Abstract:
:We investigated the effect of chrysotherapy on the Fc and complement receptor binding activity of peripheral blood (PB) monocytes and peritoneal (PE) macrophages isolated from normal rats and rats with adjuvant induced arthritis. The adjuvant induced severe disease in Dark Agouti (DA) rats and less marked disease in J. C. Lewis (JC) rats. Gold treatment reduced the disease in DA rats but exacerbated the disease in JC rats. PB monocytes generally exhibited increased receptor activity after adjuvant injection. Gold treatment resulted in a simultaneous reduction of the PB monocyte receptor activity and increased the PE macrophage receptor activity. This was considered to be due to a direct effect of gold, since the Fc receptor activity of PE macrophages increased after in vitro gold treatment.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Haynes DR,Garrett IR,Vernon-Roberts Bdoi
10.1007/BF00270454subject
Has Abstractpub_date
1988-01-01 00:00:00pages
159-64issue
4eissn
0172-8172issn
1437-160Xjournal_volume
8pub_type
杂志文章abstract::The aims of this study were to assess the health-related quality of life (HRQoL) in patients with knee osteoarthritis (OA) using the Nottingham Health Profile (NHP) and to determine its relationships with conventional clinical measures and self-reported disability. One hundred and forty patients with knee OA (104 fema...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-1195-x
更新日期:2010-11-01 00:00:00
abstract::We have examined the way in which products of cultured human blood mononuclear cells activate human articular chondrocytes. Conditioned medium from mononuclear cells enhanced the production of prostaglandin E by cultured human chondrocytes and also stimulated fibrinolytic activity in these cultures. These two effects ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00541204
更新日期:1984-01-01 00:00:00
abstract::P wave dispersion (PWD) is a sign for the prediction of atrial fibrillation (AF). The aim of this study was to assess P wave dispersion and its relation with clinical and echocardiographic parameters in patients with rheumatoid arthritis (RA). Thirty RA patients (mean age 49 +/- 10 years) and 27 healthy controls (mean...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-007-0307-8
更新日期:2007-07-01 00:00:00
abstract::Schistosomiasis or bilharzia is a parasitic disease found in tropical countries. Most infections are subclinical but may progress to chronic form characterized most frequently by the presence of liver involvement and portal hypertension. We report a patient that presented chronic polyarthritis with positive rheumatoid...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1562-7
更新日期:2013-05-01 00:00:00
abstract::Circulating endothelial progenitor cells (EPCs) are reduced in patients with systemic lupus erythematosus (SLE). A reduced number of EPCs are associated with the presence of atherosclerosis in other populations. We sought to determine whether the reduction in EPC numbers in SLE is dependent on the presence of advanced...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1730-9
更新日期:2012-04-01 00:00:00
abstract::Anaemia of chronic disease (ACD) is a common extra-articular manifestation of rheumatoid arthritis (RA). Tumour necrosis factor alpha (TNF alpha) plays an important role in the development of ACD. The objective of the present study was to assess inhibition of in vitro colony-forming unit erythrocyte (CFUe) and blast-f...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00300811
更新日期:1994-01-01 00:00:00
abstract::Antibodies to DNA are quite specific for systemic lupus erythematosus (SLE) and occur in the majority of SLE patients. Therefore, their detection is an important diagnostic aid to the clinician. Detection of anti-dsDNA may precede the diagnosis of SLE by more than a year. Fluctuations in the level of anti-dsDNA in an ...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/BF00304496
更新日期:1991-01-01 00:00:00
abstract::Smoking produces substances that activate proinflammatory, prothrombotic and vasoconstrictive mediators via posttranslational carbamylation of proteins. As a new consequence of carbamylation, induction of anti-carbamylated autoantibodies were observed in rheumatoid arthritis (RA) patients, sometimes prior to onset of ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-016-3472-9
更新日期:2016-06-01 00:00:00
abstract::Diabetic muscular infarct (DMI) is a rare condition, which begins with acute onset of extremity pain and swelling. Patients usually have long-standing disease and poorly controlled diabetes mellitus (DM). Thigh muscle group is the most commonly involved side, while lower leg involvement is rare. We represent herein a ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1759-9
更新日期:2012-02-01 00:00:00
abstract::The aim of this study was to analyze the change of serum chemokins levels of CXCL16, CX3CL1/Fractalkine, and CXCL10/interferon-gamma inducible protein-10 (IP-10) with rheumatoid arthritis (RA), by infliximab treatment. The effects of infliximab treatment were studied in 23 patients with RA, over a period of 30 weeks. ...
journal_title:Rheumatology international
pub_type: 临床试验,杂志文章
doi:10.1007/s00296-006-0241-1
更新日期:2007-03-01 00:00:00
abstract::Sleep disturbances and problems are increased in ankylosing spondylitis (AS). But much is not known in a quantitative way about sleep problems and effect of treatments on AS. This study is aimed first, to investigate sleep disturbances in AS and secondly, to evaluate the effects of anti-TNF treatment on SD in AS. One ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-011-1907-x
更新日期:2012-07-01 00:00:00
abstract::Previous studies showed a link between systemic lupus erythematosus (SLE) and Epstein-Barr virus (EBV) infection. We sought to determine the features of serologic response to EBV in SLE patients and whether this response differs from those of systemic sclerosis (SSc) and primary antiphospholipid syndrome (PAPS) patien...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1573-4
更新日期:2012-01-01 00:00:00
abstract::In recent years, scientific efforts on the topic "gout" have focused on pathogenetic aspects. This has opened new strategies of anti-inflammatory therapy and has improved urate-lowering therapy. So far, a scientometric analysis of the topic "gout" has not been generated despite an increased need for it in times of mod...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-013-2805-1
更新日期:2013-11-01 00:00:00
abstract::To investigate the expression and effect of farnesoid X receptor (FXR) on systemic lupus erythematosus (SLE) liver dysfunction and indicate its hepatoprotective role and the immunomodulatory property. mRNA and protein levels of FXR were determined on the liver specimens of SLE patients with liver injury as well as MRL...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-011-1874-2
更新日期:2012-06-01 00:00:00
abstract::Systemic lupus erythematosus (SLE) is a chronic inflammatory disease that can lead to damage to several vital organs. Antiphospholipid syndrome (APS), manifesting as vascular thromboembolic events and morbidities of pregnancy in the presence of antiphospholipid antibodies (aPL), has been described in patients with SLE...
journal_title:Rheumatology international
pub_type: 信件
doi:10.1007/s00296-011-1826-x
更新日期:2012-03-01 00:00:00
abstract::To date, numerous genetic and epigenetic studies have been performed and provided a crucial step forward in our understanding of the pathogenesis of rheumatic diseases. However, most of the recent advances in the treatment of rheumatic diseases including biological therapies are not based on or even discrepant from th...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-018-4026-0
更新日期:2018-08-01 00:00:00
abstract::This study investigated the prevalence of antibody against annexin II (A2) in patients with antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE). It also explored the role of this antibody in thrombosis. Purified recombinant A2 was used in ELISA to measure the levels of IgG anti-A2 antibody in 101 AP...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1379-4
更新日期:2011-07-01 00:00:00
abstract::We studied causes of death (CoDs) between 1952 and 1991 assessed by a clinician before autopsy and then determined at autopsy by a pathologist in 369 subjects with rheumatoid arthritis (RA) and 370 subjects without RA (non-RA). We analysed clinical data for RA subjects between 1973 and 1991. In RA subjects, leading au...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0685-6
更新日期:2008-10-01 00:00:00
abstract::Pure red cell aplasia (PRCA) is a disease with important relationships to autoimmune mechanisms. Although some autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus, have been associated with PRCA, until this point no studies have described the association between PRCA and primary antiphos...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1387-4
更新日期:2012-05-01 00:00:00
abstract::The efficacy of balneotherapy in fibromyalgia syndrome (FS) has been well demonstrated, while controlled studies using mud packs are lacking. We performed a randomized clinical trial to evaluate the effects and the tolerability of mud-bath treatment in FS patients, who are poor responders to pharmacological therapy. E...
journal_title:Rheumatology international
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00296-007-0358-x
更新日期:2007-10-01 00:00:00
abstract::The atrioventricular conduction time (P-R interval) was determined in 189 women and 90 men with rheumatoid arthritis (RA). Only three women and one man were found to have pathological prolongation of the P-R interval. However, a significant prolongation of the P-R interval, within normal range, was seen in women with ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00541337
更新日期:1985-01-01 00:00:00
abstract::Systemic lupus erythematosus (SLE) is a chronic and complex autoimmune disease characterized by the production of autoantibodies against a spectrum of nuclear antigens. RANTES and its receptor CCR5 have been associated with the pathogenesis of SLE. The objective of this study is to analyze autoantibodies (DNA/RNA), al...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-013-2812-2
更新日期:2013-11-01 00:00:00
abstract::We aimed to investigate how orbital blood flow rates in patients with rheumatoid arthritis (RA) are affected by the active and remission phase of the disease. This prospective study included a total of 56 patients with RA (study group) and 24 control individuals (control group). All RA patients were divided into two g...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-019-04275-y
更新日期:2019-06-01 00:00:00
abstract::We report a case of sudden onset of late infection after TKA inflamed by anti-TNFalpha therapy, Infliximab, in a 54-year-old woman with RA. Infliximab therapy was started 3 years and 8 months after TKAs as a result of multiple arthritides showing high inflammation of RA. One week after the third administration of Infl...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-0948-x
更新日期:2010-01-01 00:00:00
abstract::A simple technique for fine-needle aspiration biopsy from the synovial membrane of arthritis knee joints preceded by lavage of the joint cavity is described. The procedure was atraumatic, well accepted, and could be performed on outpatients. Cells originating from the synovial membrane were obtained in 12 of 17 knees ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF00272430
更新日期:1988-01-01 00:00:00
abstract::The aims of this study were to assess the health-related quality of life (HRQoL) in patients with self-reported rheumatic diseases (RD), to classify self-reported rheumatic patients in groups according to their health state and to explore the associations between health status and sociodemographic variables. Data came...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-016-3517-0
更新日期:2016-09-01 00:00:00
abstract::Adult-onset Still's disease (AOSD) is a rare disease, and large epidemiological studies of this disease are limited. Furthermore, it has been difficult to show the incidence and characteristics of severe AOSD complications due to the rarity of this disease. The aim of our study was to describe the demographics of AOSD...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-016-3546-8
更新日期:2016-10-01 00:00:00
abstract::We report a case of a 39-year-old female with active systemic lupus erythematosus who complained of lethargy and weakness with a moderate renal impairment. Hypercalcemia was confirmed by laboratory examination. Her X-ray revealed significant ectopic calcinosis in subcutaneous tissue of bilateral hands, and Tc-99(m) me...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-016-3486-3
更新日期:2016-07-01 00:00:00
abstract::IgM, IgG and IgA class antibodies against Yersinia, Salmonella, Campylobacter and Borrelia were determined by enzyme-linked immunosorbent assay (ELISA) in a group of 340 unselected patients with a recent inflammatory joint disease. The control group consisted of 340 and 100 healthy blood donors using Borrelia-ELISA an...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/BF02274884
更新日期:1991-01-01 00:00:00
abstract::To translate and culturally adapt the Mayo Elbow Performance Score (MEPS), a widely used instrument for evaluating disability associated with elbow injuries, into Turkish (MEPS-T) and to determine psychometric properties of the translated version. The MEPS was translated into Turkish using published methodological gui...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-014-3201-1
更新日期:2015-06-01 00:00:00