Prevalence of other connective tissue diseases in idiopathic inflammatory myopathies.

abstract：:Accumulating evidence suggests that defects in the function of CD4(+)CD25(+) regulatory T cells (Tregs) are important in immune-mediated diseases such as rheumatoid arthritis. Here, we investigated the effects of various disease-modifying anti-rheumatic drugs (DMARDs) on Treg function. Tregs and CD4(+)CD25(-) effector...

journal_title：Rheumatology international

authors： Oh JS,Kim YG,Lee SG,So MW,Choi SW,Lee CK,Yoo B

更新日期：2013-02-01 00:00:00

abstract：:We measured alpha 2-plasmin inhibitor-plasmin complexes (PI-PC) in plasma of patients with systemic lupus erythematosus (SLE) to examine the plasminogen activation in SLE. The plasma PI-PC level in 23 patients with SLE was significantly higher than that in 18 normal subjects (P less than 0.001) and the SLE patients wi...

journal_title：Rheumatology international

authors： Negoro N,Kanayama Y,Takeda T,Fujisawa M,Okamura M,Inoue T

更新日期：1989-01-01 00:00:00

abstract：:Hand osteoarthritis (OA) is a common degenerative joint disorder leading to substantial pain and disability. The most severe subtype is erosive hand OA characterized by an abrupt onset, local inflammation, subchondral erosions and worse outcomes than non-erosive disease. Biomarkers of hand OA could help to diagnose th...

journal_title：Rheumatology international

authors： Lennerová T,Pavelka K,Šenolt L

更新日期：2018-05-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is a chronic inflammatory disorder leading to disability and reduced quality of life. Effective treatment with biologic DMARDs poses a significant economic burden. The Abatacept versus Adalimumab Comparison in Biologic-Naïve RA Subjects with Background Methotrexate (AMPLE) trial was a head-to...

journal_title：Rheumatology international

authors： Weijers L,Baerwald C,Mennini FS,Rodríguez-Heredia JM,Bergman MJ,Choquette D,Herrmann KH,Attinà G,Nappi C,Merino SJ,Patel C,Mtibaa M,Foo J

更新日期：2017-07-01 00:00:00

abstract：:Systemic sclerosis (SSc) is an autoimmune rheumatic disease characterised by vasculopathy, inflammation and fibrosis in multiple organs and occasionally coexists with rheumatic conditions, such as axial spondyloarthritis (axSpA). The aim of this study was to demonstrate the successful use of tofacitinib in SSc and axi...

journal_title：Rheumatology international

authors： Kyriakou A,Parperis K,Nikiphorou E,Psarelis S

更新日期：2021-01-12 00:00:00

abstract：:Sarcoidosis is a chronic granulomatous inflammation. The clinical spectrum in childhood is heterogeneous. Angiotensin converting enzyme activity is used as a marker for disease activity. Human chitotriosidase is produced in macrophages. In this study, serum chitotriosidase levels were significantly higher in active sa...

journal_title：Rheumatology international

authors： Brunner J,Scholl-Bürgi S,Prelog M,Zimmerhackl LB

更新日期：2007-10-01 00:00:00

abstract：:Acute leukemia is uncommonly seen with rheumatoid arthritis during or following treatment with low-dose methotrexate, a safe and effective treatment for the arthritic condition. We describe here a 68-year-old woman with rheumatoid arthritis who developed acute erythroleukemia during low-dose methotrexate therapy (tota...

journal_title：Rheumatology international

authors： Choi BR,Ahn MJ,Lee WS,Kim TH,Bae SC,Jun JB

更新日期：2005-05-01 00:00:00

abstract：:Although arthroscopic surgery (AS) for knee osteoarthritis has been widely employed, scientific evidence is lacking. The purpose of this study was to investigate temporal changes in synovial fluid levels of biochemical markers associated with cartilage metabolism following AS. Twenty-five knees of 24 patients with med...

journal_title：Rheumatology international

authors： Nakajima A,Nakagawa K,Aoki Y,Sonobe M,Shibata Y,Yamazaki M,Murakami M

更新日期：2013-01-01 00:00:00

abstract：:Proliferation of pannus tissue cells has been investigated under in vitro conditions after labeling of joint tissues with 3H-thymidine. It was demonstrated that there is only a minimal proliferation of chondrocytes as well as of pannus tissue cells. Slight increased proliferation was observed in granulation tissue poo...

journal_title：Rheumatology international

authors： Mohr W,Hummler N,Pelster B,Wessinghage D

更新日期：1986-01-01 00:00:00

abstract：:Previous studies showed a link between systemic lupus erythematosus (SLE) and Epstein-Barr virus (EBV) infection. We sought to determine the features of serologic response to EBV in SLE patients and whether this response differs from those of systemic sclerosis (SSc) and primary antiphospholipid syndrome (PAPS) patien...

journal_title：Rheumatology international

authors： Esen BA,Yılmaz G,Uzun S,Ozdamar M,Aksözek A,Kamalı S,Türkoğlu S,Gül A,Ocal L,Aral O,Inanç M

更新日期：2012-01-01 00:00:00

abstract：:Ultrasonography (US) and power Doppler sonography (PDS) was used to investigate causes of new onset of shoulder pain and sites of shoulder inflammation in 157 shoulders of 99 patients with rheumatoid arthritis (RA). US detected effusion and/or synovitis in 92/157 glenohumeral joints, subdeltoid bursitis in 56/157 shou...

journal_title：Rheumatology international

authors： Stegbauer J,Rump LC,Weiner SM

更新日期：2008-03-01 00:00:00

abstract：:Healthy human sexuality is integral to a well-lived life. Recent studies reported that sexual problems were common in patients with ankylosing spondylitis (AS) in relation to the consequences of the illness such as pain, stiffness of the spine and depression. Twenty-three female patients with AS and 27 healthy female ...

journal_title：Rheumatology international

authors： Demir SE,Rezvani A,Ok S

更新日期：2013-01-01 00:00:00

abstract：:The aim of this study was to investigate musculoskeletal ultrasound (MSUS) as a diagnostic modality in DISH and to explore whether it might help in elucidating its pathogenesis and events that precede the calcification/ossification process. Fifty patients with DISH and 34 patients with osteoarthritis of the lower limb...

journal_title：Rheumatology international

authors： Mader R,Novofastovski I,Iervolino S,Pavlov A,Chervinsky L,Schwartz N,Pappone N

更新日期：2015-03-01 00:00:00

abstract：:There is no agreement among the rheumatology community in how to implement the musculoskeletal ultrasound (MSUS) technique in the Rheumatology Divisions. To test the perceived usefulness of the MSUS, under consensus indications, for referring colleagues for the clinical management of their patients with inflammatory a...

journal_title：Rheumatology international

authors： Acebes C,Harvie JP,Wilson A,Duthie J,Bowen F,Steven M

更新日期：2016-12-01 00:00:00

abstract：:A community-based cohort comprising 150 patients with recent-onset seropositive arthritis or seronegative oligoarthritis or polyarthritis was monitored for 8 years. Of the different rheumatoid factor (RF) tests, the initial positivity in the most sensitive assays (latex slide test and IgM-RF by enzyme immunoassay) was...

journal_title：Rheumatology international

authors： Tuomi T,Aho K,Palosuo T,Kaarela K,von Essen R,Isomäki H,Leirisalo-Repo M,Sarna S

更新日期：1988-01-01 00:00:00

abstract：:Establishing prevention and therapeutic strategies for osteoarthritis (OA) is necessary to minimize functional disability and the impact of the disease on society. The aim of this study was to determine the effects of an exercise therapy protocol on inflammatory markers, perception of pain, and physical performance in...

journal_title：Rheumatology international

authors： Aguiar GC,Do Nascimento MR,De Miranda AS,Rocha NP,Teixeira AL,Scalzo PL

更新日期：2015-03-01 00:00:00

abstract：:The objective of this study was to analyze the clinical characteristics, associated disorders, and the most common sites of stress fractures in rheumatological patients. Over a 3-year period, 35 patients with 44 stress fractures were prospectively recruited from an outpatient rheumatological department (32 postmenopau...

journal_title：Rheumatology international

authors： Peris P

更新日期：2002-06-01 00:00:00

abstract：:We report three patients with rheumatoid arthritis (RA) who were treated with anti-TNF-α agents and who developed drug-induced lupus (DIL). Two of them received etanercept and the remainder adalimumab. We also present the favorable response observed with the withdrawal of the anti-TNF-alpha agents and the introduction...

journal_title：Rheumatology international

authors： Diaz JC,Vallejo S,Cañas CA

更新日期：2012-10-01 00:00:00

abstract：:TNF-α is one of the key proinflammatory cytokines in pathogenesis of rheumatoid arthritis (RA). TNF-α was also found to enhance synthesis of leptin. Leptin is mainly adipocyte-derived hormone controlling appetite and energy expenditure. It acts through inhibition of neuropeptide Y secretion. It is possible that TNF-α-...

journal_title：Rheumatology international

authors： Kopec-Medrek M,Kotulska A,Widuchowska M,Adamczak M,Więcek A,Kucharz EJ

更新日期：2012-11-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is a chronic systemic disorder characterized by the development through angiogenesis, which is dependent on endothelial cell activation, migration and proliferation and CCL21 plays an important role in this pathology. Currently, CCL21 gene polymorphism studies on rheumatoid arthritis are scar...

journal_title：Rheumatology international

authors： Li G,Zhao J,Li B,Ma J,Zhao Q,Wang X,Lv Z,Li K,Du Z,Ma X,Liu J

更新日期：2017-10-01 00:00:00

abstract：:To investigate the efficacy of etanercept and MTX (methotrexate) combination therapy in Chinese patients with ankylosing spondylitis hip joint lesion, the possible courses and maintenance protocol, altogether 97 ankylosing spondylitis patients fulfilling the modified New York criteria with hip joint lesion were enroll...

journal_title：Rheumatology international

authors： Lian F,Yang X,Liang L,Xu H,Zhan Z,Qiu Q,Ye Y

更新日期：2012-06-01 00:00:00

abstract：:To study the combined effect of both genetic and environmental factors in the age of rheumatoid arthritis onset. Patients (n = 507). Shared epitope characterization was performed using Lifecodes HLA-SSO. Genotyping of protein tyrosine phosphatase non-receptor 22 (PTPN22) rs2476601 and signal transducers and activators...

journal_title：Rheumatology international

authors： Rodríguez-Rodríguez L,Lamas JR,Varadé J,Tornero-Esteban P,Abasolo L,de la Concha EG,Jover JA,Urcelay E,Fernández-Gutiérrez B

更新日期：2012-10-01 00:00:00

abstract：:To establish whether a cadaver model can serve as an effective surrogate for the detection of tendon damage characteristic of rheumatoid arthritis (RA). In addition, we evaluated intraobserver and interobserver agreement in the grading of RA-like tendon tears shown by US, as well as the concordance between the US find...

journal_title：Rheumatology international

authors： Janta I,Morán J,Naredo E,Nieto JC,Uson J,Möller I,Bong D,Bruyn GA,D Agostino MA,Filippucci E,Hammer HB,Iagnocco A,Terslev L,González JM,Mérida JR,Carreño L

更新日期：2016-06-01 00:00:00

abstract：:Plasma fibronectin (FN) was measured in 17 patients with essential mixed cryoglobulinaemia (EMC) and in 17 normal subjects by single radial immunodiffusion (RID) and enzyme-linked immunosorbent assay (ELISA). In 9 patients the presence of FN in the cryoprecipitates was also assessed by immunoblotting. In the EMC group...

journal_title：Rheumatology international

authors： Toschi V,Renoldi P,Motta A,Cimminiello C,Arpaia G,Fiorini GF

更新日期：1987-01-01 00:00:00

abstract：:The authors report a rare case of a female patient diagnosed with mixed connective tissue disease (MCTD). After a few years in remission, the patient acquired herpes zoster infection followed by a disease flare. Disease activity was accompanied by the development of meningitis. To determine whether the meningitis was ...

journal_title：Rheumatology international

authors： Bodolay E,Diószeghy P,Demeter J,Bányai A,Csipö I,Szegedi G,Szekanecz Z

更新日期：2004-11-01 00:00:00

abstract：:Behçet's disease (BD) is a multi-system inflammatory disorder, in which cytokine balance is polarized to Th1. In this study, the cell surface molecule expression, Th1/Th2, inflammatory cytokine levels in blood, and synovial fluid of CD3(+) T lymphocytes in BD were investigated. The study group consisted of 10 BD, 10 a...

journal_title：Rheumatology international

authors： Aktas Cetin E,Cosan F,Kucuksezer UC,Bilgic S,Cagatay Y,Gul A,Deniz G

更新日期：2013-03-01 00:00:00

abstract：:Abnormal manifestations of central nervous system in system lupus erythematosus (SLE) patients are mainly caused by primary neuropsychiatric SLE (NP-SLE). We reported a new onset SLE patient who had secondary neuropsychiatric manifestations caused by Epstein-Barr virus (EBV) encephalitis. Although EBV has an uncertain...

journal_title：Rheumatology international

authors： Hongbo C,Hongzhen M,Lingzhi H,Maosheng X,Mei C

更新日期：2012-08-01 00:00:00

abstract：:The Juvenile Arthritis Multidimensional Assessment Report (JAMAR) is a new parent/patient-reported outcome measure that enables a thorough assessment of the disease status in children with juvenile idiopathic arthritis (JIA). We report the results of the cross-cultural adaptation and validation of the parent and patie...

journal_title：Rheumatology international

authors： Aggarwal A,Khubchandani R,Sawhney S,Rahman MT,Agarwal M,Consolaro A,Bovis F,Ruperto N,Paediatric Rheumatology International Trials Organisation (PRINTO).

更新日期：2018-04-01 00:00:00

abstract：:Here we evaluated whether 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) have beneficial effects for collagen-induced arthritis (CIA). DBA/1 mice were immunized with bovine type-II collagen and administered 100 mg/kg of pravastatin interperitoneally. We measured the effects of pravastatin for CIA...

journal_title：Rheumatology international

authors： Yamagata T,Kinoshita K,Nozaki Y,Sugiyama M,Ikoma S,Funauchi M

更新日期：2007-05-01 00:00:00

abstract：:In rheumatoid arthritis (RA), a disease characterized by bone loss, increased levels of serotonin have been reported. Recent studies have demonstrated a role for circulating serotonin as a regulator of osteoblastogenesis, inhibiting bone formation. Thus, we measured serum serotonin levels (SSL) in a Portuguese sample ...

journal_title：Rheumatology international

authors： Bernardes M,Vieira T,Lucas R,Pereira J,Costa L,Simões-Ventura F,Martins MJ

更新日期：2017-11-01 00:00:00