Abstract：
:In this cross-sectional study a comparison was made of rheumatoid factor (RF) isotypes in 203 RF positive patients with arthritis. Of these, 129 had rheumatoid arthritis (RA) and 74 a milder disease that would formerly have been classified as probable RA. The majority (74%) of the RA patients had elevations of two or three RF isotypes compared with only 34% of the patients with the milder form of arthritis. A striking feature was that combined elevation of IgM RF and IgA RF was found in 67% of the RA patients compared to only 20% of the patients with milder arthritis who most frequently had an isolated elevation of IgM RF (41%). RA patients with an isolated elevation of IgA RF were younger and had a shorter disease history than RA patients with an isolated elevation in IgM RF or a combined elevation of IgA RF and IgM RF. The prevalence of raised IgM RF was, furthermore, found to increase with age and disease duration. We conclude that a raised level of IgA RF is an adverse phenomenon in patients with seropositive arthritis while patients with an isolated increase in IgM RF may be expected to experience a relatively mild disease course.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Jónsson T,Valdimarsson Hdoi
10.1007/BF00290265subject
Has Abstractpub_date
1992-01-01 00:00:00pages
111-3issue
3eissn
0172-8172issn
1437-160Xjournal_volume
12pub_type
杂志文章abstract：:Adult-onset Still's disease (AOSD) is known as a systemic inflammatory disease of unknown etiology and pathogenesis, characterized by fever, skin eruptions, systemic organ involvement, and arthralgias. AOSD is difficult to diagnose because of its heterogeneous clinical manifestations and prevalence (although more prev...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-1991-y
更新日期：2012-08-01 00:00:00
abstract：:The main objective of this study was to assess the symptoms and functional difficulties caused by rheumatoid arthritis through application of the willingness to pay (WTP) method. Structured questionnaire study was conducted among 242 RA patients. The subjects were asked to evaluate their functional capacity using visu...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-1280-1
更新日期：2011-03-01 00:00:00
abstract：OBJECTIVE:The aim was to evaluate the efficacy and safety of multiple infusions with achimeric, anti-tumor necrosis factor (TNF)alpha monoclonal antibody (infliximab) in patients with psoriatic arthritis (PsA) and psoriasis vulgaris. METHODS:Over 22 weeks, nine patients with both active psoriasis and PsA received five...
journal_title：Rheumatology international
pub_type： 临床试验,杂志文章
doi：10.1007/s00296-002-0246-3
更新日期：2002-11-01 00:00:00
abstract：:We report a 34-year-old female case of diffuse systemic sclerosis (SSc) with generalized ectopic calcification, who developed severe headache with vertical atlantoaxial subluxation (AAS) complicated by calcification around the odontoid process (crowned dens pattern calcification). Although a rare complication, AAS sho...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1703-z
更新日期：2011-09-01 00:00:00
abstract：:A community-based cohort comprising 150 patients with recent-onset seropositive arthritis or seronegative oligoarthritis or polyarthritis was monitored for 8 years. Of the different rheumatoid factor (RF) tests, the initial positivity in the most sensitive assays (latex slide test and IgM-RF by enzyme immunoassay) was...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00541346
更新日期：1988-01-01 00:00:00
abstract：:When rheumatoid articular cartilage samples were incubated with normal peripheral blood monocytes and cultured synovial cells in the presence of recombinant human interleukin-1 (IL-1) in vitro, large numbers of monocytes were seen to be attached to the articular surface. Significant numbers of monocytes invaded the ca...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00290248
更新日期：1991-01-01 00:00:00
abstract：:Activated T lymphocytes (Ia+ T-cells) in peripheral blood are associated with immune stimulation. We found the percentages of these cells significantly increased in 95% of rheumatoid arthritis (RA) patients. Our studies showed no relation between the percentages of these cells in peripheral blood and concurrent erythr...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00272435
更新日期：1988-01-01 00:00:00
abstract：:Tuberculosis (TB) is an important preventable infection in patients with rheumatoid arthritis (RA). To determine the risk of TB in patients with RA by comparing with those with non-specific back pain (NSBP), and to identify the risk factors in the RA group. Medical data were retrieved from a centralized electronic dat...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-020-04583-8
更新日期：2020-06-01 00:00:00
abstract：:The aim was to evaluate the relative importance of the 20 functions assessed by patients to produce the Health Assessment Questionnaire's Disability Index (HAQ-DI). A systematic sample of 242 rheumatoid arthritis patients was drawn. Altogether 179 subjects returned acceptably filled questionnaire including perceived r...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-1176-0
更新日期：2010-09-01 00:00:00
abstract：:The aim of this study was to compare clinical symptoms, perceived health status, health resource use and psychosocial features in fibromyalgia (FM) patients at different health care levels. A total of 315 participants were recruited from primary care (PC) (n=101) and rheumatology settings (RS) (n=214). Subjects comple...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-008-0818-y
更新日期：2009-08-01 00:00:00
abstract：OBJECTIVES:We aimed to assess the clinical significance of Krebs von den Lungen-6 (KL-6) in the diagnosis and severity of interstitial lung disease (ILD) in a French cohort of patients with systemic sclerosis (SSc). METHODS:Serum KL-6 concentrations were measured with chemiluminescent enzyme immunoassay (CLEIA) in 75 ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-018-3987-3
更新日期：2018-05-01 00:00:00
abstract：:The main goal of this project was to identify the presence of fibromyalgia (FM) subgroups using a simple and frequently used clinical tool, the Fibromyalgia Impact Questionnaire (FIQ). A total of 61 women diagnosed with FM participated in this study. FM subgroups were created by applying a hierarchical cluster analysi...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-008-0722-5
更新日期：2009-03-01 00:00:00
abstract：:We have prepared antibody/3H-dsDNA immune complexes and have used three independent radioimmunoassays to quantitate their interaction with complement; the solution phase C1q assay, the Raji cell assay, and a complement-based red blood cell adherence assay (RBC-CF). Our results indicate that although there is reasonabl...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00541220
更新日期：1981-01-01 00:00:00
abstract：:Acute leukemia is uncommonly seen with rheumatoid arthritis during or following treatment with low-dose methotrexate, a safe and effective treatment for the arthritic condition. We describe here a 68-year-old woman with rheumatoid arthritis who developed acute erythroleukemia during low-dose methotrexate therapy (tota...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-004-0502-9
更新日期：2005-05-01 00:00:00
abstract：:A previously healthy 40-year-old woman presented as unstable angina. She had a family history of stroke as the only cardiovascular risk factor. Her blood pressure on admission was 150/90 mmHg. Laboratory study showed absolutely all negative markers of inflammation, autoimmune disorders, or atherosclerosis. Coronary an...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-008-0739-9
更新日期：2009-04-01 00:00:00
abstract：:Clinical presentation of fibromyalgia syndrome (FMS) is heterogeneous and often involves psychological comorbidities. Clinical subgrouping of FMS patients has been proposed as a strategy to improve patients' long-term outcomes by helping identify specific treatment needs. Using the 90 Symptom Checklist Revised (SCL-90...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-2199-x
更新日期：2012-11-01 00:00:00
abstract：:The atrioventricular conduction time (P-R interval) was determined in 189 women and 90 men with rheumatoid arthritis (RA). Only three women and one man were found to have pathological prolongation of the P-R interval. However, a significant prolongation of the P-R interval, within normal range, was seen in women with ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00541337
更新日期：1985-01-01 00:00:00
abstract：:The effect of knee OA on kinetic and kinematic parameters during walking and standing is still controversial. Stability and energy consumption have not been well investigated in patients with OA. This research investigated the parameters distinguishing between the healthy subjects and patients with OA performance. It ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-012-2639-2
更新日期：2013-07-01 00:00:00
abstract：:Anaemia of chronic disease (ACD) is a common extra-articular manifestation of rheumatoid arthritis (RA). Tumour necrosis factor alpha (TNF alpha) plays an important role in the development of ACD. The objective of the present study was to assess inhibition of in vitro colony-forming unit erythrocyte (CFUe) and blast-f...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00300811
更新日期：1994-01-01 00:00:00
abstract：:Crystalglobulinemia is an extremely rare pathology that is associated in most cases with plasma cell dyscrasia, mainly multiple myeloma. In most cases, it may be the manifestation of incipient gammopathy or it manifests shortly after diagnosis. We report a patient with ischemic lesions of thrombotic origin in lower li...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-020-04620-6
更新日期：2020-08-01 00:00:00
abstract：:Anti-TNF drugs may increase lymphoma risk in autoimmune rheumatic diseases, such as rheumatoid arthritis, but there have been no reports stating increased risk of lymphoma in ankylosing spondylitis (AS). Before 2 years, we had presented a case with AS developing Hodgkin's lymphoma following 6 months of etanercept trea...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-1265-0
更新日期：2011-12-01 00:00:00
abstract：:Familial Mediterranean fever is a chronic inflammatory disease characterized by periodic and self-limited episodes of fever and aseptic polyserositis. Although colchicine treatment has altered the course of the disease, it is believed that subclinical inflammation is still present, leading to endothelial dysfunction a...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-019-04457-8
更新日期：2020-01-01 00:00:00
abstract：:We sought to determine the prevalence of additional connective tissue diseases (CTDs) in patients with idiopathic inflammatory myopathies (IIM), and to study the muscle biopsy patterns in various clinico-serologic subsets of myositis. We undertook a retrospective cohort study of 648 patients with a histological diagno...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-019-04411-8
更新日期：2019-10-01 00:00:00
abstract：:We investigated the overall frequency of anti-phospholipid syndrome (APS) occurrence in Korean patients with consecutively detected anti-phospholipid antibodies with an interval of 12 weeks (persistent aPLs). We retrospectively reviewed the results of blood tests of aPLs in 14,889 patients in whom aPL tests were perfo...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-019-04318-4
更新日期：2019-08-01 00:00:00
abstract：:We report our experience and hypothesis on the diagnosis and treatment of patients with vasculitis who are simultaneously diagnosed with serum-positive cytomegalovirus (CMV) immunoglobulin (Ig)M antibodies and negative CMV DNA polymerase chain reaction (PCR). It remains unknown how to treat this kind of "phantom" CMV ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-004-0522-5
更新日期：2005-10-01 00:00:00
abstract：:We report a case of a 39-year-old female with active systemic lupus erythematosus who complained of lethargy and weakness with a moderate renal impairment. Hypercalcemia was confirmed by laboratory examination. Her X-ray revealed significant ectopic calcinosis in subcutaneous tissue of bilateral hands, and Tc-99(m) me...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-016-3486-3
更新日期：2016-07-01 00:00:00
abstract：:Anemia is common with connective tissue disorders, but pancytopenia is rare. We report a 22-year-old female who presented with menorrhagia, seizures, anemia, leukocytosis, thrombocytopenia, pericardial effusion, positive ANA, and evidence of vasculitis on CT head scan and was diagnosed with systemic lupus erythematosu...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-003-0318-z
更新日期：2004-01-01 00:00:00
abstract：UNLABELLED:The objective of this study is to provide a critical overview of available instruments to assess impairments in patients with rheumatic disorders, and to recommend reliable and valid instruments for use in allied health care and rehabilitation medicine. A computer-aided literature search (1982-2004) in sever...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-005-0603-0
更新日期：2005-09-01 00:00:00
abstract：:We studied the relationships between physician-assessed damage, severity and activity in a large, multicentre systemic sclerosis (SSc, scleroderma) cohort. We hypothesized that there is a relationship between disease activity and severity and damage, but that severity would be more strongly related to damage. A total ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-1129-7
更新日期：2010-07-01 00:00:00
abstract：:We report a case of visceral leishmaniasis in a patient from northern Norway with psoriatic arthritis treated with a combination of etanercept and methotrexate. The patient resided extensively in southern Spain, a zone endemic for leishmania. ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-012-2483-4
更新日期：2013-10-01 00:00:00
