TGF-β signal transduction pathways and osteoarthritis.

abstract：:Gender may produce different characteristics in the manifestation of systemic lupus erythematosus (SLE). The present study investigated the influence of gender on clinical, laboratory, autoantibodies and histopathological classes of lupus nephritis (LN). As much as 81 patients diagnosed with SLE (ACR criteria) and act...

journal_title：Rheumatology international

authors： de Carvalho JF,do Nascimento AP,Testagrossa LA,Barros RT,Bonfá E

更新日期：2010-08-01 00:00:00

abstract：:The objective was to investigate the effect of activin A on matrix metalloproteinase 3 (MMP-3) production and to identify the role of activin A in chondroprotection. SW1353 cells, a human chondrosarcoma cell line, were stimulated with interleukin (IL) 1alpha and tumor necrosis factor (TNF) alpha, and the concentration...

journal_title：Rheumatology international

authors： Chang DM,Liu SH,Lee HS,Lai JH,Chen CH

更新日期：2007-09-01 00:00:00

abstract：:The synovial fluids (SF) of patients with rheumatoid arthritis (RA) were investigated for their effects on thymocytes of C3H/HeJ mice. Of the 20 SF tested, 17 (85%) showed an augmentation of the phytohaemagglutinin (PHA) induced thymocyte stimulation. Out of 16 SF of patients with osteoarthrosis, such an activity was ...

journal_title：Rheumatology international

authors： Fontana A,Hengartner H,Weber E,Fehr K,Grob PJ,Cohen G

更新日期：1982-01-01 00:00:00

abstract：:Solid organ transplantation is an important lifesaving procedure mainly performed in patients with end-stage organ failure such as liver cirrhosis, congestive heart failure, and end-stage renal disease. While these complications are among the most preventable adverse effects of solid organ transplantation, these are g...

journal_title：Rheumatology international

authors： Movassaghi S,Nasiri Toosi M,Bakhshandeh A,Niksolat F,Khazaeipour Z,Tajik A

更新日期：2012-08-01 00:00:00

abstract：:Juvenile idiopathic arthritis (JIA) is the most common diagnosis in children and adolescents with rheumatic disorders. In many children and adolescents, JIA is successfully treated with non-steroidal anti-inflammatory drugs (NSAID) and physiotherapy. However, in a significant number of cases the disease is resistant t...

journal_title：Rheumatology international

authors： Niehues T,Horneff G,Michels H,Höck MS,Schuchmann L,Working Groups Pediatric Rheumatology Germany (AGKJR).,Pediatric Rheumatology Austria.

更新日期：2005-04-01 00:00:00

abstract：:The objective of this study was to determine whether levels of soluble receptors for tumor necrosis factor type I and type II (sTNF-RI and sTNF-RII) as measured in paired synovial fluids (SF) of arthritis patients are associated with clinical or laboratory parameters of local inflammation. sTNF-RI and -RII were measur...

journal_title：Rheumatology international

authors： Miltenburg AM,Aderka D,van Laar JM,Wallach D,Breedveld FC

更新日期：1993-01-01 00:00:00

abstract：:Fibrosis is unregulated tissue repair that may cause impairment of organ function, especially in end-organ damage. Systemic sclerosis (SSc) is the prototype systemic fibrosing disorder. Classical targets for fibrosis in SSc like transforming growth factor Beta (TGF-β), Interleukin-6 (IL-6), and multiple tyrosine kinas...

journal_title：Rheumatology international

authors： Ahmed S,Misra DP,Agarwal V

更新日期：2019-07-01 00:00:00

abstract：:This study was designed to investigate the association of oral ulceration and oral health factors, together with psycho-social well-being in Behçet's disease (BD), and to clarify the importance of psycho-social support of patients in the overall management of BD. The study comprised of a cohort of 146 BD patients (mea...

journal_title：Rheumatology international

authors： Senusi A,Higgins S,Fortune F

更新日期：2018-10-01 00:00:00

abstract：:The purpose of this study was to determine the association of fibromyalgia (FM) with temporomandibular disorder (TMD) and masticatory myofascial pain (MMP). Thirty-one consecutive women diagnosed as having FM according to American College of Rheumatology criteria and 21 consecutive women diagnosed as having TMD were i...

journal_title：Rheumatology international

authors： Leblebici B,Pektaş ZO,Ortancil O,Hürcan EC,Bagis S,Akman MN

更新日期：2007-04-01 00:00:00

abstract：:The main objective of this study was to assess the symptoms and functional difficulties caused by rheumatoid arthritis through application of the willingness to pay (WTP) method. Structured questionnaire study was conducted among 242 RA patients. The subjects were asked to evaluate their functional capacity using visu...

journal_title：Rheumatology international

authors： Tuominen R,Azbel M,Hemmilä J,Möttönen T

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Axillary lymph nodes (ALNs) are often seen on chest computed tomography (CT) in rheumatoid arthritis (RA) patients. Early reports described lymphadenopathy as one of the systemic manifestations rather than regional lymphadenopathy secondary to drainage from the affected joints. Subsequently, the importance o...

journal_title：Rheumatology international

authors： Hasegawa M,Sakai F,Konda N,Okabayashi A,Katsura H,Seto Y

更新日期：2018-06-01 00:00:00

abstract：:Primary Sjögren syndrome (pS) is associated with autoantibodies such as rheumatoid factor (RF) and anti-nuclear antibodies such as anti-Ro (SS-A) and/or La (SS-B). Recent developments within autoimmune diagnostics allow quantitation of RF subclasses and anti-Ro epitopes. Will this refinement by autoimmune diagnostics ...

journal_title：Rheumatology international

authors： Meek B,Kelder JC,Claessen AME,van Houte AJ,Ter Borg EJ

更新日期：2018-08-01 00:00:00

abstract：:Our aim was to investigate the relationship between the DNA methylation status of glucocorticoid receptor (GR) gene promoter and mRNA expression level of GRα gene of peripheral blood mononuclear cells (PBMCs) in patients with systemic lupus erythematosus (SLE). Fifteen newly emerging SLE patients and fifteen healthy c...

journal_title：Rheumatology international

authors： Chen H,Fan J,Shou Q,Zhang L,Ma H,Fan Y

更新日期：2015-08-01 00:00:00

abstract：:Nailfold videocapillaroscopy was performed in 21 controls (C) and 21 patients (P) with systemic lupus erythematosus (SLE) classified according to the American College of Rheumatology, with, at least, 1 year of diagnosed disease and having low activity (MEX-SLEDAI) and sequel (SLICC) indexes at the time of the examinat...

journal_title：Rheumatology international

authors： Dancour MA,Vaz JL,Bottino DA,Bouskela E

更新日期：2006-05-01 00:00:00

abstract：:Acute pseudogout of the neck, also known as the crowned dens syndrome, is a rare cause of neck pain characterised by crystalline deposition in periodontoid articular tissues. It is typified clinically by severe cervical pain and stiffness, often in conjunction with pyrexia and raised inflammatory markers. As such, it ...

journal_title：Rheumatology international

authors： Siau K,Lee M,Laversuch CJ

更新日期：2011-01-01 00:00:00

abstract：:The aim of the study was to evaluate the frequency of extra-articular manifestations (EAMs) of rheumatoid arthritis (RA) in a series of patients from nine Italian rheumatology clinics. A total of 587 patients underwent direct questioning, complete physical evaluation, and review of medical records and laboratory data....

journal_title：Rheumatology international

authors： Cimmino MA,Salvarani C,Macchioni P,Montecucco C,Fossaluzza V,Mascia MT,Punzi L,Davoli C,Filippini D,Numo R

更新日期：2000-01-01 00:00:00

abstract：:Splenectomy may be necessary to treat systemic lupus erythematosus (SLE) patients with thrombocytopenia; however, whether performing a splenectomy on patients without SLE increases the subsequent risk of SLE remains unknown. Therefore, this study was conducted to determine the association between splenectomy and SLE. ...

journal_title：Rheumatology international

authors： Hsu CY,Chen HJ,Hsu CY,Kao CH

更新日期：2016-02-01 00:00:00

abstract：:Antibodies to citrullinated proteins have been described in patients with rheumatoid arthritis (RA) and these appear to be the most specific markers of the disease. Our objective was to determine the frequency of antibodies to cyclic citrullinated peptides (CCPs) in patients with RA and the association of anti-CCP ant...

journal_title：Rheumatology international

authors： Serdaroğlu M,Cakirbay H,Değer O,Cengiz S,Kul S

更新日期：2008-08-01 00:00:00

abstract：:A period of 4 weeks (w) has been recommended for rheumatoid arthritis (RA) patients as the interval between intravenous (IV) tocilizumab (TCZ, 8 mg/kg). In a previous paper, we showed the possibility that the interval between successive IV TCZ can be extended from 4 to 6 weeks in more than 60% of patients with low dis...

journal_title：Rheumatology international

authors： Saiki O,Uda H

更新日期：2018-12-01 00:00:00

abstract：:Biological markers of inflammation are useful for the diagnosis and monitoring of inflammatory rheumatic diseases. The present study tested, whether serum amyloid A (SAA) could be used as a marker of inflammatory disease activity in ankylosing spondylitis (AS). In 72 patients with AS, the two valuable surrogate marker...

journal_title：Rheumatology international

authors： Lange U,Boss B,Teichmann J,Klör HU,Neeck G

更新日期：2000-01-01 00:00:00

abstract：:Rheumatoid vasculitis (RV) is an uncommon but potentially catastrophic complication of rheumatoid arthritis (RA). There are few current extensive studies and no consensus regarding the clinical, laboratory, histologic features and management or prognosis of RV. We report a case of RV in a 74-year old woman with a long...

journal_title：Rheumatology international

authors： Benucci M,Li Gobbi F,Saviola G,Manfredi M

更新日期：2008-10-01 00:00:00

abstract：:The American Rheumatism Association (ARA) clinical criteria have been tested in systemic lupus erythematosus (SLE), progressive systemic sclerosis, polyarteritis nodosa and polymyositis/dermatomyositis. Hospital admissions from a defined population over the same period were studied. Increased weighting of the scores f...

journal_title：Rheumatology international

authors： Tan PL,Borman GB,Wigley RD

更新日期：1981-01-01 00:00:00

abstract：:The study objective was to examine natural variation of the patient-reported outcome measures fatigue, pain, patient global assessment (PaGl) and the Bath Ankylosing Spondylitis Functional Index (BASFI) in patients with stable axial spondyloarthropathy (ax-SpA) defined on the basis of the Bath Spondylitis Ankylosing D...

journal_title：Rheumatology international

authors： Madsen OR

更新日期：2018-03-01 00:00:00

abstract：:To describe the profile of Enthesitis Related Arthritis' (ERA) patients, in the era of biologic DMARDs (bDMARDs). This retrospective cohort study included patients with ERA monitored on a 3-month schedule for at least 1 year. Their metric assessment included the disease status and damage by applying the contemporary t...

journal_title：Rheumatology international

authors： Deligeorgakis D,Trachana M,Pratsidou-Gertsi P,Dimopoulou D,Haidich AB,Garyfallos A

更新日期：2020-06-01 00:00:00

abstract：:Methotrexate (MTX) can be toxic to patients suffering from end stage renal disease (ESRD) on hemodialysis even at low doses. This increase in toxicity is more notable in terms of bone marrow suppression in the form of pancytopenia. Many methods of elimination including dialysis itself have been proven ineffective, and...

journal_title：Rheumatology international

authors： Al-Hasani H,Roussou E

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:Neprilysin (neutral endopeptidase, 3:4:24:11, CD10) (NEP) is a Zn metallopeptidase linked to controlling inflammation through the degradation of neuropeptides involved in neurogenic inflammation of chronic rheumatic diseases. The aim of our study was to evaluate circulating activity and cellular expression of...

journal_title：Rheumatology international

authors： Simonini G,Azzari C,Gelli AM,Giani T,Calabri GB,Leoncini G,Del Rosso A,Generini S,Cimaz R,Cerinic MM,Falcini F

更新日期：2005-06-01 00:00:00

abstract：:To develop a semi-automated method to quantify inflammation in sacroiliac (SI) joints by measuring bone marrow edema (BME) on MRI. The SCAISS was designed as an image-processing software. Validation followed: (1) three readers evaluated SI images of 23 patients with axial SpA and various levels of BME severity with th...

journal_title：Rheumatology international

authors： Zarco P,Almodóvar R,Bueno Á,Molinero LM,SCAISS Study Group.

更新日期：2018-10-01 00:00:00

abstract：:Catalase (CAT) and peroxisome proliferator activated receptor-gamma2 (PPARgamma2) are important regulators of oxidative stress and inflammation, and may contribute to the development of rheumatoid arthritis (RA). We investigated the association between CAT and PPARgamma2 genotypes and risk and severity of RA using 474...

journal_title：Rheumatology international

authors： El-Sohemy A,Cornelis MC,Park YW,Bae SC

更新日期：2006-03-01 00:00:00

abstract：:The aim of the study was to estimate the annual direct costs of biological therapies in rheumatoid arthritis (RA), and to establish possible factors associated with those costs. The main data source was the Moroccan registry of biological therapies in rheumatic diseases (RBSMR Registry). We included patients with avai...

journal_title：Rheumatology international

authors： Fellous S,Rkain H,Ahid S,Abouqal R,Tahiri L,Hmamouchi I,Achemlal L,El Bouchti I,El Maghraoui A,Ghozlani I,Hassikou H,Harzy T,Ichchou L,Mkinsi O,Niamane R,Bahiri R,Allali F

更新日期：2021-01-02 00:00:00

abstract：:The neutrophilic granule protein proteinase 3 (PR3) is the preferred target antigen of anti-neutrophil cytoplasmic antibodies (ANCA) found in the serum of patients with Wegener's granulomatosis, a systemic small-vessel vasculitis. Due to the lack of data concerning the murine homologue of human PR3, we assessed the ne...

journal_title：Rheumatology international

authors： Relle M,Thomaidis T,Galle PR,Schwarting A

更新日期：2011-08-01 00:00:00