Abstract：
:Olfactory receptor neurons (ORNs) do not express the typical neuronal intermediate filament proteins (IFPs), the neurofilament triplet proteins. Immunocytochemical evidence shows that ORNs coexpress vimentin and peripherin but distribute them differently. Specifically, ORNs contain vimentin in dendrites, cell bodies, and axons, but not in terminals in glomeruli; peripherin is present in axons, but excluded from dendrites, cell bodies, and terminal glomeruli. In adult rats, ORN axon fascicles are variably stained with antisera for peripherin; in juvenile rats, staining of fascicles is uniform. Staining with antibody to vimentin is uniform in both adult and juvenile ORN axon fascicles. The unusual pattern of IFP expression and intracellular sorting may have implications for the unique plastic and regenerative capacities of these neurons.
journal_name
Neuronjournal_title
Neuronauthors
Gorham JD,Ziff EB,Baker Hdoi
10.1016/0896-6273(91)90300-osubject
Has Abstractpub_date
1991-09-01 00:00:00pages
485-97issue
3eissn
0896-6273issn
1097-4199pii
0896-6273(91)90300-Ojournal_volume
7pub_type
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