Abstract：
:Patients with rheumatoid arthritis (RA) have bone loss to various degrees at different skeletal sites. The subregional bone mineral density (BMD) of the hand and the correlation of BMD to other regional bone losses, parameters of inflammation or bone resorption was evaluated in 421 patients with RA and controls. RA patients had significantly (P<0.01) lower BMD values in the carpus (0.405+/-0.004 g/cm2), metacarpal joint II (0.318+/-0.036 g/cm2) and metacarpal joint III (0.326+/-0.022 g/cm2) compared to controls. There was no difference in bone density at the lumbar spine or hip. Significant (P<0.001) correlations were found between BMD total of the hand, its subregions, the forearm and hip. Parameters of inflammation correlated significantly (P<0.001) with pyridinolines (r=0.378), desoxypyridinolines (r=0.183), forearm (r=-10, P<0.05), MCP II (r=-0.190, P<0.001), MCP III (r=0.204, P<0.001) and carpus (r=0.191, P<0.001).
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Franck H,Gottwalt Jdoi
10.1007/s00296-008-0638-0subject
Has Abstractpub_date
2008-11-01 00:00:00pages
47-51issue
1eissn
0172-8172issn
1437-160Xjournal_volume
29pub_type
杂志文章abstract：:Recent studies indicate that high-mobility group box protein 1 (HMGB1) contributes to the pathogenesis of diverse autoimmune disorders. It induces the production of interferon-alpha (IFN-alpha) and tumor necrosis factor alpha (TNF-alpha) in vitro. In the present study, plasma HMGB1, TNF-alpha, and IFN-alpha were deter...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1636-6
更新日期：2012-02-01 00:00:00
abstract：:A 42-year-old woman presented with a 3-week history of left knee pain and swelling. She had suffered dermatitis herpetiformis for 12 years, proved by skin biopsy. She had never been on gluten-free diet. Knee pain increased with motion and her gait was antalgic. On admission, she was mainly dependent on wheelchair due ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1670-4
更新日期：2011-05-01 00:00:00
abstract：:The purpose of this study was to determine the association of fibromyalgia (FM) with temporomandibular disorder (TMD) and masticatory myofascial pain (MMP). Thirty-one consecutive women diagnosed as having FM according to American College of Rheumatology criteria and 21 consecutive women diagnosed as having TMD were i...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-006-0251-z
更新日期：2007-04-01 00:00:00
abstract：:The aims of this study were to assess the health-related quality of life (HRQoL) in patients with self-reported rheumatic diseases (RD), to classify self-reported rheumatic patients in groups according to their health state and to explore the associations between health status and sociodemographic variables. Data came...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-016-3517-0
更新日期：2016-09-01 00:00:00
abstract：:Uveitis is an important component of many rheumatic diseases. The main causes of recurrent uveitis are seronegative spondylarthropathies and Behçet's disease. We describe a rare case of Henoch Schönlein vasculitis (HSV) along with multiple recurrences of acute anterior uveitis. In cases of skin rash and recurrent ante...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-1074-5
更新日期：2010-08-01 00:00:00
abstract：:Macrophagic myofascitis (MMF) is an unusual inflammatory myopathy characterized by muscle infiltration by macrophages and lymphocytes. Here, we describe a case of MMF which is associated with rheumatoid arthritis. A 53-year-old Japanese rheumatoid arthritis (RA) patient presented with focal tenderness of lower extremi...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-1015-3
更新日期：2010-05-01 00:00:00
abstract：:We have examined the way in which products of cultured human blood mononuclear cells activate human articular chondrocytes. Conditioned medium from mononuclear cells enhanced the production of prostaglandin E by cultured human chondrocytes and also stimulated fibrinolytic activity in these cultures. These two effects ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00541204
更新日期：1984-01-01 00:00:00
abstract：:A recent genome-wide association study revealed that there is an association between serum uric acid (SUA) levels and rs2544390, a common variant in low-density lipoprotein-related protein 2 (LRP2/Megalin) gene. Two other variants of LRP2, rs2229268 and rs3755166, are also found to have associations with dyslipidemia ...
journal_title：Rheumatology international
pub_type： 杂志文章,多中心研究
doi：10.1007/s00296-013-2924-8
更新日期：2014-04-01 00:00:00
abstract：:Rheumatoid arthritis is a progressive autoimmune disease characterised by severely swollen and painful joints. To compliment pharmacotherapy, people living with rheumatoid arthritis often turn to dietary interventions such as the Mediterranean diet. The aim of the present systematic review is to discuss the effects of...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-017-3912-1
更新日期：2018-05-01 00:00:00
abstract：:PADI4 that catalyzes the conversion of peptidylarginine to citrulline is associated with rheumatoid arthritis in some populations. The current study investigated the expressions of PADI4 in synovial fluid of RA (n = 73), osteoarthritis (OA, n = 96) and ankylosing spondylitis (AS, n = 32) using ELISA and western blotti...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-0870-2
更新日期：2009-10-01 00:00:00
abstract：:Juvenile idiopathic arthritis (JIA) is the most common diagnosis in children and adolescents with rheumatic disorders. In many children and adolescents, JIA is successfully treated with non-steroidal anti-inflammatory drugs (NSAID) and physiotherapy. However, in a significant number of cases the disease is resistant t...
journal_title：Rheumatology international
pub_type： 杂志文章,实务指引
doi：10.1007/s00296-004-0537-y
更新日期：2005-04-01 00:00:00
abstract：OBJECTIVES:To identify recommendations on the diagnosis and management of rheumatoid arthritis (RA) supported by low recommendation grades, to study the causes of this low grading, and to propose solutions. METHODS:A group of six rheumatologists, with extensive experience in the development of systematic reviews, revi...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-020-04724-z
更新日期：2021-01-01 00:00:00
abstract：:Thrombocytosis is well described in children with Kawasaki disease (KD). We describe six children with KD who had thrombocytopenia at disease onset. This is an unusual finding and has clinical implications in the diagnosis of this condition. ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-0947-y
更新日期：2009-12-01 00:00:00
abstract：:Most infectious agents, such as viruses, bacteria and parasites, can trigger autoimmunity via different mechanisms. The development of an autoimmune disorder after infection tends to occur in genetically susceptible individuals. Some parameters, such as genetic predisposition, feature of the infectious agent and somet...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-012-2451-z
更新日期：2012-11-01 00:00:00
abstract：:Statistical analysis plays a critical role in data interpretation in all fields and particularly so for clinical data where important treatment decisions are made. We provide here an in-depth and illustrative analysis to examine patterns and radiographic scores in an early disease rheumatoid arthritis cohort over a 3-...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-013-2879-9
更新日期：2014-02-01 00:00:00
abstract：:We aimed to investigate the diagnostic significance of high frequency ultrasonography (USG), comparing the findings in USG, bone scintigraphy and clinical stuation. Fifty-one patients who had early symptoms of inflammatory arthritis, but not fulfilling the ACR diagnostic criteria for rheumatoid arthritis (RA) were inc...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-008-0765-7
更新日期：2009-05-01 00:00:00
abstract：:We measured alpha 2-plasmin inhibitor-plasmin complexes (PI-PC) in plasma of patients with systemic lupus erythematosus (SLE) to examine the plasminogen activation in SLE. The plasma PI-PC level in 23 patients with SLE was significantly higher than that in 18 normal subjects (P less than 0.001) and the SLE patients wi...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00270984
更新日期：1989-01-01 00:00:00
abstract：:3-Aminobenzamide is an inhibitor of poly-(ADP-ribosyl)ation. In concentrations from 3 to 10 mM it reduced the collagenase activity in culture supernatants of interleukin-1 beta-stimulated rabbit synovial fibroblasts. 3-Aminobenzoate, not an inhibiter of poly(ADP-ribosyl)ation, had no effect on collagenase activity at ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00301776
更新日期：1995-01-01 00:00:00
abstract：:Microvascular lesions are a predominant feature in systemic sclerosis (SSc) and seem to play a central pathogenic role. The presence of nailfold capillary abnormalities is useful in diagnosing SSc. Capillaroscopy, however, usually requires special equipment and may be time consuming. Dermatoscope has been presented as...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1532-0
更新日期：2011-12-01 00:00:00
abstract：:The aim of this systematic review was to evaluate the evidence from randomised controlled trials (RCTs) evaluating the effectiveness of interactive digital interventions (IDIs) for physical activity (PA) and health related quality of life (HRQoL) in people with Inflammatory Arthritis [rheumatoid arthritis (RA), juveni...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-018-4010-8
更新日期：2018-09-01 00:00:00
abstract：:A period of 4 weeks (w) has been recommended for rheumatoid arthritis (RA) patients as the interval between intravenous (IV) tocilizumab (TCZ, 8 mg/kg). In a previous paper, we showed the possibility that the interval between successive IV TCZ can be extended from 4 to 6 weeks in more than 60% of patients with low dis...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-018-4149-3
更新日期：2018-12-01 00:00:00
abstract：:Gout results from multifactor interactions between gender, age, genetic and environmental factors. Environmental factors underlying gout and precipitating factors triggering acute attacks might vary in different populations with different lifestyles. In this study, we aimed to collect data regarding the demographic an...
journal_title：Rheumatology international
pub_type： 杂志文章,多中心研究
doi：10.1007/s00296-012-2442-0
更新日期：2013-04-01 00:00:00
abstract：:There are numerous causes of pulmonary cavitary lesions as infection (bacterial, parasitic and invasive fungal), Wegener granulomatosis (WG) and other vasculitis, sarcoidosis, malignancy, septic thromboembolism, airways disease (cystic bronchiectasis and bullae), pneumatoceles and traumatic parenchymal laceration. Her...
journal_title：Rheumatology international
pub_type： 信件
doi：10.1007/s00296-012-2424-2
更新日期：2013-08-01 00:00:00
abstract：:The aim of the study was to assess the possible association between type II collagen turnover seromarkers and disease profile in patients with axial spondyloarthritis (SpA) and psoriatic arthritis (PsA). Outpatients with axial SpA (n = 110) or PsA (n = 101) underwent clinical examination including disease activity mea...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-015-3397-8
更新日期：2016-04-01 00:00:00
abstract：:Psychiatric manifestations are common in systemic lupus erythematosus (SLE) and often represent a challenging diagnostic and therapeutic problem, mainly because the uncertainties of the pathogenic mechanisms. We report a case of acute psychosis occurring in a female with SLE due to the stress of having a severe diseas...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-007-0479-2
更新日期：2008-02-01 00:00:00
abstract：:The Juvenile Arthritis Multidimensional Assessment Report (JAMAR) is a new parent/patient reported outcome measure that enables a thorough assessment of the disease status in children with juvenile idiopathic arthritis (JIA). We report the results of the cross-cultural adaptation and validation of the parent and patie...
journal_title：Rheumatology international
pub_type： 杂志文章,多中心研究
doi：10.1007/s00296-018-3980-x
更新日期：2018-04-01 00:00:00
abstract：:Individual differences in adjustment during a disease's course determine psychological response and outcome. This study aimed to investigate prospectively whether coping with health stressors and self-sacrificing defense style could predict psychological adjustment and health-related quality of life (HRQoL) in patient...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-014-3134-8
更新日期：2015-04-01 00:00:00
abstract：:The current study was to investigate the quantity and quality of researches in the field of ankylosing spondylitis, and to reveal the characteristics of worldwide productivity on this disease. This was a bibliometric study on ankylosing spondylitis using Web of Science. The numbers of papers, citations, research outpu...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-019-04308-6
更新日期：2019-06-01 00:00:00
abstract：:A total of 300 consecutive patients referred to a tertiary-care center and fulfilling the American Rheumatism Association criteria for definite-classical rheumatoid arthritis, (with a mean disease-duration of 10.3 +/- 9 years) were studied by structured interview and medical record review. The type of onset (rapid or ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00270365
更新日期：1987-01-01 00:00:00
abstract：:Alkoptunuria is an inherited autosomal recessive metabolic disorder which is caused by the lack of homogentisic acid-oxidase enzyme. It is associated with various systemic abnormalities and related to the deposition of homogentisic acid pigment in connective tissues. These pigmentary changes are termed "ochronosis". W...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-004-0538-x
更新日期：2005-08-01 00:00:00
