Abstract:
:We describe a patient with bronchiolitis obliterans organizing pneumonia (BOOP) requiring respiratory support and treated with corticosteroids and cytoxan for presumed Wegener's granulomatosis (WG). The diagnosis of WG was based on clinical presentation and strongly positive stains for anti-neutrophilic cytoplasmic antibodies (cANCA). The results of an open-lung biopsy were consistent with BOOP. Although BOOP has previously been described as one of the pulmonary manifestations of WG, other more specific histologic features of WG such as capillaritis or necrotizing vasculitis were lacking. Because influenza A virus was cultured from the patient's lung tissue, final assessment of the illness focused on this as the etiologic agent triggering the pulmonary syndrome. The presence of ANCA was considered to be nonspecific. The patient's condition improved with appropriate therapy for BOOP.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Staud R,Ramos LGdoi
10.1007/s002960000095subject
Has Abstractpub_date
2001-04-01 00:00:00pages
125-8issue
3eissn
0172-8172issn
1437-160Xjournal_volume
20pub_type
杂志文章abstract:BACKGROUND:There is an overall increased risk of adverse pregnancy outcomes and maternal morbidity in patients with most autoimmune rheumatic diseases (ARD); outcomes are generally improved when the pregnancy is planned and the disease is in control. OBJECTIVE:The objective of the present study was to describe the sex...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-020-04679-1
更新日期:2021-02-01 00:00:00
abstract::The presence of specific anti-Proteus antibodies in active, rheumatoid arthritis (RA) patients, has been demonstrated by four different techniques: indirect bacterial agglutination, ELISA, Western blotting and immunofluorescence. Furthermore, anti-HLA-DR4 tissue typing sera have been shown to bind to Proteus microorga...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/BF00271885
更新日期:1989-01-01 00:00:00
abstract::The aim of this study is to determine whether and to which extent pentosidine (PEN) is influenced in the case of advanced osteoarthritis (OA) in urine and in some tissues. Reverse phase HPLC method for PEN determination with fluorescence monitoring was utilized. Urinary pentosidine (U-PEN) and pyridinoline (U-PD) were...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-006-0105-8
更新日期:2006-08-01 00:00:00
abstract:OBJECTIVE:The present study was performed to localize the articular deposition of monosodium urate (MSU) crystal in joints. We compare the detection efficiencies of dual-energy CT (DECT) and ultrasound scans. METHODS:Analyses by DECT and ultrasound were performed with 184 bilateral joints of the lower limbs of 54 cons...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-018-3994-4
更新日期:2018-05-01 00:00:00
abstract::Women in reproductive age with rheumatic diseases (RD) are especially vulnerable for depression and anxiety which negatively impacts the pregnancy, birth, and RD. The purpose of this study is to describe the frequency of anxiety and depression symptoms employing the Hospital Anxiety and Depression Scale (HADS) in wome...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-020-04591-8
更新日期:2020-09-01 00:00:00
abstract::The purpose of this study was to detect the frequency of inflammatory cervical spine changes and characteristic features such as resorption in rheumatoid arthritis (RA) with arthritis mutilans (AM) hand deformity. The series included 23 patients with AM hand deformity who fulfilled the 1987 American Rheumatism Associa...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s002960100114
更新日期:2001-08-01 00:00:00
abstract::The role of free radicals in fibromyalgia is controversial. In this study, 85 female patients with primary fibromyalgia and 80 age-, height-, and weight-matched healthy women were evaluated for oxidant/antioxidant balance. Malondialdehyde is a toxic metabolite of lipid peroxidation used as a marker of free radical dam...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-003-0427-8
更新日期:2005-04-01 00:00:00
abstract::An immunoglobulin-independent deposition of the complement (C) components C4 and C3 occurs on rat kidney medullary structures, when sera of patients with various inflammatory diseases are studied by indirect immunofluorescence. The diagnostic value of this new test (C4-C3-IFT) for polymyalgia rheumatica (PMR) is stres...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00271838
更新日期:1988-01-01 00:00:00
abstract::Behçet's disease (BD) is a multi-system inflammatory disorder, in which cytokine balance is polarized to Th1. In this study, the cell surface molecule expression, Th1/Th2, inflammatory cytokine levels in blood, and synovial fluid of CD3(+) T lymphocytes in BD were investigated. The study group consisted of 10 BD, 10 a...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-012-2446-9
更新日期:2013-03-01 00:00:00
abstract::Autophagosomes are formed during autophagy, which is activated by hypoxia and starvation. Autophagy is important for mast cell degranulation. We hypothesized that autophagy is a key feature in the pathogenesis of systemic sclerosis (SSc). We examined SSc clinical features and mast cell density across the presence and ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-013-2827-8
更新日期:2014-03-01 00:00:00
abstract::Previous studies showed a link between systemic lupus erythematosus (SLE) and Epstein-Barr virus (EBV) infection. We sought to determine the features of serologic response to EBV in SLE patients and whether this response differs from those of systemic sclerosis (SSc) and primary antiphospholipid syndrome (PAPS) patien...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1573-4
更新日期:2012-01-01 00:00:00
abstract::This study was designed to determine the effects of the osteoprotegerin (OPG) on the mRNA expression of carbonic anhydrase II (CAII) and the receptor activator of NF-κB (RANK) in mouse osteoclast-like cells. Marrow cells were harvested from femora and tibiae of mouse and cultured in 6-well chamber slides. After 1 day ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-011-2338-4
更新日期:2012-12-01 00:00:00
abstract::Circulating endothelial progenitor cells (EPCs) are reduced in patients with systemic lupus erythematosus (SLE). A reduced number of EPCs are associated with the presence of atherosclerosis in other populations. We sought to determine whether the reduction in EPC numbers in SLE is dependent on the presence of advanced...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1730-9
更新日期:2012-04-01 00:00:00
abstract::Previous studies have shown that fibromyalgia syndrome (FMS) is associated with low level of physical activity and exercise, which may lead to an increased risk of osteoporosis. However, studies of bone mineral density (BMD) in fibromyalgia have shown conflicting results. Thus, we conducted a systematic review and met...
journal_title:Rheumatology international
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00296-016-3625-x
更新日期:2017-04-01 00:00:00
abstract::The aim of the present study was to evaluate the effect of long-term leflunomide and methotrexate (MTX) therapy during the course of rheumatoid arthritis (RA) estimated by digital X-ray radiogrammetry (DXR) and computer-aided joint space analysis (CAJSA) as diagnostic tools for the quantification of disease-related pe...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0682-9
更新日期:2009-01-01 00:00:00
abstract::Isoform 4 of the human peptidylarginine deiminase (hPAD4) enzyme may be responsible for the citrullination of antigens in rheumatoid arthritis (RA) and has been shown to be itself the target of disease-specific autoantibodies. Here, we have tested whether the level of serum anti-hPAD4 antibodies in RA patients is stab...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1765-y
更新日期:2012-05-01 00:00:00
abstract::Fibromyalgia syndrome is characterized by chronic generalized pain accompanied by a broad symptomatologic spectrum. Besides chronic fatigue, sleep disturbances, headaches and cognitive dysfunction that are extensively described in the literature, a considerable proportion of patients with fibromyalgia experience gastr...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-014-3109-9
更新日期:2015-03-01 00:00:00
abstract::Seven females and one male with almost identical sclerotic and hyperostotic changes of the manubrium sterni are reported. The clinical course was prolonged and characterized by intermittent periods of exacerbation followed by improvement. Malignancies, bacterial inflammatory processes, and Paget disease, which were fi...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00541284
更新日期:1986-01-01 00:00:00
abstract::Neurocognitive dysfunction and brain injury on magnetic resonance imaging (MRI) are common in patients with systemic lupus erythematosus (SLE) and are associated with increased morbidity and mortality. However, brain MRI is expensive, is restricted by payers, and requires high expertise. Neurocognitive assessment is a...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-018-4080-7
更新日期:2018-08-01 00:00:00
abstract::Primary Sjögren syndrome (pS) is associated with autoantibodies such as rheumatoid factor (RF) and anti-nuclear antibodies such as anti-Ro (SS-A) and/or La (SS-B). Recent developments within autoimmune diagnostics allow quantitation of RF subclasses and anti-Ro epitopes. Will this refinement by autoimmune diagnostics ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-018-4090-5
更新日期:2018-08-01 00:00:00
abstract::To establish whether a cadaver model can serve as an effective surrogate for the detection of tendon damage characteristic of rheumatoid arthritis (RA). In addition, we evaluated intraobserver and interobserver agreement in the grading of RA-like tendon tears shown by US, as well as the concordance between the US find...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-016-3460-0
更新日期:2016-06-01 00:00:00
abstract::A 50-year-old man presented with a complaint of low-back pain and widespread joint pain for the previous 20 years. Conventional radiography revealed wide areas of calcification in the intervertebral discs and degenerative changes in the peripheral joints. A diagnosis of ochronosis was made by the observation of bluish...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-007-0381-y
更新日期:2007-11-01 00:00:00
abstract::Splenectomy may be necessary to treat systemic lupus erythematosus (SLE) patients with thrombocytopenia; however, whether performing a splenectomy on patients without SLE increases the subsequent risk of SLE remains unknown. Therefore, this study was conducted to determine the association between splenectomy and SLE. ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-015-3388-9
更新日期:2016-02-01 00:00:00
abstract::Agalactosyl IgG [Gal(0)] was first discovered in patients with rheumatoid arthritis (RA). However, the proportion of this glycoform is also raised in tuberculosis and leprosy. This has helped reinforce the suggestion that RA may be triggered by a mycobacterium-like slow bacterial infection. On the other hand, arthriti...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00262090
更新日期:1995-01-01 00:00:00
abstract::The case of a 29-year-old white female with a 7-year history of typical scleroderma is presented who developed excessive fibrosis of the supraclavicular lymph nodes. After 3 years of disease, firm right supraclavicular lymphadenopathy appeared, accompanied by a high fever. Biopsy revealed non-caseating granulomas and ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00301013
更新日期:1993-01-01 00:00:00
abstract::Acute pseudogout of the neck, also known as the crowned dens syndrome, is a rare cause of neck pain characterised by crystalline deposition in periodontoid articular tissues. It is typified clinically by severe cervical pain and stiffness, often in conjunction with pyrexia and raised inflammatory markers. As such, it ...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-009-1145-7
更新日期:2011-01-01 00:00:00
abstract::A total of 95 patients suffering from active rheumatoid arthritis were included in this double-blind, placebo-controlled study of the immunomodulator OM-8980. Treatment was one capsule daily of OM-8980 or placebo for 6 months. A significant improvement was observed in the OM-8980 group in comparison with the placebo g...
journal_title:Rheumatology international
pub_type: 临床试验,杂志文章
doi:10.1007/BF00270248
更新日期:1989-01-01 00:00:00
abstract::The study objective was to examine natural variation of the patient-reported outcome measures fatigue, pain, patient global assessment (PaGl) and the Bath Ankylosing Spondylitis Functional Index (BASFI) in patients with stable axial spondyloarthropathy (ax-SpA) defined on the basis of the Bath Spondylitis Ankylosing D...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-017-3920-1
更新日期:2018-03-01 00:00:00
abstract::We sought to determine the prevalence of additional connective tissue diseases (CTDs) in patients with idiopathic inflammatory myopathies (IIM), and to study the muscle biopsy patterns in various clinico-serologic subsets of myositis. We undertook a retrospective cohort study of 648 patients with a histological diagno...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-019-04411-8
更新日期:2019-10-01 00:00:00
abstract::Chronic inflammatory syndromes such as rheumatoid arthritis (RA) are associated with high frequencies of CD4+CD28- T cells. The number of these cells is genetically determined and may also be a consequence of chronic exposure to tumor necrosis factor-alpha (TNFalpha). The aim of this study was to examine whether the r...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-003-0374-4
更新日期:2004-11-01 00:00:00