Abstract:
:This article describes the historical development of the prophylactic use of antibiotics in cell culture as well as their effects on cells. The influence of antibiotics on cell morphology, cellular degeneration and cell death and cellular function is summarized. Cellular DNA as well as protein synthesis are affected which can lead to interference with, or even changes in, metabolic processes. Such effects must be considered in cell culture research. As antibiotics are used in multifold ways, the otherwise standardized conditions in cell culture are no longer comparable. The prophylactic use of antibiotics is rejected for scientific reasons.
journal_name
Cytotechnologyjournal_title
Cytotechnologyauthors
Kuhlmann Idoi
10.1007/BF00749764subject
Has Abstractpub_date
1995-06-01 00:00:00pages
95-105issue
2eissn
0920-9069issn
1573-0778journal_volume
19pub_type
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