Relative importance of the functional abilities comprising Health Assessment Questionnaire Disability Index among rheumatoid arthritis patients.


:The aim was to evaluate the relative importance of the 20 functions assessed by patients to produce the Health Assessment Questionnaire's Disability Index (HAQ-DI). A systematic sample of 242 rheumatoid arthritis patients was drawn. Altogether 179 subjects returned acceptably filled questionnaire including perceived rheumatoid arthritis status in the 20 functions comprising the HAQ-DI. A separate complementary questionnaire was sent to 80 randomly chosen subjects. They were asked to estimate how important each of the same 20 items were in their everyday life using the VAS method. Completely answered complementary questionnaires were returned by 66 (88%) of the subsample. The relative importance of the functions assessed varied considerably. Men assessed the highest importance to the ability to walk outdoors on flat ground and women to dressing themselves, getting in and out of bed and washing and drying their body. For both genders the least important function was the ability to take a tub bath. The importance of all other functions except taking a tub bath was positively highly significantly correlated with the importance of each of the other functions. Factor analyses with one factor model showed high loadings on most functions, with the exception of 'Take a tub bath'. The two-factor model formed one factor with loadings concentrating slightly more on 'lower extremity' and another on 'upper extremity'. Assessment of RA patients' functional status would benefit from further development of measures by giving relative weights from patients' perspective to those functional abilities which are used for index computations.


Rheumatol Int


Tuominen R,Möttönen T,Suominen C,Vahlberg T,Tuominen S




Has Abstract


2010-09-01 00:00:00












  • Ankylosing spondylitis in a patient with myelodysplastic syndrome: an association with HLA-B27 or coincidence?

    abstract::The authors report an unusual case of myelodysplastic syndrome (MDS) associated with ankylosing spondylitis (AS). A 40-year-old-man with MDS presented with chronic low back pain for 6 years. Four years ago, MDS was diagnosed during routine blood analysis for the work-up of his articular complaints. His initial articul...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Lee J,Kim H,Ahn JK,Hwang JW,Jang JH,Koh EM,Cha HS

    更新日期:2009-04-01 00:00:00

  • Failure of the serological determination of HLA-B27 due to antigen masking in patients with ankylosing spondylitis.

    abstract::In patients suffering from ankylosing spondylitis (AS) HLA-B27 determination by means of the microlymphocytotoxicity test (MLCT) sometimes gives equivocal or false-negative results even though it has been performed with meticulous care. These failures of the test did not arise when the isolated mononuclear cells (MNC)...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Neumüller J,Fischer M,Eberl R

    更新日期:1993-01-01 00:00:00

  • Acute pseudogout of the neck--the crowned dens syndrome: 2 case reports and review of the literature.

    abstract::Acute pseudogout of the neck, also known as the crowned dens syndrome, is a rare cause of neck pain characterised by crystalline deposition in periodontoid articular tissues. It is typified clinically by severe cervical pain and stiffness, often in conjunction with pyrexia and raised inflammatory markers. As such, it ...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审


    authors: Siau K,Lee M,Laversuch CJ

    更新日期:2011-01-01 00:00:00

  • Serum levels of interleukin 1-beta, tumor necrosis factor-alpha, soluble interleukin 2 receptor and soluble CD8 in seronegative spondylarthropathies.

    abstract::Seronegative spondylarthropathies are disorders with the same predisposing antigen, namely HLA B27, a class I molecule of the HLA system. The mechanisms of the different diseases are unknown, and there is no proof of immune system participation. We have investigated patients with spondylarthropathies in order to searc...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Toussirot E,Lafforgue P,Boucraut J,Despieds P,Schiano A,Bernard D,Acquaviva PC

    更新日期:1994-01-01 00:00:00

  • Serum serotonin levels and bone in rheumatoid arthritis patients.

    abstract::In rheumatoid arthritis (RA), a disease characterized by bone loss, increased levels of serotonin have been reported. Recent studies have demonstrated a role for circulating serotonin as a regulator of osteoblastogenesis, inhibiting bone formation. Thus, we measured serum serotonin levels (SSL) in a Portuguese sample ...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Bernardes M,Vieira T,Lucas R,Pereira J,Costa L,Simões-Ventura F,Martins MJ

    更新日期:2017-11-01 00:00:00

  • Cryoglobulins in cases of rheumatoid arthritis.

    abstract::Clinically diagnosed cases with different grades of rheumatoid arthritis (RA) were studied for (a) cryoglobulin content (b) constituents of cryoglobulins, and (c) rheumatoid factor (RF) titers in sera and cryoglobulins. Of 60 patients, 28 (46.66%) had significantly high levels of cryoglobulins and were mainly distribu...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Chattopadhya D,Ravindran B,Prakash K

    更新日期:1985-01-01 00:00:00

  • Rheumatoid arthritis masquerading as acromegaly recurrence: report of two cases.

    abstract::Acromegaly is a chronic endocrinopathy characterized by hypersecretion of growth hormone (GH) and consequently of insulin-like growth factor-1 (IGF-1). The arthropathy in acromegaly is the most frequent and important cause of morbidity and functional disability in acromegaly. Rheumatoid arthritis (RA) is a rarely repo...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Aydın Y,Coşkun H,Kır S,Yazici S,Kudaş Ö,Güngör A

    更新日期:2012-09-01 00:00:00

  • Plasma leptin and neuropeptide Y concentrations in patients with rheumatoid arthritis treated with infliximab, a TNF-α antagonist.

    abstract::TNF-α is one of the key proinflammatory cytokines in pathogenesis of rheumatoid arthritis (RA). TNF-α was also found to enhance synthesis of leptin. Leptin is mainly adipocyte-derived hormone controlling appetite and energy expenditure. It acts through inhibition of neuropeptide Y secretion. It is possible that TNF-α-...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Kopec-Medrek M,Kotulska A,Widuchowska M,Adamczak M,Więcek A,Kucharz EJ

    更新日期:2012-11-01 00:00:00

  • Increased plasma levels of IL-21 and IL-23 in spondyloarthritis are not associated with clinical and MRI findings.

    abstract::We have investigated the role of the Th17-related cytokines interleukin-17A (IL-17A), IL-21, and IL-23 in spondyloarthritis (SpA) by examining their association with disease activity and magnetic resonance imaging (MRI) findings in patients with SpA (n = 80). Furthermore, to investigate the cellular origins of the cyt...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Andersen T,Rasmussen TK,Hvid M,Holm CK,Madsen KJ,Jurik AG,Hokland M,Stengaard-Pedersen K,Schiøttz-Christensen B,Deleuran B

    更新日期:2012-02-01 00:00:00

  • Anti-IL-17 therapy in treatment of rheumatoid arthritis: a systematic literature review and meta-analysis of randomized controlled trials.

    abstract::IL-17 has a role in inflammation in RA, and its levels in joints correlate with disease severity. Multiple RCTs have been performed to study effects of anti-IL-17 agents. The objective of this study was to perform a systematic review and meta-analysis to analyze the efficacy and safety of anti-IL-17 agents in the mana...

    journal_title:Rheumatology international

    pub_type: 杂志文章,meta分析,评审


    authors: Kunwar S,Dahal K,Sharma S

    更新日期:2016-08-01 00:00:00

  • C-reactive protein-mediated complement activation in polymyalgia rheumatica and other systemic inflammatory diseases.

    abstract::An immunoglobulin-independent deposition of the complement (C) components C4 and C3 occurs on rat kidney medullary structures, when sera of patients with various inflammatory diseases are studied by indirect immunofluorescence. The diagnostic value of this new test (C4-C3-IFT) for polymyalgia rheumatica (PMR) is stres...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Vaith P,Hänsch GM,Peter HH

    更新日期:1988-01-01 00:00:00

  • Dilemma in management of hemorrhagic myositis in dermatomyositis.

    abstract::Dermatomyositis (DM) is a rare inflammatory disorder affecting the muscle and skin. DM patients can present with spontaneous muscle hemorrhage, a potentially fatal complication. The best practice for management of hemorrhagic myositis in these patients remains unclear. Here we discuss the case of a patient who present...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审


    authors: Chandler JM,Kim YJ,Bauer JL,Wapnir IL

    更新日期:2020-02-01 00:00:00

  • The use of 'alternative treatments' by patients with rheumatoid arthritis.

    abstract::In a study of 199 patients with rheumatoid arthritis, 68% were found to have tried 'alternative treatments'. Some treatments (acupuncture and faith healing) gave subjective benefit in nearly half those who tried them and were considered to be better than others (such as copper bracelets). No adverse reactions were rep...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Struthers GR,Scott DL,Scott DG

    更新日期:1983-01-01 00:00:00

  • Early arthritis clinic is effective for rheumatoid and psoriatic arthritides.

    abstract:INTRODUCTION:Early arthritis clinics (EACs) have been well established since 1980s. Most of the data for their effectiveness comes from rheumatoid arthritis (RA) management and is largely limited to process outcomes. There is little evidence that such clinics improve clinical outcomes particularly for psoriatic arthrit...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Nisar MK

    更新日期:2019-04-01 00:00:00

  • Serologic response to Epstein-Barr virus antigens in patients with systemic lupus erythematosus: a controlled study.

    abstract::Previous studies showed a link between systemic lupus erythematosus (SLE) and Epstein-Barr virus (EBV) infection. We sought to determine the features of serologic response to EBV in SLE patients and whether this response differs from those of systemic sclerosis (SSc) and primary antiphospholipid syndrome (PAPS) patien...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Esen BA,Yılmaz G,Uzun S,Ozdamar M,Aksözek A,Kamalı S,Türkoğlu S,Gül A,Ocal L,Aral O,Inanç M

    更新日期:2012-01-01 00:00:00

  • Ultrasound scans and dual energy CT identify tendons as preferred anatomical location of MSU crystal depositions in gouty joints.

    abstract:OBJECTIVE:The present study was performed to localize the articular deposition of monosodium urate (MSU) crystal in joints. We compare the detection efficiencies of dual-energy CT (DECT) and ultrasound scans. METHODS:Analyses by DECT and ultrasound were performed with 184 bilateral joints of the lower limbs of 54 cons...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Yuan Y,Liu C,Xiang X,Yuan TL,Qiu L,Liu Y,Luo YB,Zhao Y,Herrmann M

    更新日期:2018-05-01 00:00:00

  • Sites of inflammation in painful rheumatoid shoulder assessed by musculoskeletal ultrasound and power Doppler sonography.

    abstract::Ultrasonography (US) and power Doppler sonography (PDS) was used to investigate causes of new onset of shoulder pain and sites of shoulder inflammation in 157 shoulders of 99 patients with rheumatoid arthritis (RA). US detected effusion and/or synovitis in 92/157 glenohumeral joints, subdeltoid bursitis in 56/157 shou...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Stegbauer J,Rump LC,Weiner SM

    更新日期:2008-03-01 00:00:00

  • Family history of ochronotic arthropathy.

    abstract::Alkaptonuria is a rare autosomal-recessive disorder that produces accumulation of homogentisic acid in body fluids. The accumulation in collagen tissues, mainly in the joint cartilage, produces ochronotic arthropathy. We report two clinical cases of one brother and sister with alkaptonuria and ochronotic arthropathy d...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审


    authors: Gómez-Lechón Quirós L,Hidalgo Calleja C,Acosta de la Vega ME,Compán Fernández O,Pastor Navarro S,Montilla Morales C

    更新日期:2020-07-08 00:00:00

  • Clinical presentation, treatment and outcome of Takayasu's arteritis in southern Chinese: a multicenter retrospective study.

    abstract::To study the clinical presentation, treatment and outcome of southern Chinese patients with Takayasu's arteritis (TA). This is a retrospective chart review study of 78 patients managed in 14 public hospitals in Hong Kong between the years 2000 and 2010. Patients were identified from the hospital registry using the ICD...

    journal_title:Rheumatology international

    pub_type: 杂志文章,多中心研究


    authors: Wong SPY,Mok CC,Lau CS,Yip ML,Tam LS,Ying KY,Ng WL,Ng KH,Leung MH,Lee TY,To CH,Lee KL,Wan MC,Yu KL,Wong PCH,Sung CK,Lee KF,Kun EWL,Hong Kong Takayasu’s arteritis study group.

    更新日期:2018-12-01 00:00:00

  • The classification of fibromyalgia syndrome.

    abstract::As has been shown by a number of working groups, primary fibromyalgia syndrome does not represent a single clinical entity. It is possible to distinguish between a subgroup with high pain sensitivity and no associated psychiatric condition, a second and a third subgroup characterized by depression associated with fibr...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审


    authors: Müller W,Schneider EM,Stratz T

    更新日期:2007-09-01 00:00:00

  • Prevalence and factors associated with disturbed sleep in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis: a systematic review.

    abstract::This review explores the prevalence and factors associated with disturbed sleep for patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis in order to clarify consistent findings in this otherwise disparate research field. The association of physical, demographic and psychological factors co...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审


    authors: Leverment S,Clarke E,Wadeley A,Sengupta R

    更新日期:2017-02-01 00:00:00

  • Intracellular calcium responses to cholinergic stimulation of lymphocytes from healthy donors and patients with rheumatoid arthritis.

    abstract::This study was performed to identify the role of cholinergic stimulation on changes of intracellular calcium concentrations as intracellular messenger of neuroimmune interaction. Incubation of PBMC with acetylcholine (ACh) leads to Ca(2+) oscillations in healthy controls. PBMC from rheumatoid arthritis (RA) patients e...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Nast A,Malysheva O,Krause A,Wahle M,Baerwald CG

    更新日期:2009-03-01 00:00:00

  • Macrophage activation syndrome in children with systemic juvenile idiopathic arthritis and systemic lupus erythematosus.

    abstract::Macrophage activation syndrome (MAS) is a hyper-inflammatory disorder secondary to a rheumatic disease such as systemic juvenile idiopathic arthritis (SJIA) and systemic lupus erythematosus (SLE). We aimed to present the characteristics of our pediatric MAS patients. Clinical features, laboratory parameters, treatment...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Aytaç S,Batu ED,Ünal Ş,Bilginer Y,Çetin M,Tuncer M,Gümrük F,Özen S

    更新日期:2016-10-01 00:00:00

  • Free radicals and antioxidants in primary fibromyalgia: an oxidative stress disorder?

    abstract::The role of free radicals in fibromyalgia is controversial. In this study, 85 female patients with primary fibromyalgia and 80 age-, height-, and weight-matched healthy women were evaluated for oxidant/antioxidant balance. Malondialdehyde is a toxic metabolite of lipid peroxidation used as a marker of free radical dam...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Bagis S,Tamer L,Sahin G,Bilgin R,Guler H,Ercan B,Erdogan C

    更新日期:2005-04-01 00:00:00

  • Crystalglobulinemia manifested as acute renal failure and thrombotic vasculopathy.

    abstract::Crystalglobulinemia is an extremely rare pathology that is associated in most cases with plasma cell dyscrasia, mainly multiple myeloma. In most cases, it may be the manifestation of incipient gammopathy or it manifests shortly after diagnosis. We report a patient with ischemic lesions of thrombotic origin in lower li...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审


    authors: Gómez-Lechón Quirós L,Acosta De La Vega ME,Compán Fernández O,Pastor Navarro S,Montilla Morales C,Moyano Bueno D,Martín Centellas J,Santos-Briz Terrón A,Hidalgo Calleja C

    更新日期:2020-08-01 00:00:00

  • Defining functioning categories in axial Spondyloarthritis: the role of the ASAS Health Index.

    abstract::The Assessment of SpondyloArthritis international Society Health Index (ASAS HI) is an inclusive questionnaire, able to describe the total impairments and restrictions due to axial spondyloarthritis (axSpA). Considering the relationship between ASAS HI and the Ankylosing Spondylitis Disease Activity Score (ASDAS)-CRP,...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Di Carlo M,Lato V,Di Matteo A,Carotti M,Salaffi F

    更新日期:2017-05-01 00:00:00

  • Human papillomavirus and chlamydia trachomatis infections in rheumatoid arthritis under anti-TNF therapy: an observational study.

    abstract::The objective of this study was to evaluate human papillomavirus (HPV) and Chlamydia trachomatis (CT) infections in RA patients pre- and post-TNF blocker. Fifty female RA patients (ACR criteria), who were eligible to anti-TNF therapy [n = 50 at baseline (BL) and n = 45 after 6 months of treatment (6 M)], and 50 age-ma...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Waisberg MG,Ribeiro AC,Candido WM,Medeiros PB,Matsuzaki CN,Beldi MC,Tacla M,Caiaffa-Filho HH,Bonfa E,Silva CA

    更新日期:2015-03-01 00:00:00

  • Lung involvement in patients with primary Sjögren's syndrome: what are the predictors?

    abstract::The aim of this study was to investigate the prevalence, predictors and radiological findings of primary Sjögren's syndrome (pSS)-associated lung involvement. This retrospective cohort study included 123 patients with demographic, clinical, laboratory and radiological data who were diagnosed with pSS. Lung involvement...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Yazisiz V,Arslan G,Ozbudak IH,Turker S,Erbasan F,Avci AB,Ozbudak O,Terzioglu E

    更新日期:2010-08-01 00:00:00

  • Demographic and clinical features of gout patients in Turkey: a multicenter study.

    abstract::Gout results from multifactor interactions between gender, age, genetic and environmental factors. Environmental factors underlying gout and precipitating factors triggering acute attacks might vary in different populations with different lifestyles. In this study, we aimed to collect data regarding the demographic an...

    journal_title:Rheumatology international

    pub_type: 杂志文章,多中心研究


    authors: Öztürk MA,Kaya A,Şenel S,Dönmez S,Balkarlı A,Çobankara V,Erhan Ç,Sayarlıoğlu M,Ugan Y,Tunç ŞE,Pehlivan Y,Kısacık B,Tufan A,Onat AM,Tezcan E,Yıldırım Çetin G,Pamuk ON

    更新日期:2013-04-01 00:00:00

  • Total oxidative/anti-oxidative status and relation to bone mineral density in osteoporosis.

    abstract::The aim of this study was to evaluate the total antioxidant status (TAS), total oxidative status (TOS) and oxidative stress index (OSI) in patients with postmenopausal osteoporosis. We also investigate the relation between bone mineral density and oxidative/antioxidative parameters. Thirty-nine patients with osteoporo...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Altindag O,Erel O,Soran N,Celik H,Selek S

    更新日期:2008-02-01 00:00:00