Abstract:
:Various antitumor agents induce apoptotic cell death in tumor cells. Since the apoptosis program in tumor cells plays a critical role in the chemotherapy-induced tumor cell killing, it is suggested that the defect in the signaling pathway of apoptosis could cause a new form of multidrug resistance in tumor cells. This article describes the recent findings concerning the mechanisms of chemotherapy-induced apoptosis and discusses the implication of apoptosis resistance in cancer chemotherapy.
journal_name
Cytotechnologyjournal_title
Cytotechnologyauthors
Mashima T,Seimiya H,Chen Z,Kataoka S,Tsuruo Tdoi
10.1023/A:1008058031511subject
Has Abstractpub_date
1998-09-01 00:00:00pages
293-308issue
1-3eissn
0920-9069issn
1573-0778journal_volume
27pub_type
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