Autologous stromal vascular fraction cells: a tool for facilitating tolerance in rheumatic disease.

abstract：:C3H/HeJ mice are homozygous for the Lpsd allele and, as a consequence, are hyporesponsive to all of the biological effects of bacterial lipopolysaccharide (LPS) that have been studied. These mice die in the early phase of infection when inoculated with virulent Salmonella. This susceptibility is also regulated by the ...

journal_title：Cellular immunology

authors： Weinstein DL,Lissner CR,Swanson RN,O'Brien AD

更新日期：1986-10-01 00:00:00

abstract：OBJECTIVE:Many CD95-expressing cells don't always undergo apoptosis after stimulation with CD95 ligation. The purpose of this paper is to investigate the role of expression of CD95 (Fas/Apo1) on inflammatory response in fibroblast-like synoviocytes (FLS) obtained from rheumatoid arthritis (RA) and to evaluate the role ...

journal_title：Cellular immunology

authors： Li X,Zhang Z,Peng A,He M,Xu J,Shen S,Zhuang J,Huang X

更新日期：2014-08-01 00:00:00

abstract：:This study aimed to describe the vascular and cellular histopathological changes that occurred in post-mastectomy seroma in an animal model. Unilateral mastectomies were conducted on 45 female albino rabbits. On day seven, the skin flap and the underlying tissues of the mastectomy regions were dissected and processed ...

journal_title：Cellular immunology

authors： Al-Gaithy ZK,Ayuob NN

更新日期：2012-01-01 00:00:00

abstract：:Psychological stress evokes rapid changes to the cardiovascular and neuroendocrine systems, responses that can become habituated following repeated exposure. This study, comprising of two phases, suggests that the immune system follows a similar trend. Phase 1: 15 healthy subjects (aged between 26 and 56years) provide...

journal_title：Cellular immunology

authors： Shelton-Rayner GK,Macdonald DW,Chandler S,Robertson D,Mian R

更新日期：2010-01-01 00:00:00

abstract：:The glycobiology of the immune response is a topic that has garnered increased attention due to a number of key discoveries surrounding IgG function, the specificity of some broadly neutralizing anti-HIV antibodies, cancer immunoregulation by galectin molecules and others. This review is the opening article in a Speci...

journal_title：Cellular immunology

authors： Oswald DM,Cobb BA

更新日期：2018-11-01 00:00:00

abstract：:Previous work in our laboratory established that individual complement components can be regulated in vivo by administration of specific antibody or immunocompetent cells to newborns and in vitro by administration of specific antibody to cultured peritoneal macrophages or splenic fragments. Antibody-induced suppressio...

journal_title：Cellular immunology

authors： Goldman JN,O'Rourke KS,Goldman MB

更新日期：1985-11-01 00:00:00

abstract：:In this paper, we examined the contribution of the lymphokine interleukin-6 (IL-6) to the growth of four virulent strains of Mycobacterium avium and the nature of the binding moieties on the mycobacteria. First, we showed that human or mouse recombinant interleukin-6 are potent growth factors for four strains of virul...

journal_title：Cellular immunology

authors： Denis M

更新日期：1992-04-15 00:00:00

abstract：:The pre-B cell stage of B lymphocyte development is characterized by the presence of immunoglobulin heavy chains of the IgM isotype in the cytoplasm and no other heavy or light chains in the cytoplasm or on the surface. We established several cell lines that were identical in their serologically defined pre-B cell phe...

journal_title：Cellular immunology

authors： Griffin JA,Spalding DM

更新日期：1989-04-01 00:00:00

abstract：:Plasmacytoid dendritic cells (PDCs) from human umbilical cord blood (UCB) produce lower amounts of IFN-α upon TLR stimulation compared with adult counterparts. This difference may play a role in the low graft-versus-host disease rate after UCB transplantation and in the impaired immune response of the neonate to patho...

journal_title：Cellular immunology

authors： Charrier E,Cordeiro P,Cordeau M,Dardari R,Michaud A,Harnois M,Merindol N,Herblot S,Duval M

更新日期：2012-03-01 00:00:00

abstract：:Mice were infected with Plasmodium (P.) yoelii blood-stage parasites. Both the liver and spleen were the sites of inflammation during malarial infection at the beginning of day 7. The major expanding cells were found to be NK1.1(-) intermediate alphabetaTCR (alphabetaTCR(int)) in the liver and spleen, although the pop...

journal_title：Cellular immunology

authors： Weerasinghe A,Sekikawa H,Watanabe H,Mannoor K,Morshed SR,Halder RC,Kawamura T,Kosaka T,Miyaji C,Kawamura H,Seki S,Abo T

更新日期：2001-01-10 00:00:00

abstract：:Numerous reports in the literature describe the effects of beta-adrenergic agonists and/or their second messenger cyclic AMP on in vitro and in vivo immune responses. The fact that the murine spleen receives rich adrenergic innervation and that the pharmacologic disruption of this innervation leads to altered immune r...

journal_title：Cellular immunology

authors： Fuchs BA,Campbell KS,Munson AE

更新日期：1988-12-01 00:00:00

abstract：:Spontaneously cytotoxic cells possessing specificity and having a complex pattern of reactivity directed at least partly against self-determinants develop by the age of 10 weeks in the autoimmune mouse strain MRL/Mp-lpr/lpr (MRL-lpr) and by the age of 6 months in C57BL/6-lprl/lpr. Similar effector cells do not develop...

journal_title：Cellular immunology

authors： Muraoka S,Miller RG

更新日期：1988-04-15 00:00:00

abstract：:Hen egg white lysozyme (HEL)-specific T cell lines and clones were generated from B6 and BDF1 mice. A variety of clonotypes were found among clones generated at an early stage (1 month) whereas fewer clonotypes were detected after several weeks of culture. Furthermore, a bulk line switched from its initial fine peptid...

journal_title：Cellular immunology

authors： Manca F,Dessí V,Shastri N,Oki A,Kaplan M,Clarke J,Miller A,Sercarz EE

更新日期：1994-04-01 00:00:00

abstract：:Medicinal plants are considered immunomodulatory as they display various biological activities. There is no report addressing the anti-inflammatory effects of Daphne gnidium. In this study, we investigated the effects of D. gnidium ethyl acetate (EA) leaf extract on mice immune cell function in vitro. Production of pr...

journal_title：Cellular immunology

authors： Harizi H,Chaabane F,Ghedira K,Chekir-Ghedira L

更新日期：2011-01-01 00:00:00

abstract：:Intravital imaging of cutaneous immune responses has revealed intricate links between the skin's structural properties, the immune cells that reside therein, and the carefully orchestrated migratory dynamics that enable rapid sensing and subsequent elimination of skin pathogens. In particular, the development of 2-pho...

journal_title：Cellular immunology

authors： Zaid A

更新日期：2020-04-01 00:00:00

abstract：:Twenty-seven different CD45 monoclonal antibodies (mAb) were assessed for their ability to block cytotoxicity of alloreactive CD4+ MHC class II-specific or CD8+ class I-specific human T cell clones (n = 3 and 5, respectively). Twelve of 27 blocked the former but only 1/27 the latter, although all 27 significantly inhi...

journal_title：Cellular immunology

authors： Pawelec G,Bühring HJ,Müller C

更新日期：1990-05-01 00:00:00

abstract：:Macrophages are key cell types of innate immunity and play a central role in inflammation and host defense. Leukocyte-associated Ig-like receptor-1 (LAIR-1) is highly expressed on macrophages and regulates macrophage functions in several conditions. However, whether LAIR-1 is involved in governing macrophage polarizat...

journal_title：Cellular immunology

authors： Jin J,Wang Y,Ma Q,Wang N,Guo W,Jin B,Fang L,Chen L

更新日期：2018-09-01 00:00:00

abstract：:The mechanism of suppression of experimental allergic encephalomyelitis (EAE) induced in Lewis rats by pretreatment with myelin basic protein (MBP) coupled to syngeneic spleen leukocytes (SL) was examined. Studies on the kinetics of the tolerance induction showed that pretreatment with MBP-SL suppressed EAE if given 7...

journal_title：Cellular immunology

authors： McKenna RM,Carter BG,Sehon AH

更新日期：1984-10-15 00:00:00

abstract：:Monolayers of freshly isolated human monocytes are known to ingest particulate activators of the human alternative complement pathway. The ingestion of rabbit erythrocytes, ER, by human monocytes in serum-free medium was studied. The process is Mg2+-dependent and optimum phagocytic activity was obtained at approximate...

journal_title：Cellular immunology

authors： Chakravarti B

更新日期：1988-05-01 00:00:00

abstract：:Evidence is presented that rat serosal mast cells and cells of the rat basophilic leukemia line, RBL-1, each contain a calcium-activated, phospholipid-dependent protein kinase. The enzymes are very similar in their activation requirements to the calcium-dependent enzymes termed protein kinase Cs in brain. The enzyme i...

journal_title：Cellular immunology

authors： Kurosawa M,Parker CW

更新日期：1986-12-01 00:00:00

abstract：:The effect of low-dose irradiation on the immune system was investigated in mice. When a 0.2 Gy dose of X-ray irradiation was administered every other day for a total of four times, the number of lymphocytes yielded by the liver, spleen and thymus decreased at the initial stage (around day 10). At this stage, NK cells...

journal_title：Cellular immunology

authors： Ren H,Shen J,Tomiyama-Miyaji C,Watanabe M,Kainuma E,Inoue M,Kuwano Y,Abo T

更新日期：2006-11-01 00:00:00

abstract：:We have addressed the differential regulatory properties that IFN-gamma and IL-4 exert on macrophage (M phi) subpopulations. For this purpose, Thyoglicolate-, Peptone-, and Con A-elicited M phi, as well as bone marrow-derived M phi and P388D1 cells, were cultured in the presence of either IFN-gamma or IL-4. The expres...

journal_title：Cellular immunology

authors： Molina IJ,Huber BT

更新日期：1991-04-15 00:00:00

abstract：:A recombinant form of human soluble CD23 (sCD23), the low affinity receptor for IgE (FcepsilonRII), was produced by PCR cloning the lectin-binding domain sequence into a bacterial expression vector. After renaturation and purification, the sCD23 bound IgE and divalent metal ions, indicating its activity. The recombina...

journal_title：Cellular immunology

authors： Daniels BB,Askew SL,van de Venter M,Oosthuizen V

更新日期：2005-04-01 00:00:00

abstract：:PD-1 is an immunoregulatory receptor expressed on the surface of activated T cells, B cells, and monocytes. We describe four alternatively spliced PD-1 mRNA transcripts (PD-1Deltaex2, PD-1Deltaex3, PD-1Deltaex2,3, and PD-1Deltaex2,3,4) in addition to the full length isoform. PD-1Deltaex2 and PD-1Deltaex3 are generated...

journal_title：Cellular immunology

authors： Nielsen C,Ohm-Laursen L,Barington T,Husby S,Lillevang ST

更新日期：2005-06-01 00:00:00

abstract：:CD48, the murine homolog of human CD58, binds to CD2 in rats and mice. Whereas inhibition of CD2 signaling leads to profound immunosuppression, no information is available on CD48-targeted therapy in the rat. We could show that anti-CD2 treatment (OX34) efficiently inhibited TCR-driven as well as CD2-mediated prolifer...

journal_title：Cellular immunology

authors： Sido B,Otto G,Zimmermann R,Müller P,Meuer SC,Dengler TJ

更新日期：1997-11-25 00:00:00

abstract：:Human K cells are able to lyse human lymphoblastoid B cells in the presence of specific anti-human immunoglobulin isotype antibodies. The human lymphoblastoid B-cell line DAUDI (surface mu- and kappa-chains positive) was lysed in the presence of anti-mu and anti-kappa antisera, or IgG fraction of these antisera, and B...

journal_title：Cellular immunology

authors： Caraux J,Weigle WO

更新日期：1983-03-01 00:00:00

abstract：:The in vitro effect of single or combined doses of zidovudine (AZT) and dideoxycytidine (ddC) on the production and utilization of interleukin-2 (IL-2) by normal human peripheral blood mononuclear cells (PBMC) was evaluated by measuring IL-2 concentrations in supernatants from PHA-stimulated PBMC cultures. Drugs were ...

journal_title：Cellular immunology

authors： Viora M,Camponeschi B

更新日期：1995-07-01 00:00:00

abstract：:This report compares the ability of cyclosporin A and FK-506 to inhibit human T cell activation triggered via cell surface molecules that utilize different intracellular processes. We stimulated highly purified peripheral blood T lymphocytes with mitogens (Con A and PHA), ionomycin + PMA, or monoclonal antibodies spec...

journal_title：Cellular immunology

authors： Lin CS,Boltz RC,Siekierka JJ,Sigal NH

更新日期：1991-04-01 00:00:00

abstract：:Previous studies established that low in vitro temperatures (27 degrees C, termed nonpermissive) suppressed murine primary thymus-dependent (TD), but not primary thymus-independent (TI) or secondary TD, antibody responses. Suppression was rescued by the addition of oleic acid (18:1), recombinant interleukin (rIL)-2 an...

journal_title：Cellular immunology

authors： Wooten RM,Clem LW,Bly JE

更新日期：1993-11-01 00:00:00

abstract：:Autoimmune regulator (Aire) is a transcriptional activator that regulates the ectopic expression of many tissue-restricted antigens in medullary thymic epithelial cells, and that has an important role in the negative selection of autoreactive T cells. However, the roles of Aire expression in peripheral lymphoid tissue...

journal_title：Cellular immunology

authors： Zhu W,Yang W,He Z,Liao X,Wu J,Sun J,Yang Y,Li Y

更新日期：2011-01-01 00:00:00