Systemic lupus erythematosus associated with Wells' syndrome.


:Wells' syndrome is a multifaceted dermatosis with a wide morphological spectrum, ranging from characteristic cellulitis-like erythema and papula to an unusual presentation of vesicles and pustules. The most important elements for diagnosis are erythemal plaques and histological picture of eosinophilic infiltration of the dermis with 'flame figures' (Plotz et al., in Hautarzt 51:182-186, 2000). Because of its original description as a distinct entity, it has come to be regarded as an abnormal eosinophilic response to a number of causative agents such as herpes simplex virus 2(HSV-2) and toxocara (Ludwig et al., in J Am Acad Dermatol 48:S60-S61, 2003; Bassukas et al., in Cases J 1:356, 2008). Concurrence of WS and malignant diseases as colon cancer, trachea squamous carcinoma, nasopharyngeal carcinoma or angioimmunoblastic lymphadenopathy has been reported (Hirsch et al., in J Dtsch Dermatol Ges 3:530-531, 2005; Renner et al., in Acta Derm Venereol 87:525-528, 2007). Autoimmune diseases, including Systemic lupus erythematosus (SLE) are multi-system disorders of unknown cause and are commonly characterized by protean cutaneous manifestations. To date, few autoimmne disease was found associated with WS except four previous reports of Churg-Strauss syndrome (CSS) and one case of ulcerative colitis (Fujimoto et al., in Clin Exp Dermatol, 2010; Sakaria et al., in J Gastroenterol 42:250-252, 2007). The coexistence of SLE and WS in one patient was not found in literature and our case is the first. Here we described the rare combination and discussed the treatment strategy for this condition.


Rheumatol Int


Yin G,Xie Q




Has Abstract


2012-04-01 00:00:00












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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Holme ER,Veitch J,Johnston A,McKay IC,Whaley K

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  • The inflammatory circuitry of miR-149 as a pathological mechanism in osteoarthritis.

    abstract::Osteoarthritis (OA) is a multifactorial degenerative pathology, whose progression is exacerbated by pro-inflammatory cytokines signaling. Among the changes triggered in chondrocytes during inflammation, modified expression of tiny epigenetic regulators as microRNAs was shown having deleterious implications for articul...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Santini P,Politi L,Vedova PD,Scandurra R,Scotto d'Abusco A

    更新日期:2014-05-01 00:00:00

  • Prevalence and annual incidence of vertebral fractures in patients with ankylosing spondylitis.

    abstract:OBJECTIVES:To evaluate the prevalence and annual incidence of clinically-manifest vertebral fractures among patients with ankylosing spondylitis (AS). METHOD:Coordinated by the Ankylosing Spondylitis International Federation, a self-administered general questionnaire which included some questions on gender, age, age a...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Feldtkeller E,Vosse D,Geusens P,van der Linden S

    更新日期:2006-01-01 00:00:00

  • Antineutrophil cytoplasmic antibodies in patients with systemic lupus erythematosus: prevalence, antigen specificity, and clinical associations.

    abstract::Fifty-five patients with systemic lupus erythematosus (SLE) were examined for antineutrophil cytoplasmic antibodies (ANCA) by indirect immunofluorescence (IIF). Enzyme-linked immunosorbent assay (ELISA) for ANCA against myeloperoxidase (MPO), lactoferrin (LF), proteinase 3 (PR3), elastase (HLE), and bactericidal/perme...

    journal_title:Rheumatology international

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    authors: Manolova I,Dancheva M,Halacheva K

    更新日期:2001-07-01 00:00:00

  • Punctal plugs versus artificial tears for treating primary Sjögren's syndrome with keratoconjunctivitis SICCA: a comparative observation of their effects on visual function.

    abstract::To compare the effects of treatment with punctal plugs versus artificial tears on visual function for primary Sjögren's syndrome with dry eye. Forty-two eyes of 42 patients with primary Sjögren's syndrome were enrolled and were allocated randomly into artificial tears (AT) group and punctal plugs (PP) group. Ocular Su...

    journal_title:Rheumatology international

    pub_type: 杂志文章,随机对照试验


    authors: Qiu W,Liu Z,Ao M,Li X,Wang W

    更新日期:2013-10-01 00:00:00

  • Total oxidative/anti-oxidative status and relation to bone mineral density in osteoporosis.

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Altindag O,Erel O,Soran N,Celik H,Selek S

    更新日期:2008-02-01 00:00:00

  • Biomarkers of hand osteoarthritis.

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    journal_title:Rheumatology international

    pub_type: 杂志文章,评审


    authors: Lennerová T,Pavelka K,Šenolt L

    更新日期:2018-05-01 00:00:00

  • Epidemiological study of adult-onset Still's disease using a Japanese administrative database.

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Sakata N,Shimizu S,Hirano F,Fushimi K

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  • Felty syndrome: autoimmune neutropenia or immune-complex-mediated disease?

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Breedveld FC,Lafeber GJ,Doekes G,Claas FH,Cats A

    更新日期:1985-01-01 00:00:00

  • Patients with the most advanced rheumatoid arthritis remain with Th1 systemic defects after TNF inhibitors treatment despite clinical improvement.

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Kosmaczewska A,Swierkot J,Ciszak L,Szteblich A,Chrobak A,Karabon L,Partyka A,Szechinski J,Wiland P,Frydecka I

    更新日期:2014-02-01 00:00:00

  • Disseminated multiple ostial stenoses in a young woman presenting as unstable angina.

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Lee SH,Chae JK,Lim ST,Ko JK

    更新日期:2009-04-01 00:00:00

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Spacek P,Adam M

    更新日期:2006-08-01 00:00:00

  • Etodolac: efficacy in osteoarthritis and effects on chondrocyte function.

    abstract::Some nonsteroidal anti-inflammatory drugs (NSAIDs) used in the treatment of osteoarthritis (OA) may damage articular cartilage. This damage may be caused by suppression of proteoglycan synthesis or by altered collagen synthesis in the presence of prostaglandin E2 (PGE2) induced by interleukin-1 (IL-1). The clinical an...

    journal_title:Rheumatology international

    pub_type: 临床试验,杂志文章,评审


    authors: Bacon PA

    更新日期:1990-01-01 00:00:00

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    abstract::Elderly often have Heberden nodes (HN) and Bouchard nodes (BN) that may affect finger dexterity. The aim of this cross-sectional study was to assess an effect of HN and BN on finger dexterity of the elderly. The nine-hole peg test was used for dexterity measurement in 200 elderly with HN and/or BN. Mean age was 68.6 +...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Kitisomprayoonkul W,Promsopa K,Chaiwanichsiri D

    更新日期:2010-02-01 00:00:00

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    更新日期:2017-01-01 00:00:00

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Knipp S,Feyen O,Ndagijimana J,Niehues T

    更新日期:2003-05-01 00:00:00

  • Comparing fibromyalgia patients from primary care and rheumatology settings: clinical and psychosocial features.

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    journal_title:Rheumatology international

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    authors: Boyer AL,Mira Pastor MA,Calatayud NP,Lopez-Roig S,Cantero Terol MC

    更新日期:2009-08-01 00:00:00

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Franck H,Gottwalt J

    更新日期:2008-11-01 00:00:00

  • Macrophage activation syndrome in malaria.

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Dass R,Barman H,Duwarah SG,Choudhury V,Jain P,Deka NM,Murari M

    更新日期:2010-06-01 00:00:00

  • Parenchymal neuro-Behçet disease with erectile dysfunction and micturition disturbances: case report and literature review.

    abstract::Parenchymal neuro-Behçet disease (NBD) is a serious clinic condition with a sub-acute or chronic disease course that results in incapability through pyramidal tract involvement. Though well-known consequences can deter a patient's life, both urinary symptoms and sexual dysfunction are underestimated complications of N...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审


    authors: Taylan A,Birlik M

    更新日期:2018-01-01 00:00:00

  • Associations of cigarette smoking with disease phenotype and type I interferon expression in primary Sjögren's syndrome.

    abstract::Several studies have shown a negative association between smoking and primary Sjögren's syndrome (pSS), and smoking may interfere with the immune response. The purpose of this study was to investigate if smoking affects disease activity and disease phenotype in pSS. In this cross-sectional study, consecutive pSS patie...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Olsson P,Bodewes ILA,Nilsson AM,Turesson C,Jacobsson LTH,Theander E,Versnel MA,Mandl T

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Al Attia HM,Jaysundaram K,Saraj F

    更新日期:2010-01-01 00:00:00

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Inanc N,Direskeneli H

    更新日期:2006-11-01 00:00:00

  • Scleroderma pattern of nailfold capillary changes as predictive value for the development of a connective tissue disease: a follow-up study of 3,029 patients with primary Raynaud's phenomenon.

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Pavlov-Dolijanovic S,Damjanov NS,Stojanovic RM,Vujasinovic Stupar NZ,Stanisavljevic DM

    更新日期:2012-10-01 00:00:00

  • Performance of subjects with knee osteoarthritis during walking: differential parameters.

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Esrafilian A,Karimi MT,Amiri P,Fatoye F

    更新日期:2013-07-01 00:00:00

  • Reduction in jaw opening: a neglected symptom of giant cell arteritis.

    abstract::Reduction in jaw opening is a neglected symptom of giant cell arteritis (GCA) in clinical practice and in the scientific literature. We describe the case of a 71-year-old woman with GCA who was misdiagnosed as occipital neuritis and craniomandibular dysfunction because of headaches in the occipital region and reductio...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Kraemer M,Metz A,Herold M,Venker C,Berlit P

    更新日期:2011-11-01 00:00:00

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Osgood E,Trudeau JJ,Eaton TA,Jensen MP,Gammaitoni A,Simon LS,Katz N

    更新日期:2015-06-01 00:00:00

  • Investigation of the human FCRL1, 2, and 4 gene expressions in patients with rheumatoid arthritis.

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Khanzadeh A,Habibagahi Z,Hosseini A,Amirghofran Z

    更新日期:2016-08-01 00:00:00

  • Prevalence of other connective tissue diseases in idiopathic inflammatory myopathies.

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Maundrell A,Proudman S,Limaye V

    更新日期:2019-10-01 00:00:00

  • Primary Sjögren's syndrome in Moroccan patients: characteristics, fatigue and quality of life.

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Ibn Yacoub Y,Rostom S,Laatiris A,Hajjaj-Hassouni N

    更新日期:2012-09-01 00:00:00