Abstract:
:The Sjögren's syndrome A antigen (SS-A) purified by affinity chromatography from human spleen was shown to contain a major polypeptide with a mol. wt. of 55 000 daltons confirmed as SS-A by its reactivity with different anti-SS-A sera on affinity columns, immunodiffusion and the Western blot. A similar reactive polypeptide was demonstrated in extracts of rabbit liver, brain, spleen, kidney, lung and thymus.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Smith PR,Venables PJ,Williams D,Maini RNdoi
10.1007/BF00541183subject
Has Abstractpub_date
1984-01-01 00:00:00pages
135-8issue
3eissn
0172-8172issn
1437-160Xjournal_volume
4pub_type
杂志文章abstract::Alkoptunuria is an inherited autosomal recessive metabolic disorder which is caused by the lack of homogentisic acid-oxidase enzyme. It is associated with various systemic abnormalities and related to the deposition of homogentisic acid pigment in connective tissues. These pigmentary changes are termed "ochronosis". W...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-004-0538-x
更新日期:2005-08-01 00:00:00
abstract::We studied the relationships between physician-assessed damage, severity and activity in a large, multicentre systemic sclerosis (SSc, scleroderma) cohort. We hypothesized that there is a relationship between disease activity and severity and damage, but that severity would be more strongly related to damage. A total ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-1129-7
更新日期:2010-07-01 00:00:00
abstract::The assessment of skin fibrosis is vital for the diagnosis and monitoring of treatment in the systemic sclerosis (SSc)-a severe autoimmune disease. The elastography is a technique of skin fibrosis assessment through the evaluation of skin strain. We compared the efficacy of the shear wave elastography (SWE) and common...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-020-04539-y
更新日期:2020-05-01 00:00:00
abstract::A total of 95 patients suffering from active rheumatoid arthritis were included in this double-blind, placebo-controlled study of the immunomodulator OM-8980. Treatment was one capsule daily of OM-8980 or placebo for 6 months. A significant improvement was observed in the OM-8980 group in comparison with the placebo g...
journal_title:Rheumatology international
pub_type: 临床试验,杂志文章
doi:10.1007/BF00270248
更新日期:1989-01-01 00:00:00
abstract::Takayasu's arteritis (TA) is a rare chronic vasculitis of the aorta and its main branches. Infectious agents or autoimmunity are thought to influence the pathophysiology. Ethnic preponderance in East Asia and usually affects young Asian women suggesting a possible role of genetic factor in the etiology. We present a r...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-1234-7
更新日期:2011-06-01 00:00:00
abstract::A 7-year-old child was first admitted for persistent fever of 15-day duration and suspected meningitis. Kawasaki syndrome was lately diagnosed upon the recognition of an extensive diffuse coronary artery damage characterized by medium-sized aneurysms of the epicardial vessels. An eccentric thrombus along the inferior ...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-011-1814-1
更新日期:2012-03-01 00:00:00
abstract::To evaluate the correlation between measurements of antinuclear antibodies serum levels by enzyme immunoassay (ANA-EIA), and the degree of systemic lupus erythematosus disease activity. To retest the performance of the test compared to measurement of antinuclear antibodies by immunofluorescence (ANA-IIF). Eighty-five ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-007-0324-7
更新日期:2007-08-01 00:00:00
abstract::Folate supplementation is widely accepted and utilized for the prevention of adverse events in juvenile idiopathic arthritis (JIA) patients who are treated with methotrexate. Despite the widespread use of folate supplementation, there is a lack of convincing evidence to support the role of folate in the enhancement of...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-013-2696-1
更新日期:2013-09-01 00:00:00
abstract::Uveitis may represent an opportunity to diagnose spondyloarthropathies (SpA) earlier and influence treatment decisions. We describe the percentage of acute anterior uveitis (AAU) in a diverse group of SpA patients seen at one academic setting and compare demographic and clinical characteristics according to the presen...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-019-04386-6
更新日期:2019-09-01 00:00:00
abstract::The aim of this study was to evaluate the effectiveness of intravenous corticosteroid therapy when Henoch-Schönlein purpura (HSP) patients are unable to tolerate oral medications due to abdominal pain. We retrospectively analyzed 111 children with a diagnosis of HSP (mean age 6.9 ± 2.3 years, male:female = 54:57) from...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1507-1
更新日期:2011-11-01 00:00:00
abstract::We describe a patient with bronchiolitis obliterans organizing pneumonia (BOOP) requiring respiratory support and treated with corticosteroids and cytoxan for presumed Wegener's granulomatosis (WG). The diagnosis of WG was based on clinical presentation and strongly positive stains for anti-neutrophilic cytoplasmic an...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s002960000095
更新日期:2001-04-01 00:00:00
abstract::Previous studies have demonstrated an increased risk of breast cancer among patients with systemic sclerosis (scleroderma). To describe the clinical characteristics of 21 patients with both systemic sclerosis and breast cancer, and compare their risk factors to female scleroderma patients without breast cancer, in a p...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0540-9
更新日期:2008-07-01 00:00:00
abstract::The aim of the study was to compare the diagnostic efficacy of the visual assessment of diffusion-weighted imaging (DWI) and dynamic contrast-enhanced (DCE) sequences compared to the STIR sequence in the diagnostics of active sacroiliitis in the course of axial spondyloarthritis (axSpA). The study group consisted of 4...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-019-04373-x
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate the adequacy of the following criteria for the classification of juvenile-onset spondyloarthropathies (JSpA): European Spondyloarthropathy Study Group criteria (ESSGCr) and Amor criteria (ACr) (proposed for adult SpA), Garmisch-Partenkirchen (G-PCr), seronegative enthe...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-004-0460-2
更新日期:2005-08-01 00:00:00
abstract::Baseline and sequential liver biopsies were performed in ten patients with rheumatoid arthritis (RA) treated with methotrexate (MTX) for more than 4 years. Liver biopsies were performed in all patients before the initiation of MTX therapy and were repeated after reaching a cumulative dose of 1500 mg or more. In four p...
journal_title:Rheumatology international
pub_type: 临床试验,杂志文章
doi:10.1007/BF00246875
更新日期:1992-01-01 00:00:00
abstract::When rheumatoid articular cartilage samples were incubated with normal peripheral blood monocytes and cultured synovial cells in the presence of recombinant human interleukin-1 (IL-1) in vitro, large numbers of monocytes were seen to be attached to the articular surface. Significant numbers of monocytes invaded the ca...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00290248
更新日期:1991-01-01 00:00:00
abstract::To determine the forms and characteristics of rheumatic diseases whose initial presentation mimics septic arthritis. Retrospective study of 398 patients hospitalized between 1979 and 2005 for arthritis diagnosed and treated as septic. In 10 cases, initial presentation of a rheumatic disease was highly suggestive of se...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-012-2364-x
更新日期:2013-08-01 00:00:00
abstract::Biological markers of inflammation are useful for the diagnosis and monitoring of inflammatory rheumatic diseases. The present study tested, whether serum amyloid A (SAA) could be used as a marker of inflammatory disease activity in ankylosing spondylitis (AS). In 72 patients with AS, the two valuable surrogate marker...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s002960050114
更新日期:2000-01-01 00:00:00
abstract::The present cross-sectional data demonstrate cardiovascular (CV) risk in patients with rheumatoid arthritis (RA). The cross-sectional data were part of an interventional trial that included 100 patients with defined RA. Traditional CV risk parameters and risk score calculation for the German population were used to as...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-011-2238-7
更新日期:2012-12-01 00:00:00
abstract::Nailfold videocapillaroscopy was performed in 21 controls (C) and 21 patients (P) with systemic lupus erythematosus (SLE) classified according to the American College of Rheumatology, with, at least, 1 year of diagnosed disease and having low activity (MEX-SLEDAI) and sequel (SLICC) indexes at the time of the examinat...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-005-0033-z
更新日期:2006-05-01 00:00:00
abstract::To validate the Thai language version of the Psoriasis Epidemiology Screening Tool (PEST) and the Early Arthritis for Psoriatic Patients Questionnaire (EARP), as well as also to develop a new tool for screening psoriatic arthritis (PsA) among psoriasis (Ps) patients. This was a cross-sectional study. Ps patients visit...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-016-3513-4
更新日期:2016-10-01 00:00:00
abstract::The expressions of some terminal glycotopes of synovial immunoglobulins G, A, and M were analysed in relation to rheumatoid arthritis (RA) progression defined according to early and advanced radiological changes in patients' hands. The relative amounts of terminal monosaccharides were determined by lectin-immunoblotti...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-1139-5
更新日期:2010-08-01 00:00:00
abstract::Immunofluorescence on polymorphonuclear cells (PMN) of patients with Felty syndrome (FS) revealed increased amounts of IgG, IgA, and IgM bound to the PMN surface compared with PMN of patients with rheumatoid arthritis alone. A positive correlation was found between the score for surface-bound immunoglobulins on FS-PMN...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00541352
更新日期:1985-01-01 00:00:00
abstract::We describe the case of a 59 year old man with systemic sclerosis and superficial siderosis of the central nervous system characterized by progressive worsening of walking with signs of pyramidal liberation associated with cerebellar ataxia and bilateral hypoacusia. Ferritin and oligoclonal bands were found on lumbar ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0523-x
更新日期:2008-06-01 00:00:00
abstract::The aim of this study was to evaluate the total antioxidant status (TAS), total oxidative status (TOS) and oxidative stress index (OSI) in patients with postmenopausal osteoporosis. We also investigate the relation between bone mineral density and oxidative/antioxidative parameters. Thirty-nine patients with osteoporo...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-007-0452-0
更新日期:2008-02-01 00:00:00
abstract::While carpal tunnel syndrome (CTS) is the most common entrapment neuropathy presented at rheumatologic consultation, its ulcerative variant is rarely described. We report of a case of severe bilateral medial nerve palsy, presented to us for diagnosis of chronic digital ulcers which had been suspected to be rheumatolog...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-1229-4
更新日期:2011-05-01 00:00:00
abstract::The current clinical and laboratory parameters of Takayasu arteritis (TA) are insufficient for proper assessment of disease activity. The aims of this study were to investigate the markers of endothelial injury and repair, including circulating endothelial cell (CEC), circulating endothelial progenitor cell (CEPC) and...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-013-2937-3
更新日期:2014-08-01 00:00:00
abstract::Antibodies to citrullinated proteins have been described in patients with rheumatoid arthritis (RA) and these appear to be the most specific markers of the disease. Our objective was to determine the frequency of antibodies to cyclic citrullinated peptides (CCPs) in patients with RA and the association of anti-CCP ant...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0570-3
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to analyze the expression of apoptosis-related molecules in rheumatoid arthritis (RA) synovium, with special emphasis on the apoptosis accelerator Bax. METHODS:Immunohistochemical analysis of Bax, Bcl-2, and Bcl-x(L) was performed in tissue specimens of patients with RA and compared...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-002-0255-2
更新日期:2003-03-01 00:00:00
abstract::Patients with rheumatoid arthritis (RA) are at increased risk of low bone density and fractures. This study identifies predictors of initiation of dual energy X-ray absorptiometry (DXA) testing in RA. We identified RA patients from the CORRONA registry with >or=1 year follow-up without reported DXA at study entry. The...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0804-4
更新日期:2009-06-01 00:00:00