Isoniazid-triggered pure red cell aplasia in systemic lupus erythematosus complicated with myasthenia gravis.

Abstract:

:A 47-year-old woman who had been treated for systemic lupus erythematosus (SLE) with myasthenia gravis (MG) was admitted to our hospital with acute onset of severe anemia after administration of isoniazid. Pure red cell aplasia (PRCA) was confirmed by elevated serum iron levels, reticulocytopenia and bone marrow aspiration showing a remarkable reduction of erythroblasts. Finally, cyclosporine A successfully improved PRCA. Although both SLE and MG have the potential complication of PRCA, we report here a case of isoniazid-triggered PRCA.

journal_name

Rheumatol Int

authors

Nakamura H,Okada A,Kawakami A,Yamasaki S,Ida H,Motomura M,Imanishi D,Eguchi K

doi

10.1007/s00296-009-1113-2

subject

Has Abstract

pub_date

2010-11-01 00:00:00

pages

1643-5

issue

12

eissn

0172-8172

issn

1437-160X

journal_volume

30

pub_type

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