Abstract：
:La France disease of the cultivated mushroom, Agaricus bisporus, is known to be associated with the presence of a number of dsRNA segments. The nucleotide sequences of the dsRNAs M2 (1.3 kb), M1 (1.55 kb) and L3 (2.8 kb), invariably associated with the disease, were determined. Putative coding sequences for proteins with molecular weights of 38, 40 and 87 kDa were found for M2, M1 and L3 dsRNAs, respectively. The average G + C content of these dsRNAs was 43%, close to that of A. bisporus nuclear DNA. The nucleotide sequences, as well as the amino acid sequences, appear to be unique, as no matching sequences could be found among databases. S3 dsRNA (0.39 kb), which is occasionally found in large amounts in diseased mushrooms, is an internally deleted variant of M2 dsRNA and is largely composed of the non-coding ends of that dsRNA.
journal_name
Curr Genetjournal_title
Current geneticsauthors
Harmsen MC,Tolner B,Kram A,Go SJ,de Haan A,Wessels JGdoi
10.1007/BF00312776subject
Has Abstractpub_date
1991-07-01 00:00:00pages
137-44issue
1-2eissn
0172-8083issn
1432-0983journal_volume
20pub_type
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