may be misdiagnosed as having a rheumatological disorder. In the literature, importance has been given to subtle changes in blood counts, which may point toward an underlying malignancy. We report 3 ...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-010-1584-1

    authors: Suri D,Ahluwalia J,Sachdeva MU,Das R,Varma N,Singh S

    更新日期:2011-06-01 00:00:00

  • Clinical spectrum and therapeutics in Canadian patients with anti-melanoma differentiation-associated gene 5 (MDA5)-positive dermatomyositis: a case-based review.

    abstract::The objective of the study was to determine the clinical features and treatment course in Canadian patients with dermatomyositis (DM) associated with the anti-melanoma differentiation-associated gene 5 antibody (MDA5). A retrospective chart review of consecutive patients with anti-MDA5 antibody DM from two Canadian te...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s00296-019-04398-2

    authors: Huang K,Vinik O,Shojania K,Yeung J,Shupak R,Nimmo M,Avina-Zubieta JA

    更新日期:2019-11-01 00:00:00

  • Non-Hodgkin's lymphoma following treatment with etanercept in ankylosing spondylitis.

    abstract::Anti-TNF drugs may increase lymphoma risk in autoimmune rheumatic diseases, such as rheumatoid arthritis, but there have been no reports stating increased risk of lymphoma in ankylosing spondylitis (AS). Before 2 years, we had presented a case with AS developing Hodgkin's lymphoma following 6 months of etanercept trea...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-009-1265-0

    authors: Aksu K,Cagirgan S,Ozsan N,Keser G,Sahin F

    更新日期:2011-12-01 00:00:00

  • A case of pure red cell aplasia and systemic lupus erythematosus caused by human parvovirus B19 infection.

    abstract::Human parvovirus B19 (B19) rarely induces pure red cell aplasia (PRCA) in healthy hosts. Meanwhile B19 infection is often clinically similar to systemic lupus erythematosus (SLE), and several cases have been reported wherein B19 actually stimulated SLE exacerbation in an immunocompetent subject. An 82-year-old healthy...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-006-0227-z

    authors: Ideguchi H,Ohno S,Ishigatsubo Y

    更新日期:2007-02-01 00:00:00

  • Gout: a critical analysis of scientific development.

    abstract::In recent years, scientific efforts on the topic "gout" have focused on pathogenetic aspects. This has opened new strategies of anti-inflammatory therapy and has improved urate-lowering therapy. So far, a scientometric analysis of the topic "gout" has not been generated despite an increased need for it in times of mod...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-013-2805-1

    authors: Gerber A,Groneberg DA,Klingelhöfer D,Bundschuh M

    更新日期:2013-11-01 00:00:00

  • Relapsing polychondritis with aortic arch aneurysm and aortic arch syndrome.

    abstract::A case of relapsing polychondritis with aortic arch aneurysm and aortic arch syndrome is described. The pattern of vascular involvement supports the inclusion of relapsing polychondritis within the spectrum of systemic vasculitides. ...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/BF00541214

    authors: Giordano M,Valentini G,Sodano A

    更新日期:1984-01-01 00:00:00

  • Felty syndrome: autoimmune neutropenia or immune-complex-mediated disease?

    abstract::Immunofluorescence on polymorphonuclear cells (PMN) of patients with Felty syndrome (FS) revealed increased amounts of IgG, IgA, and IgM bound to the PMN surface compared with PMN of patients with rheumatoid arthritis alone. A positive correlation was found between the score for surface-bound immunoglobulins on FS-PMN...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/BF00541352

    authors: Breedveld FC,Lafeber GJ,Doekes G,Claas FH,Cats A

    更新日期:1985-01-01 00:00:00

  • Cross-cultural adaptation and validation of the Thai version of the Rheumatoid Arthritis Disease Activity Index (RADAI).

    abstract::The objective of this study was to translate and evaluate the psychometric properties of the Thai version of the Rheumatoid Arthritis Disease Activity Index (RADAI) in patients with rheumatoid arthritis (RA). We translated and modified the original RADAI into the Thai version. A total of 116 Thai patients with RA were...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-013-2749-5

    authors: Katchamart W,Ussavasodhi P,Chiowchanwesawakit P,Chanapai W

    更新日期:2013-10-01 00:00:00

  • Establishing hospital admission criteria of pediatric Henoch-Schonlein purpura.

    abstract::The current study aimed to define evidence-based admission criteria of pediatric Henoch-Schonlein purpura (HSP). In addition, we aimed to better characterize epidemiological and clinical features of pediatric HSP in Israel. We performed a retrospective cohort study of all children with HSP admitted during a 15 years p...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-014-2971-9

    authors: Masarweh K,Horovitz Y,Avital A,Spiegel R

    更新日期:2014-11-01 00:00:00

  • Adherence to best practice consensus guidelines for familial Mediterranean fever: a modified Delphi study among paediatric rheumatologists in Turkey.

    abstract:BACKGROUND:Although not validated fully, recommendations are present for diagnosis, screening and treatment modalities of patients with familial Mediterranean fever (FMF). OBJECTIVE:To review the current practices of clinicians regarding FMF and reveal their adherence to consensus guidelines. METHODS:Fifteen key poin...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-020-04776-1

    authors: Kavrul Kayaalp G,Sozeri B,Sönmez HE,Demir F,Cakan M,Oztürk K,Karadag SG,Otar Yener G,Ozdel S,Baglan E,Celikel E,Sahin N,Gezgin Yildirim D,Eker Omeroglu R,Aktay Ayaz N,PeRA-Research Group.

    更新日期:2021-01-16 00:00:00

  • Smoking, disease activity, permanent damage and dsDNA autoantibody production in patients with systemic lupus erythematosus.

    abstract::The aim was to study the association of smoking with the activity and severity of systemic lupus erythematosus (SLE) and the production of antibodies to dsDNA. The study included 223 SLE patients attending the outpatient clinics at Helsinki University Central Hospital. The history of smoking was obtained by personal i...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-013-2889-7

    authors: Ekblom-Kullberg S,Kautiainen H,Alha P,Leirisalo-Repo M,Miettinen A,Julkunen H

    更新日期:2014-03-01 00:00:00

  • Experimental immune mediated arthritis in rhesus monkeys. A model for human rheumatoid arthritis?

    abstract::The induction of experimental arthritis in rhesus monkeys was studied by intradermal immunization of bovine type II collagen and antigens derived from Mycobacterium tuberculosis, Streptococcus pyogenes, and Eubacterium aerofaciens. The tested bacterial antigens proved to be not arthrogenic. Bovine type II collagen ind...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/BF02274777

    authors: Bakker NP,van Erck MG,Zurcher C,Faaber P,Lemmens A,Hazenberg M,Bontrop RE,Jonker M

    更新日期:1990-01-01 00:00:00

  • Cytokine enhancement of monocyte/synovial cell attachment to the surface of cartilage: a possible trigger of pannus formation in arthritis.

    abstract::When rheumatoid articular cartilage samples were incubated with normal peripheral blood monocytes and cultured synovial cells in the presence of recombinant human interleukin-1 (IL-1) in vitro, large numbers of monocytes were seen to be attached to the articular surface. Significant numbers of monocytes invaded the ca...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/BF00290248

    authors: Ishikawa H,Ohno O,Saura R,Matsubara T,Kuroda T,Hirohata K

    更新日期:1991-01-01 00:00:00

  • The inflammatory circuitry of miR-149 as a pathological mechanism in osteoarthritis.

    abstract::Osteoarthritis (OA) is a multifactorial degenerative pathology, whose progression is exacerbated by pro-inflammatory cytokines signaling. Among the changes triggered in chondrocytes during inflammation, modified expression of tiny epigenetic regulators as microRNAs was shown having deleterious implications for articul...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-013-2754-8

    authors: Santini P,Politi L,Vedova PD,Scandurra R,Scotto d'Abusco A

    更新日期:2014-05-01 00:00:00

  • Monitoring of therapeutic efficacy in a patient with RS₃PE syndrome by serologic variables and radiographic methods.

    abstract::We describe a typical case of a patient with remitting seronegative symmetrical synovitis and pitting edema (RS(3)PE) syndrome. He underwent a successful clinical course monitored by serologic variables and radiographic methods. Serum levels of interleukin-6 (IL-6), vascular endothelial growth factor (VEGF), matrix me...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-009-1142-x

    authors: Kawashiri SY,Nakano M,Kawakami A,Eguchi K

    更新日期:2010-11-01 00:00:00

  • Level of agreement between three-dimensional volumetric ultrasound and real-time conventional ultrasound in the assessment of synovitis, tenosynovitis and erosions in rheumatoid arthritis patients.

    abstract::The aim of the study was to assess agreement between three-dimensional volumetric ultrasound (3D US) performed by inexperienced staff and real-time conventional ultrasound (2D US) performed by experienced rheumatologists in detecting and scoring rheumatoid arthritis (RA) lesions. Thirty-one RA patients underwent exami...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-016-3606-0

    authors: Acebes C,McKay N,Ciechomska A,Alcorn N,Harvie JP,Robson B,Groenendijk N,McDonald M,Wilson A,Garrido J

    更新日期:2017-02-01 00:00:00

  • Is psychological distress intrinsic to fibromyalgia syndrome? Cross-sectional analysis in two clinical presentations.

    abstract::Clinical presentation of fibromyalgia syndrome (FMS) is heterogeneous and often involves psychological comorbidities. Clinical subgrouping of FMS patients has been proposed as a strategy to improve patients' long-term outcomes by helping identify specific treatment needs. Using the 90 Symptom Checklist Revised (SCL-90...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-011-2199-x

    authors: Salgueiro M,Aira Z,Buesa I,Bilbao J,Azkue JJ

    更新日期:2012-11-01 00:00:00

  • Chitotriosidase as a marker of disease activity in sarcoidosis.

    abstract::Sarcoidosis is a chronic granulomatous inflammation. The clinical spectrum in childhood is heterogeneous. Angiotensin converting enzyme activity is used as a marker for disease activity. Human chitotriosidase is produced in macrophages. In this study, serum chitotriosidase levels were significantly higher in active sa...

    journal_title:Rheumatology international

    pub_type: 信件

    doi:10.1007/s00296-007-0318-5

    authors: Brunner J,Scholl-Bürgi S,Prelog M,Zimmerhackl LB

    更新日期:2007-10-01 00:00:00

  • OPG inhibits gene expression of RANK and CAII in mouse osteoclast-like cell.

    abstract::This study was designed to determine the effects of the osteoprotegerin (OPG) on the mRNA expression of carbonic anhydrase II (CAII) and the receptor activator of NF-κB (RANK) in mouse osteoclast-like cells. Marrow cells were harvested from femora and tibiae of mouse and cultured in 6-well chamber slides. After 1 day ...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-011-2338-4

    authors: Chen J,He JQ,Zhen SY,Huang LQ

    更新日期:2012-12-01 00:00:00

  • Neprilysin levels in plasma and synovial fluid of juvenile idiopathic arthritis patients.

    abstract:OBJECTIVE:Neprilysin (neutral endopeptidase, 3:4:24:11, CD10) (NEP) is a Zn metallopeptidase linked to controlling inflammation through the degradation of neuropeptides involved in neurogenic inflammation of chronic rheumatic diseases. The aim of our study was to evaluate circulating activity and cellular expression of...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-004-0447-z

    authors: Simonini G,Azzari C,Gelli AM,Giani T,Calabri GB,Leoncini G,Del Rosso A,Generini S,Cimaz R,Cerinic MM,Falcini F

    更新日期:2005-06-01 00:00:00

  • Common variants of a urate-associated gene LRP2 are not associated with gout susceptibility.

    abstract::A recent genome-wide association study revealed that there is an association between serum uric acid (SUA) levels and rs2544390, a common variant in low-density lipoprotein-related protein 2 (LRP2/Megalin) gene. Two other variants of LRP2, rs2229268 and rs3755166, are also found to have associations with dyslipidemia ...

    journal_title:Rheumatology international

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00296-013-2924-8

    authors: Nakayama A,Matsuo H,Shimizu T,Takada Y,Nakamura T,Shimizu S,Chiba T,Sakiyama M,Naito M,Morita E,Ichida K,Shinomiya N

    更新日期:2014-04-01 00:00:00

  • Markers of endothelial damage and repair in Takayasu arteritis: are they associated with disease activity?

    abstract::The current clinical and laboratory parameters of Takayasu arteritis (TA) are insufficient for proper assessment of disease activity. The aims of this study were to investigate the markers of endothelial injury and repair, including circulating endothelial cell (CEC), circulating endothelial progenitor cell (CEPC) and...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-013-2937-3

    authors: Dogan S,Piskin O,Solmaz D,Akar S,Gulcu A,Yuksel F,Cakır V,Sari I,Akkoc N,Onen F

    更新日期:2014-08-01 00:00:00

  • Comparative aspects of murine proteinase 3.

    abstract::The neutrophilic granule protein proteinase 3 (PR3) is the preferred target antigen of anti-neutrophil cytoplasmic antibodies (ANCA) found in the serum of patients with Wegener's granulomatosis, a systemic small-vessel vasculitis. Due to the lack of data concerning the murine homologue of human PR3, we assessed the ne...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-010-1672-2

    authors: Relle M,Thomaidis T,Galle PR,Schwarting A

    更新日期:2011-08-01 00:00:00