Abstract：
:Some children with malignancy (e.g. acute lymphoblastic leukemia) who initially present with musculoskeletal complaints may be misdiagnosed as having a rheumatological disorder. In the literature, importance has been given to subtle changes in blood counts, which may point toward an underlying malignancy. We report 3 children with malignancy, who had an arthritic presentation but had normal blood counts at presentation. Atypical clinical pattern, significant nocturnal pain, pain out of proportion to joint involvement and prominent systemic features in these children prompted us to do a bone marrow examination that revealed a malignancy. Pediatricians must be aware of the arthritic presentation of childhood malignancy. If the clinical features point toward a malignancy, bone marrow examination should always be performed even if the blood counts are normal.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Suri D,Ahluwalia J,Sachdeva MU,Das R,Varma N,Singh Sdoi
10.1007/s00296-010-1584-1subject
Has Abstractpub_date
2011-06-01 00:00:00pages
827-9issue
6eissn
0172-8172issn
1437-160Xjournal_volume
31pub_type
杂志文章abstract：:Systemic lupus erythematosus (SLE) is a chronic inflammatory disease that can lead to damage to several vital organs. Antiphospholipid syndrome (APS), manifesting as vascular thromboembolic events and morbidities of pregnancy in the presence of antiphospholipid antibodies (aPL), has been described in patients with SLE...
journal_title：Rheumatology international
pub_type： 信件
doi：10.1007/s00296-011-1826-x
更新日期：2012-03-01 00:00:00
abstract：:We studied the depletion and repopulation of synovial lining cells in mice. A single intra-articular injection of liposomes encapsulating the drug dichloromethylene diphosphonate (CL2MDP) in the mouse knee joint caused selective elimination of synovial lining cells. Depletion of cells occurred within a few days as evi...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00290330
更新日期：1993-01-01 00:00:00
abstract：:The goal of this study was to investigate the persistence with biological drugs in patients treated in rheumatology practices in Germany. This study included patients diagnosed with rheumatoid arthritis (RA), psoriatic arthritis (PA), or ankylosing spondylitis (AS) who received a first prescription of biological drugs...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-018-4194-y
更新日期：2019-03-01 00:00:00
abstract：:The Peptidyl arginine deiminase, type IV (PADI4) gene has been suggested to have an association with rheumatoid arthritis (RA) in several populations. But its role in Chinese RA is not clarified. We investigated five single-nucleotide polymorphisms (SNPs) of PADI4 as PADI4-89 (rs11203366), PADI4-90 (rs11203367), PADI4...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1519-x
更新日期：2011-12-01 00:00:00
abstract：:Antibodies to DNA are quite specific for systemic lupus erythematosus (SLE) and occur in the majority of SLE patients. Therefore, their detection is an important diagnostic aid to the clinician. Detection of anti-dsDNA may precede the diagnosis of SLE by more than a year. Fluctuations in the level of anti-dsDNA in an ...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/BF00304496
更新日期：1991-01-01 00:00:00
abstract：:There are no standardized bedside assessments for subtyping patients with osteoarthritis (OA) based on pain mechanisms. Thus, we developed a bedside sensory testing kit (BSTK) to classify OA patients based on sensory profiles potentially indicative of pain mechanism. After usability and informal reliability testing (n...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-014-3191-z
更新日期：2015-06-01 00:00:00
abstract：:Chlamydia trachomatis (Ct)-induced arthritis (CtIA) is characterized by persistent Ct infection, which stimulates secretion of cytokines in vitro. We therefore investigated whether CtIA patients have a unique cytokine profile in synovial fluid or serum in vivo. Because underlying Ct infection is overlooked in a high p...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-003-0393-1
更新日期：2005-01-01 00:00:00
abstract：:To examine messages perceived by members of an osteoporosis (OP) patient group from various healthcare providers regarding bone health. We conducted a phenomenological (qualitative) study in members of an OP patient group who resided in Canada, had sustained a fragility fracture at 50+ years old, and were not taking a...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-014-3079-y
更新日期：2015-01-01 00:00:00
abstract：:Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening dermatological conditions that are characterized by mucosal erosions, epidermal detachments and erosions. The most common causes of SJS and TEN are drugs; other causes such as systemic lupus erythematosus (SLE), vaccinations and i...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-017-3677-6
更新日期：2017-07-01 00:00:00
abstract：:Several chronic inflammatory disorders, such as rheumatoid arthritis and systemic lupus erythematosus, are associated with an increased risk of coronary artery disease (CAD) as a result of accelerated atherosclerosis. However, the data on CAD risk of polymyalgia rheumatica (PMR), one of the most common chronic inflamm...
journal_title：Rheumatology international
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00296-016-3557-5
更新日期：2017-01-01 00:00:00
abstract：:Objective of the study is to investigate how compliance during the first year of methotrexate (MTX) treatment in rheumatoid arthritis (RA) is influenced by the patients' perception of the necessity for and concern about MTX, the patients' functional disability, and the dose of MTX. A total of 126 RA patients completed...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-1160-8
更新日期：2010-09-01 00:00:00
abstract：:Fibromyalgia (FM) is the most common chronic pain syndrome encountered in medical practice, affecting females more than males, and the estimated prevalence of FM in Egypt is 1.3 %. The aim was to translate and adapt the Fibromyalgia Impact Questionnaire (FIQ) into Arabic and assess reliability and validity. The Arabic...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-013-2779-z
更新日期：2013-10-01 00:00:00
abstract：:A 41-year-old woman with SAPHO syndrome presented with numbness of her left arm followed by a generalized seizure. Computed tomography and magnetic resonance imaging of the brain revealed a small ring enhancing lesion in the right parietal lobe with adjacent meningeal thickening and enhancement. Surgical removal and h...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1464-8
更新日期：2012-06-01 00:00:00
abstract：OBJECTIVES:To evaluate the prevalence and annual incidence of clinically-manifest vertebral fractures among patients with ankylosing spondylitis (AS). METHOD:Coordinated by the Ankylosing Spondylitis International Federation, a self-administered general questionnaire which included some questions on gender, age, age a...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-004-0556-8
更新日期：2006-01-01 00:00:00
abstract：:Rheumatoid arthritis (RA) is a chronic, progressive, debilitating disease that demands continuous therapy with multiple medications. Noncompliance with disease-modifying drugs may cause disease flares, preventable functional impairment, unnecessary treatment changes, and loss of health care resources. The aim of the c...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-2162-x
更新日期：2012-10-01 00:00:00
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journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-018-4004-6
更新日期：2018-06-01 00:00:00
abstract：:Several molecular epidemiological studies have been conducted in recent years to evaluate a possible association between the interferon regulatory factor 5 (IRF5) rs2004640 polymorphism and rheumatoid arthritis risk in diverse populations. However, the results remain conflicting rather than conclusive. Our aim was to ...
journal_title：Rheumatology international
pub_type： 杂志文章,meta分析
doi：10.1007/s00296-013-2806-0
更新日期：2013-11-01 00:00:00
abstract：:Citrulline antibody, nowadays, is a new item which has been the center of attention due to its much more specificity to diagnose RA. The aim of the present study was to evaluate the efficacy and accuracy of anti-citrulline antibody test in RA diagnosis among hospitalized patients in Iran. Through a case-control study,...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-012-2469-2
更新日期：2013-04-01 00:00:00
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journal_title：Rheumatology international
pub_type： 临床试验,杂志文章
doi：10.1007/s00296-011-2078-5
更新日期：2012-10-01 00:00:00
abstract：:A period of 4 weeks (w) has been recommended for rheumatoid arthritis (RA) patients as the interval between intravenous (IV) tocilizumab (TCZ, 8 mg/kg). In a previous paper, we showed the possibility that the interval between successive IV TCZ can be extended from 4 to 6 weeks in more than 60% of patients with low dis...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-018-4149-3
更新日期：2018-12-01 00:00:00
abstract：:We aimed to investigate the diagnostic significance of high frequency ultrasonography (USG), comparing the findings in USG, bone scintigraphy and clinical stuation. Fifty-one patients who had early symptoms of inflammatory arthritis, but not fulfilling the ACR diagnostic criteria for rheumatoid arthritis (RA) were inc...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-008-0765-7
更新日期：2009-05-01 00:00:00
abstract：:A previously healthy 40-year-old woman presented as unstable angina. She had a family history of stroke as the only cardiovascular risk factor. Her blood pressure on admission was 150/90 mmHg. Laboratory study showed absolutely all negative markers of inflammation, autoimmune disorders, or atherosclerosis. Coronary an...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-008-0739-9
更新日期：2009-04-01 00:00:00
abstract：:Systemic sclerosis is a connective tissue disease, which may lead to elevated pulmonary arterial pressure due to pulmonary arterial hypertension and/or left ventricular diastolic dysfunction. Uric acid (UA) has been shown to be elevated in patients with pulmonary hypertension (PH) and heart failure. We aimed to invest...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1557-4
更新日期：2011-02-01 00:00:00
abstract：:Treatment of acute gout consists of non-steroidal anti-inflammatory drugs (NSAIDs), colchicine and steroids. However, the typical patient with gout has multiple comorbidities such as cardiovascular disease, hypertension, renal dysfunction or diabetes/metabolic syndrome that represent contraindications to these therape...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-020-04659-5
更新日期：2020-12-01 00:00:00
abstract：:The objectives of the study were to evaluate the prevalence of antinuclear antibodies (ANA) in patients with fibromyalgia (FM) and the probability of the development of clinically overt connective tissue diseases. Four hundred and fifty FM patients were compared to 129 healthy matched blood donors. ANA testing was per...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-007-0413-7
更新日期：2007-09-01 00:00:00
abstract：:We hypothesise that T-cell apoptosis and the percentage of T cells expressing molecules involved in apoptosis modulation (CD95, CD28) are altered at the inflammation site and in peripheral blood (PB) of children with juvenile idiopathic arthritis (JIA). Paired JIA samples of synovial fluid (SF) and PB ( n=7) and PB sa...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-002-0263-2
更新日期：2003-05-01 00:00:00
abstract：:The objective of the study was to study the clinical utility of the Ankylosing Spondylitis Disease Activity Score (ASDAS) for the assessment of disease activity in ankylosing spondylitis (AS) patients, compared to the Bath Ankylosing Spondylitis Activity Index (BASDAI). This was a prospective longitudinal observationa...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-017-3814-2
更新日期：2017-11-01 00:00:00
abstract：:The aim of this study is to observe the effect of different treatment time of millimeter wave (MMW) on chondrocyte apoptosis, caspase-3, caspase-8, and matrix metalloproteinase-13 (MMP-13) in rabbit knee osteoarthritis induced by anterior cruciate ligament transection (ACLT). Thirty-two New Zealand White rabbits were ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-2080-y
更新日期：2012-09-01 00:00:00
abstract：OBJECTIVE:The aim was to evaluate the efficacy and safety of multiple infusions with achimeric, anti-tumor necrosis factor (TNF)alpha monoclonal antibody (infliximab) in patients with psoriatic arthritis (PsA) and psoriasis vulgaris. METHODS:Over 22 weeks, nine patients with both active psoriasis and PsA received five...
journal_title：Rheumatology international
pub_type： 临床试验,杂志文章
doi：10.1007/s00296-002-0246-3
更新日期：2002-11-01 00:00:00
abstract：:The aim of this study was to investigate the frequency of patients with rheumatoid arthritis (RA) who have inflammatory back pain (IBP) and meet the existing classification criteria for ankylosing spondylitis (AS) and spondyloarthritis (SpA). We included 167 patients fulfilling the ACR 1987 revised criteria for RA. Af...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-012-2553-7
更新日期：2013-05-01 00:00:00
