Abstract:
:A 50-year-old man presented with a complaint of low-back pain and widespread joint pain for the previous 20 years. Conventional radiography revealed wide areas of calcification in the intervertebral discs and degenerative changes in the peripheral joints. A diagnosis of ochronosis was made by the observation of bluish-brown pigmentation in the nose and ears, dark urine colors following alkalization, and high levels of homogentisic acid in the urine. Ochronosis should be considered in the differential diagnosis of patients with chronic low-back pain regarding features of widespread calcification in the intervertebral discs at radiography and bluish-brown pigmentation in the nose and ears.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Capkin E,Karkucak M,Yayli S,Serdaroğlu M,Tosun Mdoi
10.1007/s00296-007-0381-ysubject
Has Abstractpub_date
2007-11-01 00:00:00pages
61-4issue
1eissn
0172-8172issn
1437-160Xjournal_volume
28pub_type
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