Abstract：
:The Juvenile Arthritis Multidimensional Assessment Report (JAMAR) is a new parent/patient reported outcome measure that enables a thorough assessment of the disease status in children with juvenile idiopathic arthritis (JIA). We report the results of the cross-cultural adaptation and validation of the parent and patient versions of the JAMAR in the Paraguayan Spanish language. The reading comprehension of the questionnaire was tested in 10 JIA parents and patients. Each participating centre was asked to collect demographic, clinical data and the JAMAR in 100 consecutive JIA patients or all consecutive patients seen in a 6-month period and to administer the JAMAR to 100 healthy children and their parents. The statistical validation phase explored descriptive statistics and the psychometric issues of the JAMAR: the 3 Likert assumptions, floor/ceiling effects, internal consistency, Cronbach's alpha, interscale correlations, and construct validity (convergent and discriminant validity). A total of 51 JIA patients (2% systemic, 27.4% oligoarticular, 37.2% RF negative polyarthritis, 33.4% other categories) and 100 healthy children, were enrolled. The JAMAR components discriminated well healthy subjects from JIA patients. Notably, there was no significant difference between healthy subjects and their affected peers in the school-related problem variable. All JAMAR components revealed good psychometric performances. In conclusion, the Paraguayan Spanish version of the JAMAR is a valid tool for the assessment of children with JIA and is suitable for use both in routine clinical practice and clinical research.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Morel Ayala Z,Burgos-Vargas R,Consolaro A,Bovis F,Ruperto N,Paediatric Rheumatology International Trials Organisation (PRINTO).doi
10.1007/s00296-018-3964-xsubject
Has Abstractpub_date
2018-04-01 00:00:00pages
307-313issue
Suppl 1eissn
0172-8172issn
1437-160Xpii
10.1007/s00296-018-3964-xjournal_volume
38pub_type
杂志文章,多中心研究abstract：:The current study was to investigate the quantity and quality of researches in the field of ankylosing spondylitis, and to reveal the characteristics of worldwide productivity on this disease. This was a bibliometric study on ankylosing spondylitis using Web of Science. The numbers of papers, citations, research outpu...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-019-04308-6
更新日期：2019-06-01 00:00:00
abstract：:The objective of this study is to investigate the relationship between clinical features of ankylosing spondylitis (AS) and HLA-B27 status or its subtypes. Clinical data and blood samples were collected with patients' informed consent. Luminex liquid array combining polymerase chain reaction-sequence specific oligonuc...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-008-0743-0
更新日期：2009-02-01 00:00:00
abstract：:PXK was identified as a novel candidate gene for systemic lupus erythematosus (SLE) from genome-wide association studies (GWAS) in Caucasians. But a recent replication study in Hong Kong Chinese reported that PXK was not associated with SLE. The aim of this study was to determine whether PXK is associated with SLE in ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1789-3
更新日期：2012-01-01 00:00:00
abstract：:The distribution of tumour necrosis factor alpha (TNF alpha) in rheumatoid synovium has been investigated. Ten rheumatoid synovia were compared with seven normal synovia and a range of other tissues, using one polyclonal and six monoclonal antibodies. A common staining pattern was obtained with five reagents. Absence ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00290246
更新日期：1991-01-01 00:00:00
abstract：:Articular involvement is a frequent extrahepatic manifestation of hepatitis C virus (HCV) infection. The distinction between HCV-related polyarthropathy and true RA may be very difficult, especially with recent onset RA before articular damage and erosions develop. The objective of the study is to assess the diagnosti...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-1225-8
更新日期：2011-01-01 00:00:00
abstract：:We describe a patient with bronchiolitis obliterans organizing pneumonia (BOOP) requiring respiratory support and treated with corticosteroids and cytoxan for presumed Wegener's granulomatosis (WG). The diagnosis of WG was based on clinical presentation and strongly positive stains for anti-neutrophilic cytoplasmic an...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s002960000095
更新日期：2001-04-01 00:00:00
abstract：:To determine the forms and characteristics of rheumatic diseases whose initial presentation mimics septic arthritis. Retrospective study of 398 patients hospitalized between 1979 and 2005 for arthritis diagnosed and treated as septic. In 10 cases, initial presentation of a rheumatic disease was highly suggestive of se...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-012-2364-x
更新日期：2013-08-01 00:00:00
abstract：:Antibodies to citrullinated proteins have been described in patients with rheumatoid arthritis (RA) and these appear to be the most specific markers of the disease. Our objective was to determine the frequency of antibodies to cyclic citrullinated peptides (CCPs) in patients with RA and the association of anti-CCP ant...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-008-0570-3
更新日期：2008-08-01 00:00:00
abstract：:The objective of the study is to investigate the clinical characteristics and long-term prognosis including flares and organ damage in patients with giant cell arteritis (GCA) from a tertiary referral centre and compare these features in different subgroups. In this retrospective observational study, patients with GCA...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-020-04730-1
更新日期：2021-02-01 00:00:00
abstract：:Bisphosphonates such as alendronate, risedronate and zoledronate have revolutionised the treatment for osteoporosis and Paget's disease. These drugs reduce fracture risk and probably mortality in patients with osteoporosis. However, they have a long in vivo half-life following cessation and may be associated with dela...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-013-2771-7
更新日期：2013-09-01 00:00:00
abstract：:The aims of this study were to assess the health-related quality of life (HRQoL) in patients with knee osteoarthritis (OA) using the Nottingham Health Profile (NHP) and to determine its relationships with conventional clinical measures and self-reported disability. One hundred and forty patients with knee OA (104 fema...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-1195-x
更新日期：2010-11-01 00:00:00
abstract：:We have recently reported on two cases of scleroderma patients with ANCA-associated vasculitis for the first time in Korea. In order to explore the nature of this disease combination, we pooled together all the previously known cases and statistically analyzed them. Out of the 50 selected cases, survival analysis was ...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-005-0011-5
更新日期：2006-03-01 00:00:00
abstract：:As has been shown by a number of working groups, primary fibromyalgia syndrome does not represent a single clinical entity. It is possible to distinguish between a subgroup with high pain sensitivity and no associated psychiatric condition, a second and a third subgroup characterized by depression associated with fibr...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-007-0403-9
更新日期：2007-09-01 00:00:00
abstract：:Behçet's disease (BD) commonly presents with articular manifestations and thrombotic vasculopathy. Arthritis of BD characteristically demonstrates a recurrent and nondestructive course. The pathobiological basis of the thrombotic vasculopathy and protective factors against cartilage destruction in arthritis of BD have...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-003-0324-1
更新日期：2004-03-01 00:00:00
abstract：:Wegener granulomatosis (WG) is a necrotizing granulomatous vasculitis that predominantly affects airways and kidneys. But central nervous system involvement (7-11%) is an uncommon. Massive ICH may occur in the course of WG, and this serious condition is related with high risk of mortality. Therefore, the new treatment...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-1954-3
更新日期：2012-06-01 00:00:00
abstract：:The aim of the study was to assess the possible association between type II collagen turnover seromarkers and disease profile in patients with axial spondyloarthritis (SpA) and psoriatic arthritis (PsA). Outpatients with axial SpA (n = 110) or PsA (n = 101) underwent clinical examination including disease activity mea...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-015-3397-8
更新日期：2016-04-01 00:00:00
abstract：:The American Rheumatism Association (ARA) clinical criteria have been tested in systemic lupus erythematosus (SLE), progressive systemic sclerosis, polyarteritis nodosa and polymyositis/dermatomyositis. Hospital admissions from a defined population over the same period were studied. Increased weighting of the scores f...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00541261
更新日期：1981-01-01 00:00:00
abstract：:Histoplasmosis is an important cause of morbidity in endemic areas of the USA. Infection is often asymptomatic but can cause a broad spectrum of pathology. Less commonly, histoplasmosis can present with a wide-range of rheumatologic manifestations. The aim of this review is to provide a synopsis of the rheumatologic m...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-013-2816-y
更新日期：2013-12-01 00:00:00
abstract：:The minor allele of the non-synonymous single nucleotide polymorphism (SNP) +1858C>T within the PTPN22 gene has now been unequivocally confirmed as conferring susceptibility to RA in population from Europe and America, but not in population from Asia. The aim of this study was to jointly address and integrate these se...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1705-x
更新日期：2012-03-01 00:00:00
abstract：:Protein synthesis in all cells is readily interrupted by environmental stresses such as hyperthermia. However, stressed cells also have mechanisms which, even under conditions where normal protein synthesis is completely inhibited, allow them to synthesise a group of highly conserved proteins--the so-called heat shock...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/BF00541323
更新日期：1990-01-01 00:00:00
abstract：:Several studies have shown a negative association between smoking and primary Sjögren's syndrome (pSS), and smoking may interfere with the immune response. The purpose of this study was to investigate if smoking affects disease activity and disease phenotype in pSS. In this cross-sectional study, consecutive pSS patie...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-019-04335-3
更新日期：2019-09-01 00:00:00
abstract：:Aseptic loosening is the predominant cause of total hip implant failure. It has been assumed that a layer or membrane, containing macrophages, fibroblasts and vascular endothelial cells, of synovial-like tissue develops at the implant-to-bone interface almost invariably and, with time, somehow leads to loosening of th...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s002960050037
更新日期：1998-01-01 00:00:00
abstract：:Familial Mediterranean fever (FMF) is an autosomal recessive, inherited autoinflammatory disease characterized by recurrent, self-limited attacks of fever and inflammation of serosal surfaces. There is an explosion of the data regarding inflammatory markers in FMF and clinical effects of chronic inflammation on the di...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-2281-4
更新日期：2012-12-01 00:00:00
abstract：:Serotonin antagonists show impressive analgesic efficacy in rheumatoid arthritis, osteoarthritis (OA) or fibromyalgia; however, this effect is not well understood. We examined the mechanism of serotonin-induced inflammation and its antagonists in OA. Serotonin receptor subtypes and COX-2 were analysed by RT-PCR from s...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-008-0564-1
更新日期：2008-08-01 00:00:00
abstract：:Severe acute respiratory syndrome coranovirus-2 (SARS-CoV-2) infection has become an important health-care issue worldwide. The coronavirus disease 2019 (COVID-19) has also raised concerns among patients with inflammatory rheumatic conditions and their treating physicians. There are emerging data regarding the potenti...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-020-04635-z
更新日期：2020-10-01 00:00:00
abstract：:The authors report an unusual case of myelodysplastic syndrome (MDS) associated with ankylosing spondylitis (AS). A 40-year-old-man with MDS presented with chronic low back pain for 6 years. Four years ago, MDS was diagnosed during routine blood analysis for the work-up of his articular complaints. His initial articul...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-008-0735-0
更新日期：2009-04-01 00:00:00
abstract：:The objective of the study was to evaluate synovial tissue receptor activator of nuclear factor-κβ ligand (RANKL) and osteoprotegerin (OPG) as biomarkers of disease activity, progressive joint damage, and therapeutic response, during cytokine blockade in rheumatoid arthritis (RA). Patients with active RA entered a ran...
journal_title：Rheumatology international
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00296-009-1191-1
更新日期：2010-11-01 00:00:00
abstract：:Genetic polymorphisms in cytokine genes, which influence gene expression, may have an important impact on SLE susceptibility and severity. The aim of this study was to examine the possible influence of two functional polymorphisms in cis-regulatory regions of IL12B gene in the susceptibility and clinical symptoms of S...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1547-6
更新日期：2012-01-01 00:00:00
abstract：:The presence of specific anti-Proteus antibodies in active, rheumatoid arthritis (RA) patients, has been demonstrated by four different techniques: indirect bacterial agglutination, ELISA, Western blotting and immunofluorescence. Furthermore, anti-HLA-DR4 tissue typing sera have been shown to bind to Proteus microorga...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/BF00271885
更新日期：1989-01-01 00:00:00
abstract：:Behçet's disease (BD) is a multi-system inflammatory disorder, in which cytokine balance is polarized to Th1. In this study, the cell surface molecule expression, Th1/Th2, inflammatory cytokine levels in blood, and synovial fluid of CD3(+) T lymphocytes in BD were investigated. The study group consisted of 10 BD, 10 a...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-012-2446-9
更新日期：2013-03-01 00:00:00
