IgA nephropathy associated with leukemia and lymphoma: report of two cases.

abstract：BACKGROUND:Erythropoiesis-stimulating agent (ESA) responsiveness is related to the nutritional status of patients on hemodialysis (HD). Serum butyrylcholinesterase (BChE), an alpha-glycoprotein, may decrease in case of malnutrition. We investigated whether BChE was independently related to ESA resistance in patients on...

journal_title：Clinical and experimental nephrology

authors： Okamoto T,Hatakeyama S,Tanaka Y,Imanishi K,Takashima T,Saitoh F,Koie T,Suzuki T,Ohyama C

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Albuminuria is a biomarker for chronic kidney disease and an independent predictor of cardiovascular and all-cause mortality. A recent meta-analysis concluded that these risks increase with urinary albumin concentration, even when below the microalbuminuria threshold. Thus, minimizing urinary albumin may be ...

journal_title：Clinical and experimental nephrology

authors： Yamamoto-Kabasawa K,Hosojima M,Yata Y,Saito M,Tanaka N,Tanaka J,Tanabe N,Narita I,Arakawa M,Saito A

更新日期：2015-12-01 00:00:00

abstract：:Because of the increasing incidence of cardiac failure and chronic renal failure due to the progressive aging of the population, the extensive application of cardiac interventional techniques, the rising rates of obesity and diabetes mellitus, coexistence of heart failure and renal failure in the same patient are freq...

journal_title：Clinical and experimental nephrology

authors： Longhini C,Molino C,Fabbian F

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Achieving a normal final adult height (FH) remains a challenge in the field of pediatric kidney transplantation (KTx). To examine the optimal approach to assuring normal FH following KTx, we retrospectively examined the post-transplant growth and FH of pediatric KTx recipients. METHODS:Since the relevant fa...

journal_title：Clinical and experimental nephrology

authors： Fujii H,Chikamoto H,Akioka Y,Hattori M

更新日期：2014-06-01 00:00:00

abstract：:Unique renal histopathological appearances, consisting of podocytic infolding and microstructures in the glomerular basement membrane (GBM) were identified in the renal biopsies from three patients with collagen diseases such as systemic lupus erythematosus (lupus nephritis, class II) and Sjögren's syndrome. In each c...

journal_title：Clinical and experimental nephrology

authors： Sugiyama H,Maruyama M,Morinaga H,Inoue T,Takiue K,Kikumoto Y,Kinomura M,Sada KE,Akagi S,Kitamura S,Maeshima Y,Makino H

更新日期：2008-12-01 00:00:00

abstract：:This report documents a case of metastatic papillary renal cell carcinoma (PRCC) which successfully responded to interleukin-2 (IL-2) therapy. A 59-year-old male presented with a left renal mass measuring 3.0 cm in diameter and a right adrenal mass measuring 5.0 cm in diameter. He underwent a left partial nephrectomy ...

journal_title：Clinical and experimental nephrology

authors： Kosaka T,Mikami S,Miyajima A,Oya M

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Mizoribine (MZR) has been developed as an immunosuppressive agent, but has a less potent immunosuppressive effect up to 3 mg/kg/day MZR. Therefore, we investigated whether high-dose MZR, at 6 mg/kg/day, would be effective and safe for kidney transplant patients in conjunction with cyclosporine (CsA), basilix...

journal_title：Clinical and experimental nephrology

authors： Yoshimura N,Ushigome H,Akioka K,Nobori S,Suzuki T,Sakai K,Okamoto M

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND AND AIM:The infusion of chronic angiotensin II (Ang II) has been shown to promote renal interstitial fibrosis. To evaluate the pathophysiological significance of the natriuretic peptide-GC-A system, we infused Ang II (1.0 mg/kg/day) in GC-A-deficient mice (GC-A-KO). METHODS:We used 5 groups (Wild-Saline n =...

journal_title：Clinical and experimental nephrology

authors： Yoshihara F,Tokudome T,Kishimoto I,Otani K,Kuwabara A,Horio T,Kawano Y,Kangawa K

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Hypertriglyceridemia (hTG) is a risk factor for progression of chronic kidney disease (CKD); however, it remains unknown whether the adipocytokine complement component 3 (C3) is involved in the association between hTG and CKD. METHODS:The study included 138 patients (54 % male) with non-nephrotic (serum alb...

journal_title：Clinical and experimental nephrology

authors： Kohagura K,Kochi M,Miyagi T,Kinjyo T,Maehara Y,Kinjyo K,Nagahama K,Sakima A,Iseki K,Ohya Y

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:The herbicide paraquat (1, 1'-dimethyl-4, 4'-bipyridylium dichloride; PQ) is a poison well-known to cause delayed mortality due to acute kidney injuries (AKI). This study examines the changes in serum amino acids (AAs) metabolite profiles as surrogate markers of renal cell metabolism and function after paraq...

journal_title：Clinical and experimental nephrology

authors： Wan X,Li X,Wang Q,Zheng B,Zhou C,Kang X,Hu D,Bao H,Peng A

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:The Japanese classification of diabetic nephropathy reflects the risks of mortality, cardiovascular events and kidney prognosis and is clinically useful. Furthermore, pathological findings of diabetic nephropathy are useful for predicting prognoses. In this study, we evaluated the characteristics of patholog...

journal_title：Clinical and experimental nephrology

authors： Furuichi K,Shimizu M,Yuzawa Y,Hara A,Toyama T,Kitamura H,Suzuki Y,Sato H,Uesugi N,Ubara Y,Hohino J,Hisano S,Ueda Y,Nishi S,Yokoyama H,Nishino T,Kohagura K,Ogawa D,Mise K,Shibagaki Y,Makino H,Matsuo S,Wada T,

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:The present study was conducted to clarify the clinical risk factors related to the development of encapsulating peritoneal sclerosis (EPS), which is one of the most serious complications in patients undergoing peritoneal dialysis (PD). METHODS:The records of 78 patients with a history of PD treatment, incl...

journal_title：Clinical and experimental nephrology

authors： Yamamoto R,Otsuka Y,Nakayama M,Maruyama Y,Katoh N,Ikeda M,Yamamoto H,Yokoyama K,Kawaguchi Y,Matsushima M

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:The Determinants of the prescribed dialysis dose have not been well studied in a large patient population. Few studies have examined survival rates after adjusting for dose determinants. METHODS:Data were obtained from a cohort of chronic hemodialysis patients for the period January 1991 through December 20...

journal_title：Clinical and experimental nephrology

authors： Iseki K,Tozawa M,Takishita S

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:There is no obvious evidence regarding biological variation of procalcitonin (PCT) levels in hemodialysis (HD) patients without infections. The aim of this study was to determine the within- and between-person biological variation of PCT levels in HD patients without infections. METHODS:A multicenter, prosp...

journal_title：Clinical and experimental nephrology

authors： Kubo S,Iwasaki M,Horie M,Matsukane A,Hayashi T,Tanaka Y,Hase H,Joki N

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Vascular endothelial cells (VECs) play crucial roles in physiological and pathologic conditions in tissues and organs. Most of these roles are related to VEC plasma membrane proteins. In the kidney, VECs are closely associated with structures and functions; however, plasma membrane proteins in kidney VECs re...

journal_title：Clinical and experimental nephrology

authors： Liu Z,Xu B,Nameta M,Zhang Y,Magdeldin S,Yoshida Y,Yamamoto K,Fujinaka H,Yaoita E,Tasaki M,Nakagawa Y,Saito K,Takahashi K,Yamamoto T

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Vascular calcification is common in chronic kidney disease (CKD) patients, while erythropoietin (EPO) is widely used in the treatment of renal anemia in CKD patients, whether there is a link between the two is still not clear. METHODS:The primary rat vascular smooth muscle cells (VSMCs) and CKD rats were tr...

journal_title：Clinical and experimental nephrology

authors： He J,Zhong X,Zhao L,Gan H

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Although recovery of renal function after an episode of acute kidney injury (AKI) is an important clinical measure of morbidity, predictors of withdrawal from renal replacement therapy (RRT) among AKI patients remain unclear. METHODS:In this single-center retrospective cohort study, we examined the clinical...

journal_title：Clinical and experimental nephrology

authors： Ihara K,Ishigami J,Inoshita S

更新日期：2019-06-01 00:00:00

abstract：:A 52-year-old Japanese female was admitted to our hospital for microhematuria, proteinuria and progressive renal dysfunction. Two years prior to admission, she was diagnosed with lung adenocarcinoma and multiple bone and brain metastases, and was treated with gefitinib (250 mg/day). Treatment for 6 months induced part...

journal_title：Clinical and experimental nephrology

authors： Masutani K,Fujisaki K,Maeda H,Toyonaga J,Inoshima I,Takayama K,Katafuchi R,Hirakata H,Tsuruya K,Iida M

更新日期：2008-10-01 00:00:00

abstract：:A 33-year-old woman was transferred to our hospital with a 5-month history of taking Chinese herbal medicine containing aristolochic acid. She presented with metabolic acidosis, severe anemia, hypophosphatemia and uric aciduria, and generalized aminoaciduria and glycosuria, features which were consistent with the clin...

journal_title：Clinical and experimental nephrology

authors： Kazama I,Matsubara M,Michimata M,Suzuki M,Hatano R,Sato H,Ito S

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Liposomal amphotericin B (L-AMB), a broad-spectrum antifungicidal drug, is often used to treat fungal infections. However, clinical evidence of its use in patients with renal dysfunction, especially those receiving renal replacement therapy (RRT), is limited. Therefore, we evaluated the usage and occurrence ...

journal_title：Clinical and experimental nephrology

authors： Obata Y,Takazono T,Tashiro M,Ota Y,Wakamura T,Takahashi A,Sato K,Miyazaki T,Nishino T,Izumikawa K

更新日期：2020-11-11 00:00:00

abstract：:A Japanese boy aged 14 years presented with gross hematuria associated with mild proteinuria and was diagnosed as having nutcracker syndrome. Magnetic resonance angiography (MRA) revealed significant compression of the left renal vein between the aorta and the superior mesenteric artery with collaterals. A percutaneou...

journal_title：Clinical and experimental nephrology

authors： Tanaka H,Waga S

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Mizoribine (MZR) therapy after cyclophosphamide (CPM) therapy may be an attractive option in patients with steroid-dependent nephrotic syndrome (SDNS) for the purpose of maintaining remission. This is because CPM is administered only once due to its severe side effects such as gonadal toxicity. However, the ...

journal_title：Clinical and experimental nephrology

authors： Mizutani A,Fujinaga S,Sakuraya K,Hirano D,Shimizu T

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:In Japan, systematic evaluation of the histologic parameters of anti-neutrophil cytoplasmic autoantibodies (ANCA)-related vasculitis has been performed according to the Japanese classification by Shigematsu et al. However, this classification is quite different from that of the European Vasculitis Study Grou...

journal_title：Clinical and experimental nephrology

authors： Joh K,Muso E,Shigematsu H,Nose M,Nagata M,Arimura Y,Yumura W,Wada T,Nitta K,Makino H,Taguma Y,Kaneoka H,Suzuki Y,Kobayashi M,Koyama A,Usui J,Hashimoto H,Ozaki S,Tomino Y,Yamagata K

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is a major global problem and is also associated with a decreased health-related quality of life (HRQOL). The aim of this study was to evaluate measured HRQOL based on the new CKD classification including proteinuria stage, and the effect of measured HRQOL on CKD progression and ...

journal_title：Clinical and experimental nephrology

authors： Okubo R,Kai H,Kondo M,Saito C,Yoh K,Morito N,Usui J,Yamagata K

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:The present study aimed to clarify the beneficial effect of allopurinol on cardiovascular morbidity and mortality in a cohort of hypertensive nephropathy patients with impaired kidney function. METHODS:One hundred and seventy-eight patients diagnosed with hypertensive nephropathy and presenting with impaire...

journal_title：Clinical and experimental nephrology

authors： Terawaki H,Nakayama M,Miyazawa E,Murata Y,Nakayama K,Matsushima M,Miyazaki M,Sato H,Sato M,Sato T,Taguma Y,Ito S

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:The suitable methods evaluating glomerular filtration rate (GFR) have not been established in patients undergoing radical nephrectomy (RN) or radical nephroureterectomy (RNU) due to urological malignancies in Japan as well as worldwide. METHODS:We examined the relationship between creatinine clearance-based...

journal_title：Clinical and experimental nephrology

authors： Niwa N,Yoshida T,Mizuno R,Kikuchi E,Miyajima A,Hayashi M,Oya M

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Accurate glomerular filtration rate (GFR) evaluation is significant for drug dosing of carboplatin, anticancer drug excreted mainly from kidney. Serum cystatin-C (sCys-C) is a GFR marker with little affected by body muscle mass volume. And GFR equations based on serum creatinine (eGFRcreat) and sCys-C (eGFRc...

journal_title：Clinical and experimental nephrology

authors： Shibata K,Yasuda Y,Kobayashi R,Ando Y,Shimokata T,Kamiya H,Hayashi M,Maruyama S,Matsuo S,Nakao M,Tsuchiya T,Teramachi H

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Maxacalcitol (22-oxacalcitriol; OCT) is a novel vitamin D analogue. In previous clinical studies, OCT was administered three times a week to hemodialysis patients with refractory secondary hyperparathyroidism (2HPT), in whom it acted by inhibiting parathyroid hormone secretion, as well as causing mildly elev...

journal_title：Clinical and experimental nephrology

authors： Murakami K,Miyachi H,Watanabe A,Kawamura N,Fujii M,Koide S,Murase M,Kushimoto H,Hasegawa M,Tomita M,Hiki Y,Sugiyama S

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Tolvaptan slowed the rates of total kidney volume (TKV) growth and renal function decline over a 3-year period in patients with autosomal dominant polycystic kidney disease (ADPKD) enrolled in the Tolvaptan Efficacy and Safety in Management of Autosomal Dominant Polycystic Kidney Disease and Its Outcomes (TE...

journal_title：Clinical and experimental nephrology

authors： Horie S,Muto S,Kawano H,Okada T,Shibasaki Y,Nakajima K,Ibuki T

更新日期：2021-01-20 00:00:00

abstract：BACKGROUND:IgG4-related disease has attracted wide attention recently. It is characterized by a high level of serum IgG4 and dense infiltration of IgG4-positive plasma cells into multiple organs, with the kidney being one representative target. Although several sets of diagnostic criteria for autoimmune pancreatitis (A...

journal_title：Clinical and experimental nephrology

authors： Kawano M,Saeki T,Nakashima H,Nishi S,Yamaguchi Y,Hisano S,Yamanaka N,Inoue D,Yamamoto M,Takahashi H,Nomura H,Taguchi T,Umehara H,Makino H,Saito T

更新日期：2011-10-01 00:00:00