Rheumatoid arthritis masquerading as acromegaly recurrence: report of two cases.

Abstract:

:Acromegaly is a chronic endocrinopathy characterized by hypersecretion of growth hormone (GH) and consequently of insulin-like growth factor-1 (IGF-1). The arthropathy in acromegaly is the most frequent and important cause of morbidity and functional disability in acromegaly. Rheumatoid arthritis (RA) is a rarely reported clinical situation in patients with acromegalic. We herein report 57- and 45-year-old two women, who complained bilateral, symmetric pain, swelling and morning stiffness in the joints of hands after optimal acromegaly treatment resembling acromegaly arthropathy. There was not arthralgia in other joints of the patients. Laboratory and radiological evaluations were carried out. After excluding the acromegaly activation and arthropathy by GH and IGF-1 measurement, according to clinical presentation, laboratory and radiological assessments, patients were diagnosed as RA.

journal_name

Rheumatol Int

authors

Aydın Y,Coşkun H,Kır S,Yazici S,Kudaş Ö,Güngör A

doi

10.1007/s00296-010-1490-6

subject

Has Abstract

pub_date

2012-09-01 00:00:00

pages

2913-5

issue

9

eissn

0172-8172

issn

1437-160X

journal_volume

32

pub_type

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