Abstract:
:Secondary amyloidosis is a well-known complication of certain familial Mediterranean fever (FMF). We presented three Turkish patients with FMF and biopsy proven amyloidosis. These patients were treated with colchicine 1.5 mg/day. They have experienced five to six peritonitis attacks with fever within 1 year. On admission, the laboratory test results were as follows: serum creatinine 2.3, 0.6, and 0.5 mg/dl; albumin 4.2, 1.9, and 1.8 g/dl; and urinary protein excretion 4, 15, and 10 g/day, respectively. All the patients were started azathioprine (AZA) 100 mg/day and attacks were completely stopped. Laboratory findings were as follows after 1 year of AZA treatment: serum creatinine 1, 0.8, and 0.6 mg/dl; albumin 4.3, 3, and 3.5 g/dl; and urinary protein excretion 3, 8, and 1.5 g/day, respectively. Treatment with azathioprine in addition to colchicine could ameliorate the nephrotic syndrome and control the attacks very effectively in these cases.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Sayarlioglu H,Erkoc R,Sayarlioglu M,Dogan E,Soyoral Ydoi
10.1007/s00296-006-0188-2subject
Has Abstractpub_date
2006-12-01 00:00:00pages
197-9issue
2eissn
0172-8172issn
1437-160Xjournal_volume
27pub_type
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