Abstract:
:Blasticidin S-resistant mutants of S. cerevisiae were isolated and characterized. Resistant mutations were found to fall into two complementation groups. A single recessive nuclear gene was responsible for each group, donated as bls1 and bls2, respectively. A gene bls1 was linked to an ilv3 gene located on the right arm of chromosome X. The resistant phenotypes from both genes were not associated with ribosomes known to be target sites of Blasticidin S, when analyzed by poly(U)-directed polyphenylalanine synthesis. The resistant mechanisms of the mutations are discussed in this paper.
journal_name
Curr Genetjournal_title
Current geneticsauthors
Ishiguro J,Miyazaki Mdoi
10.1007/BF00436968subject
Has Abstractpub_date
1985-01-01 00:00:00pages
179-81issue
2eissn
0172-8083issn
1432-0983journal_volume
9pub_type
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