Abstract:
:A Neurospora crassa cytoplasmic ribosomal protein gene, crp-5, has been isolated and characterized. The cDNA was isolated by a differential screening of a cDNA library for glucose-inducible genes. The cDNA was subsequently used to identify and isolate crp-5 genomic sequences. Computer analysis of the DNA sequences showed that they contain an open reading frame which encodes a protein homologous to the rat ribosomal protein S26. The crp-5 mRNA levels are regulated in a carbon-source-dependent manner. The organization of the gene and the region upstream of the coding sequences are discussed.
journal_name
Curr Genetjournal_title
Current geneticsauthors
Wang Z,Tarawneh KA,Free SJdoi
10.1007/BF00310894subject
Has Abstractpub_date
1993-01-01 00:00:00pages
330-3issue
4eissn
0172-8083issn
1432-0983journal_volume
23pub_type
杂志文章相关文献
CURRENT GENETICS文献大全abstract::Laccases are phenol-oxidizing, multicopper enzymes produced by fungi, plants, insects and bacteria. Fungal laccases are involved in ecologically important processes such as decomposition of lignocellulose (wood and plant material). In this work, in order to find out the role of fungal laccases upon wood colonisation a...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/s00294-006-0090-1
更新日期:2006-11-01 00:00:00
abstract::Retrotransposons are activated as organisms age, based on work from several model systems. Since these mobile DNA elements can promote genome instability, this has raised the possibility that they can contribute to loss of cellular function with age. Many questions remain to be addressed about the relationship between...
journal_title:Current genetics
pub_type: 杂志文章,评审
doi:10.1007/s00294-015-0538-2
更新日期:2016-05-01 00:00:00
abstract::In eukaryotes, the ubiquitin-like (UBL) protein-activating enzymes play a crucial role in autophagy process, however, it is poorly characterized in filamentous fungi. Here, we investigated the functions of two UBL activating enzymes, BcAtg3 (E2) and BcAtg7 (E1) in the plant pathogenic fungus Botrytis cinerea. The phys...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/s00294-018-0810-3
更新日期:2018-08-01 00:00:00
abstract::We have constructed a gene coding for the 12-kDa intermediate form of the 2s methionine-rich protein from Bertholletia excelsa seeds. This protein, expressed intracellularly in yeast, is characterised by a 20-min half-life. By adding 11 amino acids corresponding to the peroxisome-targeting sequence (PTSc) of luciferas...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF00309924
更新日期:1994-11-01 00:00:00
abstract::In Chlamydomonas reinhardtii, the expression of the nit1 gene encoding nitrate reductase is dependent on the nature of the nitrogen source and on other environmental factors. We have fused the nit1 promoter region to the arylsulphatase (ars) reporter gene lacking its own promoter and introduced this chimeric construct...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/s002940050204
更新日期:1997-03-01 00:00:00
abstract::Primary transcripts in higher plant cell organelles undergo a series of essential RNA processing steps, including 5'- and 3'-terminal maturation, intron splicing and RNA editing. Most of the protein factors involved in these RNA processing mechanisms are still unknown. Also, little is known about the environmental and...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/s00294-002-0278-y
更新日期:2002-04-01 00:00:00
abstract::We describe the preparation of an in vitro translation system from heat shock-treated Aspergillus nidulans, capable of supporting efficient and faithful synthesis of proteins from natural and in vitro transcribed eukaryotic messages. In vitro synthesized prepro-alpha-factor was translocated across Aspergillus nidulans...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF00434081
更新日期:1988-12-01 00:00:00
abstract::Caffeine is a well known base analogue and is cytotoxic to both animal and yeast cells. There are two possible mechanisms by which yeast cells tolerate caffeine concentrations higher than normal, by mutation or by physiological adaptation. We have isolated novel caffeine-resistant mutants of S. pombe which define thre...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/s002940050233
更新日期:1997-06-01 00:00:00
abstract::Degenerative processes in the filamentous fungus Podospora anserina are strongly correlated with the instability of the mitochondrial genome. Among the sources of instability is the mobile group-II intron COX1-i1, also called intron alpha, which encodes a protein with a reverse transcriptase activity. In this paper we...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/s002940050003
更新日期:2000-01-01 00:00:00
abstract::The S. cerevisiae strain h56 is a temperature-sensitive mit- mutant containing a single nucleotide substitution in the region 5' to the reading frame of the mitochondrial var1 gene. The mutation decreases the efficiency of processing of a precursor RNA such that little var1 mRNA is produced at the restrictive temperat...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF00357168
更新日期:1994-03-01 00:00:00
abstract::Cells divide with appropriate frequency by coupling division to growth-that is, cells divide only when they have grown sufficiently large. This process is poorly understood, but has been studied using cell size mutants. In principle, mutations affecting cell size could affect the mean size ("set-point" mutants), or th...
journal_title:Current genetics
pub_type: 杂志文章,评审
doi:10.1007/s00294-020-01098-4
更新日期:2020-11-05 00:00:00
abstract::Replication-coupled (RC) nucleosome assembly is an essential process in eukaryotic cells to maintain chromatin structure during DNA replication. The deposition of newly-synthesized H3/H4 histones during DNA replication is facilitated by specialized histone chaperones. CAF-1 is an important histone chaperone complex an...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/s00294-020-01113-8
更新日期:2020-10-06 00:00:00
abstract::Stress granules (SGs) are evolutionarily conserved ribonucleoprotein (RNP) structures that form in response to a variety of environmental and cellular cues. The presence of these RNP granules has been linked to a number of human diseases, including neurodegenerative disorders like amyotrophic lateral sclerosis (ALS) a...
journal_title:Current genetics
pub_type: 杂志文章,评审
doi:10.1007/s00294-016-0571-9
更新日期:2016-08-01 00:00:00
abstract::Single-strand breaks (SSB) are discontinuities in one strand of the DNA double helix and are the most common type of damages that arise in cells. SSBs arise mainly from direct attack by intracellular metabolites, however, also essential nuclear processes generate SSBs as intermediates. During the catalytic cycle of DN...
journal_title:Current genetics
pub_type: 杂志文章,评审
doi:10.1007/s00294-019-00984-w
更新日期:2019-10-01 00:00:00
abstract::In the fungus Fusarium sporotrichioides, biosynthesis of trichothecene mycotoxins requires at least three genetic loci: a core 12-gene cluster, a smaller two-gene cluster, and a single-gene locus. Here, we describe the Tri15 gene, which represents a fourth locus involved in trichothecene biosynthesis. Tri15 is predict...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/s00294-003-0467-3
更新日期:2004-03-01 00:00:00
abstract::We have cloned and sequenced human and bovine cDNAs for the beta subunit of the ATP synthase (ATP-syn beta), a nuclear DNA (nDNA) encoded oxidative phosphorylation (OXPHOS) gene. The two cDNAs were found to share 99% amino acid homology and 94% nucleotide homology. The evolutionary rate of ATPsyn beta was then compare...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF00434661
更新日期:1987-01-01 00:00:00
abstract::Group-I introns, containing open reading frames (ORFs) that code for homing endonucleases, are widely distributed amongst eukaryotic organellar genomes. However, endonucleases of the GIY-YIG subclass have a restricted distribution in mitochondria and bacteriophages, and have never been observed in plastids. We have fo...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF00311888
更新日期:1995-06-01 00:00:00
abstract::A phylogenetic investigation of the autosporic chlorophycean alga species Selenastrum capricornutum using the small subunit (SSU) rRNA gene revealed the unusual presence of six group IC1 introns. Previous studies showed that numerous green algal taxa contain group IC1 introns. However, whereas some algal species harbo...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/s00294-004-0525-5
更新日期:2004-10-01 00:00:00
abstract::The A-pathway of development in the basidiomycete fungus Schizophyllum commune may be activated by either of two mating-type loci, A alpha and A beta. A alpha consists of two multiallelic genes, Y and Z. Y contains a putative homeodomain; Z contains a homeodomain-related region. Non-self combinations of Y and Z form h...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF02221577
更新日期:1996-01-01 00:00:00
abstract::Extraction of RNA from Tetrahymena mitochondrial ribosomes yields several RNA species, including a "large" 21S molecule, a "small" 14S molecule, a 7S molecule, and other smaller RNAs. The molecular weight of the 14S rRNA indicates that it is about 1,300 bases in length. We have sequenced the 14S rRNA gene and, by alig...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF00384616
更新日期:1987-01-01 00:00:00
abstract::ERG24 is the structural gene for the C14-sterol reductase in yeast. A lack of activity in that enzyme, mediated either by the morpholine fungicides or the insertional inactivation of ERG24, causes the accumulation of the aberrant sterol ignosterol. Cells producing this sterol are unable to grow aerobically in the rout...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/s002940050371
更新日期:1998-08-01 00:00:00
abstract::Small insertions are reported from the SSU rDNA of the genera Cladonia, Cladina, Stereocaulon, Pertusaria and Physcia (lichen-forming Lecanorales, Ascomycetes). The insertions range in length from 56 to 81 nucleotides, and occur at a shared position, 330 (relative to Escherichia coli), in a semi-conserved region of th...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/s002940050317
更新日期:1998-02-01 00:00:00
abstract::Sexual reproduction in Agrocybe aegerita is controlled by the tetrapolar mechanism of homogenic incompatibility. The two mating factors, A and B, are nonequivalent and exhibit functional specificity. Fourteen distinct A factors and 17 distinct B factors were identified in 17 natural isolates from Europe and Japan. ...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF00445743
更新日期:1982-05-01 00:00:00
abstract::This paper reports the mapping of both mature and precursor Paracentrotus lividus mitochondrial transcripts. Several mtRNAs were found to have 5' and 3' termini which differ from those inferred through DNA sequencing (Cantatore et al. 1989). The 3' ends of the two rRNAs (12S and 16S) overlap with the downstream transc...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF00312615
更新日期:1990-03-01 00:00:00
abstract::There are at least ten plant diseases caused by Alternaria species in which host-specific toxins (HSTs) are responsible for fungal pathogenicity. Of these HST-producers, seven are considered distinct pathotypes of the species Alternaria alternata, and the remaining three are among other species of pathogenic Alternari...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/s002940050464
更新日期:1999-07-01 00:00:00
abstract::Glutathione (GSH) is an abundantly produced low-molecular-weight (LMW) thiol in many organisms. However, a number of Gram-positive bacteria do not produce GSH, but instead produce bacillithiol (BSH) as one of the major LMW thiols. Similar to GSH, studies have found that BSH has various roles in the cell, including pro...
journal_title:Current genetics
pub_type: 杂志文章,评审
doi:10.1007/s00294-015-0511-0
更新日期:2016-02-01 00:00:00
abstract::In biological systems, reactive oxygen species (ROS) represent 'double edged swords': as signaling molecules they are essential for proper development, as reactive agents they cause molecular damage and adverse effects like degeneration and aging. A well-coordinated control of ROS is therefore of key importance. Super...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/s00294-014-0446-x
更新日期:2015-02-01 00:00:00
abstract::Genetic analysis of carotenogenesis in Phycomyces is hampered by the inability of most mutants to complete the sexual cycle. Heterokaryons between complementing mutants or between a mutant and a helper strain are, however, fertile. Using this method crosses have been carried out between mutants representing the differ...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF00445733
更新日期:1982-05-01 00:00:00
abstract::By completing and correcting the sequence of a 1.8 kb DNA segment downstream of the oxi2 gene of Saccharomyces cerevisiae, a long, potentially coding sequence ("RF2") has been identified. The sequence is rather closely related to the RF1 open reading frame, downstream of the oxil gene, and, further, to the major famil...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF00419729
更新日期:1984-05-01 00:00:00
abstract::DNA polymerases are evolved to extend the 3'-OH of a growing primer annealed to a template DNA substrate. Since replicative DNA polymerases have a limited role while replicating structurally distorted template, translesion DNA polymerases mostly from Y-family come to the rescue of stalled replication fork and maintain...
journal_title:Current genetics
pub_type: 杂志文章,评审
doi:10.1007/s00294-018-0918-5
更新日期:2019-06-01 00:00:00