Correlation of serum levels of soluble intercellular adhesion molecule-1 with disease activity in systemic lupus erythematosus.

Abstract:

:Intercellular adhesion molecule-1 (ICAM-1) is a membrane-bound molecule primarily involved in cell-cell adhesive interactions of the immune system. It is a cytokine-induced glycoprotein involved in the recruitment of cells into tissues undergoing inflammatory responses. The levels of soluble ICAM-1 were measured in sera of patients with systemic lupus erythematosus (SLE) using sandwich enzyme-linked immunoassay. Serum levels (mean +/- SD) of soluble ICAM-1 (sICAM-1) were significantly higher in 24 patients with SLE than in 20 controls (372+/-42 ng/dL vs 231+/-29 ng/dL, P < 0.001). A statistically significant positive correlation was observed between sICAM-1 levels and SLE disease activity index (SLEDAI) score in SLE patients, and no correlation was found between sICAM-1 and CRP, SLEDAI and CRP, or SLEDAI and ESR in patient groups (P>0.05). These findings suggest that sICAM-1 measurement may serve as an additional serologic marker of disease activity in patients with SLE.

journal_name

Rheumatol Int

authors

Sari RA,Taysi S,Erdem F,Yilmaz O,Keleş S,Kiziltunç A,Odabaş AR,Cetinkaya R

doi

10.1007/s00296-001-0159-6

subject

Has Abstract

pub_date

2002-01-01 00:00:00

pages

149-52

issue

4

eissn

0172-8172

issn

1437-160X

journal_volume

21

pub_type

杂志文章
  • Defining functioning categories in axial Spondyloarthritis: the role of the ASAS Health Index.

    abstract::The Assessment of SpondyloArthritis international Society Health Index (ASAS HI) is an inclusive questionnaire, able to describe the total impairments and restrictions due to axial spondyloarthritis (axSpA). Considering the relationship between ASAS HI and the Ankylosing Spondylitis Disease Activity Score (ASDAS)-CRP,...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-016-3642-9

    authors: Di Carlo M,Lato V,Di Matteo A,Carotti M,Salaffi F

    更新日期:2017-05-01 00:00:00

  • High frequency of inflammatory back pain and other features of spondyloarthritis in patients with rheumatoid arthritis.

    abstract::The aim of this study was to investigate the frequency of patients with rheumatoid arthritis (RA) who have inflammatory back pain (IBP) and meet the existing classification criteria for ankylosing spondylitis (AS) and spondyloarthritis (SpA). We included 167 patients fulfilling the ACR 1987 revised criteria for RA. Af...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-012-2553-7

    authors: Can G,Solmaz D,Binicier O,Akar S,Birlik M,Soysal O,Akkoc N,Manisali M,Onen F

    更新日期:2013-05-01 00:00:00

  • Anti-Saccharomyces cerevisiae antibodies in patients with systemic lupus erythematosus.

    abstract::Anti-Saccharomyces cerevisiae antibodies (ASCA) had been known to be specific for Crohn's disease but it has been found in many other autoimmune diseases like systemic lupus erythematosus (SLE). Furthermore, cross-reactive epitopes on β2-glycoprotein I (β2GPI) and Saccharomyces cerevisiae were found in SLE patients. T...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-012-2431-3

    authors: Mankaï A,Sakly W,Thabet Y,Achour A,Manoubi W,Ghedira I

    更新日期:2013-03-01 00:00:00

  • A comparison of serum IL6 and CRP levels with respect to coronary changes and treatment response in Kawasaki disease patients: a prospective study.

    abstract::To evaluate serum levels of IL6 in patients with Kawasaki disease and compare it with CRP, and to assess the role of these biomarkers in predicting coronary changes and resistance to the first-line therapy of this disease in a subset of Indian population. A single centre prospective observational study was conducted a...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-019-04375-9

    authors: Nandi A,Pal P,Basu S

    更新日期:2019-10-01 00:00:00

  • Correlation of neurocognitive function and brain lesion load on magnetic resonance imaging in systemic lupus erythematosus.

    abstract::Neurocognitive dysfunction and brain injury on magnetic resonance imaging (MRI) are common in patients with systemic lupus erythematosus (SLE) and are associated with increased morbidity and mortality. However, brain MRI is expensive, is restricted by payers, and requires high expertise. Neurocognitive assessment is a...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-018-4080-7

    authors: Roldan PC,Jung RE,Sibbitt WL,Qualls CR,Flores RA,Roldan CA

    更新日期:2018-08-01 00:00:00

  • Thrombocytopenia as a presenting feature of Kawasaki disease: a case series from North India.

    abstract::Thrombocytosis is well described in children with Kawasaki disease (KD). We describe six children with KD who had thrombocytopenia at disease onset. This is an unusual finding and has clinical implications in the diagnosis of this condition. ...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-009-0947-y

    authors: Singh S,Gupta D,Suri D,Kumar RM,Ahluwalia J,Das R,Varma N

    更新日期:2009-12-01 00:00:00

  • Identification and purification of a 55K polypeptide in Sjögren's syndrome A antigen.

    abstract::The Sjögren's syndrome A antigen (SS-A) purified by affinity chromatography from human spleen was shown to contain a major polypeptide with a mol. wt. of 55 000 daltons confirmed as SS-A by its reactivity with different anti-SS-A sera on affinity columns, immunodiffusion and the Western blot. A similar reactive polype...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/BF00541183

    authors: Smith PR,Venables PJ,Williams D,Maini RN

    更新日期:1984-01-01 00:00:00

  • The effect of various disease-modifying anti-rheumatic drugs on the suppressive function of CD4⁺CD25⁺ regulatory T cells.

    abstract::Accumulating evidence suggests that defects in the function of CD4(+)CD25(+) regulatory T cells (Tregs) are important in immune-mediated diseases such as rheumatoid arthritis. Here, we investigated the effects of various disease-modifying anti-rheumatic drugs (DMARDs) on Treg function. Tregs and CD4(+)CD25(-) effector...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-012-2365-9

    authors: Oh JS,Kim YG,Lee SG,So MW,Choi SW,Lee CK,Yoo B

    更新日期:2013-02-01 00:00:00

  • The risk of serious infection in patients with rheumatoid arthritis treated with tumor necrosis factor inhibitors decreased over time: a report from the registry of Japanese rheumatoid arthritis patients on biologics for long-term safety (REAL) database.

    abstract::To investigate changes in the risk for serious infections (SIs) over time in Japanese rheumatoid arthritis (RA) patients treated with tumor necrosis factor inhibitors (TNFIs). This prospective cohort study included Japanese RA patients who began treatment with a TNFI from 2005 to 2007 (2005 group, n = 716, 634.2 patie...

    journal_title:Rheumatology international

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00296-014-3045-8

    authors: Sakai R,Cho SK,Nanki T,Koike R,Watanabe K,Yamazaki H,Nagasawa H,Amano K,Tanaka Y,Sumida T,Ihata A,Yasuda S,Nakajima A,Sugihara T,Tamura N,Fujii T,Dobashi H,Miura Y,Miyasaka N,Harigai M,REAL study group.

    更新日期:2014-12-01 00:00:00

  • Antibodies to arthritis-associated microbes in inflammatory joint diseases.

    abstract::IgM, IgG and IgA class antibodies against Yersinia, Salmonella, Campylobacter and Borrelia were determined by enzyme-linked immunosorbent assay (ELISA) in a group of 340 unselected patients with a recent inflammatory joint disease. The control group consisted of 340 and 100 healthy blood donors using Borrelia-ELISA an...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/BF02274884

    authors: Mäki-Ikola O,Viljanen MK,Tiitinen S,Toivanen P,Granfors K

    更新日期:1991-01-01 00:00:00

  • Paleopathological interpretations of hypermobility syndrome in the art from ancient America.

    abstract::Paleopathological representations of hypermobility syndrome were assumed in pre-Columbian artifacts from different ancient civilizations from America. Anthropomorphic sculptures from several museums and galleries visited on site or thru Internet show the human figure in contorted positions. These positions are only po...

    journal_title:Rheumatology international

    pub_type: 历史文章,杂志文章

    doi:10.1007/s00296-011-2007-7

    authors: Checa A

    更新日期:2012-10-01 00:00:00

  • Rheumatologic manifestations of histoplasmosis: a review.

    abstract::Histoplasmosis is an important cause of morbidity in endemic areas of the USA. Infection is often asymptomatic but can cause a broad spectrum of pathology. Less commonly, histoplasmosis can present with a wide-range of rheumatologic manifestations. The aim of this review is to provide a synopsis of the rheumatologic m...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s00296-013-2816-y

    authors: Sizemore TC

    更新日期:2013-12-01 00:00:00

  • Investigating the patient acceptable symptom state cut-offs: longitudinal data from a community cohort using the shoulder pain and disability index.

    abstract::This prospective study aimed to determine the patient acceptable symptom state (PASS) cut-off for the patient reported outcome measure shoulder pain and disability index (SPADI), and evaluate predictors of PASS achievement following standard shoulder care. Patients with shoulder pain, referred for shoulder ultrasound ...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-019-04486-3

    authors: Tran G,Dube B,Kingsbury SR,Tennant A,Conaghan PG,Hensor EMA

    更新日期:2020-04-01 00:00:00

  • Changes in synovial fluid biochemical markers following arthroscopic surgery in patients with knee osteoarthritis.

    abstract::Although arthroscopic surgery (AS) for knee osteoarthritis has been widely employed, scientific evidence is lacking. The purpose of this study was to investigate temporal changes in synovial fluid levels of biochemical markers associated with cartilage metabolism following AS. Twenty-five knees of 24 patients with med...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-012-2374-8

    authors: Nakajima A,Nakagawa K,Aoki Y,Sonobe M,Shibata Y,Yamazaki M,Murakami M

    更新日期:2013-01-01 00:00:00

  • Lung involvement in patients with primary Sjögren's syndrome: what are the predictors?

    abstract::The aim of this study was to investigate the prevalence, predictors and radiological findings of primary Sjögren's syndrome (pSS)-associated lung involvement. This retrospective cohort study included 123 patients with demographic, clinical, laboratory and radiological data who were diagnosed with pSS. Lung involvement...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-009-1152-8

    authors: Yazisiz V,Arslan G,Ozbudak IH,Turker S,Erbasan F,Avci AB,Ozbudak O,Terzioglu E

    更新日期:2010-08-01 00:00:00

  • Performance of subjects with knee osteoarthritis during walking: differential parameters.

    abstract::The effect of knee OA on kinetic and kinematic parameters during walking and standing is still controversial. Stability and energy consumption have not been well investigated in patients with OA. This research investigated the parameters distinguishing between the healthy subjects and patients with OA performance. It ...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-012-2639-2

    authors: Esrafilian A,Karimi MT,Amiri P,Fatoye F

    更新日期:2013-07-01 00:00:00

  • Associations with subregional BMD-measurements in patients with rheumatoid arthritis.

    abstract::Patients with rheumatoid arthritis (RA) have bone loss to various degrees at different skeletal sites. The subregional bone mineral density (BMD) of the hand and the correlation of BMD to other regional bone losses, parameters of inflammation or bone resorption was evaluated in 421 patients with RA and controls. RA pa...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-008-0638-0

    authors: Franck H,Gottwalt J

    更新日期:2008-11-01 00:00:00

  • Prevalence and risk factors of anxiety and depression in patients with systemic lupus erythematosus in Southwest China.

    abstract::Systemic lupus erythematosus (SLE) patients have high risk for anxiety and depression. We aimed to investigate the prevalence and risk factors of anxiety and depression in SLE patients in Southwest China. Participants were recruited by convenience sampling from Rheumatic Outpatient Clinic of West China Hospital Sichua...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-016-3559-3

    authors: Xie X,Wu D,Chen H

    更新日期:2016-12-01 00:00:00

  • Belimumab use, clinical outcomes and glucocorticoid reduction in patients with systemic lupus erythematosus receiving belimumab in clinical practice settings: results from the OBSErve Canada Study.

    abstract::To describe the characteristics of patients receiving belimumab, overall patterns of systemic lupus erythematosus (SLE) care, clinical outcomes, and changes in glucocorticoid dose following 6 months of therapy with belimumab, and healthcare resource utilization in belimumab users in Canadian clinical practice settings...

    journal_title:Rheumatology international

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00296-017-3682-9

    authors: Touma Z,Sayani A,Pineau CA,Fortin I,Matsos M,Ecker GA,Chow A,Iczkovitz S

    更新日期:2017-06-01 00:00:00

  • Prognostic indicators related to death in patients with Pneumocystis pneumonia associated with collagen vascular diseases.

    abstract::The objective of this study is to investigate the clinical markers of life-threatening Pneumocystis pneumonia (PCP) in patients with collagen vascular diseases (CVD). The patients who contracted Pneumocystis jeroveccii were retrospectively selected from our medical charts and conditions related to the patients' death ...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-009-0857-z

    authors: Aoki Y,Iwamoto M,Kamata Y,Nagashima T,Yoshio T,Okazaki H,Minota S

    更新日期:2009-09-01 00:00:00

  • Patients who underwent total hip or knee arthroplasty are more physically active than the general Dutch population.

    abstract::Total hip arthroplasty (THA) and total knee arthroplasty (TKA) bring relief of pain and functional disability to patients with end-stage osteoarthritis, and however, the literature on their impact on patients' level of physical activity (PA) is scarce. Cross-sectional study in patients who underwent THA/TKA surgery in...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-016-3598-9

    authors: Meessen JM,Peter WF,Wolterbeek R,Cannegieter SC,Tilbury C,Bénard MR,van der Linden HM,Onstenk R,Tordoir R,Vehmeijer SB,Verdegaal SH,Vermeulen HM,Nelissen RG,Vliet Vlieland TP

    更新日期:2017-02-01 00:00:00

  • The clinical significance of HRCT in evaluation of patients with rheumatoid arthritis-associated interstitial lung disease: a report from China.

    abstract::The objective of this study is to describe the interstitial lung disease (ILD) in rheumatoid arthritis (RA) patients of China, and to study clinical significance of high-resolution computed tomography (HRCT) in evaluation and treatment. One hundred and ten Chinese patients (79 women and 31 man) diagnosed with RA betwe...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-010-1665-1

    authors: Zou YQ,Li YS,Ding XN,Ying ZH

    更新日期:2012-03-01 00:00:00

  • Backpack-related musculoskeletal symptoms among Nigerian secondary school students.

    abstract::Musculoskeletal discomfort in schoolchildren is significantly related to the weight and mode of carrying backpack to school. Prevalence and patterns of musculoskeletal discomfort among Nigerian secondary school students carrying backpack was investigated. Systematic sampling technique was used in the selection of the ...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-014-2962-x

    authors: Hamzat TK,Abdulkareem TA,Akinyinka OO,Fatoye FA

    更新日期:2014-09-01 00:00:00

  • Accuracy, completeness and accessibility of online information on fibromyalgia.

    abstract::Fibromyalgia is a multi-factorial illness primarily characterised by widespread chronic pain and fatigue, with several symptoms and associated conditions. Due to a lack of clinical awareness and an absence of objective diagnostic measures, fibromyalgia patients often engage with online health information. The aim is t...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-019-04265-0

    authors: Basavakumar D,Flegg M,Eccles J,Ghezzi P

    更新日期:2019-04-01 00:00:00

  • Biomarkers of hand osteoarthritis.

    abstract::Hand osteoarthritis (OA) is a common degenerative joint disorder leading to substantial pain and disability. The most severe subtype is erosive hand OA characterized by an abrupt onset, local inflammation, subchondral erosions and worse outcomes than non-erosive disease. Biomarkers of hand OA could help to diagnose th...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s00296-017-3864-5

    authors: Lennerová T,Pavelka K,Šenolt L

    更新日期:2018-05-01 00:00:00

  • Single nucleotide polymorphisms of IL12B are associated with Takayasu arteritis in Chinese Han population.

    abstract::Takayasu arteritis (TA) is a rare autoimmune disease of unknown etiology. Genome-wide association studies (GWAS) have demonstrated association between genetic variants of IL12B and IL6 and TA. Since TA has been reported with ethnic heterogeneity, we sought to investigate whether the single-nucleotide-polymorphisms (SN...

    journal_title:Rheumatology international

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00296-016-3648-3

    authors: Wen X,Chen S,Li P,Li J,Wu Z,Li Y,Li L,Yuan H,Tian X,Zhang F,Li Y

    更新日期:2017-04-01 00:00:00

  • Current understanding and future perspectives of brain-heart-kidney axis in psoriatic arthritis.

    abstract::Psoriatic arthritis (PsA) patients are at a higher risk of systemic inflammatory sequelae, leading to microalbuminuria, cardiovascular (CVD) and neuropsychiatric (NPD) disease. Our aim is to present the existing literature about the relationship between CVD, kidney and NPD in PsA. The literature evaluation of PsA reve...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s00296-020-04633-1

    authors: Markousis-Mavrogenis G,Nurmohamed MT,Koutsogeorgopoulou L,Dimitroulas T,Katsifis G,Vartela V,Mitsikostas D,Kolovou G,Tektonidou M,Voulgari P,Sfikakis PP,Kitas GD,Mavrogeni SI

    更新日期:2020-09-01 00:00:00

  • Pattern of bone mineral density in idiopathic male osteoporosis.

    abstract::The mechanisms of male idiopathic osteoporosis are little known. We evaluated bone mineral loss by dual-energy X-ray absorptiometry and determined its cortical or trabecular nature in a cohort of men with idiopathic osteoporosis with fractures. Thirty-nine men (mean age 60 ± 13 years), with negative investigations for...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-011-2076-7

    authors: Laroche M

    更新日期:2012-10-01 00:00:00

  • Disease course and healthcare costs of a cohort of rheumatoid arthritis patients from Turkey.

    abstract::The objective of the study is to assess the disease course and associated healthcare costs in a cohort of established rheumatoid arthritis (RA) patients in Turkey. The study cohort consisted of 75 RA patients from our outpatient clinic who took part in a previous multicenter study assessing RA-related healthcare costs...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-020-04574-9

    authors: Ayan G,Esatoglu SN,Hatemi G,Hamuryudan V

    更新日期:2020-07-01 00:00:00

  • Serum serotonin levels and bone in rheumatoid arthritis patients.

    abstract::In rheumatoid arthritis (RA), a disease characterized by bone loss, increased levels of serotonin have been reported. Recent studies have demonstrated a role for circulating serotonin as a regulator of osteoblastogenesis, inhibiting bone formation. Thus, we measured serum serotonin levels (SSL) in a Portuguese sample ...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-017-3836-9

    authors: Bernardes M,Vieira T,Lucas R,Pereira J,Costa L,Simões-Ventura F,Martins MJ

    更新日期:2017-11-01 00:00:00