Incidence of infection other than tuberculosis in patients with autoimmune rheumatic diseases treated with bDMARDs: a real-time clinical experience from India.

abstract：AIM:The aim of this study was to assess the efficacy of long-term azathioprine and steroids for treatment of severe nephritis in children with Henoch-Schönlein purpura (HSP). METHODS:Analysis of case records of children with HSP followed up for a mean duration of 4.7 years (range 6 months-6.5 years) was performed. All...

journal_title：Rheumatology international

authors： Singh S,Devidayal,Kumar L,Joshi K,Minz RW,Datta U

更新日期：2002-08-01 00:00:00

abstract：:In rheumatoid arthritis (RA), a disease characterized by bone loss, increased levels of serotonin have been reported. Recent studies have demonstrated a role for circulating serotonin as a regulator of osteoblastogenesis, inhibiting bone formation. Thus, we measured serum serotonin levels (SSL) in a Portuguese sample ...

journal_title：Rheumatology international

authors： Bernardes M,Vieira T,Lucas R,Pereira J,Costa L,Simões-Ventura F,Martins MJ

更新日期：2017-11-01 00:00:00

abstract：:Several studies have shown a negative association between smoking and primary Sjögren's syndrome (pSS), and smoking may interfere with the immune response. The purpose of this study was to investigate if smoking affects disease activity and disease phenotype in pSS. In this cross-sectional study, consecutive pSS patie...

journal_title：Rheumatology international

authors： Olsson P,Bodewes ILA,Nilsson AM,Turesson C,Jacobsson LTH,Theander E,Versnel MA,Mandl T

更新日期：2019-09-01 00:00:00

abstract：:To evaluate the correlation between measurements of antinuclear antibodies serum levels by enzyme immunoassay (ANA-EIA), and the degree of systemic lupus erythematosus disease activity. To retest the performance of the test compared to measurement of antinuclear antibodies by immunofluorescence (ANA-IIF). Eighty-five ...

journal_title：Rheumatology international

authors： Paz E,Adawi M,Lavi I,Mussel Y,Mader R

更新日期：2007-08-01 00:00:00

abstract：:The aim of this study was to identify the possible determinants of impaired health-related quality of life (HRQOL) in Egyptian children and adolescents with juvenile idiopathic arthritis (JIA). Fifty-eight consecutive patients of JIA aged from 8 to 18 years underwent assessment of socio-economic and demographic charac...

journal_title：Rheumatology international

authors： Abdul-Sattar AB,Elewa EA,El-Shahawy Eel-D,Waly EH

更新日期：2014-08-01 00:00:00

abstract：:We studied the depletion and repopulation of synovial lining cells in mice. A single intra-articular injection of liposomes encapsulating the drug dichloromethylene diphosphonate (CL2MDP) in the mouse knee joint caused selective elimination of synovial lining cells. Depletion of cells occurred within a few days as evi...

journal_title：Rheumatology international

authors： van Lent PL,van den Bersselaar L,van den Hoek AE,van de Ende M,Dijkstra CD,van Rooijen N,van de Putte LB,van den Berg WB

更新日期：1993-01-01 00:00:00

abstract：:This study was designed to determine the effects of the osteoprotegerin (OPG) on the mRNA expression of carbonic anhydrase II (CAII) and the receptor activator of NF-κB (RANK) in mouse osteoclast-like cells. Marrow cells were harvested from femora and tibiae of mouse and cultured in 6-well chamber slides. After 1 day ...

journal_title：Rheumatology international

authors： Chen J,He JQ,Zhen SY,Huang LQ

更新日期：2012-12-01 00:00:00

abstract：:Necrotic areas of rheumatoid nodules were investigated electron microscopically. PMNs in different stages of disintegration were present in all cases. Granular material, sometimes in a fiberlike orientation, and small fibrils without periodicity were detected between the collagenous fibers. It is assumed that granular...

journal_title：Rheumatology international

authors： Mohr W,Köhler G,Wessinghage D

更新日期：1981-01-01 00:00:00

abstract：:Synovial fluids of patients suffering from rheumatoid arthritis contain elevated levels of granulocyte (PMN) elastase in complex with alpha 1-proteinase inhibitor (alpha 1-PI), whereas free-elastase activity is usually not detectable. This absence of free enzymatic activity in joint effusions has cast some doubt on th...

journal_title：Rheumatology international

authors： Burkhardt H,Kasten M,Rauls S,Rehkopf E

更新日期：1987-01-01 00:00:00

abstract：:Recent studies indicate that high-mobility group box protein 1 (HMGB1) contributes to the pathogenesis of diverse autoimmune disorders. It induces the production of interferon-alpha (IFN-alpha) and tumor necrosis factor alpha (TNF-alpha) in vitro. In the present study, plasma HMGB1, TNF-alpha, and IFN-alpha were deter...

journal_title：Rheumatology international

authors： Ma CY,Jiao YL,Zhang J,Yang QR,Zhang ZF,Shen YJ,Chen ZJ,Zhao YR

更新日期：2012-02-01 00:00:00

abstract：:Rheumatoid arthritis is a systemic autoimmune disease resulting in joint destruction and deformities, but also associated with extraarticular and systemic manifestations. The later devastating conditions, such as the development of rheumatoid vasculitis, are more frequently encountered in seropositive patients and the...

journal_title：Rheumatology international

authors： Skalkou A,Manoli SM,Sachinidis A,Ntouros V,Petidis K,Pagkopoulou E,Vakirlis E,Pyrpasopoulou A,Dimitroulas T

更新日期：2018-01-01 00:00:00

abstract：:Echocardiographic examination and 24-h electrocardiographic Holter monitoring were carried out on 35 patients with nodular rheumatoid arthritis (RA) and 35 with non-nodular RA, who were matched with the nodular RA group regarding age, sex and BSA. A further 35 patients with osteoarthrosis and spondyloarthrosis matched...

journal_title：Rheumatology international

authors： Wisłowska M,Sypuła S,Kowalik I

更新日期：1999-01-01 00:00:00

abstract：:Here we evaluated whether 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) have beneficial effects for collagen-induced arthritis (CIA). DBA/1 mice were immunized with bovine type-II collagen and administered 100 mg/kg of pravastatin interperitoneally. We measured the effects of pravastatin for CIA...

journal_title：Rheumatology international

authors： Yamagata T,Kinoshita K,Nozaki Y,Sugiyama M,Ikoma S,Funauchi M

更新日期：2007-05-01 00:00:00

abstract：:The objective of the study was to evaluate synovial tissue receptor activator of nuclear factor-κβ ligand (RANKL) and osteoprotegerin (OPG) as biomarkers of disease activity, progressive joint damage, and therapeutic response, during cytokine blockade in rheumatoid arthritis (RA). Patients with active RA entered a ran...

journal_title：Rheumatology international

authors： Rooney T,Edwards CK 3rd,Gogarty M,Greenan L,Veale DJ,FitzGerald O,Dayer JM,Bresnihan B

更新日期：2010-11-01 00:00:00

abstract：:This study evaluates prospectively whether baseline scores [Health Assessment Questionnaire (HAQ) and SF-36] can predict clinical and radiographic evolution in a cohort of early rheumatoid arthritis (RA) during a 3-year follow-up. Forty consecutive early RA patients were followed for 3 years, while receiving standardi...

journal_title：Rheumatology international

authors： da Mota LM,Dos Santos Neto LL,Oliveira AC,Pereira IA,Burlingame RW,Ménard HA,Laurindo IM

更新日期：2012-12-01 00:00:00

abstract：:The objective of this study was to evaluate human papillomavirus (HPV) and Chlamydia trachomatis (CT) infections in RA patients pre- and post-TNF blocker. Fifty female RA patients (ACR criteria), who were eligible to anti-TNF therapy [n = 50 at baseline (BL) and n = 45 after 6 months of treatment (6 M)], and 50 age-ma...

journal_title：Rheumatology international

authors： Waisberg MG,Ribeiro AC,Candido WM,Medeiros PB,Matsuzaki CN,Beldi MC,Tacla M,Caiaffa-Filho HH,Bonfa E,Silva CA

更新日期：2015-03-01 00:00:00

abstract：:As has been shown by a number of working groups, primary fibromyalgia syndrome does not represent a single clinical entity. It is possible to distinguish between a subgroup with high pain sensitivity and no associated psychiatric condition, a second and a third subgroup characterized by depression associated with fibr...

journal_title：Rheumatology international

authors： Müller W,Schneider EM,Stratz T

更新日期：2007-09-01 00:00:00

abstract：:Previous studies have demonstrated an increased risk of breast cancer among patients with systemic sclerosis (scleroderma). To describe the clinical characteristics of 21 patients with both systemic sclerosis and breast cancer, and compare their risk factors to female scleroderma patients without breast cancer, in a p...

journal_title：Rheumatology international

authors： Lu TY,Hill CL,Pontifex EK,Roberts-Thomson PJ

更新日期：2008-07-01 00:00:00

abstract：:Thrombocytosis is well described in children with Kawasaki disease (KD). We describe six children with KD who had thrombocytopenia at disease onset. This is an unusual finding and has clinical implications in the diagnosis of this condition. ...

journal_title：Rheumatology international

authors： Singh S,Gupta D,Suri D,Kumar RM,Ahluwalia J,Das R,Varma N

更新日期：2009-12-01 00:00:00

abstract：:Patients with rheumatoid arthritis (RA) have bone loss to various degrees at different skeletal sites. The subregional bone mineral density (BMD) of the hand and the correlation of BMD to other regional bone losses, parameters of inflammation or bone resorption was evaluated in 421 patients with RA and controls. RA pa...

journal_title：Rheumatology international

authors： Franck H,Gottwalt J

更新日期：2008-11-01 00:00:00

abstract：:We report a case of a 39-year-old female with active systemic lupus erythematosus who complained of lethargy and weakness with a moderate renal impairment. Hypercalcemia was confirmed by laboratory examination. Her X-ray revealed significant ectopic calcinosis in subcutaneous tissue of bilateral hands, and Tc-99(m) me...

journal_title：Rheumatology international

authors： Zhao L,Huang L,Zhang X

更新日期：2016-07-01 00:00:00

abstract：:Takayasu arteritis (TA) is a rare autoimmune disease of unknown etiology. Genome-wide association studies (GWAS) have demonstrated association between genetic variants of IL12B and IL6 and TA. Since TA has been reported with ethnic heterogeneity, we sought to investigate whether the single-nucleotide-polymorphisms (SN...

journal_title：Rheumatology international

authors： Wen X,Chen S,Li P,Li J,Wu Z,Li Y,Li L,Yuan H,Tian X,Zhang F,Li Y

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVES:We aimed to assess the clinical significance of Krebs von den Lungen-6 (KL-6) in the diagnosis and severity of interstitial lung disease (ILD) in a French cohort of patients with systemic sclerosis (SSc). METHODS:Serum KL-6 concentrations were measured with chemiluminescent enzyme immunoassay (CLEIA) in 75 ...

journal_title：Rheumatology international

authors： Benyamine A,Heim X,Resseguier N,Bertin D,Gomez C,Ebbo M,Harlé JR,Kaplanski G,Rossi P,Bardin N,Granel B

更新日期：2018-05-01 00:00:00

abstract：:Sjogren's syndrome (SS) is a systemic autoimmune disease characterized by xerophthalmia, xerostomia and extraglandular manifestations. Anemia, leukopenia, thrombocytopenia and lymphoproliferative disorders, including lymphoma are well-known extraglandular, hematological complications of SS. We report here a rare case ...

journal_title：Rheumatology international

authors： Choung BS,Yoo WH

更新日期：2012-05-01 00:00:00

abstract：:Leflunomide is a new immunosuppressive medicine that has been effectively used in the therapy of rheumatoid arthritis and subsequently used with success in animal models and patients with systemic lupus erythematosus (SLE). However, its use has also been associated with significant and serious adverse reactions involv...

journal_title：Rheumatology international

authors： Wu GC,Xu XD,Huang Q,Wu H

更新日期：2013-02-01 00:00:00

abstract：:We have investigated the prevalence of dry mouth among patients with autoimmune diseases other than Sjögren's syndrome. One hundred and forty-four patients, excluding patients with primary Sjögren's syndrome, were enrolled in this study. The volume of saliva secreted was measured with the screening technique for estim...

journal_title：Rheumatology international

authors： Maeshima E,Furukawa K,Maeshima S,Koshiba H,Sakamoto W

更新日期：2013-12-01 00:00:00

abstract：:In a study of synovial fluid from 110 patients with various forms of arthritis, platelets were identified in the synovial fluid of all the 50 rheumatoids, in 18 out of the 25 (72%) with osteoarthritis and in all 35 of those with other forms of inflammatory osteoarthrosis. Identification of platelets by light microscop...

journal_title：Rheumatology international

authors： Farr M,Wainwright A,Salmon M,Hollywell CA,Bacon PA

更新日期：1984-01-01 00:00:00

abstract：:We sought to determine the prevalence of additional connective tissue diseases (CTDs) in patients with idiopathic inflammatory myopathies (IIM), and to study the muscle biopsy patterns in various clinico-serologic subsets of myositis. We undertook a retrospective cohort study of 648 patients with a histological diagno...

journal_title：Rheumatology international

authors： Maundrell A,Proudman S,Limaye V

更新日期：2019-10-01 00:00:00

abstract：:Abnormal manifestations of central nervous system in system lupus erythematosus (SLE) patients are mainly caused by primary neuropsychiatric SLE (NP-SLE). We reported a new onset SLE patient who had secondary neuropsychiatric manifestations caused by Epstein-Barr virus (EBV) encephalitis. Although EBV has an uncertain...

journal_title：Rheumatology international

authors： Hongbo C,Hongzhen M,Lingzhi H,Maosheng X,Mei C

更新日期：2012-08-01 00:00:00

abstract：:The mechanisms of male idiopathic osteoporosis are little known. We evaluated bone mineral loss by dual-energy X-ray absorptiometry and determined its cortical or trabecular nature in a cohort of men with idiopathic osteoporosis with fractures. Thirty-nine men (mean age 60 ± 13 years), with negative investigations for...

journal_title：Rheumatology international

authors： Laroche M

更新日期：2012-10-01 00:00:00