Comprehensive analysis of microRNA expression patterns in renal biopsies of lupus nephritis patients.


:MicroRNAs (miRNAs) are noncoding RNA molecules of 21-24 nt that regulate the expression of target genes in a post-transcriptional manner. Evidence indicates that miRNAs play essential roles in embryogenesis, cell differentiation, and pathogenesis of human diseases. This study describes a comparison between the miRNA profile of kidney biopsies from lupus nephritis (LN) patients and the controls, to develop further understanding of the pathogenesis of LN. Kidney biopsies were taken from five LN patients detected LN Class II and three normal controls. The miRNA microarray chip analysis identified 66 miRNAs differentially expressed in LN. The chip results were confirmed by QRT-PCR. This work indicates that miRNAs are potential diagnosis biomarkers and probable factors involved in the pathogenesis of LN.


Rheumatol Int


Dai Y,Sui W,Lan H,Yan Q,Huang H,Huang Y




Has Abstract


2009-05-01 00:00:00












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    abstract::This review explores the prevalence and factors associated with disturbed sleep for patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis in order to clarify consistent findings in this otherwise disparate research field. The association of physical, demographic and psychological factors co...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审


    authors: Leverment S,Clarke E,Wadeley A,Sengupta R

    更新日期:2017-02-01 00:00:00

  • Intracellular calcium responses to cholinergic stimulation of lymphocytes from healthy donors and patients with rheumatoid arthritis.

    abstract::This study was performed to identify the role of cholinergic stimulation on changes of intracellular calcium concentrations as intracellular messenger of neuroimmune interaction. Incubation of PBMC with acetylcholine (ACh) leads to Ca(2+) oscillations in healthy controls. PBMC from rheumatoid arthritis (RA) patients e...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Nast A,Malysheva O,Krause A,Wahle M,Baerwald CG

    更新日期:2009-03-01 00:00:00

  • Elevated plasma level of HMGB1 is associated with disease activity and combined alterations with IFN-α and TNF-α in systemic lupus erythematosus.

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Ma CY,Jiao YL,Zhang J,Yang QR,Zhang ZF,Shen YJ,Chen ZJ,Zhao YR

    更新日期:2012-02-01 00:00:00

  • Activated T lymphocytes, rheumatoid factor and erythrocyte sedimentation rate assays in rheumatoid arthritis.

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Bartfeld H,Dham C

    更新日期:1988-01-01 00:00:00

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    journal_title:Rheumatology international

    pub_type: 杂志文章,评审


    authors: Lin Q,Zhang M,Tang H,Shen Y,Zhu Y,Xu Q,Li X

    更新日期:2020-05-01 00:00:00

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Peris P

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Senel K,Baygutalp F,Baykal T,Erdal A,Ugur M

    更新日期:2013-06-01 00:00:00

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Müller R,Kallikorm R,Põlluste K,Lember M

    更新日期:2012-10-01 00:00:00

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Xie X,Wu D,Chen H

    更新日期:2016-12-01 00:00:00

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Skinner-Taylor CM,Perez-Barbosa L,Barriga-Maldonado ES,Cardenas-de la Garza JA,Diaz-Angulo JE,Figueroa-Parra G,Riega-Torres J,Galarza-Delgado DA

    更新日期:2021-02-01 00:00:00

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    abstract::Anaemia of chronic disease (ACD) is a common extra-articular manifestation of rheumatoid arthritis (RA). Tumour necrosis factor alpha (TNF alpha) plays an important role in the development of ACD. The objective of the present study was to assess inhibition of in vitro colony-forming unit erythrocyte (CFUe) and blast-f...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Jongen-Lavrencic M,Peeters HR,Backx B,Touw IP,Vreugdenhil G,Swaak AJ

    更新日期:1994-01-01 00:00:00

  • Pro-brain natriuretic peptide (ProBNP) levels in North Indian children with Kawasaki disease.

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Reddy M,Singh S,Rawat A,Sharma A,Suri D,Rohit MK

    更新日期:2016-04-01 00:00:00

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    abstract::The expressions of some terminal glycotopes of synovial immunoglobulins G, A, and M were analysed in relation to rheumatoid arthritis (RA) progression defined according to early and advanced radiological changes in patients' hands. The relative amounts of terminal monosaccharides were determined by lectin-immunoblotti...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Kratz EM,Borysewicz K,Katnik-Prastowska I

    更新日期:2010-08-01 00:00:00

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Pavlov-Dolijanovic SR,Vujasinovic Stupar NZ,Gavrilov N,Seric S

    更新日期:2014-11-01 00:00:00

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Caldas CA,de Carvalho JF

    更新日期:2012-05-01 00:00:00

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Cairoli E,Pérez G,Briva A,Cancela M,Alonso J

    更新日期:2010-03-01 00:00:00

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    journal_title:Rheumatology international

    pub_type: 杂志文章,多中心研究


    authors: Ghozzi M,Sakly W,Mankaï A,Bouajina E,Bahri F,Nouira R,Kechrid C,Ghedira I

    更新日期:2014-05-01 00:00:00

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Zhang ZL,Wang Y,Zhou W,Hao YJ

    更新日期:2009-04-01 00:00:00

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Oelzner P,Schwabe A,Lehmann G,Eidner T,Franke S,Wolf G,Hein G

    更新日期:2008-09-01 00:00:00

  • Frequency and role of low molecular weight IgM in systemic lupus erythematosus. Study of patients from different ethnic origins.

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Roberts-Thomson PJ,Shepherd K,Bradley J,Boey ML

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  • Human papillomavirus and chlamydia trachomatis infections in rheumatoid arthritis under anti-TNF therapy: an observational study.

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Waisberg MG,Ribeiro AC,Candido WM,Medeiros PB,Matsuzaki CN,Beldi MC,Tacla M,Caiaffa-Filho HH,Bonfa E,Silva CA

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  • Defining functioning categories in axial Spondyloarthritis: the role of the ASAS Health Index.

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Di Carlo M,Lato V,Di Matteo A,Carotti M,Salaffi F

    更新日期:2017-05-01 00:00:00

  • Pattern-based diagnosis and screening of differentially expressed serum proteins for rheumatoid arthritis by proteomic fingerprinting.

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Long L,Li R,Li Y,Hu C,Li Z

    更新日期:2011-08-01 00:00:00

  • Autophagy is a key feature in the pathogenesis of systemic sclerosis.

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Frech T,De Domenico I,Murtaugh MA,Revelo MP,Li DY,Sawitzke AD,Drakos S

    更新日期:2014-03-01 00:00:00

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Piga M,Casula L,Sanna S,Perra D,Floris A,Antonelli A,Cauli A,Mathieu A

    更新日期:2016-01-01 00:00:00

  • Free radicals and antioxidants in primary fibromyalgia: an oxidative stress disorder?

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Bagis S,Tamer L,Sahin G,Bilgin R,Guler H,Ercan B,Erdogan C

    更新日期:2005-04-01 00:00:00

  • Cyclooxygenase-2 polymorphisms and risk of systemic lupus erythematosus in Koreans.

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Her MY,El-Sohemy A,Cornelis MC,Kim TH,Bae SC

    更新日期:2006-11-01 00:00:00

  • Alpha 1-antitrypsin activity is markedly decreased in Wegener's granulomatosis.

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Mota A,Sahebghadam Lotfi A,Jamshidi AR,Najavand S

    更新日期:2014-04-01 00:00:00

  • Efficacy and safety of extending intravenous tocilizumab intervals from 4 to 6 weeks in rheumatoid arthritis patients with good response to 4-week intervals.

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Saiki O,Uda H

    更新日期:2018-12-01 00:00:00

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    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Santini P,Politi L,Vedova PD,Scandurra R,Scotto d'Abusco A

    更新日期:2014-05-01 00:00:00