Abstract:
:Gout results from multifactor interactions between gender, age, genetic and environmental factors. Environmental factors underlying gout and precipitating factors triggering acute attacks might vary in different populations with different lifestyles. In this study, we aimed to collect data regarding the demographic and clinical features, comorbid factors, and precipitating factors associated with the initiation of acute attacks in gout patients in Turkey. A total of 312 patients were included in this study (mean age, 58.8 ± 13.8 years; female/male ratio, 55/257). The demographic features, alcohol intake, clinical and laboratory features, and comorbid conditions including obesity, diabetes mellitus, hyperlipidemia, hypertension, and coronary heart disease were noted in a standard questionnaire. Precipitating factors initiating acute attacks (if any) were also noted. The patients were divided into 4 groups according to the region of location as central Anatolian region, southeast Anatolian region, Aegean region, and Trakya region. Our results were compared according to the gender and the location of the patients. The mean age at the start of the symptoms was 10 years higher in women (60.4 ± 14.8 and 50.6 ± 13.5 years in women and men, respectively, p < 0.001).Obesity was present in 40.1 %, diabetes mellitus in 17.9 %, hyperlipidemia in 30.1 %, hypertension in 53.5 %, coronary artery disease in 17 %, and nephrolithiasis in 21.8 % of patients. Precipitating factors triggering gout flares were as follows: diet (high consumption of meat or fish) in 46.5 %, alcohol consumption in 15.7 %, diuretics in 8.3 %, diet or diuretics in 5.1 %, diet or alcohol in 4.5 %, diet or alcohol or diuretics in 1.6 %, others in 4.2 %, and none in 14.1 %. The presence of diabetes and diuretic use was more common among women. Use of diuretics is a more common trigger for gout flares among women. On the other hand, various comorbid conditions, such as obesity and hypertension, and triggers for gout flares may differ between patients living in different geographic regions. In summary, we reported the first data regarding clinical and demographic characteristics of gout in Turkey. The majority of our patients could describe at least one "trigger" that initiated gout flare. Both comorbid conditions and triggers of attack might differ between men and women, and in different geographic areas. Better knowledge of the modifiable risk factors can be useful for the management strategy to optimize long-term patient outcomes in local clinics.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Öztürk MA,Kaya A,Şenel S,Dönmez S,Balkarlı A,Çobankara V,Erhan Ç,Sayarlıoğlu M,Ugan Y,Tunç ŞE,Pehlivan Y,Kısacık B,Tufan A,Onat AM,Tezcan E,Yıldırım Çetin G,Pamuk ONdoi
10.1007/s00296-012-2442-0subject
Has Abstractpub_date
2013-04-01 00:00:00pages
847-52issue
4eissn
0172-8172issn
1437-160Xjournal_volume
33pub_type
杂志文章,多中心研究abstract::The purpose of this study was to determine the association of fibromyalgia (FM) with temporomandibular disorder (TMD) and masticatory myofascial pain (MMP). Thirty-one consecutive women diagnosed as having FM according to American College of Rheumatology criteria and 21 consecutive women diagnosed as having TMD were i...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-006-0251-z
更新日期:2007-04-01 00:00:00
abstract::Echocardiographic examination and 24-h electrocardiographic Holter monitoring were carried out on 35 patients with nodular rheumatoid arthritis (RA) and 35 with non-nodular RA, who were matched with the nodular RA group regarding age, sex and BSA. A further 35 patients with osteoarthrosis and spondyloarthrosis matched...
journal_title:Rheumatology international
pub_type: 临床试验,杂志文章
doi:10.1007/s002960050079
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abstract::Baseline and sequential liver biopsies were performed in ten patients with rheumatoid arthritis (RA) treated with methotrexate (MTX) for more than 4 years. Liver biopsies were performed in all patients before the initiation of MTX therapy and were repeated after reaching a cumulative dose of 1500 mg or more. In four p...
journal_title:Rheumatology international
pub_type: 临床试验,杂志文章
doi:10.1007/BF00246875
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abstract::We investigated the overall frequency of anti-phospholipid syndrome (APS) occurrence in Korean patients with consecutively detected anti-phospholipid antibodies with an interval of 12 weeks (persistent aPLs). We retrospectively reviewed the results of blood tests of aPLs in 14,889 patients in whom aPL tests were perfo...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-019-04318-4
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVE:The aim was to evaluate the efficacy and safety of multiple infusions with achimeric, anti-tumor necrosis factor (TNF)alpha monoclonal antibody (infliximab) in patients with psoriatic arthritis (PsA) and psoriasis vulgaris. METHODS:Over 22 weeks, nine patients with both active psoriasis and PsA received five...
journal_title:Rheumatology international
pub_type: 临床试验,杂志文章
doi:10.1007/s00296-002-0246-3
更新日期:2002-11-01 00:00:00
abstract::Systemic sclerosis (SSc) is a generalized disorder characterized by fibrosis and vascular obliteration in the skin, lung, gastrointestinal tract, and kidney. One of its two subsets is a stable, limited cutaneous group (lSSc). Pulmonary involvement in scleroderma is common, and several types of pulmonary disorders are ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-002-0230-y
更新日期:2002-09-01 00:00:00
abstract::The mononuclear phagocyte infiltrate which occupies the gout tophus has been compared with that of the subcutaneous rheumatoid nodule. In the gout tophus, macrophage migration appears to be at a relatively low level and effectively terminates once these cells have been recruited into the corona. In the nodule the evid...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00541376
更新日期:1987-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to analyze and compare the demographic and clinical features and prognosis of patients with different systemic necrotizing vasculitides (SNV) in Turkey. PATIENTS AND METHODS:Twenty-three patients with Wegener's granulomatosis (WG), 15 with polyarteritis nodosa (PAN), and two with Ch...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-004-0499-0
更新日期:2005-11-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00390264
更新日期:1994-01-01 00:00:00
abstract::Familial Mediterranean fever (FMF) is a self-limited disease characterized by fever and polyserositis attacks. Arthritis caused by synovitis is either in acute monoarthritis or chronic mono-oligoarthritis form, usually affecting the lower extremities. Another potential but rare form of involvement is spondyloarthropat...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0616-6
更新日期:2008-11-01 00:00:00
abstract::Diabetic muscular infarct (DMI) is a rare condition, which begins with acute onset of extremity pain and swelling. Patients usually have long-standing disease and poorly controlled diabetes mellitus (DM). Thigh muscle group is the most commonly involved side, while lower leg involvement is rare. We represent herein a ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1759-9
更新日期:2012-02-01 00:00:00
abstract::The Fc receptor-like (FCRL) molecules have recently been shown to contribute to the pathogenesis of certain autoimmune disorders. In this study, we investigated the expression levels of FCRL1, 2 and 4 in blood mononuclear cells from rheumatoid arthritis patients using real-time PCR. The mRNA of these molecules was det...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-016-3495-2
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:The prevalence of dermatophytic infections in rheumatoid arthritis is unknown. This study investigated the prevalence of dermatophytosis in patients with rheumatoid arthritis and the relationship between sulfasalazine, low-dose methotrexate and steroid therapy. METHODS:We examined 53 consecutive patients wit...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-002-0238-3
更新日期:2003-01-01 00:00:00
abstract::Plasma fibronectin (FN) was measured in 17 patients with essential mixed cryoglobulinaemia (EMC) and in 17 normal subjects by single radial immunodiffusion (RID) and enzyme-linked immunosorbent assay (ELISA). In 9 patients the presence of FN in the cryoprecipitates was also assessed by immunoblotting. In the EMC group...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00541379
更新日期:1987-01-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-011-2076-7
更新日期:2012-10-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-1013-5
更新日期:2010-05-01 00:00:00
abstract::To evaluate serum levels of IL6 in patients with Kawasaki disease and compare it with CRP, and to assess the role of these biomarkers in predicting coronary changes and resistance to the first-line therapy of this disease in a subset of Indian population. A single centre prospective observational study was conducted a...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-019-04375-9
更新日期:2019-10-01 00:00:00
abstract::Rheumatology has its roots in ancient Greece. Hippocrates and other prominent Greek (Hellenes) physicians in ancient times, Hellenistic, Roman, and Byzantine period were acute observers of disease course and of patients and were able to define many disorders. They wrote books on various aspects of medicine and these w...
journal_title:Rheumatology international
pub_type: 历史文章,杂志文章,评审
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更新日期:2019-06-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
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journal_title:Rheumatology international
pub_type: 信件
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pub_type: 杂志文章,多中心研究
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journal_title:Rheumatology international
pub_type: 杂志文章,评审
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1614-z
更新日期:2011-07-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-007-0479-2
更新日期:2008-02-01 00:00:00
abstract::A 51-year-old man shepherd presented with mild pain and swelling of the right posterior aspect of his right elbow. In ultrasonography, the affected bursal space had swelling and effusion. Moreover, the aspiration of the affected bursa revealed an inflammatory profile. Brucella melitensis was detected in aspirated flui...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-019-04414-5
更新日期:2019-12-01 00:00:00
abstract::Acupuncture has been used to treat various clinical diseases in Eastern medicine. To investigate the analgesic effect of electroacupuncture (EA) pretreatment on carrageenan-induced inflammatory pain, we studied on the effect of EA parameters on an animal model of acute arthritic pain. Pretreatment with 1 mA, 10 Hz EA ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1364-y
更新日期:2011-06-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0749-7
更新日期:2009-04-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/pl00006853
更新日期:2000-01-01 00:00:00
abstract::Systemic lupus erythematosus (SLE) is a severe complex rheumatic disease, but good estimate of its prevalence and risk factors is lacking in China. The aim of the study was to explore the prevalence of SLE and risk factors in rural areas of Anhui Province of China. Eleven counties were randomly selected in Anhui Provi...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-013-2902-1
更新日期:2014-03-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-006-0188-2
更新日期:2006-12-01 00:00:00