Amorphous silica coatings on magnetic nanoparticles enhance stability and reduce toxicity to in vitro BEAS-2B cells.

abstract：:The primary objective of this study was to correlate the emission of macro and nanoparticles released during the process of metal inert gas/metal active gas (MIG/MAG) of stainless steel with different gas mixtures. Using different gas mixtures with different heat inputs, it was possible to determine fume formation rat...

journal_title：Inhalation toxicology

authors： Pacheco RP,Gomes JF,Miranda RM,Quintino ML

更新日期：2017-05-01 00:00:00

abstract：:A subchronic, nose-only inhalation study compared the effects of mainstream smoke from a 1R4F research cigarette to that of a 2R4F research cigarette. Male and female rats were exposed for 1 h/day, 5 days/wk, for 13 wk to mainstream smoke at 0, 0.06, 0.20, or 0.80 mg wet total particulate matter per liter of air. Clin...

journal_title：Inhalation toxicology

authors： Higuchi MA,Sagartz J,Shreve WK,Ayres PH

更新日期：2004-01-01 00:00:00

abstract：:Chronic exposure to chlorine gas has been shown to cause occupational asthma. Acute inhalation of chlorine is known to cause airway inflammation and induce airway nitric oxide formation. Exhaled nitric oxide may therefore be a marker of airway damage after chlorine gas exposure. After accidental chlorine gas exposure ...

journal_title：Inhalation toxicology

authors： Grasemann H,Tschiedel E,Groch M,Klepper J,Ratjen F

更新日期：2007-08-01 00:00:00

abstract：:Epidemiologic studies have provided strong evidence that episodic exposure to ambient particulate matter is associated with increases in morbidity and mortality. These adverse effects have been demonstrated at concentrations far below the National Ambient Air Quality Standard (NAAQS), and thus, the biological plausibi...

journal_title：Inhalation toxicology

authors： Gordon T,Gerber H,Fang CP,Chen LC

更新日期：1999-01-01 00:00:00

abstract：:Objectives: This follow-up study set out to evaluate the natural course and radiographic progression of silicosis among ceramic workers and describe the risk factors related with disease progression. Materials and methods: We retrospectively analyzed the data of ceramic workers with silicosis who were referred to our ...

journal_title：Inhalation toxicology

authors： Karataş M,Gündüzöz M,Büyükşekerci M,Özakıncı OG,Nadir Öziş T

更新日期：2019-02-01 00:00:00

abstract：INTRODUCTION:Air pollution causes respiratory symptoms and pulmonary disease. Airway inflammation may be involved in the mechanism also for cardiovascular disease. Wood smoke is a significant contributor to air pollution, with complex and varying composition. We examined airway effects of two kinds of wood smoke in a c...

journal_title：Inhalation toxicology

authors： Stockfelt L,Sallsten G,Olin AC,Almerud P,Samuelsson L,Johannesson S,Molnar P,Strandberg B,Almstrand AC,Bergemalm-Rynell K,Barregard L

更新日期：2012-01-01 00:00:00

abstract：:Objectives: To (1) design and build a low-cost exposure chamber system for whole-body exposure of rodents to electronic cigarette aerosol, (2) provide detailed instructions with particular focus on automated e-cigarette activation, and (3) develop a simple mathematical model for aerosol levels in the exposure chamber....

journal_title：Inhalation toxicology

authors： Hilpert M,Ilievski V,Coady M,Andrade-Gutierrez M,Yan B,Chillrud SN,Navas-Acien A,Kleiman NJ

更新日期：2019-01-01 00:00:00

abstract：:The Provisional Advisory Level (PAL) protocol was applied to estimate inhalation exposure limits for phosgene (CG). Three levels (PAL 1, PAL 2, and PAL 3), distinguished by severity of toxic effects, are developed for 24-hour, 30-day, 90-day, and 2-year durations of potential drinking water and inhalation exposures fo...

journal_title：Inhalation toxicology

authors： Glass D,McClanahan M,Koller L,Adeshina F

更新日期：2009-12-01 00:00:00

abstract：:Because of the interest attendant to establishing an 8-h ozone (O(3)) federal air quality standard, acute pulmonary function responses to prolonged (6.6 to 8 h) O(3) exposure between 0.08 and 0. 24 ppm have been examined in chamber studies. Given time constraints for O(3) concentration changes in room-sized chambers a...

journal_title：Inhalation toxicology

authors： Adams WC

更新日期：2000-04-01 00:00:00

abstract：:In Germany in 2006 a series of rapidly developing and sometimes severe cases of pulmonary health impairment were observed after normal use of the "Magic Nano Glass & Ceramic" spray and "Magic Nano Bath" spray. In contrast, the previously marketed "Magic Nano" pump spray product (handheld trigger device without propell...

journal_title：Inhalation toxicology

authors： Pauluhn J,Hahn A,Spielmann H

更新日期：2008-11-01 00:00:00

abstract：:The understanding of historical ambient asbestos concentrations is critical to exposure mapping and retrospective health impact studies involving asbestos related diseases. Two presentations at the University of Montana Center for Environmental Health Sciences Asbestos Conference (July 28, 2005) introduced novel metho...

journal_title：Inhalation toxicology

authors： Webber JS,Getman M,Ward TJ

更新日期：2006-11-01 00:00:00

abstract：:Objective: Ethanol is used as a solvent for flavoring chemicals in some electronic cigarette (e-cigarette) liquids (e-liquids). However, there are limited data available regarding the effects of inhalation of ethanol on blood alcohol concentration (BAC) during e-cigarette use. In this study, a modified physiologically...

journal_title：Inhalation toxicology

authors： More SL,Thornton SA,Maskrey JR,Sharma A,de Gandiaga E,Cheng TJ,Fung ES,Bernal AJ,Madl AK

更新日期：2020-01-01 00:00:00

abstract：:The irritants acrolein, acetaldehyde, and acetic acid induce a rapid sensory nerve-mediated nasal vasodilatory response in the rat. The aim of the current study was to examine acute nasal sensory nerve-mediated acute responses to an irritant ester vapor, ethyl acrylate. For this purpose, the upper respiratory tract of...

journal_title：Inhalation toxicology

authors： Morris JB

更新日期：2002-06-01 00:00:00

abstract：:Propylene glycol mono-t-butyl ether (PGMBE) is a widely used solvent in industry and in consumer products, posing a potential for human exposure via inhalation or dermal routes. Toxicokinetic studies were conducted on F344/N rats and B6C3F1 mice of both sexes to evaluate single or repeated dose, species, and/or sex di...

journal_title：Inhalation toxicology

authors： Dill J,Fuciarelli A,Lee K,Mellinger K,Burka L,Roycroft J

更新日期：2004-05-01 00:00:00

abstract：CONTEXT:Heart rate alterations associated with exposure to particulate matter (PM) and gaseous pollutants have been observed in epidemiological studies and animal experiments. Nevertheless, the time-lag of these associations is still unclear. OBJECTIVE:Determine the association at different time-lags between the compl...

journal_title：Inhalation toxicology

authors： Ramos-Bonilla JP,Breysse PN,Dominici F,Geyh A,Tankersley CG

更新日期：2010-03-01 00:00:00

abstract：CONTEXT:Eleven carbohydrates and natural product ingredients were added individually to experimental cigarettes. OBJECTIVE:A battery of tests was used to compare toxicity of mainstream smoke from these experimental cigarettes to matched control cigarettes without test ingredients. MATERIALS AND METHODS:Smoke fraction...

journal_title：Inhalation toxicology

authors： Coggins CR,Wagner KA,Werley MS,Oldham MJ

更新日期：2011-06-01 00:00:00

abstract：:The lung toxicity of inhalable polymer materials is normally carried out by evaluation of the histopathology responses of rat lungs to repeat, nose-only, exposures of an inhalable aerosol of material in a 13-wk subchronic repeat dose toxicity study. The introduction of transcriptomics into toxicology has allowed the c...

journal_title：Inhalation toxicology

authors： Carthew P,Fletcher S,White A,Harries H,Weber K

更新日期：2006-04-01 00:00:00

abstract：:Antisense oligonucleotides (ASOs) bind and facilitate degradation of RNA and inhibit protein expression in pathways not easily targeted with small molecules or antibodies. Interleukin (IL)-4 and IL-13 potentiate signaling through the shared IL-4 receptor-α (IL-4Rα) subunit of their receptors. ASO targeting of IL-4Rα m...

journal_title：Inhalation toxicology

authors： Fey RA,Templin MV,McDonald JD,Yu RZ,Hutt JA,Gigliotti AP,Henry SP,Reed MD

更新日期：2014-07-01 00:00:00

abstract：CONTEXT:There have been no animal studies of the health effects of repeated inhalation of mixtures representing downwind pollution from coal combustion. Environmental exposures typically follow atmospheric processing and mixing with pollutants from other sources. OBJECTIVE:This was the fourth study by the National Env...

journal_title：Inhalation toxicology

authors： Mauderly JL,Barrett EG,Gigliotti AP,McDonald JD,Reed MD,Seagrave J,Mitchell LA,Seilkop SK

更新日期：2011-05-01 00:00:00

abstract：:In order to evaluate the chronic effect of polymerized toner particles on the lung, inflammation- and fibrosis-related genes were analyzed and 8-hydroxydeoxyguanosine (8-OHdG) was examined by using the lung tissue of rats subjected to 24 months of toner inhalation exposure. Wistar female rats were divided into four gr...

journal_title：Inhalation toxicology

authors： Morimoto Y,Hirohashi M,Kasai T,Oyabu T,Ogami A,Myojo T,Murakami M,Nishi K,Kadoya C,Todoroki M,Yamamoto M,Kawai K,Kasai H,Tanaka I

更新日期：2009-09-01 00:00:00

abstract：:The World Health Organization identified urban outdoor air pollution as the eighth highest mortality risk factor in high-income countries. Exposure to ambient pollutants such as ozone (O3) increases the number of hospital admissions. O3 is a highly reactive gas that reacts with cells lining the airways, producing the ...

journal_title：Inhalation toxicology

authors： González-Guevara E,Martínez-Lazcano JC,Custodio V,Hernández-Cerón M,Rubio C,Paz C

更新日期：2014-07-01 00:00:00

abstract：:Background: While the role of lysosomal membrane permeabilization (LMP) in NP-induced inflammatory responses has been recognized, the underlying mechanism of LMP is still unclear. The assumption has been that zinc oxide (ZnO)-induced LMP is due to Zn2+; however, little is known about the role of ZnO nanoparticles (NP)...

journal_title：Inhalation toxicology

authors： Ziglari T,Anderson DS,Holian A

更新日期：2020-02-01 00:00:00

abstract：:Ultrafine particles (diameter < 100 nm) may be important in the health effects of air pollution, in part because of their predicted high respiratory deposition. However, there are few measurements of ultrafine particle deposition during spontaneous breathing. The fractional deposition for the total respiratory tract o...

journal_title：Inhalation toxicology

authors： Daigle CC,Chalupa DC,Gibb FR,Morrow PE,Oberdörster G,Utell MJ,Frampton MW

更新日期：2003-05-01 00:00:00

abstract：:Most current deterministic computer dosimetry models use idealized dichotomous symmetrical infant, child, and adolescent tracheobronchial geometries for dosimetry predictions. These tracheobronchial geometries were derived from either the morphometric measurements of J. D. Mortensen and colleagues or those of R. F. Ph...

journal_title：Inhalation toxicology

authors： Oldham MJ,Robinson RJ

更新日期：2006-09-01 00:00:00

abstract：:Recurrent events, such as repeated hospital admissions for the same health outcome, occur frequently in environmental health studies. In this study, we conducted an analysis of data on repeated respiratory hospitalizations among the elderly in Vancouver, Canada, for the period of June 1, 1995, to March 31, 1999, using...

journal_title：Inhalation toxicology

authors： Fung KY,Khan S,Krewski D,Chen Y

更新日期：2006-12-01 00:00:00

abstract：:Recent studies have shown that air pollution is a risk factor for hospitalization for pneumonia. However, there is limited evidence to suggest what subpopulations are at greater risk from air pollution. This study was undertaken to examine the modifying effect of specific secondary diagnosis (including hypertension, d...

journal_title：Inhalation toxicology

authors： Cheng MF,Tsai SS,Chiu HF,Sung FC,Wu TN,Yang CY

更新日期：2009-11-01 00:00:00

abstract：:Pulmonary tissue injury and repair processes involve complex and coordinated cellular events such as necrosis, inflammation, cell growth/differentiation, apoptosis, and remodeling of extracellular matrix. These processes are regulated by expression of multiple mediator genes. Commercially available microarray blots an...

journal_title：Inhalation toxicology

authors： Nadadur SS,Schladweiler MC,Kodavanti UP

更新日期：2000-12-01 00:00:00

abstract：:An approach to identify causal components of complex air pollution mixtures was explored. Rats and mice were exposed by inhalation 6 h daily for 1 week or 6 months to dilutions of simulated downwind coal emissions, diesel and gasoline exhausts and wood smoke. Organ weights, hematology, serum chemistry, bronchoalveolar...

journal_title：Inhalation toxicology

authors： Mauderly JL,Seilkop SK

更新日期：2014-09-01 00:00:00

abstract：:Epidemiological studies of particulate matter (PM) using central area monitors have associated total PM mass, as well as certain individual components of PM, including sulfate, with adverse human health effects. However, some recent studies that used concentrated ambient particles (CAPs) or analyzed the effects of air...

journal_title：Inhalation toxicology

authors： Grahame T,Schlesinger R

更新日期：2005-01-01 00:00:00

abstract：:The aim of this study was to investigate the potential cytotoxicity of solid lipid nanoparticles (SLN) loaded with sildenafil. The SLNs were tested as a new drug delivery system (DDS) for the inhalable treatment of pulmonary hypertension in human lungs. Solubility of sildenafil in SLN lipid matrix (30:70 phospholipid:...

journal_title：Inhalation toxicology

authors： Paranjpe M,Neuhaus V,Finke JH,Richter C,Gothsch T,Kwade A,Büttgenbach S,Braun A,Müller-Goymann CC

更新日期：2013-08-01 00:00:00