Abstract:
:A 7-year-old child was first admitted for persistent fever of 15-day duration and suspected meningitis. Kawasaki syndrome was lately diagnosed upon the recognition of an extensive diffuse coronary artery damage characterized by medium-sized aneurysms of the epicardial vessels. An eccentric thrombus along the inferior wall of the left anterior descending artery suspected at transthoracic echocardiography was confirmed by coronary computed tomography angiography scan, without significant segmental stenosis. Strict cardiac surveillance and anticoagulant therapy were maintained, and no ischemic complications occurred at a short-term follow-up. This report emphasizes that thrombosis can be observed even in medium-sized aneurysms when the diagnosis of Kawasaki syndrome is delayed.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
De Rosa G,Cefalo MG,Marano R,Piastra M,Delogu AB,Rigante Ddoi
10.1007/s00296-011-1814-1subject
Has Abstractpub_date
2012-03-01 00:00:00pages
809-14issue
3eissn
0172-8172issn
1437-160Xjournal_volume
32pub_type
杂志文章,评审abstract::Macrophage activation syndrome (MAS) is a hyper-inflammatory disorder secondary to a rheumatic disease such as systemic juvenile idiopathic arthritis (SJIA) and systemic lupus erythematosus (SLE). We aimed to present the characteristics of our pediatric MAS patients. Clinical features, laboratory parameters, treatment...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-016-3545-9
更新日期:2016-10-01 00:00:00
abstract::Neopterin levels of serum and fluid were determined in 30 patients with inflammatory synovial fluids and in 30 controls with joint effusions induced by trauma or osteoarthritis. Neopterin was significantly elevated in inflammatory fluids. There was no correlation with the acute phase reactants. Neopterin levels were s...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00541281
更新日期:1986-01-01 00:00:00
abstract::In a prospective study 222 sera from 56 patients with systemic lupus erythematosus (SLE) were tested for antibodies to poly(A), poly dAT and histones using enzyme-linked immunosorbent assay (ELISA). Patients with active disease had significantly more often antibodies to poly(A), poly dAT and histones than patients wit...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00541200
更新日期:1984-01-01 00:00:00
abstract::Behçet's disease (BD) commonly presents with articular manifestations and thrombotic vasculopathy. Arthritis of BD characteristically demonstrates a recurrent and nondestructive course. The pathobiological basis of the thrombotic vasculopathy and protective factors against cartilage destruction in arthritis of BD have...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-003-0324-1
更新日期:2004-03-01 00:00:00
abstract::The objective of the study was to determine the clinical features and treatment course in Canadian patients with dermatomyositis (DM) associated with the anti-melanoma differentiation-associated gene 5 antibody (MDA5). A retrospective chart review of consecutive patients with anti-MDA5 antibody DM from two Canadian te...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-019-04398-2
更新日期:2019-11-01 00:00:00
abstract::Analyses of the synovial tissue and fluid T lymphocytes obtained from patients with rheumatoid arthritis revealed multiple functional defects in the regulation of autologous blood B cell differentiation into cells secreting immunoglobulin. These abnormalities were not found in peripheral blood T lymphocytes from the s...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00541164
更新日期:1982-01-01 00:00:00
abstract::In the present study, we have investigated comparatively the inflammatory response of patients with active and inactive osteoarthritis. The sera from 31 healthy individuals, 37 patients with active OA, and 19 patients with inactive OA were assayed for TNF-alpha, IL-6, sRANKL, RANTES, and MRP8 using ELISA in order to e...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-0864-0
更新日期:2009-08-01 00:00:00
abstract::Ultrasonography (US) and power Doppler sonography (PDS) was used to investigate causes of new onset of shoulder pain and sites of shoulder inflammation in 157 shoulders of 99 patients with rheumatoid arthritis (RA). US detected effusion and/or synovitis in 92/157 glenohumeral joints, subdeltoid bursitis in 56/157 shou...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-007-0465-8
更新日期:2008-03-01 00:00:00
abstract::The Australian/Canadian Osteoarthritis Hand Index (AUSCAN) is a patient self-reported 15-item questionnaire measuring the severity of hand osteoarthritis symptoms in the respect of pain, stiffness, and function. In this study, we developed a Korean version of the AUSCAN Index (K-AUSCAN) and confirmed its reliability, ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-011-2227-x
更新日期:2012-11-01 00:00:00
abstract::Fatigue has a large impact on quality of life and is still unmanageable for many patients. Study aims were describe (1) the prevalence and pattern of fatigue over time in patients with early rheumatoid arthritis under a treat-to-target strategy and (2) identify predictive factors for worsening and recovering of fatigu...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-018-4102-5
更新日期:2018-09-01 00:00:00
abstract::Uveitis may represent an opportunity to diagnose spondyloarthropathies (SpA) earlier and influence treatment decisions. We describe the percentage of acute anterior uveitis (AAU) in a diverse group of SpA patients seen at one academic setting and compare demographic and clinical characteristics according to the presen...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-019-04386-6
更新日期:2019-09-01 00:00:00
abstract::Necrotic areas of rheumatoid nodules were investigated electron microscopically. PMNs in different stages of disintegration were present in all cases. Granular material, sometimes in a fiberlike orientation, and small fibrils without periodicity were detected between the collagenous fibers. It is assumed that granular...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00541219
更新日期:1981-01-01 00:00:00
abstract::Osteoarthritis (OA) is the most common form of arthritis, resulting in substantial disability and economic burden worldwide. While its exact pathogenesis remains elusive, both in vitro and human population-based studies have merged to support the hypothesis that TGF-β/BMP-mediated signalling pathways play a role in th...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-015-3251-z
更新日期:2015-08-01 00:00:00
abstract::Osteomyelitis variolosa is an osteoarticular complication of small pox infection. We are presenting a case of osteomyelitis variolosa, who presented to us with fracture of ankle on the involved side with other orthopedic sequelae of small pox infection, which he contracted during his childhood period. We have discusse...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-011-2194-2
更新日期:2012-11-01 00:00:00
abstract::Sphingolipids are components of the plasma membrane whose metabolic manipulation is of interest as a potential therapeutic approach in a number of diseases. Sphingosine kinase 1 (SphK1), the major kinase that phosphorylates sphingosine to sphingosine-1-phosphate (S1P), was previously shown by our group and others to m...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-012-2493-2
更新日期:2013-10-01 00:00:00
abstract::Interleukin-6 (IL-6) was detected at low levels in plasma [0.014 +/- 0.006 ng/ml (mean +/- SEM] and in high amounts in synovial fluid [SF; 2.6 +/- 2.2 ng/ml (mean +/- SEM)] of patients with rheumatoid arthritis. No correlation of IL-6 levels in plasma or SF with the ESR (n = 15) or with histological parameters of acut...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00307733
更新日期:1993-01-01 00:00:00
abstract::One hundred and eighteen unrelated Greek patients with classic rheumatoid arthritis (RA) were tissue-typed for HLA-A, -B, -DR antigens and the frequency was compared to that of healthy controls. Greek RA patients regardless of sex, anatomical severity, seropositivity and age at disease onset are not associated with an...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00541336
更新日期:1985-01-01 00:00:00
abstract::Systemic sclerosis is a connective tissue disease in which oxidative stress represents an important player among the complex pathogenetic mechanisms of the disease. Iloprost, an analogue of natural prostacyclin, is used in systemic sclerosis for the treatment of severe Raynaud's phenomenon and ischemic ulcers. There i...
journal_title:Rheumatology international
pub_type: 临床试验,杂志文章
doi:10.1007/s00296-007-0443-1
更新日期:2008-02-01 00:00:00
abstract::Serotonin antagonists show impressive analgesic efficacy in rheumatoid arthritis, osteoarthritis (OA) or fibromyalgia; however, this effect is not well understood. We examined the mechanism of serotonin-induced inflammation and its antagonists in OA. Serotonin receptor subtypes and COX-2 were analysed by RT-PCR from s...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0564-1
更新日期:2008-08-01 00:00:00
abstract::Caffeine, a commonly consumed food constituent, is known to exert beneficial physiological effects in humans. There is a lack of comprehensive population data for the effects of caffeine intake on urate metabolism. Therefore, the aim of this study was to determine whether coffee, tea, and caffeine intake influences se...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-014-3061-8
更新日期:2015-02-01 00:00:00
abstract::The objective was to investigate the effect of activin A on matrix metalloproteinase 3 (MMP-3) production and to identify the role of activin A in chondroprotection. SW1353 cells, a human chondrosarcoma cell line, were stimulated with interleukin (IL) 1alpha and tumor necrosis factor (TNF) alpha, and the concentration...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-007-0350-5
更新日期:2007-09-01 00:00:00
abstract::Monocyte interleukin-1 (IL-1) production in vitro was studied in 49 patients with rheumatoid arthritis (RA) and 31 controls. Twenty-six of the RA patients were studied prospectively for up to 12 months after beginning chrysotherapy. About half of the patients (group 1) exhibited pretreatment levels of monocyte IL-1 se...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF02274840
更新日期:1990-01-01 00:00:00
abstract::Chronic inflammation starting early in life and continuing into adulthood may predispose children with Juvenile Idiopathic Arthritis (JIA) to cardiovascular (CV) complications. To compare non-invasive CV risk markers- left ventricular mass index (LVMi), brachial artery flow mediated dilatation (FMD) and carotid artery...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-020-04689-z
更新日期:2021-02-01 00:00:00
abstract::Rheumatoid arthritis (RA) is a systemic autoimmune disease that causes joint pain, inflammation, and loss of function. Disease pathogenesis involves activation and proliferation of autoreactive pro-inflammatory effector T cells. While the details of RA onset and progression remain controversial, dendritic cell (DC) nu...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-017-3671-z
更新日期:2017-07-01 00:00:00
abstract::Fibromyalgia syndrome is characterized by chronic generalized pain accompanied by a broad symptomatologic spectrum. Besides chronic fatigue, sleep disturbances, headaches and cognitive dysfunction that are extensively described in the literature, a considerable proportion of patients with fibromyalgia experience gastr...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-014-3109-9
更新日期:2015-03-01 00:00:00
abstract::A critical analysis has been performed of reports published on the incidence of gastro-intestinal (GI) side-effects found in arthritic patients being treated with non-steroid anti-inflammatory (NSAI) drugs. The results show the following: 1. The incidence of GI ulceration (as revealed by gastroscopy) and haemorrhage i...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00541263
更新日期:1982-01-01 00:00:00
abstract::We present the case of a patient with long-standing rheumatoid arthritis and an acute onset of total dysfunction of the posterior tibial tendon. On MRI, a rupture of the tendon was apparent. Intraoperatively, however, massive tenosynovitis with stricture of the tendon was identified as the cause of posterior tibial te...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-002-0183-1
更新日期:2002-05-01 00:00:00
abstract:UNLABELLED:The objective of this study is to provide a critical overview of available instruments to assess impairments in patients with rheumatic disorders, and to recommend reliable and valid instruments for use in allied health care and rehabilitation medicine. A computer-aided literature search (1982-2004) in sever...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-005-0603-0
更新日期:2005-09-01 00:00:00
abstract::Arthrocutaneous disorders including Reiter's syndrome, psoriasiform rashes, and other forms of chronic arthritis and enthesopathy, such as psoriatic arthritis, occur with an increased prevalence in the setting of HIV infection. Herein we describe the spectrum and prevalence of musculoskeletal and allied skin disorders...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/BF00271870
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate the relationships among bone mineral densities (BMD) in the calcaneus and leg activity of daily living (L-ADL) in rheumatoid arthritis (RA) patients. METHODS:We measured and compared calcaneus BMD using single X-ray absorptiometry and lumbar spine and femoral neck BM...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-003-0421-1
更新日期:2005-04-01 00:00:00