The clinical significance of HRCT in evaluation of patients with rheumatoid arthritis-associated interstitial lung disease: a report from China.

Abstract:

:The objective of this study is to describe the interstitial lung disease (ILD) in rheumatoid arthritis (RA) patients of China, and to study clinical significance of high-resolution computed tomography (HRCT) in evaluation and treatment. One hundred and ten Chinese patients (79 women and 31 man) diagnosed with RA between December 2008 to November 2009 were analyzed. According to the HRCT, 47 (42.73%) RA patients were diagnosed as ILD. Old age, smoking and pulmonary rales were closely related to ILD (P < 0.05). The main appearances of ILD were ground-glass (39.09%), honeycombing (4.55%), reticular patterns and consolidation (1.82%). Patients with reticular patterns and honeycombing were more likely to show the respiratory symptoms. It was also common to find other abnormal changes, such as fiber cord shadow (22.73%), lung markings fuzzy disorder (30%), pulmonary nodules (11.82%), emphysema (9.09%), bronchiectasis (3.64%), subpleural nodules (11.82%) and pleural thickening (24.55%). In treatment, honeycombing and subpleural nodules were more common in patients with methotrexate (MTX) and/or leflunomide treatment than without (P < 0.05). Other abnormal changes were no statistical significance (P > 0.05). Pulmonary involvement is common in RA patients, and it is suggested that HRCT could be a sensitive and useful way in evaluating the lung of RA patients.

journal_name

Rheumatol Int

authors

Zou YQ,Li YS,Ding XN,Ying ZH

doi

10.1007/s00296-010-1665-1

subject

Has Abstract

pub_date

2012-03-01 00:00:00

pages

669-73

issue

3

eissn

0172-8172

issn

1437-160X

journal_volume

32

pub_type

杂志文章
  • Investigation of the human FCRL1, 2, and 4 gene expressions in patients with rheumatoid arthritis.

    abstract::The Fc receptor-like (FCRL) molecules have recently been shown to contribute to the pathogenesis of certain autoimmune disorders. In this study, we investigated the expression levels of FCRL1, 2 and 4 in blood mononuclear cells from rheumatoid arthritis patients using real-time PCR. The mRNA of these molecules was det...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-016-3495-2

    authors: Khanzadeh A,Habibagahi Z,Hosseini A,Amirghofran Z

    更新日期:2016-08-01 00:00:00

  • Microscopic polyangiitis histologically confirmed by biopsy from nasal cavity and paranasal sinuses: a case report.

    abstract::Microscopic polyangiitis (MPA) is a systemic necrotizing vasculitis affecting small vessels without necrotizing granulomatous inflammation and is commonly associated with necrotizing glomerulonephritis. Diagnosis is based on typical clinical features, the presence of antimyeloperoxidase-antineutrophil cytoplasmic anti...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-006-0127-2

    authors: Kokan N,Hosomi Y,Inamoto S,Ohnishi K,Tanimoto H,Nibu K

    更新日期:2006-08-01 00:00:00

  • Mortality in patients with rheumatoid arthritis: a 15-year prospective cohort study.

    abstract::The aim of this study was to investigate (a) the mortality in a clinical cohort of patients with established rheumatoid arthritis in comparison with the general Dutch population over 15 years, (b) the trend in the mortality ratio during the study period, and (c) causes of death and compare these with the general popul...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-016-3638-5

    authors: van den Hoek J,Boshuizen HC,Roorda LD,Tijhuis GJ,Nurmohamed MT,van den Bos GA,Dekker J

    更新日期:2017-04-01 00:00:00

  • Effects of pulsed and sinusoid electromagnetic fields on human chondrocytes cultivated in a collagen matrix.

    abstract::Although several effects of electromagnetic fields (EMFs) on articular cartilage have been reported in recent studies, the use of EMFs to treat osteoarthritis remains a matter of debate. In an in vitro study, human chondrocytes harvested from osteoarthritic knee joints were released from their surrounding matrix and t...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-008-0565-0

    authors: Schmidt-Rohlfing B,Silny J,Woodruff S,Gavenis K

    更新日期:2008-08-01 00:00:00

  • Klippel-Feil syndrome misdiagnosed as spondyloarthropathy: case-based review.

    abstract::Spondyloarthropathy refers to any joint disease of the vertebral column, but the term is mainly used for a specific group of disorders called seronegative spondyloarthropathies (SpAs). The axial skeletal involvement, peripheral and extra-articular manifestations and an association with the major histocompatibility com...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s00296-019-04346-0

    authors: Čota S,Žagar I,Delimar V,Pap M,Perić D,Perić P

    更新日期:2019-09-01 00:00:00

  • Pro-brain natriuretic peptide (ProBNP) levels in North Indian children with Kawasaki disease.

    abstract::The diagnosis of Kawasaki disease (KD), a common pediatric vasculitis, is based solely on clinical criteria. There is a need for a robust laboratory marker that can help differentiate KD from other acute, febrile, childhood illnesses and also to predict cardiac involvement. We conducted a cross-sectional study of 25 c...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-016-3430-6

    authors: Reddy M,Singh S,Rawat A,Sharma A,Suri D,Rohit MK

    更新日期:2016-04-01 00:00:00

  • Does weather affect daily pain intensity levels in patients with acute low back pain? A prospective cohort study.

    abstract::The aim of this study was to investigate the influence of various weather parameters on pain intensity levels in patients with acute low back pain (LBP). We performed a secondary analysis using data from the PACE trial that evaluated paracetamol (acetaminophen) in the treatment of acute LBP. Data on 1604 patients with...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-015-3419-6

    authors: Duong V,Maher CG,Steffens D,Li Q,Hancock MJ

    更新日期:2016-05-01 00:00:00

  • Elevated levels of nitrate in rheumatoid arthritis.

    abstract::Nitric oxide (NO) is a free radical that plays important roles in many physiological and pathological processes. Evidence suggests that NO participates in the pathogenesis of inflammatory reactions in many autoimmune and inflammatory diseases such as rheumatoid arthritis (RA). The purpose of this study was to evaluate...

    journal_title:Rheumatology international

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/s002960100105

    authors: Onur O,Akinci AS,Akbiyik F,Unsal I

    更新日期:2001-05-01 00:00:00

  • The effects of exercise on lipid profile in systemic lupus erythematosus and healthy individuals: a randomized trial.

    abstract::The aim of the present study was to evaluate the effects of an exercise training program on lipid profile and composition of high-density lipoprotein (HDL) subfractions in systemic lupus erythematosus (SLE) patients and healthy controls. A 12-week, randomized trial was conducted. Thirty-three physically inactive SLE p...

    journal_title:Rheumatology international

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00296-014-3081-4

    authors: Benatti FB,Miossi R,Passareli M,Nakandakare ER,Perandini L,Lima FR,Roschel H,Borba E,Bonfá E,Gualano B,de Sá Pinto AL

    更新日期:2015-01-01 00:00:00

  • Circulating endothelial progenitor cells are reduced in SLE in the absence of coronary artery calcification.

    abstract::Circulating endothelial progenitor cells (EPCs) are reduced in patients with systemic lupus erythematosus (SLE). A reduced number of EPCs are associated with the presence of atherosclerosis in other populations. We sought to determine whether the reduction in EPC numbers in SLE is dependent on the presence of advanced...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-010-1730-9

    authors: Baker JF,Zhang L,Imadojemu S,Sharpe A,Patil S,Moore JS,Mohler ER 3rd,Von Feldt J

    更新日期:2012-04-01 00:00:00

  • Thrombocytopenia as a presenting feature of Kawasaki disease: a case series from North India.

    abstract::Thrombocytosis is well described in children with Kawasaki disease (KD). We describe six children with KD who had thrombocytopenia at disease onset. This is an unusual finding and has clinical implications in the diagnosis of this condition. ...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-009-0947-y

    authors: Singh S,Gupta D,Suri D,Kumar RM,Ahluwalia J,Das R,Varma N

    更新日期:2009-12-01 00:00:00

  • Systemic lupus erythematosus-related hypercalcemia with ectopic calcinosis.

    abstract::We report a case of a 39-year-old female with active systemic lupus erythematosus who complained of lethargy and weakness with a moderate renal impairment. Hypercalcemia was confirmed by laboratory examination. Her X-ray revealed significant ectopic calcinosis in subcutaneous tissue of bilateral hands, and Tc-99(m) me...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s00296-016-3486-3

    authors: Zhao L,Huang L,Zhang X

    更新日期:2016-07-01 00:00:00

  • The sensitivity, specificity and accuracy of anti-citrulline antibody test in diagnosis of rheumatoid arthritis.

    abstract::Citrulline antibody, nowadays, is a new item which has been the center of attention due to its much more specificity to diagnose RA. The aim of the present study was to evaluate the efficacy and accuracy of anti-citrulline antibody test in RA diagnosis among hospitalized patients in Iran. Through a case-control study,...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-012-2469-2

    authors: Abolghasemi S,Gitipour A,Morteza A

    更新日期:2013-04-01 00:00:00

  • The role of genetics and epigenetics in rheumatic diseases: are they really a target to be aimed at?

    abstract::To date, numerous genetic and epigenetic studies have been performed and provided a crucial step forward in our understanding of the pathogenesis of rheumatic diseases. However, most of the recent advances in the treatment of rheumatic diseases including biological therapies are not based on or even discrepant from th...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s00296-018-4026-0

    authors: Kato M,Yasuda S,Atsumi T

    更新日期:2018-08-01 00:00:00

  • Enzyme-linked immunosorbent assays for antibodies to poly(A), poly dAT and histones: possibly useful tools for the evaluation of prognosis and disease activity in systemic lupus erythematosus.

    abstract::In a prospective study 222 sera from 56 patients with systemic lupus erythematosus (SLE) were tested for antibodies to poly(A), poly dAT and histones using enzyme-linked immunosorbent assay (ELISA). Patients with active disease had significantly more often antibodies to poly(A), poly dAT and histones than patients wit...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/BF00541200

    authors: Helve T,Gripenberg M,Kurki P,Teppo AM,Wegelius O

    更新日期:1984-01-01 00:00:00

  • 2017 update of the Turkish League Against Rheumatism (TLAR) evidence-based recommendations for the management of knee osteoarthritis.

    abstract::In a Turkish League Against Rheumatism (TLAR) project, evidence-based recommendations for the management of knee osteoarthritis (OA) was developed for the first time in our country in 2012 (TLAR-2012). In accordance with developing medical knowledge and scientific evidence, recommendations were updated. The committee ...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s00296-018-4044-y

    authors: Tuncer T,Cay FH,Altan L,Gurer G,Kacar C,Ozcakir S,Atik S,Ayhan F,Durmaz B,Eskiyurt N,Genc H,GokceKutsal Y,Gunaydin R,Hepguler S,Hizmetli S,Kaya T,Kurtais Y,Saridogan M,Sindel D,Sutbeyaz S,Sendur OF,Ugurlu H,Un

    更新日期:2018-08-01 00:00:00

  • Ultrasound-guided retro-calcaneal bursa corticosteroid injection for refractory Achilles tendinitis in patients with seronegative spondyloarthropathy: efficacy and follow-up study.

    abstract::Ultrasound (US)-guided corticosteroid injection has been shown to be safe and effective for varied causes of plantar fasciitis; however, its use for Achilles tendinitis is controversial. We studied the efficacy and changes in US findings at Achilles enthesitis after corticosteroid injection in patients with spondyloar...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-016-3440-4

    authors: Srivastava P,Aggarwal A

    更新日期:2016-06-01 00:00:00

  • Renal thrombotic microangiopathies/thrombotic thrombocytopenic purpura in a patient with primary Sjögren's syndrome complicated with IgM monoclonal gammopathy of undetermined significance.

    abstract::Thrombotic microangiopathy (TMA)/thrombotic thrombocytopenic purpura (TTP) is a rare but potentially lethal condition requiring rapid recognition, diagnosis, and initiation of therapy. We experienced a case of a 61-year-old woman with primary Sjögren's syndrome (pSS) complicated with severe renal TMA/TTP following IgM...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-010-1569-0

    authors: Koga T,Yamasaki S,Nakamura H,Kawakami A,Furusu A,Taguchi T,Eguchi K

    更新日期:2013-01-01 00:00:00

  • Mechanisms of oxyradical production in substance P stimulated rheumatoid synovial cells.

    abstract::We examined the intracellular mechanisms of substance P induced oxyradical production in rheumatoid synovial cells by the luminol-dependent chemiluminescence method. After stimulation with substance P (30 microM), single synovial A (macrophage-like) or B (fibroblast-like) cells released oxyradicals such as superoxide ...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/BF01419729

    authors: Tanabe T,Otani H,Mishima K,Ogawa R,Inagaki C

    更新日期:1996-01-01 00:00:00

  • Incidence of herpes zoster infections in juvenile idiopathic arthritis patients.

    abstract::The risk of herpes zoster among patients with juvenile idiopathic arthritis (JIA) exposed to biologics has not been evaluated. We determined incidence rates of herpes zoster among children with JIA in correlation with medication at time of occurrence and total drug exposure. The German biologics register database was ...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-014-3197-6

    authors: Nimmrich S,Horneff G

    更新日期:2015-03-01 00:00:00

  • Interleukin-17 pathways in systemic sclerosis-associated fibrosis.

    abstract::Fibrosis is unregulated tissue repair that may cause impairment of organ function, especially in end-organ damage. Systemic sclerosis (SSc) is the prototype systemic fibrosing disorder. Classical targets for fibrosis in SSc like transforming growth factor Beta (TGF-β), Interleukin-6 (IL-6), and multiple tyrosine kinas...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s00296-019-04317-5

    authors: Ahmed S,Misra DP,Agarwal V

    更新日期:2019-07-01 00:00:00

  • Synovial tissue rank ligand expression and radiographic progression in rheumatoid arthritis: observations from a proof-of-concept randomized clinical trial of cytokine blockade.

    abstract::The objective of the study was to evaluate synovial tissue receptor activator of nuclear factor-κβ ligand (RANKL) and osteoprotegerin (OPG) as biomarkers of disease activity, progressive joint damage, and therapeutic response, during cytokine blockade in rheumatoid arthritis (RA). Patients with active RA entered a ran...

    journal_title:Rheumatology international

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00296-009-1191-1

    authors: Rooney T,Edwards CK 3rd,Gogarty M,Greenan L,Veale DJ,FitzGerald O,Dayer JM,Bresnihan B

    更新日期:2010-11-01 00:00:00

  • Higher levels of serum interleukin-35 are associated with the severity of pulmonary fibrosis and Th2 responses in patients with systemic sclerosis.

    abstract::The aim of the study is to investigate the levels of serum interleukin-35 (IL-35) before and after treatment and its relationship with clinical parameters as well as the frequency of different subsets of CD4+ T cells in patients with systemic sclerosis (SSc) to explore the role of IL-35 in the pathogenesis of SSc. The...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-018-4071-8

    authors: Tang J,Lei L,Pan J,Zhao C,Wen J

    更新日期:2018-08-01 00:00:00

  • Sarcopenia in systemic sclerosis: the impact of nutritional, clinical, and laboratory features.

    abstract::We evaluated the presence of sarcopenia in a population of systemic sclerosis (SSc) patients, with respect to nutritional, clinical, and laboratory features. A total of 62 patients who met the ACR/EULAR 2013 classification criteria were enrolled. Sarcopenia was defined according to the Relative Skeletal Mass Index (RS...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-019-04401-w

    authors: Corallo C,Fioravanti A,Tenti S,Pecetti G,Nuti R,Giordano N

    更新日期:2019-10-01 00:00:00

  • Association of the IRF5 rs2004640 polymorphism with rheumatoid arthritis: a meta-analysis.

    abstract::Several molecular epidemiological studies have been conducted in recent years to evaluate a possible association between the interferon regulatory factor 5 (IRF5) rs2004640 polymorphism and rheumatoid arthritis risk in diverse populations. However, the results remain conflicting rather than conclusive. Our aim was to ...

    journal_title:Rheumatology international

    pub_type: 杂志文章,meta分析

    doi:10.1007/s00296-013-2806-0

    authors: Jia X,Hu M,Lin Q,Ren H

    更新日期:2013-11-01 00:00:00

  • Bisphosphonate-related osteonecrosis of the jaw in non-malignant bone disease.

    abstract::Bisphosphonates such as alendronate, risedronate and zoledronate have revolutionised the treatment for osteoporosis and Paget's disease. These drugs reduce fracture risk and probably mortality in patients with osteoporosis. However, they have a long in vivo half-life following cessation and may be associated with dela...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s00296-013-2771-7

    authors: Wong PK,Borromeo GL,Wark JD

    更新日期:2013-09-01 00:00:00

  • The effect of gold treatment on monocyte interleukin-1 production in rheumatoid arthritis. A prospective study.

    abstract::Monocyte interleukin-1 (IL-1) production in vitro was studied in 49 patients with rheumatoid arthritis (RA) and 31 controls. Twenty-six of the RA patients were studied prospectively for up to 12 months after beginning chrysotherapy. About half of the patients (group 1) exhibited pretreatment levels of monocyte IL-1 se...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/BF02274840

    authors: Danis VA,Kulesz AJ,Kelly DE,Nelson DS,Brooks PM

    更新日期:1990-01-01 00:00:00

  • Binding of antibodies raised against tumour necrosis factor alpha (TNF alpha) to blood vessels and macrophages in inflamed synovial tissue.

    abstract::The distribution of tumour necrosis factor alpha (TNF alpha) in rheumatoid synovium has been investigated. Ten rheumatoid synovia were compared with seven normal synovia and a range of other tissues, using one polyclonal and six monoclonal antibodies. A common staining pattern was obtained with five reagents. Absence ...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/BF00290246

    authors: Wilkinson LS,Edwards JC

    更新日期:1991-01-01 00:00:00

  • Can clodronate be effective in the treatment of disabling hydroxyapatite crystal-deposition disease? A report of two cases.

    abstract::Hydroxyapatite crystals are often deposited in the vicinity of joints, where they can cause a clinical periarthritis. Clodronate is a first-generation bisphosphonate that has the ability to reduce ectopic calcifications. Two women were affected by disabling calcific periarthritis of the shoulders lasting for years and...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-010-1575-2

    authors: Saviola G,Abdi-Ali L,Baiardi P,Benucci M

    更新日期:2011-03-01 00:00:00

  • Specific antigen and antibody to Mycobacterium leprae in the cryoprecipitate of a patient with Lucio phenomenon.

    abstract::Using a sensitive and specific enzyme-linked immunosorbent assay (ELISA) assay we showed that the cryoglobulins of a patient with Lucio phenomenon contain phenolic glycolipid I antigen and a specific antibody. ...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/BF00541512

    authors: Drosos AA,Brennan PJ,Elisaf MS,Stefanou SG,Papadimitriou CS,Moutsopoulos HM

    更新日期:1986-01-01 00:00:00