Abstract:
:The objective of the study was to determine the prevalence of known diabetes among elderly subjects receiving nursing care in a north Norwegian population, to screen for new cases using HbA1c measurement and to evaluate the quality of care for those with diabetes. Men and women, with and without known diabetes, above 69 years and receiving nursing care either in an institution or in their own home in the municipality of Tromsø, were included. A health questionnaire was administered and HbA1c measured. An oral glucose tolerance test (OGTT) was performed in those with HbA1c > 6.5% (upper reference limit). A total of 788 subjects were evaluated for participation and 228 completed the study. Forty-six subjects (20.2%) had a previous diagnosis of diabetes. Their age was 80.1+/-5.9 years (mean+/-SD) and HbA1c level 7.6+/-1.4%. Most patients had their blood glucose measured weekly and 65% used blood pressure medication; on average they were seen by their private doctor four times a year and annually by an ophthalmologist. Six subjects with undiagnosed diabetes had HbA1c > 6.5%. Diabetes was confirmed in one, excluded in two and further testing declined in three. None of these six subjects had HbA1c > 7.0%. In conclusion, there is a high prevalence of diabetes among elderly subjects needing nursing care. The prevalence of undiagnosed diabetes in need of treatment, as evaluated by the HbA1c level, was low, indicating that the focus on diabetes and quality of care for the elderly in our area is fairly good.
journal_name
Acta Diabetoljournal_title
Acta diabetologicaauthors
Jorde R,Hagen Tdoi
10.1007/s00592-006-0212-8subject
Has Abstractpub_date
2006-08-01 00:00:00pages
52-6issue
2eissn
0940-5429issn
1432-5233journal_volume
43pub_type
杂志文章abstract::The aim of this study was to evaluate lipid peroxidation and scavenging enzyme activity in streptozotocin-induced diabetes, and then to establish whether moderate doses of nonenzymatic antioxidant vitamin E play a role in the antioxidant defence system in diabetic pregnant rats and their offspring. The study group con...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s005920070002
更新日期:2000-01-01 00:00:00
abstract::Most reports of outcome following obesity surgery report weight and co-morbidity changes only. We studied body composition changes in 17 adult patients (15 F, 2 M, age 43+/-2 years, range 28-58 years), with morbid obesity (initial BMI 40.4+/-4.9 kg/m(2), range 34.7-48.8) who were managed surgically by laparoscopically...
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doi:10.1007/s00592-003-0083-1
更新日期:2003-10-01 00:00:00
abstract::The aim of the study is to evaluate the prevalence and incidence of myocardial dysfunction (MD) and heart failure (HF) in long-lasting (≥10 years) type 1 diabetes without cardiovascular disorders or with hypertension or coronary heart disease (CHD). The study included 1,685 patients with type 1 diabetes (mean baseline...
journal_title:Acta diabetologica
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doi:10.1007/s00592-013-0455-0
更新日期:2013-08-01 00:00:00
abstract:AIMS:Genetic polymorphisms may contribute to platelet reactivity in diabetic patients; however, the information on their influence on long-term antiplatelet therapy is lacking. Our aim was to evaluate the role of previously described genetic variants and platelet reactivity on risk of all-cause mortality and cardiovasc...
journal_title:Acta diabetologica
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00592-016-0945-y
更新日期:2017-04-01 00:00:00
abstract:AIMS:The aim of the study was to evaluate and compare continuous subcutaneous insulin infusion (CSII) use in pediatric and adult age groups. METHODS:Data were collected with a questionnaire sent by e-mail to CSII-experienced Diabetes Centers. The questionnaire assessed: (1) number of CSII-treated patients; (2) patient...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-015-0810-4
更新日期:2016-06-01 00:00:00
abstract::Continuous subcutaneous insulin infusion (CSII) is effective and safe in children and adults with type 1 diabetes. Notwithstanding, some patients decide to discontinue using CSII. We evaluated the discontinuation rate, and its related factors, in a large group of children and adolescents with type 1 diabetes using CSI...
journal_title:Acta diabetologica
pub_type: 杂志文章,多中心研究
doi:10.1007/s00592-011-0344-3
更新日期:2012-12-01 00:00:00
abstract:AIMS:The aim of the current study was to investigate the association of type 2 diabetes (T2D) and insulin treatment with changes in muscle mass, muscle strength, and physical performance in older adults. METHODS:In 731 participants of the population-based KORA-Age study aged 74.6 ± 6.2 years (T2D: n = 118; insulin tre...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-020-01523-7
更新日期:2020-09-01 00:00:00
abstract::Preliminary evidence from trials with the HMG-CoA reductase inhibitors (statins), simvastatin and pravastatin, suggests that aggressive treatment of diabetic dyslipidaemia will reduce coronary events. Questions regarding the prevention of cardiovascular events in diabetic patients are now being addressed in prospectiv...
journal_title:Acta diabetologica
pub_type: 杂志文章,评审
doi:10.1007/s005920170005
更新日期:2001-01-01 00:00:00
abstract::Recent studies have reported that elevated proinsulin levels are indicative of an increased cardiovascular risk. Renal proximal tubular cells represent a major site for the metabolism of insulin-like hormones after glomerular filtration into the tubular lumen. To determine the binding and degradation of proinsulin in ...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/BF00569428
更新日期:1996-07-01 00:00:00
abstract::Genetic markers may be used to improve the prediction of insulin-dependent diabetes mellitus (type 1) in individuals with islet autoantibodies. In order to develop a risk assessment strategy for the Lombardy region of northern Italy based on genetic and immunological markers, we analyzed HLA DQA1 and DQB1 alleles in 6...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/BF00838481
更新日期:1995-10-01 00:00:00
abstract:AIMS:Glucagon is used to resolve severe hypoglycemia in unconscious patients with diabetes, requiring third-party assistance. A few studies have shown that intranasal (IN) glucagon causes resolution of hypoglycemia in insulin-treated patients with type 1 (T1DM) diabetes. This systematic review and meta-analysis updates...
journal_title:Acta diabetologica
pub_type: 杂志文章,meta分析
doi:10.1007/s00592-020-01483-y
更新日期:2020-06-01 00:00:00
abstract::This study examined whether or not changes in plasma concentrations of motilin and other gastrointestinal hormones known to affect gastric motility are associated with the accelerated gastric emptying seen during hypoglycaemia. While studying gastric emptying by scintigraphy in eight healthy subjects, the plasma conce...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s005920050073
更新日期:1997-10-01 00:00:00
abstract:AIMS:This study aimed to assess islet insulin secretion and insulin resistance in Chinese patients with latent autoimmune diabetes in adults (LADA). METHODS:Twelve patients with LADA, 10 with type 1 diabetes mellitus (T1DM), 10 with type 2 diabetes mellitus (T2DM), and 10 nondiabetic healthy controls (HCs) were includ...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-019-01387-6
更新日期:2019-11-01 00:00:00
abstract::Overload of reactive oxygen species during diabetes is known to impair cellular homeostasis and to promote deterioration of membrane function in the organism. The aim of the present study was to examine the effect of dietary supplementation with the pyridoindole atioxidant stobadine on functional properties of the ren...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-004-0162-y
更新日期:2004-12-01 00:00:00
abstract:AIMS:Familial partial lipodystrophy (FPLD) is a rare autosomal dominant disorder, mostly due to mutations in lamin A (LMNA) or in peroxisome proliferator-activated receptor gamma (PPARG) genes. In the present study, we aimed to identify and functionally characterize the genetic defect underlying FPLD in an Italian fami...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-019-01462-y
更新日期:2020-05-01 00:00:00
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journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-012-0373-6
更新日期:2013-10-01 00:00:00
abstract:AIMS:Haptoglobin (Hp) genotype 2-2 increases cardiovascular diabetes complications. In type 2 diabetes, α-tocopherol was shown to lower cardiovascular risk in Hp 2-2, potentially through HDL function improvements. Similar type 1 diabetes data are lacking. We conducted a randomized crossover pilot of α-tocopherol supple...
journal_title:Acta diabetologica
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00592-015-0770-8
更新日期:2016-04-01 00:00:00
abstract::The aim of this study was to investigate the influence of homocysteine (hcy) levels on endothelial function by the method of brachial artery ultrasonography and their relation with microvascular complications in type 2 diabetes mellitus (T2DM) patients without macrovascular disease. Fifty-nine T2DM patients with a mea...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-007-0245-7
更新日期:2007-06-01 00:00:00
abstract:AIM:Infection of a diabetic foot ulcer (DFU) is common. More than the half of DFUs become infected and 15-20% of them necessitate amputation in course of treatment. Diabetic foot infection (DFI) is therefore the major cause for non-traumatic lower limb amputation in Germany. Prompt and effective treatment of DFI is man...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-020-01587-5
更新日期:2020-09-17 00:00:00
abstract::Diabetic kidney disease (DKD) is a devastating complication of Type 1 and Type 2 diabetes and leads to increased morbidity and mortality. Earlier work in families has provided strong evidence that heredity is a major determinant of DKD. Previous linkage analyses and candidate gene studies have identified potential DKD...
journal_title:Acta diabetologica
pub_type: 杂志文章,评审
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更新日期:2018-11-01 00:00:00
abstract:AIMS:Maternal type 2 diabetes (T2D) can result in adverse pathological outcomes to both the mother and fetus. The present study aimed to investigate the pathological effects of maternal T2D on the gene expression patterns and functions of fetal human umbilical vein endothelial cells (HUVECs), a representative of fetal ...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-018-1207-y
更新日期:2019-01-01 00:00:00
abstract::We analysed the risk factors associated with diabetic complications in the cohort of patients assisted by a type 2 diabetes mellitus (T2DM) shared-care program. We analysed registry data from 16,136 T2DM patients. Of them, 4,781 had microangiopathy, 3,469 CV events. They were 70.5 ± 17.1 years old, 50% were male, dise...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-010-0186-4
更新日期:2010-12-01 00:00:00
abstract::This study was aimed at the assessment of incidence of malignancies in type 2 diabetic patients treated with different sulphonylureas. A matched case-control study was performed. Cases were 195 diabetic patients aged 69.0 +/- 9.2 years who had an incident malignancy. Controls were 195 diabetic patients, unaffected by ...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-008-0083-2
更新日期:2009-12-01 00:00:00
abstract:AIMS:High glycemic variability (GV) is the major indication for islet transplantation (IT) in patients with type 1 diabetes (T1D). The actual criteria used to assess graft function do not consider GV improvement. Our study aimed to describe GV indices' evolution in T1D patients who benefited from IT during the TRIMECO ...
journal_title:Acta diabetologica
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00592-019-01425-3
更新日期:2020-03-01 00:00:00
abstract::Aim of this study was to formulate an index for glucose effectiveness (Sg), SgIo, based on 3-point (0, 30 and 120 min) 75 g oral glucose tolerance test (OGTT). The equation for SgI(O) was developed in the Chikuma cohort (n = 502). Firstly, post-loading plasma glucose without insulin action and Sg (PPG-without insulin ...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-012-0417-y
更新日期:2012-12-01 00:00:00
abstract::Hyperglycaemia caused by stress and inflammation is common during critical illness. We hypothesised that a latent glucose metabolism disturbance contributes to development of hyperglycaemia and that those patients have increased risk for diabetes. We included patients with sepsis, acute coronary syndrome and acute hea...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-009-0115-6
更新日期:2010-12-01 00:00:00
abstract::The aim of this study was to evaluate the influence of endogenous insulin levels and of insulin administration on coronary heart disease (CHD) and on mortality in a cohort of patients with long-standing non-insulin-dependent diabetes mellitus (type 2). In a cross-sectional study, 93 patients (known duration 17 +/- 8 y...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s005920050101
更新日期:1998-04-01 00:00:00
abstract::Administration of exogenous insulin for the treatment of diabetes is often accompanied by the development of insulin antibodies (IA). These antibodies may affect the patient's requirement for insulin by acting as an insulin binding reservoir. The improvement of insulin purification in the 1970s and the development of ...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s00592-009-0135-2
更新日期:2010-06-01 00:00:00
abstract::We have measured protein phosphatase (PP) activity in crude homogenates as well as in the total 105.000 x g supernatant and precipitate fractions from normal rat pancreatic islets. On the basis of the inhibition produced by either 1 nM or 1 microM okadaic acid, both PP1 and PP2A activity were present in crude islet ho...
journal_title:Acta diabetologica
pub_type: 杂志文章
doi:10.1007/s005920050057
更新日期:1997-03-01 00:00:00
abstract:AIMS:To evaluate the methodological quality of systematic reviews (SRs), and summarize evidence of important outcomes from dipeptidyl peptidase-4 inhibitors (DPP4-I) in treating type 2 diabetes mellitus (T2DM). METHODS:We included SRs of DPP4-I for the treatment of T2DM until January, 2018 by searching the Cochrane Li...
journal_title:Acta diabetologica
pub_type: 杂志文章,评审
doi:10.1007/s00592-018-1164-5
更新日期:2019-01-01 00:00:00