Delayed diagnosis of Kawasaki syndrome and thrombosis of a medium-sized aneurysm of the anterior descending coronary artery: case report and literature review.


:A 7-year-old child was first admitted for persistent fever of 15-day duration and suspected meningitis. Kawasaki syndrome was lately diagnosed upon the recognition of an extensive diffuse coronary artery damage characterized by medium-sized aneurysms of the epicardial vessels. An eccentric thrombus along the inferior wall of the left anterior descending artery suspected at transthoracic echocardiography was confirmed by coronary computed tomography angiography scan, without significant segmental stenosis. Strict cardiac surveillance and anticoagulant therapy were maintained, and no ischemic complications occurred at a short-term follow-up. This report emphasizes that thrombosis can be observed even in medium-sized aneurysms when the diagnosis of Kawasaki syndrome is delayed.


Rheumatol Int


De Rosa G,Cefalo MG,Marano R,Piastra M,Delogu AB,Rigante D




Has Abstract


2012-03-01 00:00:00












  • Macrophage activation syndrome in children with systemic juvenile idiopathic arthritis and systemic lupus erythematosus.

    abstract::Macrophage activation syndrome (MAS) is a hyper-inflammatory disorder secondary to a rheumatic disease such as systemic juvenile idiopathic arthritis (SJIA) and systemic lupus erythematosus (SLE). We aimed to present the characteristics of our pediatric MAS patients. Clinical features, laboratory parameters, treatment...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Aytaç S,Batu ED,Ünal Ş,Bilginer Y,Çetin M,Tuncer M,Gümrük F,Özen S

    更新日期:2016-10-01 00:00:00

  • Neopterin production in inflamed knee joints: high levels in synovial fluids.

    abstract::Neopterin levels of serum and fluid were determined in 30 patients with inflammatory synovial fluids and in 30 controls with joint effusions induced by trauma or osteoarthritis. Neopterin was significantly elevated in inflammatory fluids. There was no correlation with the acute phase reactants. Neopterin levels were s...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Maerker-Alzer G,Diemer O,Strümper R,Rohe M

    更新日期:1986-01-01 00:00:00

  • Enzyme-linked immunosorbent assays for antibodies to poly(A), poly dAT and histones: possibly useful tools for the evaluation of prognosis and disease activity in systemic lupus erythematosus.

    abstract::In a prospective study 222 sera from 56 patients with systemic lupus erythematosus (SLE) were tested for antibodies to poly(A), poly dAT and histones using enzyme-linked immunosorbent assay (ELISA). Patients with active disease had significantly more often antibodies to poly(A), poly dAT and histones than patients wit...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Helve T,Gripenberg M,Kurki P,Teppo AM,Wegelius O

    更新日期:1984-01-01 00:00:00

  • Plasminogen activator inhibitor-1 as a link between pathological fibrinolysis and arthritis of Behçet's disease.

    abstract::Behçet's disease (BD) commonly presents with articular manifestations and thrombotic vasculopathy. Arthritis of BD characteristically demonstrates a recurrent and nondestructive course. The pathobiological basis of the thrombotic vasculopathy and protective factors against cartilage destruction in arthritis of BD have...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Oztürk MA,Ertenli I,Kiraz S,C Haznedaroğlu I,Celik I,Kirazli S,Calgüneri M

    更新日期:2004-03-01 00:00:00

  • Clinical spectrum and therapeutics in Canadian patients with anti-melanoma differentiation-associated gene 5 (MDA5)-positive dermatomyositis: a case-based review.

    abstract::The objective of the study was to determine the clinical features and treatment course in Canadian patients with dermatomyositis (DM) associated with the anti-melanoma differentiation-associated gene 5 antibody (MDA5). A retrospective chart review of consecutive patients with anti-MDA5 antibody DM from two Canadian te...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审


    authors: Huang K,Vinik O,Shojania K,Yeung J,Shupak R,Nimmo M,Avina-Zubieta JA

    更新日期:2019-11-01 00:00:00

  • Multiple abnormalities in immunoregulatory function of synovial compartment T cells in patients with rheumatoid arthritis. Recognition of a helper augmentation effect.

    abstract::Analyses of the synovial tissue and fluid T lymphocytes obtained from patients with rheumatoid arthritis revealed multiple functional defects in the regulation of autologous blood B cell differentiation into cells secreting immunoglobulin. These abnormalities were not found in peripheral blood T lymphocytes from the s...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Romain PL,Burmester GR,Enlow RW,Winchester RJ

    更新日期:1982-01-01 00:00:00

  • Inflammatory response in patients with active and inactive osteoarthritis.

    abstract::In the present study, we have investigated comparatively the inflammatory response of patients with active and inactive osteoarthritis. The sera from 31 healthy individuals, 37 patients with active OA, and 19 patients with inactive OA were assayed for TNF-alpha, IL-6, sRANKL, RANTES, and MRP8 using ELISA in order to e...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Toncheva A,Remichkova M,Ikonomova K,Dimitrova P,Ivanovska N

    更新日期:2009-08-01 00:00:00

  • Sites of inflammation in painful rheumatoid shoulder assessed by musculoskeletal ultrasound and power Doppler sonography.

    abstract::Ultrasonography (US) and power Doppler sonography (PDS) was used to investigate causes of new onset of shoulder pain and sites of shoulder inflammation in 157 shoulders of 99 patients with rheumatoid arthritis (RA). US detected effusion and/or synovitis in 92/157 glenohumeral joints, subdeltoid bursitis in 56/157 shou...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Stegbauer J,Rump LC,Weiner SM

    更新日期:2008-03-01 00:00:00

  • Cross-cultural adaptation, validation, and responsiveness of the Korean version of the AUSCAN Osteoarthritis Index.

    abstract::The Australian/Canadian Osteoarthritis Hand Index (AUSCAN) is a patient self-reported 15-item questionnaire measuring the severity of hand osteoarthritis symptoms in the respect of pain, stiffness, and function. In this study, we developed a Korean version of the AUSCAN Index (K-AUSCAN) and confirmed its reliability, ...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Moon KW,Lee SS,Kim JH,Song R,Lee EY,Song YW,Bellamy N,Lee EB

    更新日期:2012-11-01 00:00:00

  • Fatigue in early, intensively treated and tight-controlled rheumatoid arthritis patients is frequent and persistent: a prospective study.

    abstract::Fatigue has a large impact on quality of life and is still unmanageable for many patients. Study aims were describe (1) the prevalence and pattern of fatigue over time in patients with early rheumatoid arthritis under a treat-to-target strategy and (2) identify predictive factors for worsening and recovering of fatigu...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Walter MJM,Kuijper TM,Hazes JMW,Weel AE,Luime JJ

    更新日期:2018-09-01 00:00:00

  • Anterior uveitis in patients with spondyloarthropathies in a single US academic center: a retrospective study.

    abstract::Uveitis may represent an opportunity to diagnose spondyloarthropathies (SpA) earlier and influence treatment decisions. We describe the percentage of acute anterior uveitis (AAU) in a diverse group of SpA patients seen at one academic setting and compare demographic and clinical characteristics according to the presen...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Gevorgyan O,Riad M,Sarran RD,Merrill PT,Block JA,Castrejon I

    更新日期:2019-09-01 00:00:00

  • Polymorphonuclear granulocytes in rheumatic tissue destruction. II. Demonstration of PMNs in rheumatoid nodules by electron microscopy.

    abstract::Necrotic areas of rheumatoid nodules were investigated electron microscopically. PMNs in different stages of disintegration were present in all cases. Granular material, sometimes in a fiberlike orientation, and small fibrils without periodicity were detected between the collagenous fibers. It is assumed that granular...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Mohr W,Köhler G,Wessinghage D

    更新日期:1981-01-01 00:00:00

  • TGF-β signal transduction pathways and osteoarthritis.

    abstract::Osteoarthritis (OA) is the most common form of arthritis, resulting in substantial disability and economic burden worldwide. While its exact pathogenesis remains elusive, both in vitro and human population-based studies have merged to support the hypothesis that TGF-β/BMP-mediated signalling pathways play a role in th...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审


    authors: Zhai G,Doré J,Rahman P

    更新日期:2015-08-01 00:00:00

  • Sequelae of osteomyelitis variolosa: a case report.

    abstract::Osteomyelitis variolosa is an osteoarticular complication of small pox infection. We are presenting a case of osteomyelitis variolosa, who presented to us with fracture of ankle on the involved side with other orthopedic sequelae of small pox infection, which he contracted during his childhood period. We have discusse...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Nema S,Vyas GS,Kukreja S

    更新日期:2012-11-01 00:00:00

  • Impact of sphingosine kinase 2 deficiency on the development of TNF-alpha-induced inflammatory arthritis.

    abstract::Sphingolipids are components of the plasma membrane whose metabolic manipulation is of interest as a potential therapeutic approach in a number of diseases. Sphingosine kinase 1 (SphK1), the major kinase that phosphorylates sphingosine to sphingosine-1-phosphate (S1P), was previously shown by our group and others to m...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Baker DA,Eudaly J,Smith CD,Obeid LM,Gilkeson GS

    更新日期:2013-10-01 00:00:00

  • Interleukin-6 in synovial fluid is closely associated with chronic synovitis in rheumatoid arthritis.

    abstract::Interleukin-6 (IL-6) was detected at low levels in plasma [0.014 +/- 0.006 ng/ml (mean +/- SEM] and in high amounts in synovial fluid [SF; 2.6 +/- 2.2 ng/ml (mean +/- SEM)] of patients with rheumatoid arthritis. No correlation of IL-6 levels in plasma or SF with the ESR (n = 15) or with histological parameters of acut...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Sack U,Kinne RW,Marx T,Heppt P,Bender S,Emmrich F

    更新日期:1993-01-01 00:00:00

  • Lack of HLA-antigen association in Greek rheumatoid arthritis patients.

    abstract::One hundred and eighteen unrelated Greek patients with classic rheumatoid arthritis (RA) were tissue-typed for HLA-A, -B, -DR antigens and the frequency was compared to that of healthy controls. Greek RA patients regardless of sex, anatomical severity, seropositivity and age at disease onset are not associated with an...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Papasteriades CA,Kappou ID,Skopouli FN,Barla MN,Fostiropoulos GA,Moutsopoulos HM

    更新日期:1985-01-01 00:00:00

  • Iloprost infusion does not reduce oxidative stress in systemic sclerosis.

    abstract::Systemic sclerosis is a connective tissue disease in which oxidative stress represents an important player among the complex pathogenetic mechanisms of the disease. Iloprost, an analogue of natural prostacyclin, is used in systemic sclerosis for the treatment of severe Raynaud's phenomenon and ischemic ulcers. There i...

    journal_title:Rheumatology international

    pub_type: 临床试验,杂志文章


    authors: Volpe A,Biasi D,Caramaschi P,Bambara LM,Carletto A,Degan M,Minuz P

    更新日期:2008-02-01 00:00:00

  • Serotonin mediates PGE2 overexpression through 5-HT2A and 5-HT3 receptor subtypes in serum-free tissue culture of macrophage-like synovial cells.

    abstract::Serotonin antagonists show impressive analgesic efficacy in rheumatoid arthritis, osteoarthritis (OA) or fibromyalgia; however, this effect is not well understood. We examined the mechanism of serotonin-induced inflammation and its antagonists in OA. Serotonin receptor subtypes and COX-2 were analysed by RT-PCR from s...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Seidel MF,Fiebich BL,Ulrich-Merzenich G,Candelario-Jalil E,Koch FW,Vetter H

    更新日期:2008-08-01 00:00:00

  • The effect of coffee, tea, and caffeine consumption on serum uric acid and the risk of hyperuricemia in Korean Multi-Rural Communities Cohort.

    abstract::Caffeine, a commonly consumed food constituent, is known to exert beneficial physiological effects in humans. There is a lack of comprehensive population data for the effects of caffeine intake on urate metabolism. Therefore, the aim of this study was to determine whether coffee, tea, and caffeine intake influences se...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Bae J,Park PS,Chun BY,Choi BY,Kim MK,Shin MH,Lee YH,Shin DH,Kim SK

    更新日期:2015-02-01 00:00:00

  • Activin A suppresses interleukin-1-induced matrix metalloproteinase 3 secretion in human chondrosarcoma cells.

    abstract::The objective was to investigate the effect of activin A on matrix metalloproteinase 3 (MMP-3) production and to identify the role of activin A in chondroprotection. SW1353 cells, a human chondrosarcoma cell line, were stimulated with interleukin (IL) 1alpha and tumor necrosis factor (TNF) alpha, and the concentration...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Chang DM,Liu SH,Lee HS,Lai JH,Chen CH

    更新日期:2007-09-01 00:00:00

  • The effect of gold treatment on monocyte interleukin-1 production in rheumatoid arthritis. A prospective study.

    abstract::Monocyte interleukin-1 (IL-1) production in vitro was studied in 49 patients with rheumatoid arthritis (RA) and 31 controls. Twenty-six of the RA patients were studied prospectively for up to 12 months after beginning chrysotherapy. About half of the patients (group 1) exhibited pretreatment levels of monocyte IL-1 se...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Danis VA,Kulesz AJ,Kelly DE,Nelson DS,Brooks PM

    更新日期:1990-01-01 00:00:00

  • Early-onset subclinical cardiovascular damage assessed by non-invasive methods in children with Juvenile Idiopathic Arthritis: analytical cross-sectional study.

    abstract::Chronic inflammation starting early in life and continuing into adulthood may predispose children with Juvenile Idiopathic Arthritis (JIA) to cardiovascular (CV) complications. To compare non-invasive CV risk markers- left ventricular mass index (LVMi), brachial artery flow mediated dilatation (FMD) and carotid artery...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Hussain KS,Gulati R,Satheesh S,Negi VS

    更新日期:2021-02-01 00:00:00

  • The function of myeloid dendritic cells in rheumatoid arthritis.

    abstract::Rheumatoid arthritis (RA) is a systemic autoimmune disease that causes joint pain, inflammation, and loss of function. Disease pathogenesis involves activation and proliferation of autoreactive pro-inflammatory effector T cells. While the details of RA onset and progression remain controversial, dendritic cell (DC) nu...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审


    authors: Yu MB,Langridge WHR

    更新日期:2017-07-01 00:00:00

  • An insight into the gastrointestinal component of fibromyalgia: clinical manifestations and potential underlying mechanisms.

    abstract::Fibromyalgia syndrome is characterized by chronic generalized pain accompanied by a broad symptomatologic spectrum. Besides chronic fatigue, sleep disturbances, headaches and cognitive dysfunction that are extensively described in the literature, a considerable proportion of patients with fibromyalgia experience gastr...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审


    authors: Slim M,Calandre EP,Rico-Villademoros F

    更新日期:2015-03-01 00:00:00

  • An analysis of the gastro-intestinal side-effects of non-steroidal anti-inflammatory drugs, with particular reference to comparative studies in man and laboratory species.

    abstract::A critical analysis has been performed of reports published on the incidence of gastro-intestinal (GI) side-effects found in arthritic patients being treated with non-steroid anti-inflammatory (NSAI) drugs. The results show the following: 1. The incidence of GI ulceration (as revealed by gastroscopy) and haemorrhage i...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Rainsford KD

    更新日期:1982-01-01 00:00:00

  • Posterior tibial tendon dysfunction and MR imaging in rheumatoid arthritis.

    abstract::We present the case of a patient with long-standing rheumatoid arthritis and an acute onset of total dysfunction of the posterior tibial tendon. On MRI, a rupture of the tendon was apparent. Intraoperatively, however, massive tenosynovitis with stricture of the tendon was identified as the cause of posterior tibial te...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Hasler P,Hintermann B,Meier M

    更新日期:2002-05-01 00:00:00

  • Impairment measures in rheumatic disorders for rehabilitation medicine and allied health care: a systematic review.

    abstract:UNLABELLED:The objective of this study is to provide a critical overview of available instruments to assess impairments in patients with rheumatic disorders, and to recommend reliable and valid instruments for use in allied health care and rehabilitation medicine. A computer-aided literature search (1982-2004) in sever...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审


    authors: Swinkels RA,Bouter LM,Oostendorp RA,van den Ende CH

    更新日期:2005-09-01 00:00:00

  • Aspects of the spectrum, prevalence and disease susceptibility determinants of Reiter's syndrome and related disorders associated with HIV infection.

    abstract::Arthrocutaneous disorders including Reiter's syndrome, psoriasiform rashes, and other forms of chronic arthritis and enthesopathy, such as psoriatic arthritis, occur with an increased prevalence in the setting of HIV infection. Herein we describe the spectrum and prevalence of musculoskeletal and allied skin disorders...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审


    authors: Brancato L,Itescu S,Skovron ML,Solomon G,Winchester R

    更新日期:1989-01-01 00:00:00

  • Calcaneus bone mineral density in Japanese women with rheumatoid arthritis.

    abstract:OBJECTIVES:The aim of this study was to investigate the relationships among bone mineral densities (BMD) in the calcaneus and leg activity of daily living (L-ADL) in rheumatoid arthritis (RA) patients. METHODS:We measured and compared calcaneus BMD using single X-ray absorptiometry and lumbar spine and femoral neck BM...

    journal_title:Rheumatology international

    pub_type: 杂志文章


    authors: Doi S,Kushida K,Miyamoto S,Sekioka Y,Suzuki M,Inoue T,Nagano A

    更新日期:2005-04-01 00:00:00