The effect of various disease-modifying anti-rheumatic drugs on the suppressive function of CD4⁺CD25⁺ regulatory T cells.

abstract：:This study evaluates prospectively whether baseline scores [Health Assessment Questionnaire (HAQ) and SF-36] can predict clinical and radiographic evolution in a cohort of early rheumatoid arthritis (RA) during a 3-year follow-up. Forty consecutive early RA patients were followed for 3 years, while receiving standardi...

journal_title：Rheumatology international

authors： da Mota LM,Dos Santos Neto LL,Oliveira AC,Pereira IA,Burlingame RW,Ménard HA,Laurindo IM

更新日期：2012-12-01 00:00:00

abstract：:The aim of the study is to investigate the levels of serum interleukin-35 (IL-35) before and after treatment and its relationship with clinical parameters as well as the frequency of different subsets of CD4+ T cells in patients with systemic sclerosis (SSc) to explore the role of IL-35 in the pathogenesis of SSc. The...

journal_title：Rheumatology international

authors： Tang J,Lei L,Pan J,Zhao C,Wen J

更新日期：2018-08-01 00:00:00

abstract：:Cutaneous leukocytoclastic vasculitis (CLV) is a small-vessel vasculitis localized to the skin. Many possible causes exist for this pathological condition, including drugs, infection, collagen vascular disease, and malignancy. However, Mycobacterium tuberculosis is rarely reported to be associated with CLV. Here, we r...

journal_title：Rheumatology international

authors： Kim HM,Park YB,Maeng HY,Lee SK

更新日期：2006-10-01 00:00:00

abstract：:The American Rheumatism Association (ARA) clinical criteria have been tested in systemic lupus erythematosus (SLE), progressive systemic sclerosis, polyarteritis nodosa and polymyositis/dermatomyositis. Hospital admissions from a defined population over the same period were studied. Increased weighting of the scores f...

journal_title：Rheumatology international

authors： Tan PL,Borman GB,Wigley RD

更新日期：1981-01-01 00:00:00

abstract：:The capillaroscopic pattern in paraneoplastic Raynaud's phenomenon (RP) has not been investigated systematically and is not well-defined. Here, we present three case reports of patients with paraneoplastic rheumatic conditions, manifested with severe secondary RP with emphasis upon capillaroscopic findings. The first ...

journal_title：Rheumatology international

authors： Lambova S,Müller-Ladner U

更新日期：2013-06-01 00:00:00

abstract：:Thrombotic microangiopathy (TMA)/thrombotic thrombocytopenic purpura (TTP) is a rare but potentially lethal condition requiring rapid recognition, diagnosis, and initiation of therapy. We experienced a case of a 61-year-old woman with primary Sjögren's syndrome (pSS) complicated with severe renal TMA/TTP following IgM...

journal_title：Rheumatology international

authors： Koga T,Yamasaki S,Nakamura H,Kawakami A,Furusu A,Taguchi T,Eguchi K

更新日期：2013-01-01 00:00:00

abstract：:Plasma fibronectin (FN) was measured in 17 patients with essential mixed cryoglobulinaemia (EMC) and in 17 normal subjects by single radial immunodiffusion (RID) and enzyme-linked immunosorbent assay (ELISA). In 9 patients the presence of FN in the cryoprecipitates was also assessed by immunoblotting. In the EMC group...

journal_title：Rheumatology international

authors： Toschi V,Renoldi P,Motta A,Cimminiello C,Arpaia G,Fiorini GF

更新日期：1987-01-01 00:00:00

abstract：:To define the relationship between serum anti-cyclic citrullinated peptide antibodies (anti-CCP) and disease activity, and to construct a new disease activity index by using anti-CCP in rheumatoid arthritis (RA). One hundred and five RA patients were included. Disease activity based on DAS28-ESR and serum anti-CCP was...

journal_title：Rheumatology international

authors： Esalatmanesh K,Jamali R,Jamali A,Jamali B,Nikbakht M

更新日期：2012-12-01 00:00:00

abstract：:Recent studies indicate that high-mobility group box protein 1 (HMGB1) contributes to the pathogenesis of diverse autoimmune disorders. It induces the production of interferon-alpha (IFN-alpha) and tumor necrosis factor alpha (TNF-alpha) in vitro. In the present study, plasma HMGB1, TNF-alpha, and IFN-alpha were deter...

journal_title：Rheumatology international

authors： Ma CY,Jiao YL,Zhang J,Yang QR,Zhang ZF,Shen YJ,Chen ZJ,Zhao YR

更新日期：2012-02-01 00:00:00

abstract：:A 51-year-old man shepherd presented with mild pain and swelling of the right posterior aspect of his right elbow. In ultrasonography, the affected bursal space had swelling and effusion. Moreover, the aspiration of the affected bursa revealed an inflammatory profile. Brucella melitensis was detected in aspirated flui...

journal_title：Rheumatology international

authors： Esmaeilnejad-Ganji SM,Roushan MRH,Ebrahimpour S,Babazadeh A

更新日期：2019-12-01 00:00:00

abstract：:Reported here is a 19-year-old female patient with familial Mediterranean fever who was seen for altered mental status and seizures. She was eventually diagnosed to have posterior reversible leukoencephalopathy syndrome. Although a variety of conditions have been reported in association with this syndrome, to our best...

journal_title：Rheumatology international

authors： Ulaşlı AM,Kutlu G,Kocatürk Ö,Özçakar L

更新日期：2012-06-01 00:00:00

abstract：:Serum deoxyribonuclease I (DNase I) activity in systemic lupus erythematosus (SLE) patients was shown to be lower than that of healthy laboratory personnel, rheumatoid arthritis, and scleroderma patients (P less than 0.001). The decrease in DNase I activity in SLE sera was not due to the effect of various autoantibodi...

journal_title：Rheumatology international

authors： Chitrabamrung S,Rubin RL,Tan EM

更新日期：1981-01-01 00:00:00

abstract：:The objective of this study was to search for proteomic patterns distinguishing patients with rheumatoid arthritis (RA) from healthy controls, biomarker candidates specific for early RA, and proteins reflecting disease activity, by profiling of serum proteins using magnetic bead-based (MB) separation and matrix-assist...

journal_title：Rheumatology international

authors： Long L,Li R,Li Y,Hu C,Li Z

更新日期：2011-08-01 00:00:00

abstract：:The association of familial Mediterranean fever (FMF) and polyarteritis nodosa (PAN) has been well established. These patients have been reported to have an overall better prognosis than other PAN patients. Herein we report a patient with FMF and PAN who died of sepsis following a severe course of recurrent bleeding e...

journal_title：Rheumatology international

authors： Akar S,Goktay Y,Akinci B,Tekis D,Biberoglu K,Birlik M,Onen F,Tunca M,Akkoc N

更新日期：2005-01-01 00:00:00

abstract：:Axial spondyloarthritis (axSpA) is a chronic inflammatory rheumatic disease affecting predominantly sacroiliac joints and axial skeleton. axSpA progression being irregular and hardly predictable, identifying functional decline is particularly important in patient with axSpA to allow delivery of timely and targeted int...

journal_title：Rheumatology international

authors： Soulard J,Vuillerme N,Gaudin P,Grange L,Baillet A,Cracowski JL,Juvin R,Vaillant J

更新日期：2019-10-01 00:00:00

abstract：:Sleep disturbances and problems are increased in ankylosing spondylitis (AS). But much is not known in a quantitative way about sleep problems and effect of treatments on AS. This study is aimed first, to investigate sleep disturbances in AS and secondly, to evaluate the effects of anti-TNF treatment on SD in AS. One ...

journal_title：Rheumatology international

authors： Karadağ O,Nakas D,Kalyoncu U,Akdoğan A,Kiraz S,Ertenli I

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Axillary lymph nodes (ALNs) are often seen on chest computed tomography (CT) in rheumatoid arthritis (RA) patients. Early reports described lymphadenopathy as one of the systemic manifestations rather than regional lymphadenopathy secondary to drainage from the affected joints. Subsequently, the importance o...

journal_title：Rheumatology international

authors： Hasegawa M,Sakai F,Konda N,Okabayashi A,Katsura H,Seto Y

更新日期：2018-06-01 00:00:00

abstract：:The mononuclear phagocyte infiltrate which occupies the gout tophus has been compared with that of the subcutaneous rheumatoid nodule. In the gout tophus, macrophage migration appears to be at a relatively low level and effectively terminates once these cells have been recruited into the corona. In the nodule the evid...

journal_title：Rheumatology international

authors： Palmer DG,Hogg N,Denholm I,Allen CA,Highton J,Hessian PA

更新日期：1987-01-01 00:00:00

abstract：:Healthy human sexuality is integral to a well-lived life. Recent studies reported that sexual problems were common in patients with ankylosing spondylitis (AS) in relation to the consequences of the illness such as pain, stiffness of the spine and depression. Twenty-three female patients with AS and 27 healthy female ...

journal_title：Rheumatology international

authors： Demir SE,Rezvani A,Ok S

更新日期：2013-01-01 00:00:00

abstract：:Behçet's syndrome (BS) is a chronic (auto)-inflammatory disorder characterized by different clusters of symptoms, including mucocutaneous and ocular involvements. Interleukin-1 inhibitors anakinra (ANA), canakinumab (CAN), and gevokizumab (GEV) represent a promising therapeutic alternative in BS. To date, evidence on ...

journal_title：Rheumatology international

authors： Bettiol A,Silvestri E,Di Scala G,Amedei A,Becatti M,Fiorillo C,Lopalco G,Salvarani C,Cantarini L,Soriano A,Emmi G

更新日期：2019-06-01 00:00:00

abstract：:A total of 95 patients suffering from active rheumatoid arthritis were included in this double-blind, placebo-controlled study of the immunomodulator OM-8980. Treatment was one capsule daily of OM-8980 or placebo for 6 months. A significant improvement was observed in the OM-8980 group in comparison with the placebo g...

journal_title：Rheumatology international

authors： Hauzeur JP,Appelboom T

更新日期：1989-01-01 00:00:00

abstract：:MicroRNAs (miRNAs) are noncoding RNA molecules of 21-24 nt that regulate the expression of target genes in a post-transcriptional manner. Evidence indicates that miRNAs play essential roles in embryogenesis, cell differentiation, and pathogenesis of human diseases. This study describes a comparison between the miRNA p...

journal_title：Rheumatology international

authors： Dai Y,Sui W,Lan H,Yan Q,Huang H,Huang Y

更新日期：2009-05-01 00:00:00

abstract：:The current clinical and laboratory parameters of Takayasu arteritis (TA) are insufficient for proper assessment of disease activity. The aims of this study were to investigate the markers of endothelial injury and repair, including circulating endothelial cell (CEC), circulating endothelial progenitor cell (CEPC) and...

journal_title：Rheumatology international

authors： Dogan S,Piskin O,Solmaz D,Akar S,Gulcu A,Yuksel F,Cakır V,Sari I,Akkoc N,Onen F

更新日期：2014-08-01 00:00:00

abstract：:This study aims to elucidate plasma oxidant/antioxidant status in patients with rheumatoid arthritis (RA). Fasting blood samples were obtained from 24 patients with RA and 20 control subjects. Antioxidant potential (AOP) value, nonenzymatic superoxide radical scavenger activity (NSSA), and malondialdehyde (MDA) levels...

journal_title：Rheumatology international

authors： Oztürk HS,Cimen MY,Cimen OB,Kaçmaz M,Durak I

更新日期：1999-01-01 00:00:00

abstract：:P wave dispersion (PWD) is a sign for the prediction of atrial fibrillation (AF). The aim of this study was to assess P wave dispersion and its relation with clinical and echocardiographic parameters in patients with rheumatoid arthritis (RA). Thirty RA patients (mean age 49 +/- 10 years) and 27 healthy controls (mean...

journal_title：Rheumatology international

authors： Guler H,Seyfeli E,Sahin G,Duru M,Akgul F,Saglam H,Yalcin F

更新日期：2007-07-01 00:00:00

abstract：:Both self-reported and physical performance tests are used as outcome measures in knee osteoarthritis (OA). The aim of this study is to investigate the relationship between Knee Injury and Osteoarthritis Outcome Score (KOOS) and Timed Up and Go (TUG) test in the patients with symptomatic knee OA. Eighty-nine patients ...

journal_title：Rheumatology international

authors： Sabirli F,Paker N,Bugdayci D

更新日期：2013-10-01 00:00:00

abstract：:Osteoarthritis (OA) is a multifactorial degenerative pathology, whose progression is exacerbated by pro-inflammatory cytokines signaling. Among the changes triggered in chondrocytes during inflammation, modified expression of tiny epigenetic regulators as microRNAs was shown having deleterious implications for articul...

journal_title：Rheumatology international

authors： Santini P,Politi L,Vedova PD,Scandurra R,Scotto d'Abusco A

更新日期：2014-05-01 00:00:00

abstract：:Balneotherapeutic applications to treat rheumatic diseases have a long-term tradition and are based on established scientific principles, and the majority of rheumatic diseases most frequently include balneotherapy. However, as other therapeutic strategies, balneological interventions require scientific proof of their...

journal_title：Rheumatology international

authors： Lange U,Müller-Ladner U,Schmidt KL

更新日期：2006-04-01 00:00:00

abstract：:We characterized the anemia in monkey collagen-induced arthritis (CIA) to evaluate whether this model is useful to analyze the basis of an anemia of inflammatory diseases. Cynomolgus monkey was immunized with bovine type II collagen on days 0 and 21. Blood samples were collected regularly and hematological parameters,...

journal_title：Rheumatology international

authors： Uchiyama Y,Koike N,Mihara M

更新日期：2008-07-01 00:00:00

abstract：:Fluoride excess primarily effects dental and skeletal tissues. leading to a condition known as endemic fluorosis. The radiological and clinical features of endemic fluorosis vary in different parts of the world. The aim of this study was to investigate the clinical and radiological features of endemic fluorosis in Tur...

journal_title：Rheumatology international

authors： Savas S,Cetin M,Akdoğan M,Heybeli N

更新日期：2001-09-01 00:00:00