Studies on phagocytosis of unopsonized rabbit erythrocytes by human monocytes.

abstract：:The induction of ornithine decarboxylase (ODC) activity in lymphocytes is associated with activation and the initiation of cellular proliferation. ODC is also an essential component in tumor promotion. Phorbol myristic acetate (PMA) is a mitogen for lymphocytes, but can also promote tumor formation. Tumor promotion is...

journal_title：Cellular immunology

authors： Fidelus RK

更新日期：1988-04-15 00:00:00

abstract：:T lymphocytes respond to mitogenic stimulation by expressing the receptor for interleukin 2 (Il-2) and secreting Il-2; once the receptor is expressed, Il-2 induces these cells to proliferation. In the present report using mouse T lymphocytes, thymocytes, and the lymphoma cell line EL4, we studied receptor expression a...

journal_title：Cellular immunology

authors： Truneh A,Simon P,Schmitt-Verhulst AM

更新日期：1986-12-01 00:00:00

abstract：:The susceptibility of murine embryonic cells to CTL lysis has been assessed. Zona-free blastocysts were not lysed during 6 hr incubation with CTL sensitized against the embryonic genotype and remained capable of implantation and normal development in vivo as well as outgrowth in vitro. Freshly dissociated cells from p...

journal_title：Cellular immunology

authors： Croy BA,Rossant J

更新日期：1987-02-01 00:00:00

abstract：:Macrophages are highly plastic immune cells with temporally distinct transcriptome changes upon lipopolysaccride (LPS) activation. However, to what extent transcriptome reprogramming is mediated via spatial chromatin looping is not well studied. We generated high resolution chromatin interaction maps for LPS-stimulate...

journal_title：Cellular immunology

authors： Pradhananga S,Spalinskas R,Poujade FA,Eriksson P,Sahlén P

更新日期：2020-09-01 00:00:00

abstract：:Sensitized T lymphocytes can mediate potent antitumor effects when transferred to tumor-bearing animals. Employing the MCA 105 and MCA 106 sarcomas, we were able to generate antitumor effector cells by immunization of syngeneic mice with tumor cells admixed with Corynebacterium parvum. These immune splenocytes could b...

journal_title：Cellular immunology

authors： Chang AE,Perry-Lalley DM,Shu S

更新日期：1989-05-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) have been used to repair injured tissues through immune-suppression and/or cell replace mechanisms. However, a significant barrier to MSC therapy is insufficient MSC engraftment in injured tissues after systemic administration. Here, we report that cell surface, total protein, and mRNA le...

journal_title：Cellular immunology

authors： Xie J,Wang W,Si JW,Miao XY,Li JC,Wang YC,Wang ZR,Ma J,Zhao XC,Li Z,Yi H,Han H

更新日期：2013-01-01 00:00:00

abstract：:Humans with autoimmune disease and autoimmune mouse strains such as NZB have been shown to produce reduced levels of the cytokines interleukin 1 and interleukin 2. The NZB X C58 recombinant inbred (N X 8 RI) strains exhibit certain of the autoimmune characteristics of the NZB strain. Their abilities to produce interle...

journal_title：Cellular immunology

authors： Bocchieri MH,Knittweis L,Seaton DS

更新日期：1984-10-15 00:00:00

abstract：:Ca(2+) and Sr(2+) entry pathways activated by pro-inflammatory agonists FMLP, LTB(4) and PAF have been compared to thapsigargin in human neutrophils. 2-APB (10microM) increased Ca(2+) influx and to a greater extent in agonist than in thapsigargin stimulated neutrophils. This action of 2-APB was specific to Ca(2+) beca...

journal_title：Cellular immunology

authors： Salmon MD,Ahluwalia J

更新日期：2010-01-01 00:00:00

abstract：:Transformed murine fetal thymocyte cell lines were derived by incubating fetal thymic organ cultures with a v-myc/v-raf-containing retroviral construct in order to model developmental stages within the early triple negative (CD3-CD4-CD8-) thymocyte population. The resulting 10 cell lines had a lymphoid morphology, wer...

journal_title：Cellular immunology

authors： Taubenberger JK,Reid AH,Izon D,Boehme SA

更新日期：1996-07-10 00:00:00

abstract：:The proliferative responses of natural killer (NK) cells to 12-O-tetradecanoylphorbol-13-acetate (TPA), which directly activates protein kinase c(PKC), and to the Ca2+ ionophores A23817 and ionomycin, known to enhance the intracellular calcium, have been investigated. Highly purified large granular lymphocytes (LGL) w...

journal_title：Cellular immunology

authors： Procopio A,Gismondi A,Paolini R,Morrone S,Testi R,Piccoli M,Frati L,Herberman RB,Santoni A

更新日期：1988-04-15 00:00:00

abstract：:We describe here a culture system for studying the development, in vitro, of antigen-specific CD4 T cells from unprimed mice. T cells from young mice are initially exposed to antigen, such as pigeon cytochrome C or keyhole limpet hemocyanin, in the presence of adherent accessory cells and then allowed to proliferate i...

journal_title：Cellular immunology

authors： Dozmorov I,Miller RA

更新日期：1997-06-15 00:00:00

abstract：:The effects of oral administration of ovalbumin (OVA) on acute OVA-induced arthritis (OIA) in rats, which is mediated by Arthus reaction to the antigen in the joint space, were investigated. The oral administration of OVA before immunization with OVA significantly suppressed the development of acute OIA in a dose-depe...

journal_title：Cellular immunology

authors： Inada S,Yoshino S,Haque MA,Ogata Y,Kohashi O

更新日期：1997-01-10 00:00:00

abstract：:Previous work has shown ICOS can function independently of CD28, but whether either molecule can compensate for the other in vivo is not known. Since ICOS is a potent inducer of Th2 cytokines and linked to allergy and elevated serum IgE in humans, we hypothesized that augmenting ICOS costimulation in murine allergic a...

journal_title：Cellular immunology

authors： Shilling RA,Clay BS,Tesciuba AG,Berry EL,Lu T,Moore TV,Bandukwala HS,Tong J,Weinstock JV,Flavell RA,Horan T,Yoshinaga SK,Welcher AA,Cannon JL,Sperling AI

更新日期：2009-01-01 00:00:00

abstract：:Idiotypic immunoglobulin, which can be considered to bear tumour-associated antigens in the context of B-cell lymphoma, has been obtained from the splenic A31 tumour, purified, and used to immunise syngeneic mice. On subsequent exposure to a lethal challenge of lymphoma cells, the mice showed no overt tumour developme...

journal_title：Cellular immunology

authors： Dyke RJ,McBride H,George AJ,Hamblin TJ,Stevenson FK

更新日期：1991-01-01 00:00:00

abstract：:To determine whether human antibody responses to T cell-independent pneumococcal polysaccharide antigens are derived from CD5+ or CD5- B cells, we utilized an ELISPOT assay to detect individual anti-polysaccharide antibody-secreting cells. Human anti-type IV pneumococcal polysaccharide antibody-secreting cells were fo...

journal_title：Cellular immunology

authors： Barrett DJ,Sleasman JW,Schatz DA,Steinitz M

更新日期：1992-08-01 00:00:00

abstract：:The knowledge of mechanisms of regulation of IL-10 production by B cells remains still very limited. We show here that highly purified mouse B cells stimulated with LPS produce significant levels of IL-10, but Bregs in our model do not express detectable level of either Foxp3 or GATA-3. Nevertheless, IL-10 production ...

journal_title：Cellular immunology

authors： Bohacova P,Kossl J,Hajkova M,Hermankova B,Javorkova E,Zajicova A,Krulova M,Holan V

更新日期：2020-01-01 00:00:00

abstract：:In vitro incubations of CD4+ T cells with anti-CD4 monoclonal antibody (Mab) demonstrated saturation binding and inhibited both PPD-stimulated proliferation and delayed-type hypersensitivity (DTH) after passive transfer of these cells into naive rats. In comparison, in vivo administration of anti-CD4 Mab into rats, 2 ...

journal_title：Cellular immunology

authors： Morrison WJ,Kennedy NJ,Offner H,Vandenbark AA

更新日期：1995-06-01 00:00:00

abstract：:In this study, skin-infiltrating cells were prepared from guinea pig delayed-type hypersensitivity reaction sites, and their phenotypic properties and cytokine production were examined. Our cell preparations contained around 45% nonspecific esterase-positive cells and a few skin-derived cells. Skin-infiltrating cells ...

journal_title：Cellular immunology

authors： Higashi N,Yoshizuka N,Kobayashi Y

更新日期：1995-08-01 00:00:00

abstract：:Controversies remain about NK cells direct responsiveness to Toll-like receptor (TLR) agonists or dependence on macrophages. In a melanoma lung metastasis model, aerosolized TLR9 and TLR3 agonists have been reported to induce antitumor immunity through NK cells activation. In the current study, we demonstrated that in...

journal_title：Cellular immunology

authors： Sommariva M,Le Noci V,Storti C,Bianchi F,Tagliabue E,Balsari A,Sfondrini L

更新日期：2017-03-01 00:00:00

abstract：:We previously demonstrated that injection of a high dose (4 X 10(9] of sheep erythrocytes (SRBC) into C57BL/6 mice results in the generation of splenic B cells (plastic nonadherent, Thy-1- and Ig+) which, when transferred to normal syngeneic recipients, subsequently induce antigen-specific suppressor T cells to suppre...

journal_title：Cellular immunology

authors： Shimamura T,Habu S,Hashimoto K,Sasaki S

更新日期：1984-01-01 00:00:00

abstract：:The purpose of this study was to determine whether multiple types of suppressor factors play a role in the regulation of immune responses by ultraviolet radiation-induced suppressor T lymphocytes (UV Ts). The UV Ts were induced by applying contact allergens to the ventral, unirradiated skin of mice exposed 5 days earl...

journal_title：Cellular immunology

authors： Yee GK,Ullrich SE,Kripke ML

更新日期：1989-06-01 00:00:00

abstract：:Poxviruses are a large, complex group of highly successful pathogens that cause disease in humans and other animals. They encode several proteins postulated to be involved in the evasion of host immunity and therefore serve as excellent models for understanding virus-host interaction during the early stages of viral i...

journal_title：Cellular immunology

authors： Miller CG,Justus DE,Jayaraman S,Kotwal GJ

更新日期：1995-05-01 00:00:00

abstract：:We report experiments attempting to optimize the proliferative response of human B cells to rabbit anti-immunoglobulin antibody (RAHIg)-linked beads (anti-Ig beads). By choosing polyacrylamide beads of small size (3 micron) and coupling anti-Ig to them at high concentrations, beads were obtained which were both B-cell...

journal_title：Cellular immunology

authors： Boyd AW,Freedman AS,Horowitz JC,Anderson KC,Fisher DC,Rosen KJ,Schlossman SF,Nadler LM

更新日期：1986-04-15 00:00:00

abstract：:The primary function of the thymus is to develop immature T-cells into cells that further in the periphery will be able to carry out immune functions. The Literature has shown that thymus can be a target for many pathogens and severe structural alterations take place in this organ during infectious diseases. Here, we ...

journal_title：Cellular immunology

authors： Andrade CF,Gameiro J,Nagib PR,Carvalho BO,Talaisys RL,Costa FT,Verinaud L

更新日期：2008-05-01 00:00:00

abstract：:The morbidity and mortality of infectious diseases are significantly increased in aged humans. Hence, vaccination has been suggested as a means to reduce or prevent the impact of infections on old individuals. However, it has remained unresolved whether or not standard vaccine adjuvants such as aluminum hydroxide (Alu...

journal_title：Cellular immunology

authors： Ebhardt MB,Shive CL,Guardia R,Gapin L,Boehm BO,Forsthuber TG

更新日期：2002-01-01 00:00:00

abstract：:Castration of normal male mice leads to splenic enlargement and expansion of the B cell population. Since the spleen does not express receptors for androgens, these changes are most likely mediated by effects of androgens on other target organs. Two potential sites of androgen-mediated effects on B cells are evaluated...

journal_title：Cellular immunology

authors： Viselli SM,Reese KR,Fan J,Kovacs WJ,Olsen NJ

更新日期：1997-12-15 00:00:00

abstract：:We compared macrophage binding and killing of F5b cells to the binding and killing of P815 mastocytoma cells and to several other nontransformed and transformed cell lines. Formalin fixation of elicited or activated macrophages did not affect binding of F5b or 3T3 cells but did abrogate binding of P815 cells. However,...

journal_title：Cellular immunology

authors： Rosenkrans CF Jr,Chapes SK

更新日期：1991-03-01 00:00:00

abstract：:T cell hybridomas that are deathless upon TCR crosslinking were generated from lpr mice. The deathless hybridomas (1.4 and 5D5) expressed extremely low Fas even after anti-CD3 activation, whereas activation-induced cell death (AICD) was observed for Fas-expressing hybridomas. The deathless hybridomas were activated to...

journal_title：Cellular immunology

authors： Cui H,el-Khatib M,Sherr DH,Ettinger R,Sy MS,Marshak-Rothstein A,Ju ST

更新日期：1996-02-01 00:00:00

abstract：:Theiler's murine encephalomyelitis virus-induced demyelinating disease (TMEV-IDD), a model for multiple sclerosis, is a chronic T cell-mediated disease. Development of clinical symptoms in susceptible mouse strains generally correlates with TMEV-specific delayed-type hypersensitivity (DTH) responses. These responses, ...

journal_title：Cellular immunology

authors： Pelka A,Olsberg C,Miller S,Waltenbaugh C,Creighton TM,dal Canto MC,Melvold R

更新日期：1993-12-01 00:00:00

abstract：:Optical imaging is a valuable tool to visualise biological processes in the context of the tissue. Each imaging modality provides the biologist with different types of information - cell dynamics and migration over time can be tracked with time-lapse imaging (e.g. intra-vital imaging); an overview of whole tissues can...

journal_title：Cellular immunology

authors： Husna N,Gascoigne NRJ,Tey HL,Ng LG,Tan Y

更新日期：2019-10-01 00:00:00