Abstract:
:Acromegaly is a chronic endocrinopathy characterized by hypersecretion of growth hormone (GH) and consequently of insulin-like growth factor-1 (IGF-1). The arthropathy in acromegaly is the most frequent and important cause of morbidity and functional disability in acromegaly. Rheumatoid arthritis (RA) is a rarely reported clinical situation in patients with acromegalic. We herein report 57- and 45-year-old two women, who complained bilateral, symmetric pain, swelling and morning stiffness in the joints of hands after optimal acromegaly treatment resembling acromegaly arthropathy. There was not arthralgia in other joints of the patients. Laboratory and radiological evaluations were carried out. After excluding the acromegaly activation and arthropathy by GH and IGF-1 measurement, according to clinical presentation, laboratory and radiological assessments, patients were diagnosed as RA.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Aydın Y,Coşkun H,Kır S,Yazici S,Kudaş Ö,Güngör Adoi
10.1007/s00296-010-1490-6subject
Has Abstractpub_date
2012-09-01 00:00:00pages
2913-5issue
9eissn
0172-8172issn
1437-160Xjournal_volume
32pub_type
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