Abstract：
:Sixty-six hospitalized patients with systemic lupus erythematosus (SLE) were enrolled into this study. The test for anti-mitochondrial antibodies (AMAs) was performed and biochemical parameters were determined. AMAs were detected in 15 of the 66 patients with SLE. Meanwhile, we compared enzymatic levels in AMA-positive and -negative patients and found that serum aminotransferase levels were significantly higher in AMA-positive patients than in AMA-negative individuals. Furthermore, we found a positive correlation between serum AMA titration and serum aminotransferase levels. This study suggests that AMAs might contribute to the elevation of aminotransferases. Although much remains to be learned about the pathogenesis of autoimmune liver disease associated with AMAs, this report might provide greater insight into the metabolic mechanisms of AMAs in AMA-positive patients.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Li CH,Xu PS,Wang CY,Zhang Y,Zou GLdoi
10.1007/s00296-005-0034-ysubject
Has Abstractpub_date
2006-06-01 00:00:00pages
697-703issue
8eissn
0172-8172issn
1437-160Xjournal_volume
26pub_type
杂志文章abstract：:To study the mechanisms of chondrocyte damage, chondrocyte cytotoxicity as shown by chromium-51 release induced by polymorphonuclear leukocytes (PMNLs) was examined. PMNLs significantly enhanced chondrocyte cytotoxicity in the presence of phorbol dibutyrate. This chondrocyte damage was abolished by the addition of cat...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00274933
更新日期：1992-01-01 00:00:00
abstract：:Rheumatoid arthritis (RA) is a multifactorial disease. A combination of genetic and environmental risk factors contributes to its etiology. Several genes have been reported to be associated with susceptibility to the development of RA. The MHC2TA and FCRL3 genes have been associated previously with RA in Swedish and J...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-015-3358-2
更新日期：2016-02-01 00:00:00
abstract：:The objective of this study is to investigate the relationship between clinical features of ankylosing spondylitis (AS) and HLA-B27 status or its subtypes. Clinical data and blood samples were collected with patients' informed consent. Luminex liquid array combining polymerase chain reaction-sequence specific oligonuc...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-008-0743-0
更新日期：2009-02-01 00:00:00
abstract：:The association of familial Mediterranean fever (FMF) and polyarteritis nodosa (PAN) has been well established. These patients have been reported to have an overall better prognosis than other PAN patients. Herein we report a patient with FMF and PAN who died of sepsis following a severe course of recurrent bleeding e...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-003-0424-y
更新日期：2005-01-01 00:00:00
abstract：:31P Magnetic Resonance-Spectroscopy was performed at the site of tender points in the trapezius muscle of patients with primary fibromyalgia syndrome. Earlier, in vitro studies have reported changes in the high energy phosphate-metabolism in biopsies taken from tender points of fibromyalgia patients. The observed alte...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00291145
更新日期：1991-01-01 00:00:00
abstract：:The aim of the present study was to evaluate the effect of long-term leflunomide and methotrexate (MTX) therapy during the course of rheumatoid arthritis (RA) estimated by digital X-ray radiogrammetry (DXR) and computer-aided joint space analysis (CAJSA) as diagnostic tools for the quantification of disease-related pe...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-008-0682-9
更新日期：2009-01-01 00:00:00
abstract：:Regional migratory osteoporosis (RMO) is an idiopathic disorder characterized by severe periarticular pain, transient and migratory arthralgia, and osteoporosis. Osteoporosis in this disease may appear in the form of local regional osteoporosis and bone marrow edema or generalized osteoporosis. It occurs most commonly...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-1256-1
更新日期：2011-10-01 00:00:00
abstract：:Patients with chronic thromboembolic pulmonary hypertension (CTEPH) have poor prognosis, and pulmonary endarterectomy (PEA) is considered the treatment of choice for this condition. We report a case and review the literature of successful PEA for CTEPH due to antiphospholipid syndrome associated with systemic lupus er...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-011-2346-4
更新日期：2013-07-01 00:00:00
abstract：:The thiol status of patients with rheumatoid arthritis is significantly different from that of controls. Plasma thiol levels are lower, albumin thiol reactivity is altered and intracellular thiol levels measured after hemoglobin precipitation are increased. These variations correlate with other indices of disease seve...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00541162
更新日期：1982-01-01 00:00:00
abstract：:The aim of this study was to investigate musculoskeletal ultrasound (MSUS) as a diagnostic modality in DISH and to explore whether it might help in elucidating its pathogenesis and events that precede the calcification/ossification process. Fifty patients with DISH and 34 patients with osteoarthritis of the lower limb...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-014-3190-0
更新日期：2015-03-01 00:00:00
abstract：:Low molecular weight IgM (LMW IgM) is the monomeric subunit of the naturally occurring pentameric IgM. It is not seen in health but has been previously observed in systemic lupus erythematosus (SLE) particularly in those patients with active disease and may reflect an adverse prognostic finding. We have therefore stud...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF02274821
更新日期：1990-01-01 00:00:00
abstract：:Routine assessment of patient index data 3 (RAPID3) is a simple, valid and reliable tool designed to measure disease activity in patients with rheumatoid arthritis (RA). RA causes significant disability and diminishes health-related quality of life (HR-QoL). The aim of this study was to investigate how RAPID3 is relat...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-019-04258-z
更新日期：2019-05-01 00:00:00
abstract：:Tuberculosis (TB) is an important preventable infection in patients with rheumatoid arthritis (RA). To determine the risk of TB in patients with RA by comparing with those with non-specific back pain (NSBP), and to identify the risk factors in the RA group. Medical data were retrieved from a centralized electronic dat...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-020-04583-8
更新日期：2020-06-01 00:00:00
abstract：:Systemic lupus erythematosus (SLE) is a severe complex rheumatic disease, but good estimate of its prevalence and risk factors is lacking in China. The aim of the study was to explore the prevalence of SLE and risk factors in rural areas of Anhui Province of China. Eleven counties were randomly selected in Anhui Provi...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-013-2902-1
更新日期：2014-03-01 00:00:00
abstract：:Several chronic inflammatory disorders, such as rheumatoid arthritis and systemic lupus erythematosus, are associated with an increased risk of coronary artery disease (CAD) as a result of accelerated atherosclerosis. However, the data on CAD risk of polymyalgia rheumatica (PMR), one of the most common chronic inflamm...
journal_title：Rheumatology international
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00296-016-3557-5
更新日期：2017-01-01 00:00:00
abstract：:Adult-onset Still's disease (AOSD) is known as a systemic inflammatory disease of unknown etiology and pathogenesis, characterized by fever, skin eruptions, systemic organ involvement, and arthralgias. AOSD is difficult to diagnose because of its heterogeneous clinical manifestations and prevalence (although more prev...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-1991-y
更新日期：2012-08-01 00:00:00
abstract：:Serum deoxyribonuclease I (DNase I) activity in systemic lupus erythematosus (SLE) patients was shown to be lower than that of healthy laboratory personnel, rheumatoid arthritis, and scleroderma patients (P less than 0.001). The decrease in DNase I activity in SLE sera was not due to the effect of various autoantibodi...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00541153
更新日期：1981-01-01 00:00:00
abstract：:Rheumatology has its roots in ancient Greece. Hippocrates and other prominent Greek (Hellenes) physicians in ancient times, Hellenistic, Roman, and Byzantine period were acute observers of disease course and of patients and were able to define many disorders. They wrote books on various aspects of medicine and these w...
journal_title：Rheumatology international
pub_type： 历史文章,杂志文章,评审
doi：10.1007/s00296-019-04261-4
更新日期：2019-06-01 00:00:00
abstract：:Currently, many studies have focused on the possibility of using mean platelet volume (MPV) as a biomarker for disease activity in patients with systemic lupus erythematosus (SLE). To derive a more accurate estimation, a meta-analysis was conducted. Embase, PubMed, The Cochrane Library database and several Chinese dat...
journal_title：Rheumatology international
pub_type： 杂志文章,meta分析
doi：10.1007/s00296-018-4065-6
更新日期：2018-09-01 00:00:00
abstract：:The current clinical and laboratory parameters of Takayasu arteritis (TA) are insufficient for proper assessment of disease activity. The aims of this study were to investigate the markers of endothelial injury and repair, including circulating endothelial cell (CEC), circulating endothelial progenitor cell (CEPC) and...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-013-2937-3
更新日期：2014-08-01 00:00:00
abstract：:Systemic lupus erythematosus (SLE) affects women of childbearing age. To optimize fetal and maternal outcomes, effective reproductive health counseling is crucial. To analyze the effectiveness of reproductive health counseling in women with SLE and identify gaps in patient educational needs. Cross-sectional study incl...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-020-04671-9
更新日期：2021-02-01 00:00:00
abstract：:Abstract A 66-year-old woman showing renal dysfunction with elevated serum alkaline phosphatase and anti-SS-A antibody was admitted. A labial salivary gland biopsy showing infiltration of mononuclear cells and positive anti-SS-A antibody with sicca symptoms led to a diagnosis of primary Sjögren’s syndrome (SS). Fancon...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-0924-5
更新日期：2009-12-01 00:00:00
abstract：:Tumor necrosis factor (TNF) antagonists are among the most effective therapies for rheumatoid arthritis (RA), yet not all patients show a response. Using meta-analysis, this present study was designed to investigate whether or not the TNF-alpha promoter -308 A/G polymorphism is associated with responsiveness to anti-T...
journal_title：Rheumatology international
pub_type： 杂志文章,meta分析
doi：10.1007/s00296-006-0175-7
更新日期：2006-12-01 00:00:00
abstract：:Omentin is an adipokine that reportedly protects against cardiometabolic risk. We investigated the relationships between omentin concentrations and subclinical cardiovascular disease in rheumatoid arthritis (RA). Omentin concentrations were measured in 213 (104 black; 109 white) RA patients. Relationships of omentin l...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-016-3541-0
更新日期：2017-01-01 00:00:00
abstract：:Osteoporosis has become an increasingly recognized complication among patients with chronic liver disease (CLD). The aim of the present study was to assess the prevalence and risk factors of osteoporosis in patients with CLD (primary biliary cirrhosis and chronic viral hepatitis B or C patients) in comparison with a g...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-1071-8
更新日期：2010-05-01 00:00:00
abstract：:Hand osteoarthritis (OA) is a common degenerative joint disorder leading to substantial pain and disability. The most severe subtype is erosive hand OA characterized by an abrupt onset, local inflammation, subchondral erosions and worse outcomes than non-erosive disease. Biomarkers of hand OA could help to diagnose th...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-017-3864-5
更新日期：2018-05-01 00:00:00
abstract：:The objective of the study was to evaluate synovial tissue receptor activator of nuclear factor-κβ ligand (RANKL) and osteoprotegerin (OPG) as biomarkers of disease activity, progressive joint damage, and therapeutic response, during cytokine blockade in rheumatoid arthritis (RA). Patients with active RA entered a ran...
journal_title：Rheumatology international
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00296-009-1191-1
更新日期：2010-11-01 00:00:00
abstract：:Ankylosing spondylitis (AS) is an autoimmune spondyloarthropathy involving principally the sacroiliac joint and axial skeleton. Spinal cord involvement is an infrequent and late complication. It mostly results from compressive myelopathy due to skeletal osteopathy and usually presents with radiculomyelopathic sensory ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1614-z
更新日期：2011-07-01 00:00:00
abstract：:The aim of the study was to assess agreement between three-dimensional volumetric ultrasound (3D US) performed by inexperienced staff and real-time conventional ultrasound (2D US) performed by experienced rheumatologists in detecting and scoring rheumatoid arthritis (RA) lesions. Thirty-one RA patients underwent exami...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-016-3606-0
更新日期：2017-02-01 00:00:00
abstract：:The efficacy and tolerability of aceclofenac (100 mg bid; n = 109), a new non-steroidal anti-inflammatory agent, was compared to that of indomethacin (50 mg bid; n = 110) in a multi-centre, 12-week, randomized, double-blind clinical trial in patients with rheumatoid arthritis. The efficacy of aceclofenac, on the basis...
journal_title：Rheumatology international
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF00290375
更新日期：1996-01-01 00:00:00
