Abstract：
:We assess the usefulness of 99mTc-pertechnetate hand perfusion scintigraphy in patients with Raynaud's phenomenon (RP). The study population consisted of 18 patients with primary RP, 25 patients with secondary RP within systemic sclerosis (SSc), and ten healthy individuals. Gamma camera dynamic first-pass study during the first 60 s and a static scintigraphy after 5 min were recorded following a bolus injection of 99mTc-pertechnetate via a cubital vein. Regions of interest were drawn on the summed images around the fingers and the palmar region. The fingers-to-palm ratios were then calculated. The mean fingers-to-palm ratio for dynamic study (blood flow) was 0.58 ± 0.19 for the healthy group, 0.45 ± 0.18 for the primary RP, and 0.43 ± 0.21 for the SSc patients. The mean fingers-to-palm ratio for static study (blood pool) was 0.44 ± 0.06 for the healthy group, 0.42 ± 0.06 for the primary RP, and 0.36 ± 0.07 for the SSc patients. Analysis of variance showed these differences to be significant (p = 0.039 from blood flow and p = 0.004 from blood pool). The receiver operating characteristic curve showed sensitivity of 80% and a specificity of 60% when using cutoff values of 0.40 for blood flow and sensitivity of 79% and a specificity of 70% when using cutoff values of 0.37 for blood pool. Our method is able to differentiate between patients with normal and those with abnormal microcirculation of the hands. Dynamic study separates the healthy subjects from patients with RP, while static study separates primary from secondary RP.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Pavlov-Dolijanovic S,Petrovic N,Vujasinovic Stupar N,Damjanov N,Radunovic G,Babic D,Sobic-Saranovic D,Artiko Vdoi
10.1007/s00296-016-3584-2subject
Has Abstractpub_date
2016-12-01 00:00:00pages
1683-1688issue
12eissn
0172-8172issn
1437-160Xpii
10.1007/s00296-016-3584-2journal_volume
36pub_type
杂志文章abstract：OBJECTIVE:The aim of this study was to evaluate the efficacy and tolerability of long-term treatment with cyclosporin A (CsA) in patients with psoriatic arthritis (PsA). METHODS:Sixty patients with PsA were enrolled in a prospective, nonrandomised study of CsA. Patients with hypertension or hypercreatinemia were exclu...
journal_title：Rheumatology international
pub_type： 临床试验,杂志文章
doi：10.1007/s00296-001-0166-7
更新日期：2002-04-01 00:00:00
abstract：:Several studies have shown a negative association between smoking and primary Sjögren's syndrome (pSS), and smoking may interfere with the immune response. The purpose of this study was to investigate if smoking affects disease activity and disease phenotype in pSS. In this cross-sectional study, consecutive pSS patie...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-019-04335-3
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abstract：:Acute pseudogout of the neck, also known as the crowned dens syndrome, is a rare cause of neck pain characterised by crystalline deposition in periodontoid articular tissues. It is typified clinically by severe cervical pain and stiffness, often in conjunction with pyrexia and raised inflammatory markers. As such, it ...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-009-1145-7
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abstract：:The present cross-sectional data demonstrate cardiovascular (CV) risk in patients with rheumatoid arthritis (RA). The cross-sectional data were part of an interventional trial that included 100 patients with defined RA. Traditional CV risk parameters and risk score calculation for the German population were used to as...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-2238-7
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abstract：:Vasculitides associated with anti-neutrophil cytoplasmic antibodies are heterogeneous, systemic, low prevalence and high morbidity and mortality entities. They include granulomatosis with polyangiitis, microscopic polyangiitis and eosinophilic granulomatosis with polyangiitis. In Latin America, there are few descripti...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-020-04631-3
更新日期：2020-08-01 00:00:00
abstract：:The American Rheumatism Association (ARA) clinical criteria have been tested in systemic lupus erythematosus (SLE), progressive systemic sclerosis, polyarteritis nodosa and polymyositis/dermatomyositis. Hospital admissions from a defined population over the same period were studied. Increased weighting of the scores f...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00541261
更新日期：1981-01-01 00:00:00
abstract：:The objectives of this study are to describe appropriateness and drug treatment of comorbidities in fibromyalgia (FM). Cross-sectional study of a group of patients. Number of drugs, indication, duration and appropriateness of prescriptions were evaluated. Patients were classified as: group 1, (FM/FM) previous FM diagn...
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journal_title：Rheumatology international
pub_type： 杂志文章
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journal_title：Rheumatology international
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doi：10.1007/s00296-014-3016-0
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journal_title：Rheumatology international
pub_type： 杂志文章,评审
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journal_title：Rheumatology international
pub_type： 杂志文章,评审
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journal_title：Rheumatology international
pub_type： 杂志文章,评审
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journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-002-0230-y
更新日期：2002-09-01 00:00:00
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journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-1237-4
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journal_title：Rheumatology international
pub_type： 杂志文章
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更新日期：1989-01-01 00:00:00
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journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1510-6
更新日期：2011-11-01 00:00:00
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journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-005-0033-z
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journal_title：Rheumatology international
pub_type： 杂志文章,多中心研究
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更新日期：2014-05-01 00:00:00
abstract：:A simple technique for fine-needle aspiration biopsy from the synovial membrane of arthritis knee joints preceded by lavage of the joint cavity is described. The procedure was atraumatic, well accepted, and could be performed on outpatients. Cells originating from the synovial membrane were obtained in 12 of 17 knees ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00272430
更新日期：1988-01-01 00:00:00
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journal_title：Rheumatology international
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journal_title：Rheumatology international
pub_type： 杂志文章,评审
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journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-014-3104-1
更新日期：2015-02-01 00:00:00
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journal_title：Rheumatology international
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journal_title：Rheumatology international
pub_type： 杂志文章
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更新日期：2019-03-01 00:00:00
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journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00541220
更新日期：1981-01-01 00:00:00
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journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00541153
更新日期：1981-01-01 00:00:00
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journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-008-0749-7
更新日期：2009-04-01 00:00:00
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journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-020-04679-1
更新日期：2021-02-01 00:00:00
abstract：:Osteoarthritis (OA) is the most common form of arthritis, resulting in substantial disability and economic burden worldwide. While its exact pathogenesis remains elusive, both in vitro and human population-based studies have merged to support the hypothesis that TGF-β/BMP-mediated signalling pathways play a role in th...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-015-3251-z
更新日期：2015-08-01 00:00:00
