Improved rheumatoid digital vasculitis in a patient treated with TNFalpha agent blocking (infliximab).

Abstract:

:Rheumatoid vasculitis (RV) is an uncommon but potentially catastrophic complication of rheumatoid arthritis (RA). There are few current extensive studies and no consensus regarding the clinical, laboratory, histologic features and management or prognosis of RV. We report a case of RV in a 74-year old woman with a long (14 years) history of RA, who developed vasculitis of distal arteries with gangrene of digits of upper and lower extremities. After the failure of various immunosuppressive drugs (cyclophosphamide, methotrexate), the patient was treated with anti-TNFalpha infliximab. Digital gangrene healed within four months from the start of anti-TNFalpha treatment.

journal_name

Rheumatol Int

authors

Benucci M,Li Gobbi F,Saviola G,Manfredi M

doi

10.1007/s00296-008-0592-x

subject

Has Abstract

pub_date

2008-10-01 00:00:00

pages

1253-5

issue

12

eissn

0172-8172

issn

1437-160X

journal_volume

28

pub_type

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