Abstract:
:Genetic analysis of carotenogenesis in Phycomyces is hampered by the inability of most mutants to complete the sexual cycle. Heterokaryons between complementing mutants or between a mutant and a helper strain are, however, fertile. Using this method crosses have been carried out between mutants representing the different known genes and phenotypes.The gene for phytoene dehydrogenase, carB, is closely linked to carRA, a bifunctional gene specifying both lycopene cyclase and a product involved in substrate transfer. The regulatory gene carS lies on the same chromosome, but not close to the structural genes. The situation is thus reminiscent of an operon.Two chemoinsensitive mutants, showing little or no response to the effects of retinol and 2-(4-chlorophenyl)thiotriethylamine HCl on carotenogenesis, carry mutations in separate genes. One of these is probably identical with carRA; the other is a new gene termed carl.
journal_name
Curr Genetjournal_title
Current geneticsauthors
Roncero MI,Cerdá-Olmedo Edoi
10.1007/BF00445733subject
Has Abstractpub_date
1982-05-01 00:00:00pages
5-8issue
1eissn
0172-8083issn
1432-0983journal_volume
5pub_type
杂志文章相关文献
CURRENT GENETICS文献大全abstract::The cytoplasmic virus-like element pWR1A from Debaryomyces robertsiae encodes a toxin (DrT) with similarities to the Pichia acaciae killer toxin PaT, which acts by importing a toxin subunit (PaOrf2) with tRNA anticodon nuclease activity into target cells. As for PaT, loss of the tRNA methyltransferase Trm9 or overexpr...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/s00294-014-0426-1
更新日期:2014-08-01 00:00:00
abstract::Expression of pho1-encoded acid phosphatase of Schizosaccharomyces pombe has been reported to be regulated by phosphate. In this communication we show that it is also regulated by adenine. Starving adenine auxotrophic strains for adenine leads to a drastic increase of the enzymatic activity while adenine represses thi...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF00317923
更新日期:1992-10-01 00:00:00
abstract::A cluster of three tRNA genes located on fragment Bam6a from Vicia faba chloroplast DNA has been sequenced: it contains the genes for tRNA(CAALeu), tRNA(UAALeu) and tRNA(Phe). The two tRNA(Leu) genes are separated by 443 bp and are transcribed divergently from different DNA strands. The intergenic region contains a se...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF00421614
更新日期:1985-01-01 00:00:00
abstract::Although the mitochondrial genomes of the Chinese Spring and Aquila varieties of wheat are normally similar in organization, this is not so in tissue cultures initiated from their immature embryos where the mitochondrial genomes of both are rearranged and in different, characteristic, ways. However, the mitochondrial ...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF00351662
更新日期:1992-05-01 00:00:00
abstract::Spontaneous and double-strand break (DSB)-induced gene conversion in Saccharomyces cerevisiae was assayed using non-tandem chromosomal direct repeat crosses and plasmid x chromosome crosses. Each cross involved identical ura3 alleles marked with phenotypically silent restriction fragment length polymorphic (RFLP) muta...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/s002940050396
更新日期:1998-10-01 00:00:00
abstract::The nucleotide sequences of regions containing the mating-type locus of the plant-pathogenic ascomycete Leptosphaeria maculans are described. The MAT1-1 gene is 1,368 bp, encoding a predicted protein of 441 amino acids, with a 45-bp intron. The MAT1-2 gene is 1,246 bp, encoding a predicted protein of 397 amino acids, ...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/s00294-003-0391-6
更新日期:2003-08-01 00:00:00
abstract::In previous work, four genes involved in mating-type determination were cloned from reference strains of Pyrenopeziza brassicae; three genes, PAD1, PMT1, and PHB1 (re-named henceforth as MAT-1-1, MAT-1-4, and MAT1-3, respectively), are encoded by the MAT-1 idiomorph, and one gene, PHB2 (re-named MAT-2), by the corresp...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/s002940050503
更新日期:1999-11-01 00:00:00
abstract::The GGP1 gene encodes the only GPI-anchored glycoprotein (gp115) that has been purified to-date in the budding yeast Saccharomyces cerevisiae. It is a single-copy gene whose deduced amino-acid sequence shares no significant homology to any other known protein. In this paper we report a Southern hybridization analysis ...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF00336744
更新日期:1993-01-01 00:00:00
abstract::Retrotransposons are suitable targets for developing molecular markers for population genetics studies. Transposable elements have not yet been isolated from ectomycorrhizal fungi of the genus Tuber. In this paper, we report on the isolation and characterization of Tmt1, an LTR-retrotransposon from Tuber melanosporum....
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/s00294-007-0155-9
更新日期:2008-01-01 00:00:00
abstract::The A-pathway of development in the basidiomycete fungus Schizophyllum commune may be activated by either of two mating-type loci, A alpha and A beta. A alpha consists of two multiallelic genes, Y and Z. Y contains a putative homeodomain; Z contains a homeodomain-related region. Non-self combinations of Y and Z form h...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF02221577
更新日期:1996-01-01 00:00:00
abstract::A Neurospora crassa cytoplasmic ribosomal protein gene, crp-5, has been isolated and characterized. The cDNA was isolated by a differential screening of a cDNA library for glucose-inducible genes. The cDNA was subsequently used to identify and isolate crp-5 genomic sequences. Computer analysis of the DNA sequences sho...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF00310894
更新日期:1993-01-01 00:00:00
abstract::Gene expression using alternative transcription start sites (TSSs) is an important transcriptional regulatory mechanism for environmental responses in eukaryotes. Here, we identify two alternative TSSs in the enolase-encoding gene (enoA) in Aspergillus oryzae, an industrially important filamentous fungus. TSS use in e...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/s00294-020-01053-3
更新日期:2020-08-01 00:00:00
abstract::In yeast (S. cerevisiae) the stringent response is known to include rapid, selective, and severe transcriptional curtailment for genes specifying cytoplasmic rRNAs and r-proteins. We have shown that transcription of the mitochondrial 21S rRNA gene is also congruently and selectively curtailed during the yeast stringen...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF00336848
更新日期:1992-03-01 00:00:00
abstract::The single-copy nuclear gene (GapA), encoding the plastid-localized glyceraldehyde-3-phosphate dehydrogenase (GAPDH) of the marine red alga Gracilaria verrucosa, has been cloned and sequenced. The GapA transcriptional initiation site was located 49 bp upstream of the start codon, and a putative TATA box was found 54 b...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF00326308
更新日期:1994-07-01 00:00:00
abstract::International efforts are underway that aim at determining the complete genome sequence of the social amoeba Dictyostelium discoideum. As strategy, a whole chromosome shotgun (WCS) approach was chosen and each of the six Dictyostelium chromosomes was assigned to project partners. The project is well advanced, chromoso...
journal_title:Current genetics
pub_type: 杂志文章,评审
doi:10.1007/s00294-003-0416-1
更新日期:2003-11-01 00:00:00
abstract::Six ultra violet (UV) mutageneses were performed on the spo76 UV-sensitive mutant of Sordaria macrospora. Spo76 shows an early centromere cleavage associated with an arrest at the first meiotic division and therefore does not form ascospores. Moreover, it exhibits altered pairing structure (synaptonemal complex), reve...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF00447389
更新日期:1986-01-01 00:00:00
abstract::An exceptional mode of mtDNA inheritance involving separate maternal and paternal transmission routes has been reported recently in the mussel Mytilus edulis. This mode of inheritance provides an explanation for the high levels of heteroplasmy for two highly diverged genomes observed in males of this species. Here we ...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF02221509
更新日期:1996-04-01 00:00:00
abstract::The mitochondrial (mt) genome of the sea anemone Metridium senile contains genes for only two transfer RNAs (tRNAs), tRNAf-Met and tRNATrp. Experiments were conducted to seek evidence for the occurrence of functional tRNAs corresponding to these genes and for the participation of nuclear DNA-encoded tRNAs in mt-protei...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/s00294-013-0395-9
更新日期:2013-08-01 00:00:00
abstract::The RNA polymerase II (Pol II) of Schizosaccharomyces pombe is composed of 12 subunits. Subunit Rpb3 has sequence homology with the N-terminal domain of the prokaryotic alpha subunit, which plays a key role in RNA polymerase assembly. Together with the Rpb2 (the beta homologue) and Rpb11 (the second alpha homologue) s...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/s002940100203
更新日期:2001-06-01 00:00:00
abstract::Although cell division is usually portrayed as an equitable process by which a progenitor cell originates two identical daughter cells, there are multiple examples of asymmetric divisions that generate two cells that differ in their content, morphology and/or proliferative potential. The capacity of the cells to gener...
journal_title:Current genetics
pub_type: 杂志文章,评审
doi:10.1007/s00294-020-01074-y
更新日期:2020-08-01 00:00:00
abstract::The wild diastatic yeast Saccharomyces cerevisiae NCYC 625 has been shown to be homozygous for the glucoamylase-specifying gene STA2. spoII-1-mapping has positioned STA2 on chromosome II. Expression of STA2 is suppressed in some but not all diploids capable of sporulation, and is also inhibited by unlinked nuclear sup...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF00314873
更新日期:1990-04-01 00:00:00
abstract::Fourteen nuclear complementation groups of mutants that specifically affect the three mitochondrially-encoded subunits of yeast cytochrome c oxidase have been characterized. Genes represented by these complementation groups are not required for mitochondrial transcription, transcript processing, or translation per se ...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF00405753
更新日期:1987-01-01 00:00:00
abstract::A naturally occurring single base-pair G to A transition, creating a 10/11 near-match close to the essential 11 base-pair core consensus of ARS1, was used to investigate the importance of near-match sequences. The 10/11 near-match can not substitute for the core consensus since an ARS- phenotype is observed when the c...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF00351723
更新日期:1992-09-01 00:00:00
abstract::We have isolated and characterized a Ty element from a yeast cosmid library which exhibits several unusual features: it is flanked by non-homologous delta elements and directly associated with a singular delta element. A tRNA(Glu3) gene and tRNA(Cys) gene are found in conjunction with this element, located in opposite...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF00420606
更新日期:1986-01-01 00:00:00
abstract::A 1,380-bp intervening sequence within the mitochondrial small subunit ribosomal RNA (mt SSU rRNA) gene of the fungus Sclerotinia sclerotiorum has been sequenced and identified as a group-I intron. This is the first report of an intron in the mt SSU rRNA gene. The intron shows close similarity in secondary structure t...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF00313431
更新日期:1995-01-01 00:00:00
abstract::The ribosomal proteins of two ascomycetes Podospora anserina and Saccharomyces cerevisiae, were compared by two dimensional electrophoresis in two different gel systems and we found only five pairs of proteins which have kept homologous physico-chemical properties under these conditions. An immunological analysis was ...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF00396204
更新日期:1984-12-01 00:00:00
abstract::Cellulases belong to the large family of glycosyl hydrolases (GHs) and are produced by a variety of bacteria and fungi. These extracellular enzymes act as endoglucanases (EGs), cellobiohydrolases or beta-glucosidases. In this paper, we describe molecular screening for EGs from the GH family 12. Using three homologous ...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/s00294-002-0290-2
更新日期:2002-05-01 00:00:00
abstract::A main function of ectomycorrhizas, a symbiosis between certain soil fungi and fine roots of woody plants, is the exchange of plant-derived carbohydrates for fungus-derived nutrients. As it is required in large amounts, nitrogen is of special interest. A gene (AmAMT2) coding for a putative fungal ammonium importer was...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/s00294-006-0106-x
更新日期:2007-02-01 00:00:00
abstract::DNA replication checkpoint is a cell signaling pathway that is activated in response to perturbed replication. Although it is crucial for maintaining genomic integrity and cell survival, the exact mechanism of the checkpoint signaling remains to be understood. Emerging evidence has shown that RecQ helicases, a large f...
journal_title:Current genetics
pub_type: 杂志文章,评审
doi:10.1007/s00294-020-01147-y
更新日期:2021-01-11 00:00:00
abstract::Chloroplast DNAs from six different laboratory collections of Euglena gracilis "strain Z" and var. bacillaris were analyzed with restriction endonucleases EcoRI and Bam HI. The most variable portion of the organelle genome is the region containing the ribosomal cistrons. Intraspecific differences occur in both ribosom...
journal_title:Current genetics
pub_type: 杂志文章
doi:10.1007/BF00429820
更新日期:1981-07-01 00:00:00