Abstract：
:The efficacy of balneotherapy in fibromyalgia syndrome (FS) has been well demonstrated, while controlled studies using mud packs are lacking. We performed a randomized clinical trial to evaluate the effects and the tolerability of mud-bath treatment in FS patients, who are poor responders to pharmacological therapy. Eighty patients with primary FS, according to ACR criteria, were randomly allocated to two groups: 40 were submitted to a cycle of 12 mud packs and thermal baths, and 40 were considered as controls. At baseline, after thermal treatment and after 16 weeks, patients were evaluated by FIQ, tender points count, VAS for "minor" symptoms, AIMS1 and HAQ. Control patients were assessed at the same time periods. A significant improvement of all evaluation parameters after mud-bath therapy and after 16 weeks was observed. Mud packs were well tolerated and no drop-outs were recorded. Our results suggest the efficacy and the tolerability of mud-bath treatment in primary FS.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Fioravanti A,Perpignano G,Tirri G,Cardinale G,Gianniti C,Lanza CE,Loi A,Tirri E,Sfriso P,Cozzi Fdoi
10.1007/s00296-007-0358-xsubject
Has Abstractpub_date
2007-10-01 00:00:00pages
1157-61issue
12eissn
0172-8172issn
1437-160Xjournal_volume
27pub_type
杂志文章,多中心研究,随机对照试验abstract：:We examined the intracellular mechanisms of substance P induced oxyradical production in rheumatoid synovial cells by the luminol-dependent chemiluminescence method. After stimulation with substance P (30 microM), single synovial A (macrophage-like) or B (fibroblast-like) cells released oxyradicals such as superoxide ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF01419729
更新日期：1996-01-01 00:00:00
abstract：:The induction of experimental arthritis in rhesus monkeys was studied by intradermal immunization of bovine type II collagen and antigens derived from Mycobacterium tuberculosis, Streptococcus pyogenes, and Eubacterium aerofaciens. The tested bacterial antigens proved to be not arthrogenic. Bovine type II collagen ind...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF02274777
更新日期：1990-01-01 00:00:00
abstract：:Systemic lupus erythematosus (SLE) severity, reflecting both disease intensity and duration, is heterogeneous making it challenging to study in administrative databases where severity may confound or mediate associations with outcomes. Garris et al. developed an administrative claims-based algorithm employing claims o...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-019-04477-4
更新日期：2020-02-01 00:00:00
abstract：:The fibromyalgia syndrome (FMS) is a chronic, widespread pain disorder of unknown etiology. It has been suggest that familial component, environmental factors, endocrine and neurotransmitter alterations, and psychological factors may contribute to the development of FMS. The role of melatonin in FMS is unclear. Some s...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-2315-y
更新日期：2013-06-01 00:00:00
abstract：:Baseline and sequential liver biopsies were performed in ten patients with rheumatoid arthritis (RA) treated with methotrexate (MTX) for more than 4 years. Liver biopsies were performed in all patients before the initiation of MTX therapy and were repeated after reaching a cumulative dose of 1500 mg or more. In four p...
journal_title：Rheumatology international
pub_type： 临床试验,杂志文章
doi：10.1007/BF00246875
更新日期：1992-01-01 00:00:00
abstract：:A meta-analysis was done with the final data from three trials that provided the first results relating to efficacy and safety of the new sustained-release (SR) formulation of etodolac versus established nonsteroidal anti-inflammatory drugs (NSAIDs) in the treatment of osteoarthritis (OA) of the knee. The studies were...
journal_title：Rheumatology international
pub_type： 杂志文章,meta分析
doi：10.1007/BF00290280
更新日期：1993-01-01 00:00:00
abstract：:The objective of the study is to investigate the clinical characteristics and long-term prognosis including flares and organ damage in patients with giant cell arteritis (GCA) from a tertiary referral centre and compare these features in different subgroups. In this retrospective observational study, patients with GCA...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-020-04730-1
更新日期：2021-02-01 00:00:00
abstract：:C4A and C4B levels were measured in serum from 246 normal individuals. Complement-mediated solubilisation, assayed using alkaline phosphatase anti-alkaline phosphatase immune complexes (IC), correlated with both C4A and C4B levels. However, C4A and C4B levels showed no correlation with solubilisation of bovine serum a...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00302150
更新日期：1992-01-01 00:00:00
abstract：:In patients suffering from ankylosing spondylitis (AS) HLA-B27 determination by means of the microlymphocytotoxicity test (MLCT) sometimes gives equivocal or false-negative results even though it has been performed with meticulous care. These failures of the test did not arise when the isolated mononuclear cells (MNC)...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00301265
更新日期：1993-01-01 00:00:00
abstract：:There are contradictory results in the relevant literature about the relationship between objective determinants of craniocervical posture and temporomandibular disorder (TMD), whereas no study has worked on ankylosing spondylitis (AS) and TMD relationship. We conducted this study to test the predictors of TMD in AS p...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-020-04563-y
更新日期：2020-06-01 00:00:00
abstract：:The aim of this study was to analyze the change of serum chemokins levels of CXCL16, CX3CL1/Fractalkine, and CXCL10/interferon-gamma inducible protein-10 (IP-10) with rheumatoid arthritis (RA), by infliximab treatment. The effects of infliximab treatment were studied in 23 patients with RA, over a period of 30 weeks. ...
journal_title：Rheumatology international
pub_type： 临床试验,杂志文章
doi：10.1007/s00296-006-0241-1
更新日期：2007-03-01 00:00:00
abstract：:Tribal differences are demonstrated in the presentation of lupus in Omani Gulf Arabs (OGA) and Omani Arabs of Persian descent (OAP), both groups resident in and indigenous to the Sultanate of Oman. The OAP have a lower risk of joint complications, skin rash, and dsDNA antibodies than OGA (beta coefficient and 95% conf...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-001-0151-1
更新日期：2002-01-01 00:00:00
abstract：:Sarcoidosis is a chronic, multisystemic, non-caseating granulomatous disease of unknown etiology. Nasopharyngeal involvement is very rare in sarcoidosis. The objective of this report was to evaluate a rare involvement of sarcoidosis. This report includes a case of nasopharyngeal sarcoidosis. A 51-year-old female with ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-1866-2
更新日期：2012-05-01 00:00:00
abstract：:Pancreatitis is uncommon in systemic lupus erythematosus (SLE) and is rarely reported in children, possibly being related to macrophage activation syndrome (MAS). The incidence of MAS in children with lupus pancreatitis is unknown, as is their prognosis. In this case-based review, we report a pediatric patient with SL...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-019-04388-4
更新日期：2020-05-01 00:00:00
abstract：:We report a case of an association of four autoimmune diseases in a 15-year-old girl and we discuss the etiopathogenic of this association and difficulties of treatment. ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-0988-2
更新日期：2010-04-01 00:00:00
abstract：:To describe levels of daily physical activity and examine the extent of agreement between self-reported and objectively measured indices of physical activity, and characteristics associated with under or overestimated physical activity among persons with osteoarthritis (OA). Using cross-sectional data from the 2003-20...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-016-3537-9
更新日期：2016-10-01 00:00:00
abstract：:The aim of this study was to compare the efficacy of sodium hyaluronate (SH) injection with the most common treatment methods, intraarticular steroid injection and physical therapy modalities in patients with adhesive capsulitis (AC). A total of 95 shoulders of 90 patients were included in the study and were randomize...
journal_title：Rheumatology international
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00296-005-0022-2
更新日期：2006-04-01 00:00:00
abstract：:The ultrastructural localisation of class II and macrophage antigens has been sought in the intimal layer of the human synovium. The cells described as type A in early morphological studies are shown to express both class II antigens and two markers of the macrophage/monocyte lineage of cells, OKM1 and MAB 24. The mor...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00270456
更新日期：1988-01-01 00:00:00
abstract：:Pancreatitis is a relatively rare but severe manifestation in systemic lupus erythematosus (SLE) patients. We report a case of a 39-year-old woman with previous SLE diagnose treated with prednisone and mycophenolate mofetil who developed an acute pancreatitis complicated by pancreatic pseudocysts within the context of...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-0964-x
更新日期：2010-03-01 00:00:00
abstract：:Chronic inflammation starting early in life and continuing into adulthood may predispose children with Juvenile Idiopathic Arthritis (JIA) to cardiovascular (CV) complications. To compare non-invasive CV risk markers- left ventricular mass index (LVMi), brachial artery flow mediated dilatation (FMD) and carotid artery...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-020-04689-z
更新日期：2021-02-01 00:00:00
abstract：:It is proposed that synovial fluid biomarkers may help in differentiating the type of arthritis. The aim of study is to determine whether synovial fluid adenosine deaminase (ADA) and high-sensitivity C-reactive protein (hs-CRP) can be useful in this regard. A total of 75 patients with knee monoarthritis that were admi...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1602-3
更新日期：2012-01-01 00:00:00
abstract：:To study the mechanisms of chondrocyte damage, chondrocyte cytotoxicity as shown by chromium-51 release induced by polymorphonuclear leukocytes (PMNLs) was examined. PMNLs significantly enhanced chondrocyte cytotoxicity in the presence of phorbol dibutyrate. This chondrocyte damage was abolished by the addition of cat...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00274933
更新日期：1992-01-01 00:00:00
abstract：:Systemic sclerosis is a connective tissue disease, which may lead to elevated pulmonary arterial pressure due to pulmonary arterial hypertension and/or left ventricular diastolic dysfunction. Uric acid (UA) has been shown to be elevated in patients with pulmonary hypertension (PH) and heart failure. We aimed to invest...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1557-4
更新日期：2011-02-01 00:00:00
abstract：:Acute leukemia is uncommonly seen with rheumatoid arthritis during or following treatment with low-dose methotrexate, a safe and effective treatment for the arthritic condition. We describe here a 68-year-old woman with rheumatoid arthritis who developed acute erythroleukemia during low-dose methotrexate therapy (tota...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-004-0502-9
更新日期：2005-05-01 00:00:00
abstract：:The aim of the present study was to evaluate the effect of long-term leflunomide and methotrexate (MTX) therapy during the course of rheumatoid arthritis (RA) estimated by digital X-ray radiogrammetry (DXR) and computer-aided joint space analysis (CAJSA) as diagnostic tools for the quantification of disease-related pe...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-008-0682-9
更新日期：2009-01-01 00:00:00
abstract：:Sound epidemiological data are a basic requirement for decision making on the allocation of health care resources. Unfortunately, this is not the case in Estonia, where the paucity of epidemiological data has impeded health care planning for rheumatic conditions. The current paper presents the first effort to explore ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-012-2473-6
更新日期：2013-04-01 00:00:00
abstract：:The Peptidyl arginine deiminase, type IV (PADI4) gene has been suggested to have an association with rheumatoid arthritis (RA) in several populations. But its role in Chinese RA is not clarified. We investigated five single-nucleotide polymorphisms (SNPs) of PADI4 as PADI4-89 (rs11203366), PADI4-90 (rs11203367), PADI4...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1519-x
更新日期：2011-12-01 00:00:00
abstract：:Analyses of the synovial tissue and fluid T lymphocytes obtained from patients with rheumatoid arthritis revealed multiple functional defects in the regulation of autologous blood B cell differentiation into cells secreting immunoglobulin. These abnormalities were not found in peripheral blood T lymphocytes from the s...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00541164
更新日期：1982-01-01 00:00:00
abstract：:Methotrexate (MTX) can be toxic to patients suffering from end stage renal disease (ESRD) on hemodialysis even at low doses. This increase in toxicity is more notable in terms of bone marrow suppression in the form of pancytopenia. Many methods of elimination including dialysis itself have been proven ineffective, and...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-011-2041-5
更新日期：2011-12-01 00:00:00
abstract：:We report on a 7-month-old infant with Kawasaki disease (KD) whose only manifestations were high-grade fever of 7 days duration, "non-toxic look" and "extreme irritability", thereby not meeting the criteria for the classical or the atypical form of the disease. The diagnosis was confirmed by the demonstration of a sol...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-0899-2
更新日期：2009-07-01 00:00:00
